8BJA
 
 | |
7KXT
 | | Crystal structure of human EED | | 分子名称: | 1-[(4-fluorophenyl)methyl]-N-{1-[2-(4-methoxyphenyl)ethyl]piperidin-4-yl}-1H-benzimidazol-2-amine, Polycomb protein EED, UNKNOWN ATOM OR ION | | 著者 | Zhu, L, Dong, A, Du, D, Liu, Y, Luo, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2020-12-04 | | 公開日 | 2021-02-24 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2-EED Interaction.
J.Med.Chem., 64, 2021
|
|
4KMR
 | | Structure of a putative transcriptional regulator of LacI family from Sanguibacter keddieii DSM 10542. | | 分子名称: | MAGNESIUM ION, SODIUM ION, Transcriptional regulator, ... | | 著者 | Filippova, E.V, Minasov, G, Shuvalova, L, Kiryukhina, O, Endres, M, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2013-05-08 | | 公開日 | 2013-06-05 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Structure of a putative transcriptional regulator of LacI family from Sanguibacter keddieii DSM 10542.
To be Published
|
|
1IPC
 | | CRYSTAL STRUCTURE OF EUKARYOTIC INITIATION FACTOR 4E COMPLEXED WITH 7-METHYL GTP | | 分子名称: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E | | 著者 | Tomoo, K, Shen, X, Okabe, K, Nozoe, Y, Fukuhara, S, Morino, S, Ishida, T, Taniguchi, T, Hasegawa, H, Terashima, A, Sasaki, M, Katsuya, Y, Kitamura, K, Miyoshi, H, Ishikawa, M, Miura, K. | | 登録日 | 2001-05-08 | | 公開日 | 2002-05-08 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structures of 7-methylguanosine 5'-triphosphate (m(7)GTP)- and
P(1)-7-methylguanosine-P(3)-adenosine-5',5'-triphosphate (m(7)GpppA)-bound human full-length eukaryotic
initiation factor 4E: biological importance of the C-terminal flexible region
BIOCHEM.J., 362, 2002
|
|
2XDB
 | | A processed non-coding RNA regulates a bacterial antiviral system | | 分子名称: | COBALT (II) ION, SULFATE ION, TOXI, ... | | 著者 | Blower, T.R, Pei, X.Y, Short, F.L, Fineran, P.C, Humphreys, D.P, Luisi, B.F, Salmond, G.P.C. | | 登録日 | 2010-04-30 | | 公開日 | 2011-01-12 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | A Processed Noncoding RNA Regulates an Altruistic Bacterial Antiviral System.
Nat.Struct.Mol.Biol., 18, 2011
|
|
2XDD
 | | A processed non-coding RNA regulates a bacterial antiviral system | | 分子名称: | TOXI, TOXN, ZINC ION | | 著者 | Blower, T.R, Pei, X.Y, Short, F.L, Fineran, P.C, Humphreys, D.P, Luisi, B.F, Salmond, G.P.C. | | 登録日 | 2010-04-30 | | 公開日 | 2011-01-12 | | 最終更新日 | 2015-09-16 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | The Phage Abortive Infection System, Toxin, Functions as a Protein-RNA Toxin-Antitoxin Pair.
Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
2XDV
 | | Crystal Structure of the Catalytic Domain of FLJ14393 | | 分子名称: | 1,2-ETHANEDIOL, CADMIUM ION, MANGANESE (II) ION, ... | | 著者 | Krojer, T, Muniz, J.R.C, Ng, S.S, Pilka, E, Guo, K, Pike, A.C.W, Filippakopoulos, P, Knapp, S, Kavanagh, K.L, Gileadi, O, Bunkoczi, G, Yue, W.W, Niesen, F, Sobott, F, Fedorov, O, Savitsky, P, Kochan, G, Daniel, M, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Oppermann, U. | | 登録日 | 2010-05-07 | | 公開日 | 2010-05-26 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | | 主引用文献 | Ribosomal oxygenases are structurally conserved from prokaryotes to humans.
Nature, 510, 2014
|
|
1ITF
 | | INTERFERON ALPHA-2A, NMR, 24 STRUCTURES | | 分子名称: | INTERFERON ALPHA-2A | | 著者 | Klaus, W, Gsell, B, Labhardt, A.M, Wipf, B, Senn, H. | | 登録日 | 1997-08-22 | | 公開日 | 1997-12-03 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The three-dimensional high resolution structure of human interferon alpha-2a determined by heteronuclear NMR spectroscopy in solution.
J.Mol.Biol., 274, 1997
|
|
2XUM
 | | FACTOR INHIBITING HIF (FIH) Q239H MUTANT IN COMPLEX WITH ZN(II), NOG AND ASP-SUBSTRATE PEPTIDE (20-MER) | | 分子名称: | ASP-SUBSTRATE PEPTIDE 2, HYPOXIA-INDUCIBLE FACTOR 1-ALPHA INHIBITOR, N-OXALYLGLYCINE, ... | | 著者 | Chowdhury, R, McDonough, M.A, Schofield, C.J. | | 登録日 | 2010-10-19 | | 公開日 | 2010-12-22 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Asparagine and aspartate hydroxylation of the cytoskeletal ankyrin family is catalyzed by factor-inhibiting hypoxia-inducible factor.
J. Biol. Chem., 286, 2011
|
|
4KG0
 | | Crystal structure of the drosophila melanogaster neuralized-nhr1 domain | | 分子名称: | MAGNESIUM ION, Protein neuralized | | 著者 | Gupta, D, Ehebauer, M.T, Chirgadze, D.Y, Bolanos-Garcia, V.M, Blundell, T.L. | | 登録日 | 2013-04-28 | | 公開日 | 2014-01-15 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure, biochemical and biophysical characterisation of NHR1 domain of E3 Ubiquitin ligase neutralized
Advances in Enzyme Research, 1, 2013
|
|
8W8G
 | | Crystal structure of human TRF1 with PinX1 | | 分子名称: | HEXANE-1,6-DIOL, PIN2/TERF1-interacting telomerase inhibitor 1, Telomeric repeat-binding factor 1 | | 著者 | Lei, M, Wu, J. | | 登録日 | 2023-09-02 | | 公開日 | 2024-09-04 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | PinX1 suppress tumorigenesis through inhibiting telomerase activity
To Be Published
|
|
1WMH
 | | Crystal structure of a PB1 domain complex of Protein kinase c iota and Par6 alpha | | 分子名称: | Partitioning defective-6 homolog alpha, Protein kinase C, iota type | | 著者 | Hirano, Y, Yoshinaga, S, Suzuki, N.N, Horiuchi, M, Kohjima, M, Takeya, R, Sumimoto, H, Inagaki, F. | | 登録日 | 2004-07-09 | | 公開日 | 2004-12-07 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structure of a Cell Polarity Regulator, a Complex between Atypical PKC and Par6 PB1 Domains
J.Biol.Chem., 280, 2005
|
|
1HI1
 | | RNA dependent RNA polymerase from dsRNA bacteriophage phi6 plus bound NTP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, P2 PROTEIN | | 著者 | Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. | | 登録日 | 2001-01-01 | | 公開日 | 2001-03-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | A Mechanism for Initiating RNA-Dependent RNA Polymerization
Nature, 410, 2001
|
|
1WPU
 | |
7JVW
 | | Crystal structure of human histone deacetylase 8 (HDAC8) G320R mutation complexed with M344 | | 分子名称: | 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, Histone deacetylase 8, POTASSIUM ION, ... | | 著者 | Osko, J.D, Christianson, D.W, Decroos, C, Porter, N.J, Lee, M. | | 登録日 | 2020-08-24 | | 公開日 | 2020-12-16 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.40301776 Å) | | 主引用文献 | Structural analysis of histone deacetylase 8 mutants associated with Cornelia de Lange Syndrome spectrum disorders.
J.Struct.Biol., 213, 2020
|
|
1WRO
 | | Metal Ion dependency of the antiterminator protein, HutP, for binding to the terminator region of hut mRNA- A structural basis | | 分子名称: | BARIUM ION, HISTIDINE, Hut operon positive regulatory protein | | 著者 | Kumarevel, T, Mizuno, H, Kumar, P.K.R. | | 登録日 | 2004-10-25 | | 公開日 | 2005-08-30 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Characterization of the metal ion binding site in the anti-terminator protein, HutP, of Bacillus subtilis
Nucleic Acids Res., 33, 2005
|
|
1WZ3
 | | The crystal structure of plant ATG12 | | 分子名称: | autophagy 12b | | 著者 | Suzuki, N.N, Yoshimoto, K, Fujioka, Y, Ohsumi, Y, Inagaki, F. | | 登録日 | 2005-02-22 | | 公開日 | 2005-06-21 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The crystal structure of plant ATG12 and its biological implication in autophagy.
Autophagy, 1, 2005
|
|
1HKU
 | | CtBP/BARS: a dual-function protein involved in transcription corepression and Golgi membrane fission | | 分子名称: | C-TERMINAL BINDING PROTEIN 3, FORMIC ACID, GLYCEROL, ... | | 著者 | Nardini, M, Spano, S, Cericola, C, Pesce, A, Massaro, A, Millo, E, Luini, A, Corda, D, Bolognesi, M. | | 登録日 | 2003-03-11 | | 公開日 | 2003-06-19 | | 最終更新日 | 2016-12-21 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Ctbp/Bars: A Dual-Function Protein Involved in Transcription Co-Repression and Golgi Membrane Fission
Embo J., 22, 2003
|
|
1HX5
 | |
8VJ4
 | | X-ray Counterpart to the Neutron Structure of Peroxide-Soaked Trp161Phe MnSOD | | 分子名称: | HYDROGEN PEROXIDE, MANGANESE (II) ION, Superoxide dismutase [Mn], ... | | 著者 | Azadmanesh, J, Slobodnik, K, Struble, L.R, Lutz, W.E, Weiss, K.L, Myles, D.A.A, Kroll, T, Borgstahl, G.E.O. | | 登録日 | 2024-01-05 | | 公開日 | 2024-07-31 | | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | | 主引用文献 | Revealing the atomic and electronic mechanism of human manganese superoxide dismutase product inhibition.
Biorxiv, 2024
|
|
8VHW
 | | Neutron Structure of Peroxide-Soaked Trp161Phe MnSOD | | 分子名称: | HYDROGEN PEROXIDE, MANGANESE (II) ION, Superoxide dismutase [Mn], ... | | 著者 | Azadmanesh, J, Slobodnik, K, Struble, L.R, Lutz, W.E, Coates, L, Weiss, K.L, Myles, D.A.A, Kroll, T, Borgstahl, G.E.O. | | 登録日 | 2024-01-02 | | 公開日 | 2024-07-31 | | 実験手法 | NEUTRON DIFFRACTION (2.3 Å) | | 主引用文献 | Revealing the atomic and electronic mechanism of human manganese superoxide dismutase product inhibition.
Biorxiv, 2024
|
|
8VHY
 | | Neutron Structure of Reduced Trp161Phe MnSOD | | 分子名称: | MANGANESE (II) ION, Superoxide dismutase [Mn], mitochondrial | | 著者 | Azadmanesh, J, Slobodnik, K, Struble, L.R, Lutz, W.E, Coates, L, Weiss, K.L, Myles, D.A.A, Kroll, T, Borgstahl, G.E.O. | | 登録日 | 2024-01-02 | | 公開日 | 2024-07-31 | | 実験手法 | NEUTRON DIFFRACTION (2.3 Å) | | 主引用文献 | Revealing the atomic and electronic mechanism of human manganese superoxide dismutase product inhibition.
Biorxiv, 2024
|
|
8VJ5
 | | Peroxide-Soaked MnSOD | | 分子名称: | HYDROGEN PEROXIDE, MANGANESE (II) ION, PHOSPHATE ION, ... | | 著者 | Azadmanesh, J, Slobodnik, K, Struble, L.R, Lutz, W.E, Weiss, K.L, Myles, D.A.A, Kroll, T, Borgstahl, G.E.O. | | 登録日 | 2024-01-05 | | 公開日 | 2024-07-31 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Revealing the atomic and electronic mechanism of human manganese superoxide dismutase product inhibition.
Biorxiv, 2024
|
|
8VJ0
 | | Neutron Structure of Oxidized Trp161Phe MnSOD | | 分子名称: | MANGANESE (II) ION, Superoxide dismutase [Mn], mitochondrial | | 著者 | Azadmanesh, J, Slobodnik, K, Struble, L.R, Lutz, W.E, Weiss, K.L, Myles, D.A.A, Kroll, T, Borgstahl, G.E.O. | | 登録日 | 2024-01-05 | | 公開日 | 2024-07-31 | | 実験手法 | NEUTRON DIFFRACTION (2.3 Å) | | 主引用文献 | Revealing the atomic and electronic mechanism of human manganese superoxide dismutase product inhibition.
Biorxiv, 2024
|
|
8VJ8
 | | X-ray Counterpart to Neutron Structure of Reduced Trp161Phe MnSOD | | 分子名称: | MANGANESE (II) ION, PHOSPHATE ION, POTASSIUM ION, ... | | 著者 | Azadmanesh, J, Slobodnik, K, Struble, L.R, Lutz, W.E, Weiss, K.L, Myles, D.A.A, Kroll, T, Borgstahl, G.E.O. | | 登録日 | 2024-01-05 | | 公開日 | 2024-07-31 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Revealing the atomic and electronic mechanism of human manganese superoxide dismutase product inhibition.
Biorxiv, 2024
|
|
