PDB: 47120 件ウェブページステータス検索Chemie searchBIRD

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8EKW	Cryo-EM structure of human PRDX4 分子名称: Peroxiredoxin-4 著者 Su, C.C. 登録日 2022-09-22 公開日 2023-05-03 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (2.83 Å) 主引用文献 High-resolution structural-omics of human liver enzymes. Cell Rep, 42, 2023
8SS3	Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to competitive antagonist ZK and channel blocker spermidine (closed state) 分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL, Digitonin, ... 著者 Gangwar, S.P, Yen, L.Y, Yelshanskaya, M.V, Sobolevsky, A.I. 登録日 2023-05-08 公開日 2023-09-06 最終更新日 2023-11-01 実験手法 ELECTRON MICROSCOPY (3.21 Å) 主引用文献 Modulation of GluA2-gamma 5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2. Nat.Struct.Mol.Biol., 30, 2023
8SS2	Structure of AMPA receptor GluA2 complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to competitive antagonist ZK and channel blocker spermidine (closed state) 分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL, Digitonin, ... 著者 Gangwar, S.P, Yen, L.Y, Yelshanskaya, M.V, Sobolevsky, A.I. 登録日 2023-05-08 公開日 2023-09-06 最終更新日 2023-11-01 実験手法 ELECTRON MICROSCOPY (3.58 Å) 主引用文献 Modulation of GluA2-gamma 5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2. Nat.Struct.Mol.Biol., 30, 2023
6EAA	X-ray crystal structure of Pf-M1 in complex with inhibitor (6i) and catalytic zinc ion 分子名称: GLYCEROL, M1 family aminopeptidase, MAGNESIUM ION, ... 著者 Drinkwater, N, McGowan, S. 登録日 2018-08-02 公開日 2018-12-26 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Hydroxamic Acid Inhibitors Provide Cross-Species Inhibition of Plasmodium M1 and M17 Aminopeptidases. J. Med. Chem., 62, 2019
4KWG	Crystal Structure Analysis of ALDH2+ALDiB13 分子名称: 1,2-ETHANEDIOL, 7-bromo-5-methyl-1H-indole-2,3-dione, Aldehyde dehydrogenase, ... 著者 Hurley, T.D, Kimble-Hill, A.C. 登録日 2013-05-24 公開日 2014-04-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Development of selective inhibitors for aldehyde dehydrogenases based on substituted indole-2,3-diones. J.Med.Chem., 57, 2014
8SS9	Structure of LBD-TMD of AMPA receptor GluA2 in complex with auxiliary subunit TARP gamma-5 bound to competitive antagonist ZK and antiepileptic drug perampanel (closed state) 分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-(6'-oxo-1'-phenyl[1',6'-dihydro[2,3'-bipyridine]]-5'-yl)benzonitrile, CHOLESTEROL, ... 著者 Gangwar, S.P, Yen, L.Y, Yelshanskaya, M.V, Sobolevsky, A.I. 登録日 2023-05-08 公開日 2023-09-06 最終更新日 2023-10-25 実験手法 ELECTRON MICROSCOPY (2.72 Å) 主引用文献 Modulation of GluA2-gamma 5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2. Nat.Struct.Mol.Biol., 30, 2023
8SS6	Structure of AMPA receptor GluA2 complex with auxiliary subunits TARP gamma-5 and cornichon-2 bound to competitive antagonist ZK, channel blocker spermidine and antiepileptic drug perampanel (closed state) 分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-(6'-oxo-1'-phenyl[1',6'-dihydro[2,3'-bipyridine]]-5'-yl)benzonitrile, CHOLESTEROL, ... 著者 Gangwar, S.P, Yen, L.Y, Yelshanskaya, M.V, Sobolevsky, A.I. 登録日 2023-05-08 公開日 2023-09-06 最終更新日 2023-11-01 実験手法 ELECTRON MICROSCOPY (3.01 Å) 主引用文献 Modulation of GluA2-gamma 5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2. Nat.Struct.Mol.Biol., 30, 2023
4KZF	The mechanism of the amidases: The effect of the mutation E142L in the amidase from Geobacillus pallidus 分子名称: Aliphatic amidase, CHLORIDE ION 著者 Weber, B.W, Sewell, B.T, Kimani, S.W, Varsani, A, Cowan, D.A, Hunter, R. 登録日 2013-05-29 公開日 2013-08-21 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 The mechanism of the amidases: mutating the glutamate adjacent to the catalytic triad inactivates the enzyme due to substrate mispositioning. J.Biol.Chem., 288, 2013
8SDA	CryoEM structure of rat Kv2.1(1-598) L403A mutant in nanodiscs 分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, POTASSIUM ION, Potassium voltage-gated channel subfamily B member 1 著者 Tan, X, Swartz, K.J. 登録日 2023-04-06 公開日 2023-09-27 最終更新日 2023-10-25 実験手法 ELECTRON MICROSCOPY (3.32 Å) 主引用文献 Inactivation of the Kv2.1 channel through electromechanical coupling. Nature, 622, 2023
4KZK	The structure of the periplasmic L-arabinose binding protein from Burkholderia thailandensis 分子名称: L-arabinose ABC transporter, periplasmic L-arabinose-binding protein, beta-D-galactopyranose 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2013-05-30 公開日 2013-06-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 The structure of the periplasmic L-arabinose binding protein from Burkholderia thailandensis TO BE PUBLISHED
8SD3	CryoEM structure of rat Kv2.1(1-598) wild type in nanodiscs 分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, POTASSIUM ION, Potassium voltage-gated channel subfamily B member 1 著者 Tan, X, Swartz, K.J. 登録日 2023-04-06 公開日 2023-09-27 最終更新日 2023-10-25 実験手法 ELECTRON MICROSCOPY (2.95 Å) 主引用文献 Inactivation of the Kv2.1 channel through electromechanical coupling. Nature, 622, 2023
6EFC	Hsa Siglec + Unique domains (unliganded) 分子名称: CALCIUM ION, SODIUM ION, Streptococcal hemagglutinin 著者 Iverson, T.M. 登録日 2018-08-16 公開日 2020-02-19 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Origins of glycan selectivity in streptococcal Siglec-like adhesins suggest mechanisms of receptor adaptation. Nat Commun, 13, 2022
6EGU	Structure of RVFV envelope protein Gc in postfusion conformation in complex with 1,2-dipropionyl-sn-glycero-3-phosphocholine 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, RVFV ENVELOPE PROTEIN GC, [(2R)-3-[oxidanyl-[2-(trimethyl-$l^{4}-azanyl)ethoxy]phosphoryl]oxy-2-propanoyloxy-propyl] propanoate, ... 著者 Guardado-Calvo, P, Rey, F.A. 登録日 2017-09-12 公開日 2017-11-01 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 A glycerophospholipid-specific pocket in the RVFV class II fusion protein drives target membrane insertion. Science, 358, 2017
6EH0	Apo crystal structure of the Protein-Kinase A catalytic subunit from Criteculus 分子名称: cAMP-dependent protein kinase catalytic subunit alpha 著者 Mueller, J.M, Heine, A, Klebe, G. 登録日 2017-09-12 公開日 2018-10-10 最終更新日 2019-05-15 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Conceptional Design of Self-Assembling Bisubstrate-like Inhibitors of Protein Kinase A Resulting in a Boronic Acid Glutamate Linkage Acs Omega, 2019
8SE6	NKG2D complexed with inhibitor 36 分子名称: N-[(1S)-2-(dimethylamino)-2-oxo-1-{3-[3-(2,2,2-trifluoroethyl)azetidin-1-yl]phenyl}ethyl]-4'-(trifluoromethyl)[1,1'-biphenyl]-2-carboxamide, NKG2-D type II integral membrane protein, TETRAETHYLENE GLYCOL, ... 著者 Thompson, A.A, Grant, J.C, Karpowich, N.K, Sharma, S. 登録日 2023-04-08 公開日 2023-10-11 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.36 Å) 主引用文献 Development of small molecule inhibitors of natural killer group 2D receptor (NKG2D). Bioorg.Med.Chem.Lett., 96, 2023
6EHR	The crystal structure of the human LAMTOR-RagA CTD-RagC CTD complex 分子名称: Ragulator complex protein LAMTOR1, Ragulator complex protein LAMTOR2, Ragulator complex protein LAMTOR3, ... 著者 Scheffzek, K, Naschberger, A. 登録日 2017-09-14 公開日 2017-10-04 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.898 Å) 主引用文献 Crystal structure of the human lysosomal mTORC1 scaffold complex and its impact on signaling. Science, 358, 2017
8EFY	Structure of double homo-hexameric AAA+ ATPase RuvB motors 分子名称: ADENOSINE-5'-DIPHOSPHATE, Holliday junction ATP-dependent DNA helicase RuvB, MAGNESIUM ION, ... 著者 Shen, Z.F, Rish, A.D, Fu, T.M. 登録日 2022-09-10 公開日 2023-05-10 実験手法 ELECTRON MICROSCOPY (3.16 Å) 主引用文献 Structure of double homo-hexameric AAA+ ATPase RuvB motor binding with DNA substrate To Be Published
4L4D	Structure of cyanide and camphor bound P450cam mutant L358A 分子名称: CAMPHOR, CYANIDE ION, Camphor 5-monooxygenase, ... 著者 Batabyal, D, Li, H, Poulos, T.L. 登録日 2013-06-07 公開日 2013-07-31 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.104 Å) 主引用文献 Synergistic Effects of Mutations in Cytochrome P450cam Designed To Mimic CYP101D1. Biochemistry, 52, 2013
6EJS	Nuclease NucB from Bacillus licheniformis in P212121 space group 分子名称: Nuclease, SULFATE ION 著者 Stransky, J, Dohnalek, J, Oestergaard, L.A. 登録日 2017-09-23 公開日 2019-04-10 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure of novel nuclease NucB from Bacillus licheniformis To Be Published
4L58	Crystal structure of the MLL5 PHD finger in complex with H3K4me3 分子名称: Histone H3 peptide, Histone-lysine N-methyltransferase MLL5, ZINC ION 著者 Tong, Q, Ali, M, Kutateladze, T.G. 登録日 2013-06-10 公開日 2013-06-26 最終更新日 2013-07-24 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Molecular basis for chromatin binding and regulation of MLL5. Proc.Natl.Acad.Sci.USA, 110, 2013
8EMT	Cryo-EM analysis of the human aldehyde oxidase from liver 分子名称: Aldehyde oxidase, DIOXOTHIOMOLYBDENUM(VI) ION, FE2/S2 (INORGANIC) CLUSTER, ... 著者 Su, C, Lyu, M, Zhang, Z, Yu, E.W. 登録日 2022-09-28 公開日 2023-05-10 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (2.92 Å) 主引用文献 High-resolution structural-omics of human liver enzymes. Cell Rep, 42, 2023
6EKN	Crystal structure of MMP12 in complex with inhibitor BE7. 分子名称: (2~{S})-2-[2-[4-(4-methoxyphenyl)phenyl]sulfonylphenyl]pentanedioic acid, 1,2-ETHANEDIOL, CALCIUM ION, ... 著者 Ciccone, L, Tepshi, L, Nuti, E, Rossello, A, Stura, E.A. 登録日 2017-09-26 公開日 2018-05-16 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Development of Thioaryl-Based Matrix Metalloproteinase-12 Inhibitors with Alternative Zinc-Binding Groups: Synthesis, Potentiometric, NMR, and Crystallographic Studies. J. Med. Chem., 61, 2018
6EKV	Structure of OrfX2 from Clostridium botulinum A2 分子名称: SULFATE ION, Toxin complex component ORF-X2 著者 Gustafsson, R, Berntsson, R.P, Stenmark, P. 登録日 2017-09-27 公開日 2017-10-25 最終更新日 2018-01-31 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structures of OrfX2 and P47 from a Botulinum neurotoxin OrfX-type gene cluster. FEBS Lett., 591, 2017
6EN0	Structure of the Tn1549 transposon Integrase (aa 82-397) in complex with circular intermediate DNA (CI5-DNA) 分子名称: DNA (44-MER), Int protein 著者 Rubio-Cosials, A, Barabas, O. 登録日 2017-10-04 公開日 2018-04-04 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Transposase-DNA Complex Structures Reveal Mechanisms for Conjugative Transposition of Antibiotic Resistance. Cell, 173, 2018
8SRP	FoxP3 forms Ladder-like multimer to bridge TTTG repeats 分子名称: DNA 72-mer, Forkhead box protein P3 著者 Leng, F, Hur, S. 登録日 2023-05-05 公開日 2023-10-18 最終更新日 2023-12-27 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 FOXP3 recognizes microsatellites and bridges DNA through multimerization. Nature, 624, 2023

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