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5AVG
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BU of 5avg by Molmil
The 0.95 angstrom structure of thaumatin crystallized in high-strength agarose hydrogel
分子名称: Thaumatin-1
著者Sugiyama, S, Shimizu, N, Maruyama, M, Sazaki, G, Hirose, M, Adachi, H, Takano, K, Murakami, S, Inoue, T, Mori, Y, Matsumura, H.
登録日2015-06-16
公開日2015-07-08
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (0.95 Å)
主引用文献Growth of protein crystals in hydrogels prevents osmotic shock
J.Am.Chem.Soc., 134, 2012
7YZJ
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BU of 7yzj by Molmil
FAB IN COMPLEX WITH ANTIGENIC PEPTIDE OF INTERLEUKIN-2
分子名称: Antigenic peptide, Heavy chain of FAB fragment, Light chain of FAB fragment
著者Pletnev, V, Pletneva, N.
登録日2022-02-20
公開日2023-02-01
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Three-Dimensional Structure of Fab Fragment of Monoclonal Antibody LNKB-2 Complexed with Antigenic Nonapeptide from Human Interleukin-2
Russ.J.Bioorganic Chem., 2023
7YMQ
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BU of 7ymq by Molmil
Crystal structure of lysoplasmalogen specific phopholipase D, F211L mutant
分子名称: Lysoplasmalogenase
著者Murayama, K, Kato-Murayama, M, Sugimori, D, Shirouzu, M, Hamana, H.
登録日2022-07-29
公開日2023-02-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Structural basis for the substrate specificity switching of lysoplasmalogen-specific phospholipase D from Thermocrispum sp. RD004668.
Biosci.Biotechnol.Biochem., 87, 2022
7D4S
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BU of 7d4s by Molmil
apo-form cyclic trinucleotide synthase CdnD
分子名称: Cyclic AMP-AMP-GMP synthase, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, MAGNESIUM ION
著者Yang, C.-S, Hou, M.-H, Tsai, C.-L, Wang, Y.-C, Ko, T.-P, Chen, Y.
登録日2020-09-24
公開日2021-03-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Crystal structure and functional implication of a bacterial cyclic AMP-AMP-GMP synthetase.
Nucleic Acids Res., 49, 2021
7D4O
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BU of 7d4o by Molmil
cyclic trinucleotide synthase CdnD in complex with ATP and ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cyclic AMP-AMP-GMP synthase, ...
著者Yang, C.-S, Hou, M.-H, Tsai, C.-L, Wang, Y.-C, Ko, T.-P, Chen, Y.
登録日2020-09-24
公開日2021-03-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Crystal structure and functional implication of a bacterial cyclic AMP-AMP-GMP synthetase.
Nucleic Acids Res., 49, 2021
7YMP
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BU of 7ymp by Molmil
Crystal structure of lysoplasmalogen specific phospholipase D
分子名称: Lysoplasmalogenase
著者Murayama, K, Kato-Murayama, M, Sugimori, D, Shirouzu, M, Hamana, H.
登録日2022-07-29
公開日2023-02-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Structural basis for the substrate specificity switching of lysoplasmalogen-specific phospholipase D from Thermocrispum sp. RD004668.
Biosci.Biotechnol.Biochem., 87, 2022
5AOX
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BU of 5aox by Molmil
Human Alu RNA retrotransposition complex in the ribosome-stalling conformation
分子名称: ACETATE ION, ALU JO CONSENSUS RNA, DI(HYDROXYETHYL)ETHER, ...
著者Ahl, V, Weichenrieder, O.
登録日2015-09-12
公開日2015-11-11
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Retrotransposition and Crystal Structure of an Alu Rnp in the Ribosome-Stalling Conformation.
Mol.Cell, 60, 2015
5AQN
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BU of 5aqn by Molmil
Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BAG FAMILY MOLECULAR CHAPERONE REGULATOR 1, BENZOFURO[3,2-D]PYRIMIDIN-4(3H)-ONE, ...
著者Jones, A.M, Westwood, I.M, Osborne, J.D, Matthews, T.P, Cheeseman, M.D, Rowlands, M.G, Jeganathan, F, Burke, R, Lee, D, Kadi, N, Liu, M, Richards, M, McAndrew, C, Yahya, N, Dobson, S.E, Jones, K, Workman, P, Collins, I, van Montfort, R.L.M.
登録日2015-09-22
公開日2016-10-05
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms.
Sci Rep, 6, 2016
5AQU
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BU of 5aqu by Molmil
Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues
分子名称: (1S,2R,3R,5R)-3-(HYDROXYMETHYL)-5-((5-METHOXYQUINAZOLIN-4-YL)AMINO)CYCLOPENTANE-1,2-DIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BAG FAMILY MOLECULAR CHAPERONE REGULATOR 1, ...
著者Jones, A.M, Westwood, I.M, Osborne, J.D, Matthews, T.P, Cheeseman, M.D, Rowlands, M.G, Jeganathan, F, Burke, R, Lee, D, Kadi, N, Liu, M, Richards, M, McAndrew, C, Yahya, N, Dobson, S.E, Jones, K, Workman, P, Collins, I, van Montfort, R.L.M.
登録日2015-09-22
公開日2016-10-05
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms.
Sci Rep, 6, 2016
7D14
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BU of 7d14 by Molmil
Mouse KCC2
分子名称: Solute carrier family 12 member 5
著者Zhang, S, Yang, M.
登録日2020-09-13
公開日2021-04-14
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献The structural basis of function and regulation of neuronal cotransporters NKCC1 and KCC2.
Commun Biol, 4, 2021
7Z3R
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BU of 7z3r by Molmil
Crystal structure of the mouse leptin:LepR-IgCRH2 complex to 2.95 A resolution.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Leptin, Leptin receptor
著者Verstraete, K, Verschueren, K, Savvides, S.N, Tsirigotaki, A.
登録日2022-03-02
公開日2023-03-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.951 Å)
主引用文献Mechanism of receptor assembly via the pleiotropic adipokine Leptin.
Nat.Struct.Mol.Biol., 30, 2023
5AQG
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BU of 5aqg by Molmil
Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues
分子名称: (2R,3R,4S,5R)-2-(3-AMINO-5-METHYL-1,4,5,6,8-PENTAAZAACENAPHTHYLEN-1(5H)-YL)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BAG FAMILY MOLECULAR CHAPERONE REGULATOR 1, ...
著者Jones, A.M, Westwood, I.M, Osborne, J.D, Matthews, T.P, Cheeseman, M.D, Rowlands, M.G, Jeganathan, F, Burke, R, Lee, D, Kadi, N, Liu, M, Richards, M, McAndrew, C, Yahya, N, Dobson, S.E, Jones, K, Workman, P, Collins, I, van Montfort, R.L.M.
登録日2015-09-22
公開日2016-10-05
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms.
Sci Rep, 6, 2016
5AYP
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BU of 5ayp by Molmil
Crystal structure of Bacillus stearothermophilus Farnesyl pyrophosphate synthase
分子名称: Farnesyl diphosphate synthase
著者Makabe, K, Kijima, T.
登録日2015-08-26
公開日2016-09-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Crystal structure of Bacillus stearothermophilus Farnesyl pyrophosphate synthase
To Be Published
5B6X
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BU of 5b6x by Molmil
A three dimensional movie of structural changes in bacteriorhodopsin: structure obtained 760 ns after photoexcitation
分子名称: 2,3-DI-PHYTANYL-GLYCEROL, Bacteriorhodopsin, DECANE, ...
著者Royant, A, Nango, E, Nakane, T, Tanaka, T, Arima, T, Neutze, R, Iwata, S.
登録日2016-06-02
公開日2016-12-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A three-dimensional movie of structural changes in bacteriorhodopsin
Science, 354, 2016
5BMF
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BU of 5bmf by Molmil
Crystal Structure of a Theophylline binding antibody Fab fragment
分子名称: 2-(5-{1-[1-(1,3-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)-4,15-dioxo-8,11-dioxa-5,14-diazaicosan-20-yl]-3,3-dimethyl-6-sulfo-1,3-dihydro-2H-indol-2-ylidene}penta-1,3-dien-1-yl)-1-ethyl-3,3-dimethyl-3H-indolium-5-sulfonate, Fab fragment heavy chain, Fab fragment light chain
著者Bujotzek, A, Fuchs, A, Changtao, Q, Klostermann, S, Benz, J, Antes, I, Dengl, S, Hoffmann, E, Georges, G.
登録日2015-05-22
公開日2015-07-29
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献MoFvAb: Modeling the Fv region of antibodies.
Mabs, 7, 2015
7ZD4
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BU of 7zd4 by Molmil
Crystal structure of Pseudomonas aeruginosa S-adenosyl-L-homocysteine hydrolase soaked with Cu+ ions
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE, Adenosylhomocysteinase, ...
著者Malecki, P.H, Gawel, M, Brzezinski, K.
登録日2022-03-29
公開日2023-04-19
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Crystal structure of Pseudomonas aeruginosa S-adenosyl-L-homocysteine hydrolase soaked with Cu+ ions
To Be Published
7DQK
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BU of 7dqk by Molmil
A nicotine MATE transporter, Nicotiana tabacum MATE2 (NtMATE2)
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Tanaka, Y, Tsukazaki, T, Sasaki, A, Iwaki, S.
登録日2020-12-24
公開日2021-06-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Crystal structures of a nicotine MATE transporter provide insight into its mechanism of substrate transport.
Febs Lett., 595, 2021
5BRM
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BU of 5brm by Molmil
Structural basis for Mob1-dependent activation of the core Mst-Lats kinase cascade in Hippo signaling
分子名称: MOB kinase activator 1A, Serine/threonine-protein kinase 3, ZINC ION
著者Luo, X, Ni, L.
登録日2015-05-31
公開日2015-07-08
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.651 Å)
主引用文献Structural basis for Mob1-dependent activation of the core Mst-Lats kinase cascade in Hippo signaling.
Genes Dev., 29, 2015
5BV0
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BU of 5bv0 by Molmil
Crystal Structure of a Complex Between the SNARE Nyv1 and the HOPS Vps33-Vps16 subcomplex from Chaetomium thermophilum
分子名称: SM (Sec1/Munc18-like) protein, SNARE domain, Vps16
著者Baker, R.W, Jeffrey, P.D, Hughson, F.M.
登録日2015-06-04
公開日2015-08-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献A direct role for the Sec1/Munc18-family protein Vps33 as a template for SNARE assembly.
Science, 349, 2015
5B21
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BU of 5b21 by Molmil
Dimer structure of murine Nectin-1 D1
分子名称: murine Nectin-1 D1
著者Sangawa, T, Takebe, K, Suzuki, M.
登録日2015-12-28
公開日2016-12-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Dimer structure of murine Nectin-1 D1
To Be Published
7YTY
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BU of 7yty by Molmil
Mouse SVCT1 in an apo state
分子名称: Solute carrier family 23 member 1
著者She, J, Wang, M, He, J, Zhang, K, Li, S.
登録日2022-08-16
公開日2023-05-03
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis of vitamin C recognition and transport by mammalian SVCT1 transporter.
Nat Commun, 14, 2023
7ZED
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BU of 7zed by Molmil
Solution structure of thanatin-like derivative 7 in complex with E.coli LptA mutant Q62L
分子名称: Lipopolysaccharide export system protein LptA, Thanatin-like derivative
著者Moehle, K, Zerbe, O.
登録日2022-03-31
公開日2023-06-07
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Peptidomimetic antibiotics disrupt the lipopolysaccharide transport bridge of drug-resistant Enterobacteriaceae.
Sci Adv, 9, 2023
5B4X
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BU of 5b4x by Molmil
Crystal structure of the ApoER2 ectodomain in complex with the Reelin R56 fragment
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Low density lipoprotein receptor-related protein 8, ...
著者Yasui, N, Hirai, H, Yamashita, K, Takagi, J, Nogi, T.
登録日2016-04-20
公開日2017-04-26
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of the ectodomain from a LDLR close homologue in complex with its physiological ligand.
To Be Published
7YPL
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BU of 7ypl by Molmil
Crystal structure of fibronectin type III domain variant, a VEGFR2-specific antagonist
分子名称: Fibronectin, SULFATE ION
著者Chang, Y.T, Chen, C.Y, Chuang, W.J.
登録日2022-08-03
公開日2023-08-16
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献A Novel Disulfide Bond Engineering of Fibronectin Type III Domain Enhances Thermostability and Solubility of VEGFR2-Specific Antagonist
To Be Published
7DBF
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BU of 7dbf by Molmil
The structure of the Arabidopsis thaliana guanosine deaminase
分子名称: Guanosine deaminase, ZINC ION
著者Xie, W, Jia, Q, Zeng, H.
登録日2020-10-20
公開日2021-09-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The C-terminal loop of Arabidopsis thaliana guanosine deaminase is essential to catalysis.
Chem.Commun.(Camb.), 57, 2021

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件を2024-08-28に公開中

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