PDB: 37932 件ウェブページステータス検索Chemie searchBIRD

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7DPO	Crystal Structure of BRD2(BD2)with Ligand ZB-BD-224 bound 分子名称: 5-(1-naphthoyl)-11-methyl-8-((methylsulfonyl)methyl)-4,5-dihydro-2,3a1,5-triazadibenzo[cd,h]azulen-1(2H)-one, Bromodomain-containing protein 2 著者 Li, Z, Lu, T, Chen, P, Luo, C, Zhou, B. 登録日 2020-12-21 公開日 2021-12-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.29994035 Å) 主引用文献 Structure Base Design of A new chemotype of Four-Cycle Compounds as Bromodomain and Extra-Terminal (BET) Inhibitors with The Second Bromodomain Bias and Highly Anti-inflammatory Potency To Be Published
7DON	Structure of tubulin H392D mutant from Odinarchaeota 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Robinson, R.C, Akil, C. 登録日 2020-12-14 公開日 2021-12-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of tubulin H392D mutant from Odinarchaeota To Be Published
7DPN	Crystal structure of BRD2(BD1)with ligand ZB-BD-224 bound 分子名称: 5-(1-naphthoyl)-11-methyl-8-((methylsulfonyl)methyl)-4,5-dihydro-2,3a1,5-triazadibenzo[cd,h]azulen-1(2H)-one, Bromodomain-containing protein 2 著者 Li, Z, Lu, T, Chen, P, Luo, C, Zhou, B. 登録日 2020-12-20 公開日 2021-12-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.79998839 Å) 主引用文献 Structure Base Design of A new chemotype of Four-Cycle Compounds as Bromodomain and Extra-Terminal (BET) Inhibitors with The Second Bromodomain Bias and Highly Anti-inflammatory Potency To Be Published
8UUK	Pendrin in apo 分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, CHOLESTEROL, Lauryl Maltose Neopentyl Glycol, ... 著者 Wang, L, Hoang, A, Zhou, M. 登録日 2023-11-01 公開日 2024-02-07 最終更新日 2024-02-28 実験手法 ELECTRON MICROSCOPY (2.5 Å) 主引用文献 Mechanism of anion exchange and small-molecule inhibition of pendrin. Nat Commun, 15, 2024
8IN9	The structure of the GfsA KSQ-AT didomain in complex with the GfsA ACP domain 分子名称: N-[2-(acetylamino)ethyl]-N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alaninamide, Polyketide synthase 著者 Chisuga, T, Murakami, S, Miyanaga, A, Kudo, F, Eguchi, T. 登録日 2023-03-09 公開日 2023-05-31 最終更新日 2023-06-28 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Structure-Based Analysis of Transient Interactions between Ketosynthase-like Decarboxylase and Acyl Carrier Protein in a Loading Module of Modular Polyketide Synthase. Acs Chem.Biol., 18, 2023
8G1H	Ancestral protein AncTh of Phosphomethylpirimidine kinases family 分子名称: 1,2-ETHANEDIOL, PHOSPHATE ION, Phosphomethylpyrimidine Kinase 著者 Perez, M, Munoz, S, Cea, P, Castro-Fernandez, V. 登録日 2023-02-02 公開日 2024-02-07 最終更新日 2024-08-21 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Deciphering Structural Traits for Thermal and Kinetic Stability across Protein Family Evolution through Ancestral Sequence Reconstruction. Mol.Biol.Evol., 41, 2024
7DSG	Crystal structure of Brucella abortus PhiA 分子名称: Brucella Abortus PhiA 著者 Hyun, Y, Ha, N.-C. 登録日 2020-12-31 公開日 2022-01-12 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of Brucella abortus PhiA To Be Published
8IEV	Crystal structure of the DUF2891 family protein CJ0554 from Campylobacter jejuni in space group C2 分子名称: DUF2891 domain-containing protein 著者 Kim, S.Y, Cho, H.Y, Yoon, S.I. 登録日 2023-02-16 公開日 2023-05-31 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Unique dimeric structure of the DUF2891 family protein CJ0554 from Campylobacter jejuni. Biochem.Biophys.Res.Commun., 655, 2023
8G2N	Crystal structure of Tetrahymena thermophila G-rich DNA with novel ligand PyDH2 分子名称: 4,4'-{pyridine-2,6-diylbis[carbonyl-(1E)-hydrazin-2-yl-1-ylidene-(E)-methanylylidene]}bis(1-methylquinolin-1-ium), G-rich DNA, MAGNESIUM ION, ... 著者 Martin, K.N, Yatsunyk, L.A. 登録日 2023-02-06 公開日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.33 Å) 主引用文献 Crystal structure of Tetrahymena thermophila G-rich DNA with novel ligand PyDH2 To be published
8IEU	Crystal structure of the DUF2891 family protein CJ0554 from Campylobacter jejuni in space group P41212 分子名称: DUF2891 domain-containing protein 著者 Kim, S.Y, Cho, H.Y, Yoon, S.I. 登録日 2023-02-16 公開日 2023-05-31 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Unique dimeric structure of the DUF2891 family protein CJ0554 from Campylobacter jejuni. Biochem.Biophys.Res.Commun., 655, 2023
7DT9	D30N HIV Protease in complex with Saquinavir 分子名称: (2S)-N-[(2S,3R)-4-[(2S,3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1 -phenyl-butan-2-yl]-2-(quinolin-2-ylcarbonylamino)butanediamide, Protease 著者 Bihani, S.C, Hosur, M.V. 登録日 2021-01-04 公開日 2022-01-12 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 D30N HIV Protease in complex with Saquinavir To Be Published
7DT1	The structure of Lactobacillus fermentum 4,6-alpha-Glucanotransferase 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... 著者 Yang, W.K, Yong, Y.H, Wu, L, Chen, S, Zhou, J.H, Wu, J. 登録日 2021-01-04 公開日 2022-01-12 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.43002272 Å) 主引用文献 Characterization of a new 4,6-alpha-glucanotransferase from Limosilactobacillus fermentum NCC 3057 with ability of synthesizing low molecular mass isomalto-/maltopolysaccharide Food Biosci, 46, 2022
8IOU	Structure of SARS-CoV-2 XBB.1 spike glycoprotein in complex with ACE2 (1-up state) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... 著者 Anraku, Y, Kita, S, Yajima, H, Sasaki, J, Sasaki-Tabata, K, Maenaka, K, Hashiguchi, T. 登録日 2023-03-13 公開日 2023-05-24 最終更新日 2023-07-19 実験手法 ELECTRON MICROSCOPY (3.18 Å) 主引用文献 Virological characteristics of the SARS-CoV-2 XBB variant derived from recombination of two Omicron subvariants. Nat Commun, 14, 2023
8G8R	RelB NLS in complex with Importin alpha 2 分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Importin subunit alpha-1, Transcription factor RelB 著者 Tsimbslyuk, S, Stewart, M, Forwood, J.K. 登録日 2023-02-19 公開日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 monopartite p52 NLS in complex with Importin alpha 2 To Be Published
8G8S	bipartite p52 NLS in complex with Importin alpha 2 分子名称: Importin subunit alpha-1, Nuclear factor NF-kappa-B p100 subunit isoform X1 著者 Tsimbslyuk, S, Stewart, M, Forwood, J.K. 登録日 2023-02-19 公開日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 p52 bipartite NLS in complex with Importin alpha 2 To Be Published
8VDA	Crystal structure of Bacillus subtilis FabHA-coenzyme A complex 分子名称: Beta-ketoacyl-[acyl-carrier-protein] synthase III 1, COENZYME A 著者 Radka, C.D, Rock, C.O. 登録日 2023-12-14 公開日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Crystal structures of the fatty acid biosynthesis initiation enzymes in Bacillus subtilis. J.Struct.Biol., 216, 2024
8IOS	Structure of the SARS-CoV-2 XBB.1 spike glycoprotein (closed-1 state) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein 著者 Anraku, Y, Kita, S, Yajima, H, Sasaki, J, Sasaki-Tabata, K, Maenaka, K, Hashiguchi, T. 登録日 2023-03-13 公開日 2023-05-24 最終更新日 2023-07-19 実験手法 ELECTRON MICROSCOPY (2.5 Å) 主引用文献 Virological characteristics of the SARS-CoV-2 XBB variant derived from recombination of two Omicron subvariants. Nat Commun, 14, 2023
8G8Q	RelB NLS in complex with Importin alpha 2 分子名称: Importin subunit alpha-1, bacterial peptide, monopartite p52 NLS 著者 Tsimbslyuk, S, Stewart, M, Forwood, J.K. 登録日 2023-02-19 公開日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 p52 monopartite NLS in complex with Importin alpha 2 To Be Published
8UQP	Escherichia coli transcription-translation coupled complex class B (TTC-B) containing RfaH bound to ops signal, mRNA with a 24 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... 著者 Molodtsov, V, Wang, C, Ebright, R.H. 登録日 2023-10-24 公開日 2024-05-29 最終更新日 2024-08-28 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structural basis of RfaH-mediated transcription-translation coupling. Nat.Struct.Mol.Biol., 2024
8IM8	Crystal structure of Periplasmic alpha-amylase (MalS) from E.coli 分子名称: CALCIUM ION, Periplasmic alpha-amylase 著者 An, Y, Park, J.T, Park, K.H, Woo, E.J. 登録日 2023-03-06 公開日 2023-05-24 最終更新日 2023-06-14 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The Distinctive Permutated Domain Structure of Periplasmic alpha-Amylase (MalS) from Glycoside Hydrolase Family 13 Subfamily 19. Molecules, 28, 2023
8G8J	Crystal structure of human DNA polymerase eta incorporating ITP across dT 分子名称: CALCIUM ION, DNA (5'-D(*AP*GP*TP*GP*TP*GP*AP*G)-3'), DNA (5'-D(P*AP*TP*TP*CP*TP*CP*AP*CP*AP*CP*T)-3'), ... 著者 Jung, H. 登録日 2023-02-17 公開日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Crystal structure of human DNA polymerase eta incorporating ITP across dT To Be Published
8IOV	Structure of SARS-CoV-2 XBB.1 spike RBD in complex with ACE2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... 著者 Anraku, Y, Kita, S, Yajima, H, Sasaki, J, Sasaki-Tabata, K, Maenaka, K, Hashiguchi, T. 登録日 2023-03-13 公開日 2023-05-24 最終更新日 2023-07-19 実験手法 ELECTRON MICROSCOPY (3.29 Å) 主引用文献 Virological characteristics of the SARS-CoV-2 XBB variant derived from recombination of two Omicron subvariants. Nat Commun, 14, 2023
8GBF	Crystal structure of human DNA polymerase eta incorporating syn-ITP across dT 分子名称: CALCIUM ION, DNA (5'-D(*AP*GP*TP*GP*TP*GP*AP*G)-3'), DNA (5'-D(P*AP*TP*TP*CP*TP*CP*AP*CP*AP*CP*T)-3'), ... 著者 Jung, H. 登録日 2023-02-25 公開日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Crystal structure of human DNA polymerase eta incorporating syn-ITP across dT To Be Published
8IOT	Structure of the SARS-CoV-2 XBB.1 spike glycoprotein (closed-2 state) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein 著者 Anraku, Y, Kita, S, Yajima, H, Sasaki, J, Sasaki-Tabata, K, Maenaka, K, Hashiguchi, T. 登録日 2023-03-13 公開日 2023-05-24 最終更新日 2023-07-19 実験手法 ELECTRON MICROSCOPY (2.51 Å) 主引用文献 Virological characteristics of the SARS-CoV-2 XBB variant derived from recombination of two Omicron subvariants. Nat Commun, 14, 2023
8UOA	Structure of the synaptic vesicle protein 2A Luminal domain in complex with a nanobody 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody, Synaptic vesicle glycoprotein 2A, ... 著者 Mittal, A, Martin, M.F, Levin, E, Adams, C, Yang, M, Ledecq, M, Horanyi, P.S, Coleman, J.A. 登録日 2023-10-19 公開日 2024-05-22 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structures of synaptic vesicle protein 2A and 2B bound to anticonvulsants. Nat.Struct.Mol.Biol., 2024

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