PDB: 364 件ウェブページステータス検索Chemie searchBIRD

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8ADL	Cryo-EM structure of the SEA complex 分子名称: Maintenance of telomere capping protein 5, Nitrogen permease regulator 2, Nitrogen permease regulator 3, ... 著者 Tafur, L, Loewith, R. 登録日 2022-07-08 公開日 2022-11-02 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (2.95 Å) 主引用文献 Cryo-EM structure of the SEA complex. Nature, 611, 2022
5NNY	Crystal structure of the phosphatase domain from the Legionella effector WipB 分子名称: WipB 著者 Pinotsis, N, Waksman, G, Prevost, M.S. 登録日 2017-04-10 公開日 2017-09-06 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The Legionella effector WipB is a translocated Ser/Thr phosphatase that targets the host lysosomal nutrient sensing machinery. Sci Rep, 7, 2017
6MIU	Crystal structure of p62 ZZ domain in complex with Arg-Glu peptide 分子名称: Sequestosome-1, Arg-Glu peptide chimera, ZINC ION 著者 Ahn, J, Zhang, Y, Kutateladze, T.G. 登録日 2018-09-20 公開日 2018-10-31 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 ZZ-dependent regulation of p62/SQSTM1 in autophagy. Nat Commun, 9, 2018
6MJ7	Crystal structure of p62 ZZ domain in complex with free arginine 分子名称: 1,4-DIETHYLENE DIOXIDE, ARGININE, Sequestosome-1, ... 著者 Ahn, J, Zhang, Y, Kutateladze, T.G. 登録日 2018-09-20 公開日 2018-10-31 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.412 Å) 主引用文献 ZZ-dependent regulation of p62/SQSTM1 in autophagy. Nat Commun, 9, 2018
3WDZ	Crystal Structure of Keap1 in Complex with phosphorylated p62 分子名称: Kelch-like ECH-associated protein 1, Peptide from Sequestosome-1 著者 Fukutomi, T, Takagi, K, Mizushima, T, Tanaka, K, Komatsu, M, Yamamoto, M. 登録日 2013-06-26 公開日 2013-09-04 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy. Mol.Cell, 51, 2013
6C08	Zebrafish SLC38A9 with arginine bound in the cytosol open state 分子名称: ARGININE, Sodium-coupled neutral amino acid transporter 9, antibody Fab Heavy Chain, ... 著者 Lei, H.-T, Gonen, T. 登録日 2017-12-28 公開日 2018-06-20 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (3.17 Å) 主引用文献 Crystal structure of arginine-bound lysosomal transporter SLC38A9 in the cytosol-open state. Nat. Struct. Mol. Biol., 25, 2018
2RVK	Refined solution structure of Schizosaccharomyces pombe Sin1 CRIM domain 分子名称: Stress-activated map kinase-interacting protein 1 著者 Furuita, K, Kataoka, S, Shiozaki, K, Kojima, C. 登録日 2015-12-10 公開日 2017-01-25 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Substrate specificity of TOR complex 2 is determined by a ubiquitin-fold domain of the Sin1 subunit. Elife, 6, 2017
6PW3	LARP1 DM15 FYRE (F844Y, R847E) mutant bound to m7GpppG dinucleotide (capG) 分子名称: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, La-related protein 1, MAGNESIUM ION 著者 Lahr, R.M, Berman, A.J. 登録日 2019-07-22 公開日 2019-11-06 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Capturing the Mechanism Underlying TOP mRNA Binding to LARP1. Structure, 27, 2019
6QI9	Truncated human R2TP complex, structure 4 (ADP-empty) 分子名称: ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2 著者 Munoz-Hernandez, H, Rodriguez, C.F, Llorca, O. 登録日 2019-01-18 公開日 2019-05-15 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.63 Å) 主引用文献 Structural mechanism for regulation of the AAA-ATPases RUVBL1-RUVBL2 in the R2TP co-chaperone revealed by cryo-EM. Sci Adv, 5, 2019
6QI8	Truncated human R2TP complex, structure 3 (ADP-filled) 分子名称: ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2 著者 Munoz-Hernandez, H, Rodriguez, C.F, Llorca, O. 登録日 2019-01-18 公開日 2019-04-10 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.75 Å) 主引用文献 Structural mechanism for regulation of the AAA-ATPases RUVBL1-RUVBL2 in the R2TP co-chaperone revealed by cryo-EM. Sci Adv, 5, 2019
6F34	Crystal structure of a bacterial cationic amino acid transporter (CAT) homologue bound to Arginine. 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ARGININE, Amino acid transporter, ... 著者 Jungnickel, K.E.J, Newstead, S. 登録日 2017-11-27 公開日 2018-02-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.13 Å) 主引用文献 Structural basis for amino acid transport by the CAT family of SLC7 transporters. Nat Commun, 9, 2018
6SSH	Structure of the TSC2 GAP domain 分子名称: 1,2-ETHANEDIOL, GTPase activator-like protein 著者 Hansmann, P, Kiontke, S, Kummel, D. 登録日 2019-09-06 公開日 2020-05-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structure of the TSC2 GAP Domain: Mechanistic Insight into Catalysis and Pathogenic Mutations. Structure, 28, 2020
8TXS	Solution NMR structure of designed peptide BH26 (RGVTVPHNGESKDYSV) 分子名称: BH26 peptide 著者 McShan, A.C, Torres, M.P. 登録日 2023-08-24 公開日 2023-09-06 最終更新日 2024-09-18 実験手法 SOLUTION NMR 主引用文献 Generative beta-hairpin design using a residue-based physicochemical property landscape. Biophys.J., 123, 2024
5EJC	Crystal structural of the TSC1-TBC1D7 complex 分子名称: Hamartin, TBC1 domain family member 7 著者 Wang, Z, Qin, J, Gong, W, Xu, W. 登録日 2015-11-01 公開日 2016-03-02 最終更新日 2019-11-27 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural Basis of the Interaction between Tuberous Sclerosis Complex 1 (TSC1) and Tre2-Bub2-Cdc16 Domain Family Member 7 (TBC1D7). J.Biol.Chem., 291, 2016
5OQT	Crystal structure of a bacterial cationic amino acid transporter (CAT) homologue 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ACETATE ION, ALANINE, ... 著者 Jungnickel, K.E.J, Newstead, S. 登録日 2017-08-14 公開日 2018-02-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.86 Å) 主引用文献 Structural basis for amino acid transport by the CAT family of SLC7 transporters. Nat Commun, 9, 2018
4PSI	PIH1D1/phospho-Tel2 complex 分子名称: PIH1 domain-containing protein 1, Telomere length regulation protein TEL2 homolog 著者 Smerdon, S.J, Boulton, S.J, Stach, L, Flower, T.G, Horejsi, Z. 登録日 2014-03-07 公開日 2014-04-23 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Phosphorylation-Dependent PIH1D1 Interactions Define Substrate Specificity of the R2TP Cochaperone Complex. Cell Rep, 7, 2014
4PSF	PIH1D1 N-terminal domain 分子名称: PIH1 domain-containing protein 1 著者 Smerdon, S.J, Boulton, S.J, Stach, L, Flower, T.G, Horejsi, Z. 登録日 2014-03-07 公開日 2014-04-23 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.578 Å) 主引用文献 Phosphorylation-Dependent PIH1D1 Interactions Define Substrate Specificity of the R2TP Cochaperone Complex. Cell Rep, 7, 2014
6ZEC	Crystal Structure of the Fab Fragment of a Glycosylated Lymphoma Antibody 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab fragment heavy chain, Fab fragment light chain, ... 著者 Allen, J.D, Watanabe, Y, Crispin, M, Bowden, T.A. 登録日 2020-06-16 公開日 2021-06-30 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Insertion of atypical glycans into the tumor antigen-binding site identifies DLBCLs with distinct origin and behavior. Blood, 138, 2021
6LPF	The crystal structure of human cytoplasmic LRS 分子名称: 2'-(L-NORVALYL)AMINO-2'-DEOXYADENOSINE, 5'-O-(L-leucylsulfamoyl)adenosine, GLYCEROL, ... 著者 Liu, R.J, Long, T, Li, H, Li, J, Zhao, J.H, Lin, J.Z, Palencia, A, Wang, M.Z, Cusack, S, Wang, E.D. 登録日 2020-01-10 公開日 2020-03-25 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Molecular basis of the multifaceted functions of human leucyl-tRNA synthetase in protein synthesis and beyond. Nucleic Acids Res., 48, 2020
6LR6	The crystal structure of human cytoplasmic LRS 分子名称: 4-Chloro-3-aminomethyl-7-[ethoxy]-3H-benzo[C][1,2]oxaborol-1-ol modified adenosine, 5'-O-(L-leucylsulfamoyl)adenosine, Leucine--tRNA ligase, ... 著者 Liu, R.J, Long, T, Li, H, Li, J, Zhao, J.H, Lin, J.Z, Palencia, A, Wang, M.Z, Cusack, S, Wang, E.D. 登録日 2020-01-15 公開日 2020-03-25 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.009 Å) 主引用文献 Molecular basis of the multifaceted functions of human leucyl-tRNA synthetase in protein synthesis and beyond. Nucleic Acids Res., 48, 2020
8GXP	Complex structure of RORgama with betulinic acid 分子名称: Betulinic acid, Nuclear receptor ROR-gamma 著者 Zhang, X.L, Xu, C, Bai, F. 登録日 2022-09-20 公開日 2023-06-07 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Discovery, structural optimization, and anti-tumor bioactivity evaluations of betulinic acid derivatives as a new type of ROR gamma antagonists. Eur.J.Med.Chem., 257, 2023
5HIU	Structure of the TSC2 N-terminus 分子名称: GTPase activator-like protein 著者 Zech, R, Kiontke, S, Kummel, D. 登録日 2016-01-12 公開日 2016-08-10 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of the Tuberous Sclerosis Complex 2 (TSC2) N Terminus Provides Insight into Complex Assembly and Tuberous Sclerosis Pathogenesis. J.Biol.Chem., 291, 2016
6MP6	Cryo-EM structure of the human neutral amino acid transporter ASCT2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Neutral amino acid transporter B(0) 著者 Yu, X, Han, S. 登録日 2018-10-05 公開日 2019-11-06 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (3.54 Å) 主引用文献 Cryo-EM structures of the human glutamine transporter SLC1A5 (ASCT2) in the outward-facing conformation. Elife, 8, 2019
6MPB	Cryo-EM structure of the human neutral amino acid transporter ASCT2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMINE, Neutral amino acid transporter B(0) 著者 Yu, X, Han, S. 登録日 2018-10-05 公開日 2019-11-06 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (3.84 Å) 主引用文献 Cryo-EM structures of the human glutamine transporter SLC1A5 (ASCT2) in the outward-facing conformation. Elife, 8, 2019
4F3M	Crystal structure of CRISPR-associated protein 分子名称: 1,2-ETHANEDIOL, BH0337 protein, SULFATE ION 著者 Ke, A, Nam, K.H. 登録日 2012-05-09 公開日 2012-08-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 Cas5d Protein Processes Pre-crRNA and Assembles into a Cascade-like Interference Complex in Subtype I-C/Dvulg CRISPR-Cas System. Structure, 20, 2012

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