PDB: 47120 件ウェブページステータス検索Chemie searchBIRD

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2R43	I50V HIV-1 protease in complex with an amino decorated pyrrolidine-based inhibitor 分子名称: CHLORIDE ION, GLYCEROL, N,N'-(3S,4S)-PYRROLIDINE-3,4-DIYLBIS(4-AMINO-N-BENZYLBENZENESULFONAMIDE), ... 著者 Boettcher, J, Blum, A, Heine, A, Diederich, W.E, Klebe, G. 登録日 2007-08-30 公開日 2008-09-09 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Structural and Kinetic Analysis of Pyrrolidine-Based Inhibitors of the Drug-Resistant Ile84Val Mutant of HIV-1 Protease J.Mol.Biol., 383, 2008
2QHX	Structure of Pteridine Reductase from Leishmania major complexed with a ligand 分子名称: IODIDE ION, METHYL 1-(4-{[(2,4-DIAMINOPTERIDIN-6-YL)METHYL](METHYL)AMINO}BENZOYL)PIPERIDINE-4-CARBOXYLATE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Gibellini, F, Mcluskey, K, Tulloch, L, Hunter, W.N. 登録日 2007-07-03 公開日 2007-12-25 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 Discovery of potent pteridine reductase inhibitors to guide antiparasite drug development. Proc.Natl.Acad.Sci.USA, 105, 2008
2QP3	Identification and Characterization of Two Amino Acids Critical for the Substrate Inhibition of SULT2A1 分子名称: (3Beta,5alpha)-3-Hydroxyandrostan-17-one, Bile salt sulfotransferase 著者 Hsieh, Y.C. 登録日 2007-07-23 公開日 2008-07-29 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Identification and characterization of two amino acids critical for the substrate inhibition of human dehydroepiandrosterone sulfotransferase (SULT2A1) Mol.Pharmacol., 73, 2008
2G50	The location of the allosteric amino acid binding site of muscle pyruvate kinase. 分子名称: 1,2-ETHANEDIOL, 2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ALANINE, ... 著者 Holyoak, T, Williams, R, Fenton, A.W. 登録日 2006-02-22 公開日 2006-05-09 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Differentiating a Ligand's Chemical Requirements for Allosteric Interactions from Those for Protein Binding. Phenylalanine Inhibition of Pyruvate Kinase. Biochemistry, 45, 2006
2G88	MSRECA-dATP COMPLEX 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CITRIC ACID, MAGNESIUM ION, ... 著者 Krishna, R, Manjunath, G.P, Kumar, P, Surolia, A, Chandra, N.R, Muniyappa, K, Vijayan, M. 登録日 2006-03-02 公開日 2006-05-16 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Crystallographic identification of an ordered C-terminal domain and a second nucleotide-binding site in RecA: new insights into allostery. Nucleic Acids Res., 34, 2006
2QSG	Crystal structure of Rad4-Rad23 bound to a UV-damaged DNA 分子名称: DNA repair protein RAD4, UV excision repair protein RAD23, damaged strand of the CPD-mismatch DNA, ... 著者 Min, J.-H, Pavletich, N.P. 登録日 2007-07-31 公開日 2007-10-02 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Recognition of DNA damage by the Rad4 nucleotide excision repair protein Nature, 449, 2007
2G4H	Anomalous substructure of apoferritin 分子名称: CADMIUM ION, CHLORIDE ION, Ferritin light chain 著者 Mueller-Dieckmann, C, Weiss, M.S. 登録日 2006-02-22 公開日 2007-03-06 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 On the routine use of soft X-rays in macromolecular crystallography. Part IV. Efficient determination of anomalous substructures in biomacromolecules using longer X-ray wavelengths. Acta Crystallogr.,Sect.D, 63, 2007
2QUO	Crystal Structure of C terminal fragment of Clostridium perfringens enterotoxin 分子名称: Heat-labile enterotoxin B chain, SULFATE ION 著者 Betts, L, Van Itallie, C.M. 登録日 2007-08-06 公開日 2007-10-30 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structure of the claudin-binding domain of Clostridium perfringens enterotoxin J.Biol.Chem., 283, 2008
2QVY	4-Chlorobenzoyl-CoA Ligase/Synthetase, I303G mutation, bound to 3,4-Dichlorobenzoate 分子名称: 3,4-dichlorobenzoate, 4-Chlorobenzoate CoA Ligase 著者 Wu, R, Reger, A.S, Cao, J, Gulick, A.M, Dunaway-Mariano, D. 登録日 2007-08-09 公開日 2007-12-18 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.76 Å) 主引用文献 Rational redesign of the 4-chlorobenzoate binding site of 4-chlorobenzoate: coenzyme a ligase for expanded substrate range. Biochemistry, 46, 2007
2GFK	Crystal structure of the zinc-beta-lactamase l1 from stenotrophomonas maltophilia (inhibitor 2) 分子名称: 2,5-DIPHENYLFURAN-3,4-DICARBOXYLIC ACID, DI(HYDROXYETHYL)ETHER, Metallo-beta-lactamase L1, ... 著者 Nauton, L, Garau, G, Kahn, R, Dideberg, O. 登録日 2006-03-22 公開日 2007-03-27 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural insights into the design of inhibitors for the L1 metallo-beta-lactamase from Stenotrophomonas maltophilia. J.Mol.Biol., 375, 2008
2G6K	Structure of rat nNOS heme domain (BH4 bound) complexed with NO 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, ARGININE, ... 著者 Li, H, Igarashi, J, Jamal, J, Yang, W, Poulos, T.L. 登録日 2006-02-24 公開日 2006-08-08 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural studies of constitutive nitric oxide synthases with diatomic ligands bound. J.Biol.Inorg.Chem., 11, 2006
2R20	Structure of the RNA brominated tridecamer r(GCGUU-5BUGAAACGC) at 1.3 A (Br2) 分子名称: MAGNESIUM ION, RNA (5'-R(*GP*CP*GP*UP*UP*(5BU)P*GP*AP*AP*AP*CP*GP*C)-3'), SODIUM ION 著者 Timsit, Y, Bombard, S. 登録日 2007-08-24 公開日 2007-09-25 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 The 1.3 A resolution structure of the RNA tridecamer r(GCGUUUGAAACGC): Metal ion binding correlates with base unstacking and groove contraction. Rna, 13, 2007
2KJ8	NMR structure of fragment 87-196 from the putative phage integrase IntS of E. coli: Northeast Structural Genomics Consortium target ER652A, PSI-2 分子名称: Putative prophage CPS-53 integrase 著者 Cort, J.R, Ramelot, T.A, Wang, D, Ciccosanti, C, Janjua, H, Nair, R, Rost, B, Swapna, G, Xiao, R, Everett, J.K, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) 登録日 2009-05-25 公開日 2009-07-07 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 NMR structure of fragment 87-196 from the putative phage integrase IntS of E. coli To be Published
2QBL	Crystal structure of ferric G248T cytochrome P450cam 分子名称: CAMPHOR, Cytochrome P450-cam, POTASSIUM ION, ... 著者 von Koenig, K, Makris, T.M, Sligar, S.D, Schlichting, I. 登録日 2007-06-18 公開日 2007-12-25 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Alteration of P450 Distal Pocket Solvent Leads to Impaired Proton Delivery and Changes in Heme Geometry. Biochemistry, 46, 2007
2QBN	Crystal structure of ferric G248V cytochrome P450cam 分子名称: CAMPHOR, Cytochrome P450-cam, POTASSIUM ION, ... 著者 von Koenig, K, Makris, T.M, Sligar, S.D, Schlichting, I. 登録日 2007-06-18 公開日 2007-12-25 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Alteration of P450 Distal Pocket Solvent Leads to Impaired Proton Delivery and Changes in Heme Geometry. Biochemistry, 46, 2007
2KK1	Solution structure of C-terminal Domain of Tyrosine-protein kinase ABL2 from Homo sapiens, Northeast Structural Genomics Consortium (NESG) target HR5537A 分子名称: Tyrosine-protein kinase ABL2 著者 Liu, G, Wang, D, Nwosu, C, Owens, L, Xiao, R, Liu, J, Baran, M.C, Swapna, G, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) 登録日 2009-06-14 公開日 2009-08-11 最終更新日 2024-05-08 実験手法 SOLUTION NMR 主引用文献 NMR structure of F-actin-binding domain of Arg/Abl2 from Homo sapiens. Proteins, 78, 2010
2QDQ	Crystal structure of the talin dimerisation domain 分子名称: Talin-1 著者 Gingras, A.R, Putz, N.S.M, Bate, N, Barsukov, I.L, Critchley, D.R.C. 登録日 2007-06-21 公開日 2008-01-29 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The structure of the C-terminal actin-binding domain of talin. Embo J., 27, 2008
2QFE	Distal C2-Like Domain of Human Calpain-7 分子名称: BROMIDE ION, Calpain-7 著者 Walker, J.R, Cuerrier, D, Ravulapalli, R, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S. 登録日 2007-06-27 公開日 2007-07-10 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Structure of the C2 Domain of Human Calpain-7 To be Published
2QI4	Crystal structure of protease inhibitor, MIT-2-AD93 in complex with wild type HIV-1 protease 分子名称: ACETATE ION, N-[(1S,2R)-3-{(1,3-BENZOTHIAZOL-6-YLSULFONYL)[(2S)-2-METHYLBUTYL]AMINO}-1-BENZYL-2-HYDROXYPROPYL]-3-HYDROXYBENZAMIDE, PHOSPHATE ION, ... 著者 Nalam, M.N.L, Schiffer, C.A. 登録日 2007-07-03 公開日 2008-04-22 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 HIV-1 protease inhibitors from inverse design in the substrate envelope exhibit subnanomolar binding to drug-resistant variants. J.Am.Chem.Soc., 130, 2008
2QJG	M. jannaschii ADH synthase complexed with F1,6P 分子名称: 1,6-DI-O-PHOSPHONO-D-ALLITOL, Putative aldolase MJ0400 著者 Ealick, S.E, Morar, M. 登録日 2007-07-07 公開日 2007-10-30 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid synthase, a catalyst in the archaeal pathway for the biosynthesis of aromatic amino acids. Biochemistry, 46, 2007
2QL6	human nicotinamide riboside kinase (NRK1) 分子名称: (1R)-1-[4-(AMINOCARBONYL)-1,3-THIAZOL-2-YL]-1,4-ANHYDRO-D-RIBITOL, ADENOSINE-5'-DIPHOSPHATE, nicotinamide riboside kinase 1 著者 Khan, J.A, Xiang, S, Tong, L. 登録日 2007-07-12 公開日 2007-10-02 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of human nicotinamide riboside kinase Structure, 15, 2007
2K57	Solution NMR Structure of Putative Lipoprotein from Pseudomonas syringae Gene Locus PSPTO2350. Northeast Structural Genomics Target PsR76A. 分子名称: Putative Lipoprotein 著者 Hang, D, Aramini, J.A, Rossi, P, Wang, D, Jiang, M, Maglaqui, M, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) 登録日 2008-06-25 公開日 2008-09-30 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Solution NMR Structure of Putative Lipoprotein from Pseudomonas syringae Gene Locus PSPTO2350. Northeast Structural Genomics Target PsR76A. To be Published
2QNA	Crystal structure of human Importin-beta (127-876) in complex with the IBB-domain of Snurportin1 (1-65) 分子名称: Importin subunit beta-1, SULFATE ION, Snurportin-1 著者 Wohlwend, D, Strasser, A, Dickmanns, A, Ficner, R. 登録日 2007-07-18 公開日 2008-04-08 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.84 Å) 主引用文献 Structural basis for RanGTP independent entry of spliceosomal U snRNPs into the nucleus. J.Mol.Biol., 374, 2007
2QT9	Human dipeptidyl peptidase iv/cd26 in complex with a 4-aryl cyclohexylalanine inhibitor 分子名称: (2S,3S)-3-AMINO-4-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-N,N-DIMETHYL-4-OXO-2-(TRANS-4-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-5-YLCYCLOH EXYL)BUTANAMIDE, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Scapin, G. 登録日 2007-08-01 公開日 2007-11-06 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 4-Arylcyclohexylalanine analogs as potent, selective, and orally active inhibitors of dipeptidyl peptidase IV. Bioorg.Med.Chem.Lett., 17, 2007
2KKU	Solution structure of protein af2351 from Archaeoglobus fulgidus. Northeast Structural Genomics Consortium target AtT9/Ontario Center for Structural Proteomics Target af2351 分子名称: Uncharacterized protein 著者 Wu, B, Yee, A, Fares, C, Lemak, A, Rumpel, S, Semest, A, Montelione, G.T, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG), Ontario Centre for Structural Proteomics (OCSP) 登録日 2009-06-29 公開日 2009-07-14 最終更新日 2024-05-08 実験手法 SOLUTION NMR 主引用文献 Solution structure of protein af2351 from Archaeoglobus fulgidus. Northeast Structural Genomics Consortium target AtT9/Ontario Center for Structural Proteomics Target af2351 To be Published

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