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7FGQ
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BU of 7fgq by Molmil
Crystal structure of Thymidylate kinase with TMP and its low-resolution (SAXS) solution structure from Brugia malayi
分子名称: THYMIDINE-5'-PHOSPHATE, dTMP kinase
著者Ramachandran, R, Vishwakarma, J, Sharma, V.K.
登録日2021-07-27
公開日2022-07-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Crystal structure of Thymidylate kinase with TMP and its low-resolution (SAXS) solution structure from Brugia malayi
To Be Published
3B3P
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BU of 3b3p by Molmil
Structure of neuronal nos heme domain in complex with a inhibitor (+-)-n1-{cis-4'-[(6"-amino-4"-methylpyridin-2"-yl)methyl]pyrrolidin-3'-yl}-n2-(4'-chlorobenzyl)ethane-1,2-diamine
分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, N-{(3R,4S)-4-[(6-amino-4-methylpyridin-2-yl)methyl]pyrrolidin-3-yl}-N'-(3-chlorobenzyl)ethane-1,2-diamine, ...
著者Igarashi, J, Li, H, Poulos, T.L.
登録日2007-10-22
公開日2008-11-04
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Crystal structures of constitutive nitric oxide synthases in complex with de novo designed inhibitors.
J.Med.Chem., 52, 2009
7EVN
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BU of 7evn by Molmil
The cryo-EM structure of the DDX42-SF3b complex
分子名称: ATP-dependent RNA helicase DDX42, PHD finger-like domain-containing protein 5A, Splicing factor 3B subunit 1, ...
著者Zhang, X, Zhan, X, Shi, Y.
登録日2021-05-21
公開日2022-08-03
最終更新日2024-01-17
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural insights into branch site proofreading by human spliceosome
Nat.Struct.Mol.Biol., 2024
7FB9
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BU of 7fb9 by Molmil
Crystal Structure of Human Cu, Zn Superoxide Dismutase (SOD1)
分子名称: COPPER (II) ION, Superoxide dismutase [Cu-Zn], ZINC ION
著者Baek, Y, Ha, N.-C.
登録日2021-07-08
公開日2022-10-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural analysis of the overoxidized Cu/Zn-superoxide dismutase in ROS-induced ALS filament formation.
Commun Biol, 5, 2022
7FDY
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BU of 7fdy by Molmil
Structure of OmpF1
分子名称: Porin OmpF, ZINC ION
著者Jeong, W.J, Song, W.J.
登録日2021-07-18
公開日2022-11-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Design and directed evolution of noncanonical beta-stereoselective metalloglycosidases.
Nat Commun, 13, 2022
2JMX
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BU of 2jmx by Molmil
OSCP-NT (1-120) in complex with N-terminal (1-25) alpha subunit from F1-ATPase
分子名称: ATP synthase O subunit, mitochondrial, ATP synthase subunit alpha heart isoform
著者Carbajo, R.J, Neuhaus, D, Kellas, F.A, Yang, J, Runswick, M.J, Montgomery, M.G, Walker, J.E.
登録日2006-12-12
公開日2007-04-24
最終更新日2023-12-20
実験手法SOLUTION NMR
主引用文献How the N-terminal Domain of the OSCP Subunit of Bovine F(1)F(o)-ATP Synthase Interacts with the N-terminal Region of an Alpha Subunit
J.Mol.Biol., 368, 2007
2PSQ
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BU of 2psq by Molmil
Crystal Structure of Unphosphorylated Unactivated Wild Type FGF Receptor 2 (FGFR2) Kinase Domain
分子名称: Fibroblast growth factor receptor 2, SULFATE ION
著者Chen, H, Mohammadi, M.
登録日2007-05-07
公開日2007-09-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases.
Mol.Cell, 27, 2007
3B78
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Structure of the eEF2-ExoA(R551H)-NAD+ complex
分子名称: Elongation factor 2, Exotoxin A, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Jorgensen, R, Merrill, A.R.
登録日2007-10-30
公開日2008-06-17
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The nature and character of the transition state for the ADP-ribosyltransferase reaction.
Embo Rep., 9, 2008
3B97
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Crystal Structure of human Enolase 1
分子名称: Alpha-enolase, MAGNESIUM ION, SULFATE ION
著者Kang, H.J, Jung, S.K, Kim, S.J, Chung, S.J.
登録日2007-11-02
公開日2008-09-16
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of human alpha-enolase (hENO1), a multifunctional glycolytic enzyme.
Acta Crystallogr.,Sect.D, 64, 2008
3BA1
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BU of 3ba1 by Molmil
Structure of hydroxyphenylpyruvate reductase from coleus blumei
分子名称: Hydroxyphenylpyruvate reductase
著者Janiak, V, Klebe, G, Petersen, M, Heine, A.
登録日2007-11-07
公開日2008-11-11
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Structure and substrate docking of a hydroxy(phenyl)pyruvate reductase from the higher plant Coleus blumei Benth.
Acta Crystallogr.,Sect.D, 66, 2010
2PVK
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BU of 2pvk by Molmil
Structure-Based Design of Pyrazolo[1,5-a][1,3,5]triazine Derivatives as Potent Inhibitors of Protein Kinase CK2
分子名称: 2-(4-CHLOROBENZYLAMINO)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE, Casein kinase II subunit alpha
著者Nie, Z, Perretta, C, Erickson, P, Margosiak, S, Almassy, R, Lu, J, Averill, A, Yager, K.M, Chu, S.
登録日2007-05-09
公開日2008-05-13
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure-based design, synthesis, and study of pyrazolo[1,5-a][1,3,5]triazine derivatives as potent inhibitors of protein kinase CK2.
Bioorg.Med.Chem.Lett., 17, 2007
3KLE
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BU of 3kle by Molmil
Crystal structure of AZT-resistant HIV-1 Reverse Transcriptase crosslinked to a DSDNA with a bound excision product, AZTPPPPA
分子名称: DNA (25-MER), DNA (5'-D(*AP*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*(MRG)P*CP*GP*CP*CP*(2DA))-3'), GLYCEROL, ...
著者Tu, X, Das, K, Sarafianos, S.G, Arnold, E.
登録日2009-11-07
公開日2010-09-22
最終更新日2021-10-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis of HIV-1 resistance to AZT by excision.
Nat.Struct.Mol.Biol., 17, 2010
2PVY
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BU of 2pvy by Molmil
Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic K659N Mutation Responsible for an Unclassified Craniosynostosis Syndrome.
分子名称: Fibroblast growth factor receptor 2, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, SULFATE ION
著者Chen, H, Mohammadi, M.
登録日2007-05-10
公開日2007-09-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases.
Mol.Cell, 27, 2007
7FCV
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BU of 7fcv by Molmil
Cryo-EM structure of the Potassium channel AKT1 mutant from Arabidopsis thaliana
分子名称: PHOSPHATIDYLETHANOLAMINE, POTASSIUM ION, Potassium channel AKT1
著者Yang, G.H, Lu, Y.M, Jia, Y.T, Zhang, Y.M, Tang, R.F, Xu, X, Li, X.M, Lei, J.L.
登録日2021-07-15
公開日2022-11-09
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis for the activity regulation of a potassium channel AKT1 from Arabidopsis.
Nat Commun, 13, 2022
2JRR
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BU of 2jrr by Molmil
Solution NMR Structure of Q5LLS5 from Silicibacter pomeroyi. Northeast Structural Genomics Consortium target SiR90
分子名称: Uncharacterized protein
著者Swapna, G.V.T, Tejero, R, Jiang, M, Cunningham, K, Maglaqui, M, Owens, L, Liu, J, Wang, H, Acton, T.B, Xiao, R, Baran, M.C, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2007-06-28
公開日2007-07-17
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Solution NMR Structure of Q5LLS5 from Silicibacter pomeroyi.
To be Published
2JNT
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BU of 2jnt by Molmil
Structure of Bombyx mori Chemosensory Protein 1 in Solution
分子名称: Chemosensory protein CSP1
著者Jansen, S, Zidek, L, Chmelik, J, Novak, P, Padrta, P, Picimbon, J, Lofstedt, C, Sklenar, V.
登録日2007-02-02
公開日2007-11-20
最終更新日2023-12-20
実験手法SOLUTION NMR
主引用文献Structure of Bombyx mori chemosensory protein 1 in solution
Arch.Insect Biochem.Physiol., 66, 2007
3KNQ
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BU of 3knq by Molmil
Beta Turn Optimization of the Gene-3-Protein of Filamentous Phage Fd
分子名称: Attachment protein G3P
著者Jakob, R.P, Dobbek, H.
登録日2009-11-12
公開日2009-11-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Elimination of a cis-proline-containing loop and turn optimization stabilizes a protein and accelerates its folding.
J.Mol.Biol., 399, 2010
7EWH
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BU of 7ewh by Molmil
Crystal structure of human PHGDH in complex with Homoharringtonine
分子名称: (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, D-3-phosphoglycerate dehydrogenase
著者Hsieh, C.H, Cheng, Y.S, Lee, Y.S, Huang, H.C, Juan, H.F.
登録日2021-05-25
公開日2022-12-07
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献Homoharringtonine as a PHGDH inhibitor: Unraveling metabolic dependencies and developing a potent therapeutic strategy for high-risk neuroblastoma.
Biomed Pharmacother, 166, 2023
2PZR
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BU of 2pzr by Molmil
Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic K641R Mutation Responsible for Pfeiffer Syndrome
分子名称: Fibroblast growth factor receptor 2, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, SULFATE ION
著者Chen, H, Mohammadi, M.
登録日2007-05-18
公開日2007-09-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases.
Mol.Cell, 27, 2007
3KP2
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BU of 3kp2 by Molmil
Staphylococcus epidermidis TcaR in complex with penicillin G
分子名称: CACODYLATE ION, PENICILLIN G, Transcriptional regulator TcaR
著者Chang, Y.M, Chen, C.K, Wang, A.H.
登録日2009-11-15
公開日2010-06-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural study of TcaR and its complexes with multiple antibiotics from Staphylococcus epidermidis.
Proc.Natl.Acad.Sci.USA, 107, 2010
3BFP
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BU of 3bfp by Molmil
Crystal Structure of apo-PglD from Campylobacter jejuni
分子名称: Acetyltransferase, CITRATE ANION
著者Rangarajan, E.S, Watson, D.C, Leclerc, S, Proteau, A, Cygler, M, Matte, A, Young, N.M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
登録日2007-11-22
公開日2008-01-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structure and Active Site Residues of PglD, an N-Acetyltransferase from the Bacillosamine Synthetic Pathway Required for N-Glycan Synthesis in Campylobacter jejuni.
Biochemistry, 47, 2008
3KPF
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BU of 3kpf by Molmil
X-ray structure of the mutant Lys300Met of polyamine oxidase from Zea mays
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ...
著者Fiorillo, A, Ilari, A, Tavladoraki, P.
登録日2009-11-16
公開日2010-11-17
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The crystal structure of the mutant K300M of polyamine oxidase from ZEA MAYS unveils the role of LYS300 in catalysis
To be Published
7JGL
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BU of 7jgl by Molmil
Crystal Structure of the Zn-bound Human Heavy-chain variant 122H-delta C-star with 2,5-furandihyrdoxamate collected at 100K
分子名称: Ferritin heavy chain, N~2~,N~5~-dihydroxyfuran-2,5-dicarboxamide, SODIUM ION, ...
著者Bailey, J.B, Tezcan, F.A.
登録日2020-07-19
公開日2020-10-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Tunable and Cooperative Thermomechanical Properties of Protein-Metal-Organic Frameworks.
J.Am.Chem.Soc., 142, 2020
7JIB
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Room Temperature Crystal Structure of Nsp10/Nsp16 from SARS-CoV-2 with Substrates and Products of 2'-O-methylation of the Cap-1
分子名称: 2'-O-methyltransferase, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-(2'-O-METHYL)-ADENOSINE, ...
著者Wilamowski, M, Minasov, G, Kim, Y, Sherrell, D.A, Shuvalova, L, Lavens, A, Chard, R, Rosas-Lemus, M, Maltseva, N, Jedrzejczak, R, Michalska, K, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2020-07-23
公開日2020-08-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献2'-O methylation of RNA cap in SARS-CoV-2 captured by serial crystallography.
Proc.Natl.Acad.Sci.USA, 118, 2021
3BGZ
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Human Pim-1 kinase in complex with diphenyl indole inhibitor VX3
分子名称: 2,3-diphenyl-1H-indole-7-carboxylic acid, Proto-oncogene serine/threonine-protein kinase Pim-1
著者Jacobs, M.D.
登録日2007-11-27
公開日2007-12-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Docking study yields four novel inhibitors of the protooncogene pim-1 kinase.
J.Med.Chem., 51, 2008

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