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7RPX
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Archaeal DNA ligase and heterotrimeric PCNA in complex with end-joined DNA
分子名称: DNA ligase, DNA polymerase sliding clamp 1, DNA polymerase sliding clamp 2, ...
著者Sverzhinsky, A, Pascal, J.M.
登録日2021-08-04
公開日2021-11-17
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Cryo-EM structures and biochemical insights into heterotrimeric PCNA regulation of DNA ligase.
Structure, 30, 2022
1CZD
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BU of 1czd by Molmil
CRYSTAL STRUCTURE OF THE PROCESSIVITY CLAMP GP45 FROM BACTERIOPHAGE T4
分子名称: DNA POLYMERASE ACCESSORY PROTEIN G45
著者Moarefi, I, Jeruzalmi, D, Turner, J, O'Donnell, M, Kuriyan, J.
登録日1999-09-02
公開日2000-03-03
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Crystal structure of the DNA polymerase processivity factor of T4 bacteriophage.
J.Mol.Biol., 296, 2000
5KL1
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BU of 5kl1 by Molmil
Crystal structure of the Pumilio-Nos-hunchback RNA complex
分子名称: Maternal protein pumilio, Protein nanos, RNA (5'-R(*AP*AP*AP*UP*UP*GP*UP*AP*CP*AP*UP*A)-3'), ...
著者Qiu, C, Hall, T.M.T.
登録日2016-06-23
公開日2016-08-17
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.701 Å)
主引用文献Drosophila Nanos acts as a molecular clamp that modulates the RNA-binding and repression activities of Pumilio.
Elife, 5, 2016
2HII
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BU of 2hii by Molmil
heterotrimeric PCNA sliding clamp
分子名称: PCNA1 (SSO0397), PCNA2 (SSO1047), PCNA3 (SSO0405)
著者Pascal, J.M, Tsodikov, O.V, Ellenberger, T.
登録日2006-06-29
公開日2006-11-07
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献A Flexible Interface between DNA Ligase and PCNA Supports Conformational Switching and Efficient Ligation of DNA.
Mol.Cell, 24, 2006
2HIK
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BU of 2hik by Molmil
heterotrimeric PCNA sliding clamp
分子名称: PCNA1 (SSO0397), PCNA2 (SSO1047), PCNA3 (SSO0405)
著者Pascal, J.M, Tsodikov, O.V, Ellenberger, T.
登録日2006-06-29
公開日2006-11-07
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献A Flexible Interface between DNA Ligase and PCNA Supports Conformational Switching and Efficient Ligation of DNA.
Mol.Cell, 24, 2006
2IO4
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BU of 2io4 by Molmil
Crystal structure of PCNA12 dimer from Sulfolobus solfataricus.
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, DNA polymerase sliding clamp B, ...
著者Hlinkova, V, Ling, H.
登録日2006-10-09
公開日2008-04-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structures of monomeric, dimeric and trimeric PCNA: PCNA-ring assembly and opening.
Acta Crystallogr.,Sect.D, 64, 2008
2NTI
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BU of 2nti by Molmil
Crystal structure of PCNA123 heterotrimer.
分子名称: 2,5,8,11,14,17,20,23-OCTAOXAPENTACOSAN-25-OL, BROMIDE ION, DNA polymerase sliding clamp A, ...
著者Hlinkova, V, Ling, H.
登録日2006-11-07
公開日2007-12-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures of monomeric, dimeric and trimeric PCNA: PCNA-ring assembly and opening.
Acta Crystallogr.,Sect.D, 64, 2008
2IZO
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BU of 2izo by Molmil
Structure of an Archaeal PCNA1-PCNA2-FEN1 Complex
分子名称: DNA POLYMERASE SLIDING CLAMP B, DNA POLYMERASE SLIDING CLAMP C, FLAP STRUCTURE-SPECIFIC ENDONUCLEASE, ...
著者Dore, A.S, Kilkenny, M.L, Roe, S.M, Pearl, L.H.
登録日2006-07-25
公開日2006-09-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of an Archaeal PCNA1-PCNA2-Fen1 Complex: Elucidating PCNA Subunit and Client Enzyme Specificity.
Nucleic Acids Res., 34, 2006
4MJR
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BU of 4mjr by Molmil
E. coli sliding clamp in complex with (S)-Carprofen
分子名称: (2S)-2-(6-chloro-9H-carbazol-2-yl)propanoic acid, CALCIUM ION, CHLORIDE ION, ...
著者Yin, Z, Oakley, A.J.
登録日2013-09-04
公開日2013-09-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献DNA replication is the target for the antibacterial effects of nonsteroidal anti-inflammatory drugs.
Chem.Biol., 21, 2014
4MJP
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BU of 4mjp by Molmil
E. coli sliding clamp in complex with (R)-Vedaprofen
分子名称: (2R)-2-(4-cyclohexylnaphthalen-1-yl)propanoic acid, CALCIUM ION, CHLORIDE ION, ...
著者Yin, Z, Oakley, A.J.
登録日2013-09-04
公開日2013-09-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.855 Å)
主引用文献DNA replication is the target for the antibacterial effects of nonsteroidal anti-inflammatory drugs.
Chem.Biol., 21, 2014
4MJQ
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BU of 4mjq by Molmil
E. coli sliding clamp in complex with Bromfenac
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ...
著者Yin, Z, Oakley, A.J.
登録日2013-09-04
公開日2013-09-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献DNA replication is the target for the antibacterial effects of nonsteroidal anti-inflammatory drugs.
Chem.Biol., 21, 2014
2IX2
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BU of 2ix2 by Molmil
Crystal structure of the heterotrimeric PCNA from Sulfolobus solfataricus
分子名称: DNA POLYMERASE SLIDING CLAMP A, DNA POLYMERASE SLIDING CLAMP B, DNA POLYMERASE SLIDING CLAMP C
著者Williams, G.J, Johnson, K, McMahon, S.A, Carter, L, Oke, M, Liu, H, Taylor, G.L, White, M.F, Naismith, J.H.
登録日2006-07-05
公開日2006-10-04
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the Heterotrimeric PCNA from Sulfolobus Solfataricus.
Acta Crystallogr.,Sect.F, 62, 2006
2IJX
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BU of 2ijx by Molmil
Crystal structure of PCNA3 monomer from Sulfolobus solfataricus.
分子名称: 1,2-ETHANEDIOL, DNA polymerase sliding clamp A
著者Hlinkova, V, Ling, H.
登録日2006-10-01
公開日2007-10-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures of monomeric, dimeric and trimeric PCNA: PCNA-ring assembly and opening.
Acta Crystallogr.,Sect.D, 64, 2008
5TJG
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BU of 5tjg by Molmil
Thermus aquaticus delta1.1-sigmaA holoenzyme/downstream-fork promoter complex with an open clamp
分子名称: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*A)-3'), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Darst, S.A, Bae, B.
登録日2016-10-04
公開日2017-06-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献RNA polymerase motions during promoter melting.
Science, 356, 2017
3AIX
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BU of 3aix by Molmil
Crystal structure of PCNA2-PCNA3 complex from Sulfolobus tokodaii (I222)
分子名称: DNA polymerase sliding clamp B, DNA polymerase sliding clamp C, SULFATE ION
著者Kawai, A, Higuchi, S, Miyamoto, S.
登録日2010-05-18
公開日2011-05-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A novel heterotetrameric structure of the crenarchaeal PCNA2-PCNA3 complex
J.Struct.Biol., 174, 2011
3AIZ
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BU of 3aiz by Molmil
Crystal structure of PCNA2-PCNA3 complex from Sulfolobus tokodaii (P21212)
分子名称: DNA polymerase sliding clamp B, DNA polymerase sliding clamp C, SULFATE ION
著者Kawai, A, Higuchi, S, Miyamoto, S.
登録日2010-05-18
公開日2011-05-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A novel heterotetrameric structure of the crenarchaeal PCNA2-PCNA3 complex
J.Struct.Biol., 174, 2011
8UI8
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BU of 8ui8 by Molmil
Cryo-EM map of human clamp-clamp loader ATAD5-RFC-two PCNAs complex in intermediate state 3
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATPase family AAA domain-containing protein 5, MAGNESIUM ION, ...
著者Wang, F, He, Q, Li, H.
登録日2023-10-10
公開日2024-05-29
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献The human ATAD5 has evolved unique structural elements to function exclusively as a PCNA unloader.
Nat.Struct.Mol.Biol., 2024
8UI9
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BU of 8ui9 by Molmil
Cryo-EM map of human clamp-clamp loader ATAD5-RFC-cracked PCNA complex in intermediate state 2
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATPase family AAA domain-containing protein 5, MAGNESIUM ION, ...
著者Wang, F, He, Q, Li, H.
登録日2023-10-10
公開日2024-05-29
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献The human ATAD5 has evolved unique structural elements to function exclusively as a PCNA unloader.
Nat.Struct.Mol.Biol., 2024
8UII
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BU of 8uii by Molmil
Cryo-EM map of human clamp-clamp loader ATAD5-RFC-closed PCNA complex in intermediate state 1
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATPase family AAA domain-containing protein 5, MAGNESIUM ION, ...
著者Wang, F, He, Q, Li, H.
登録日2023-10-10
公開日2024-05-29
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.04 Å)
主引用文献The human ATAD5 has evolved unique structural elements to function exclusively as a PCNA unloader.
Nat.Struct.Mol.Biol., 2024
5AGU
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BU of 5agu by Molmil
The sliding clamp of Mycobacterium tuberculosis in complex with a natural product.
分子名称: (R,R)-2,3-BUTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA POLYMERASE III SUBUNIT BETA, ...
著者Lukat, P, Kling, A, Heinz, D.W, Mueller, R.
登録日2015-02-03
公開日2015-06-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.173 Å)
主引用文献Antibiotics. Targeting Dnan for Tuberculosis Therapy Using Novel Griselimycins.
Science, 348, 2015
5AGV
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BU of 5agv by Molmil
The sliding clamp of Mycobacterium tuberculosis in complex with a natural product.
分子名称: (R,R)-2,3-BUTANEDIOL, CALCIUM ION, CYCLOHEXYL GRISELIMYCIN, ...
著者Lukat, P, Kling, A, Heinz, D.W, Mueller, R.
登録日2015-02-03
公開日2015-06-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Antibiotics. Targeting Dnan for Tuberculosis Therapy Using Novel Griselimycins.
Science, 348, 2015
3Q4J
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BU of 3q4j by Molmil
Structure of a small peptide ligand bound to E.coli DNA sliding clamp
分子名称: DNA polymerase III subunit beta, peptide ligand
著者Wolff, P, Olieric, V, Briand, J.P, Chaloin, O, Dejaegere, A, Dumas, P, Ennifar, E, Guichard, G, Wagner, J, Burnouf, D.
登録日2010-12-23
公開日2011-12-28
最終更新日2013-03-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure-based design of short peptide ligands binding onto the E. coli processivity ring.
J.Med.Chem., 54, 2011
1YYP
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BU of 1yyp by Molmil
Crystal structure of cytomegalovirus UL44 bound to C-terminal peptide from CMV UL54
分子名称: 1,2-ETHANEDIOL, DNA polymerase, DNA polymerase processivity factor, ...
著者Appleton, B.A, Brooks, J, Loregian, A, Filman, D.J, Coen, D.M, Hogle, J.M.
登録日2005-02-25
公開日2005-12-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of the cytomegalovirus DNA polymerase subunit UL44 in complex with the C terminus from the catalytic subunit. Differences in structure and function relative to unliganded UL44.
J.Biol.Chem., 281, 2006
7TFI
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BU of 7tfi by Molmil
Atomic model of the S. cerevisiae clamp-clamp loader complex PCNA-RFC bound to DNA with an open clamp
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
著者Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H.
登録日2022-01-06
公開日2022-11-16
実験手法ELECTRON MICROSCOPY (3.41 Å)
主引用文献Cryo-EM structures reveal that RFC recognizes both the 3'- and 5'-DNA ends to load PCNA onto gaps for DNA repair.
Elife, 11, 2022
7TFJ
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BU of 7tfj by Molmil
Atomic model of S. cerevisiae clamp-clamp loader complex PCNA-RFC bound to DNA with a closed clamp ring
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
著者Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H.
登録日2022-01-06
公開日2022-11-16
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structures reveal that RFC recognizes both the 3'- and 5'-DNA ends to load PCNA onto gaps for DNA repair.
Elife, 11, 2022

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