Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

4WXA
DownloadVisualize
BU of 4wxa by Molmil
Crystal structure of binary complex Gon7-Pcc1
分子名称: ACETATE ION, EKC/KEOPS complex subunit GON7, EKC/KEOPS complex subunit PCC1, ...
著者Zhang, W, van Tilbeurgh, H.
登録日2014-11-13
公開日2015-03-18
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Crystal structures of the Gon7/Pcc1 and Bud32/Cgi121 complexes provide a model for the complete yeast KEOPS complex.
Nucleic Acids Res., 43, 2015
3TG5
DownloadVisualize
BU of 3tg5 by Molmil
Structure of SMYD2 in complex with p53 and SAH
分子名称: Cellular tumor antigen p53, GLYCEROL, N-lysine methyltransferase SMYD2, ...
著者Zhao, K, Wang, L.
登録日2011-08-17
公開日2011-08-31
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of human SMYD2 reveals the basis of p53 tumor suppressor methylation
J.Biol.Chem., 2011
7SN8
DownloadVisualize
BU of 7sn8 by Molmil
Cryo-EM structure of Drosophila Integrator cleavage module (IntS4-IntS9-IntS11) in complex with IP6
分子名称: INOSITOL HEXAKISPHOSPHATE, Integrator complex subunit 11, Integrator complex subunit 4, ...
著者Lin, M, Tong, L.
登録日2021-10-27
公開日2022-10-12
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.74 Å)
主引用文献Inositol hexakisphosphate is required for Integrator function.
Nat Commun, 13, 2022
3NEW
DownloadVisualize
BU of 3new by Molmil
p38-alpha complexed with Compound 10
分子名称: 4-(trifluoromethyl)-3-[3-(trifluoromethyl)phenyl]-1,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one, Mitogen-activated protein kinase 14
著者Goedken, E.R, Comess, K.M, Sun, C, Argiriadi, M, Jia, Y, Quinn, C.M, Banach, D.L, Marcotte, D, Borhani, D.
登録日2010-06-09
公開日2010-12-01
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Discovery and Characterization of Non-ATP Site Inhibitors of the Mitogen Activated Protein (MAP) Kinases.
Acs Chem.Biol., 6, 2011
1N6J
DownloadVisualize
BU of 1n6j by Molmil
Structural basis of sequence-specific recruitment of histone deacetylases by Myocyte Enhancer Factor-2
分子名称: 5'-D(*AP*GP*CP*TP*AP*TP*TP*TP*AP*TP*AP*AP*GP*C)-3', 5'-D(*GP*CP*TP*TP*AP*TP*AP*AP*AP*TP*AP*GP*CP*T)-3', Calcineurin-binding protein Cabin 1, ...
著者Han, A, Pan, F, Stroud, J.C, Youn, H.D, Liu, J.O, Chen, L.
登録日2002-11-11
公開日2003-11-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Sequence-specific recruitment of transcriptional co-repressor Cabin1 by myocyte enhancer factor-2
Nature, 422, 2003
4F7P
DownloadVisualize
BU of 4f7p by Molmil
Crystal Structure of HLA-A*2402 Complexed with a Newly Identified Peptide from 2009H1N1 PB1 (496-505)
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-24 alpha chain, ...
著者Liu, J, Zhang, S, Tan, S, Yi, Y, Wu, B, Zhu, F, Wang, H, Qi, J, Gao, G.F.
登録日2012-05-16
公開日2012-10-10
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Cross-Allele Cytotoxic T Lymphocyte Responses against 2009 Pandemic H1N1 Influenza A Virus among HLA-A24 and HLA-A3 Supertype-Positive Individuals.
J.Virol., 86, 2012
4JR7
DownloadVisualize
BU of 4jr7 by Molmil
Crystal structure of scCK2 alpha in complex with GMPPNP
分子名称: Casein kinase II subunit alpha, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
著者Liu, H.
登録日2013-03-21
公開日2014-03-05
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献The multiple nucleotide-divalent cation binding modes of Saccharomyces cerevisiae CK2 alpha indicate a possible co-substrate hydrolysis product (ADP/GDP) release pathway.
Acta Crystallogr.,Sect.D, 70, 2014
4JQE
DownloadVisualize
BU of 4jqe by Molmil
Crystal structure of scCK2 alpha in complex with AMPPN
分子名称: Casein kinase II subunit alpha, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Liu, H.
登録日2013-03-20
公開日2014-03-05
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献The multiple nucleotide-divalent cation binding modes of Saccharomyces cerevisiae CK2 alpha indicate a possible co-substrate hydrolysis product (ADP/GDP) release pathway.
Acta Crystallogr.,Sect.D, 70, 2014
8OR3
DownloadVisualize
BU of 8or3 by Molmil
CAND1-CUL1-RBX1-SKP1-SKP2-DCNL1
分子名称: Cullin-1, Cullin-associated NEDD8-dissociated protein 1, DCN1-like protein 1, ...
著者Shaaban, M, Clapperton, J.A, Ding, S, Maeots, M.E, Enchev, R.I.
登録日2023-04-13
公開日2023-06-28
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural and mechanistic insights into the CAND1-mediated SCF substrate receptor exchange.
Mol.Cell, 83, 2023
1A7M
DownloadVisualize
BU of 1a7m by Molmil
LEUKAEMIA INHIBITORY FACTOR CHIMERA (MH35-LIF), NMR, 20 STRUCTURES
分子名称: LEUKEMIA INHIBITORY FACTOR
著者Hinds, M.G, Maurer, T, Zhang, J.-G, Nicola, N.A, Norton, R.S.
登録日1998-03-16
公開日1999-04-20
最終更新日2022-02-16
実験手法SOLUTION NMR
主引用文献Solution structure of leukemia inhibitory factor.
J.Biol.Chem., 273, 1998
2FSM
DownloadVisualize
BU of 2fsm by Molmil
mitogen activated protein kinase p38alpha (D176A+F327S) activating mutant form-B
分子名称: Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside
著者Diskin, R, Livnah, O.
登録日2006-01-23
公開日2006-12-05
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Structures of p38alpha Active Mutants Reveal Conformational Changes in L16 Loop that Induce Autophosphorylation and Activation
J.Mol.Biol., 365, 2007
2FST
DownloadVisualize
BU of 2fst by Molmil
mitogen activated protein kinase p38alpha (D176A+F327L) activating mutant
分子名称: Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside
著者Diskin, R, Livnah, O.
登録日2006-01-23
公開日2006-12-05
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structures of p38alpha Active Mutants Reveal Conformational Changes in L16 Loop that Induce Autophosphorylation and Activation
J.Mol.Biol., 365, 2007
1A02
DownloadVisualize
BU of 1a02 by Molmil
STRUCTURE OF THE DNA BINDING DOMAINS OF NFAT, FOS AND JUN BOUND TO DNA
分子名称: AP-1 FRAGMENT FOS, AP-1 FRAGMENT JUN, DNA (5'-D(*DAP*DAP*DCP*DTP*DAP*DTP*DGP*DAP*DAP*DAP*DCP*DAP*DAP*DAP*DTP*DTP*DTP*DTP*DCP*DC)-3'), ...
著者Chen, L, Glover, J.N.M, Hogan, P.G, Rao, A, Harrison, S.C.
登録日1997-12-08
公開日1998-05-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of the DNA-binding domains from NFAT, Fos and Jun bound specifically to DNA.
Nature, 392, 1998
6O3Y
DownloadVisualize
BU of 6o3y by Molmil
Crystal structure of yeast Nrd1 CID in complex with Sen1 NIM3
分子名称: CHLORIDE ION, Helicase SEN1, Protein NRD1
著者Zhang, Y, Tong, L.
登録日2019-02-27
公開日2019-06-05
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.799 Å)
主引用文献Identification of Three Sequence Motifs in the Transcription Termination Factor Sen1 that Mediate Direct Interactions with Nrd1.
Structure, 27, 2019
6AFB
DownloadVisualize
BU of 6afb by Molmil
DJ-1 C106S incubated with isatin
分子名称: CHLORIDE ION, DIMETHYL SULFOXIDE, ISATIN, ...
著者Caaveiro, J.M.M, Tashiro, S, Tsumoto, K.
登録日2018-08-08
公開日2018-08-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1.
ACS Chem. Biol., 13, 2018
6AFL
DownloadVisualize
BU of 6afl by Molmil
DJ-1 with compound 15
分子名称: 5-fluoranyl-1-(2-phenylethyl)indole-2,3-dione, CHLORIDE ION, Protein/nucleic acid deglycase DJ-1
著者Caaveiro, J.M.M, Tashiro, S, Tsumoto, K.
登録日2018-08-08
公開日2018-08-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1.
ACS Chem. Biol., 13, 2018
6AF5
DownloadVisualize
BU of 6af5 by Molmil
DJ-1 after backsoaking
分子名称: CHLORIDE ION, ISATIN, Protein/nucleic acid deglycase DJ-1
著者Caaveiro, J.M.M, Tashiro, S, Tsumoto, K.
登録日2018-08-08
公開日2018-08-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1.
ACS Chem. Biol., 13, 2018
6AFG
DownloadVisualize
BU of 6afg by Molmil
DJ-1 with compound 9
分子名称: 1-methylindole-2,3-dione, Protein/nucleic acid deglycase DJ-1
著者Caaveiro, J.M.M, Tashiro, S, Tsumoto, K.
登録日2018-08-08
公開日2018-08-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1.
ACS Chem. Biol., 13, 2018
6AFH
DownloadVisualize
BU of 6afh by Molmil
DJ-1 with compound 10
分子名称: 1-(2-phenylethyl)indole-2,3-dione, CHLORIDE ION, Protein/nucleic acid deglycase DJ-1
著者Caaveiro, J.M.M, Tashiro, S, Tsumoto, K.
登録日2018-08-08
公開日2018-08-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1.
ACS Chem. Biol., 13, 2018
5LCJ
DownloadVisualize
BU of 5lcj by Molmil
In-Gel Activity-Based Protein Profiling of a Clickable Covalent Erk 1/2 Inhibitor
分子名称: Mitogen-activated protein kinase 1, SULFATE ION, [(1~{R},4~{Z})-cyclooct-4-en-1-yl] ~{N}-[4-[4-[[5-chloranyl-4-[[2-(propanoylamino)phenyl]amino]pyrimidin-2-yl]amino]pyridin-2-yl]but-3-ynyl]carbamate
著者O'Reilly, M, Wright, D.
登録日2016-06-22
公開日2016-07-20
最終更新日2016-08-31
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献In-gel activity-based protein profiling of a clickable covalent ERK1/2 inhibitor.
Mol Biosyst, 12, 2016
2FSO
DownloadVisualize
BU of 2fso by Molmil
mitogen activated protein kinase p38alpha (D176A) activating mutant
分子名称: Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside
著者Diskin, R, Livnah, O.
登録日2006-01-23
公開日2006-12-05
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Structures of p38alpha Active Mutants Reveal Conformational Changes in L16 Loop that Induce Autophosphorylation and Activation
J.Mol.Biol., 365, 2007
6AFA
DownloadVisualize
BU of 6afa by Molmil
DJ-1 with isatin (low concentration)
分子名称: CHLORIDE ION, ISATIN, Protein/nucleic acid deglycase DJ-1
著者Caaveiro, J.M.M, Tashiro, S, Tsumoto, K.
登録日2018-08-08
公開日2018-08-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1.
ACS Chem. Biol., 13, 2018
6O3X
DownloadVisualize
BU of 6o3x by Molmil
Crystal structure of yeast Nrd1 CID in complex with Sen1 NIM2
分子名称: CHLORIDE ION, Helicase SEN1, Protein NRD1
著者Zhang, Y, Tong, L.
登録日2019-02-27
公開日2019-06-05
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.994 Å)
主引用文献Identification of Three Sequence Motifs in the Transcription Termination Factor Sen1 that Mediate Direct Interactions with Nrd1.
Structure, 27, 2019
2FSL
DownloadVisualize
BU of 2fsl by Molmil
mitogen activated protein kinase p38alpha (D176A+F327S) activating mutant form-A
分子名称: Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside
著者Diskin, R, Livnah, O.
登録日2006-01-23
公開日2006-12-05
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structures of p38alpha Active Mutants Reveal Conformational Changes in L16 Loop that Induce Autophosphorylation and Activation
J.Mol.Biol., 365, 2007
8T2T
DownloadVisualize
BU of 8t2t by Molmil
Structure of a group II intron ribonucleoprotein in the post-ligation (post-2F) state
分子名称: AMMONIUM ION, Group II intron reverse transcriptase/maturase, MAGNESIUM ION, ...
著者Xu, L, Liu, T, Chung, K, Pyle, A.M.
登録日2023-06-06
公開日2023-11-22
最終更新日2024-01-03
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural insights into intron catalysis and dynamics during splicing.
Nature, 624, 2023

223532

件を2024-08-07に公開中

PDB statisticsPDBj update infoContact PDBjnumon