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8SLZ
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Crystal structure of phosphorylated (T357/S358) human MLKL pseudokinase domain
分子名称: Mixed lineage kinase domain-like protein
著者Meng, Y, Davies, K.A, Czabotar, P.E, Murphy, J.M.
登録日2023-04-25
公開日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Phosphorylation-dependent pseudokinase domain dimerization drives full-length MLKL oligomerization.
Nat Commun, 14, 2023
6FIJ
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Structure of the loading/condensing region (SAT-KS-MAT) of the cercosporin fungal non-reducing polyketide synthase (NR-PKS) CTB1
分子名称: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GLYCEROL, ...
著者Herbst, D.A, Jakob, R.P, Townsend, C.A, Maier, T.
登録日2018-01-18
公開日2018-03-21
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.77 Å)
主引用文献The structural organization of substrate loading in iterative polyketide synthases.
Nat. Chem. Biol., 14, 2018
6XJS
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Crystal Structure of KPT-330 bound to CRM1 (E582K, 537-DLTVK-541 to GLCEQ)
分子名称: Exportin-1, GLYCEROL, GTP-binding nuclear protein Ran, ...
著者Baumhardt, J.M, Chook, Y.M.
登録日2020-06-24
公開日2021-01-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.942 Å)
主引用文献Recurrent XPO1 mutations alter pathogenesis of chronic lymphocytic leukemia.
J Hematol Oncol, 14, 2021
7UUI
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Nucleoplasmic pre-60S intermediate of the Nog2 containing post-rotation state from a SPB1 D52A strain
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Nucleolar GTP-binding protein 2, ...
著者Sekulski, K, Cruz, V.E, Weirich, C.S, Erzberger, J.P.
登録日2022-04-28
公開日2023-03-15
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly.
Nat Commun, 14, 2023
6H7E
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GEF regulatory domain
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SULFATE ION, cDNA FLJ56134, ...
著者Ferrandez, Y, Cherfils, J, Peurois, F.
登録日2018-07-31
公開日2020-02-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Membranes prime the RapGEF EPAC1 to transduce cAMP signaling.
Nat Commun, 14, 2023
6EYB
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Estimation of relative drug-target residence times by random acceleration molecular dynamics simulation
分子名称: 3-(phenylmethyl)-5-(2-phenylpyrazol-3-yl)-2~{H}-indazol-6-ol, Heat shock protein HSP 90-alpha, SULFATE ION
著者Musil, D, Lehmann, M, Buchstaller, H.-P.
登録日2017-11-11
公開日2018-05-30
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Estimation of Drug-Target Residence Times by tau-Random Acceleration Molecular Dynamics Simulations.
J Chem Theory Comput, 14, 2018
8QME
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BU of 8qme by Molmil
Structural characterization of beta-xyloxidase XynB2 from Geobacillus stearothermophilus CECT43
分子名称: ACETATE ION, Beta-xylosidase, GLYCEROL, ...
著者Gavira, J.A, Martinez-Rodriguez, S.
登録日2023-09-22
公開日2024-03-27
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural Characterization of beta-Xylosidase XynB2 from Geobacillus stearothermophilus CECT43: A Member of the Glycoside Hydrolase Family GH52
Crystals, 14, 2024
6F1N
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Estimation of relative drug-target residence times by random acceleration molecular dynamics simulation
分子名称: 4-[5-[2-aminocarbonyl-3,6-bis(azanyl)-5-cyano-thieno[2,3-b]pyridin-4-yl]-2-methoxy-phenoxy]butanoic acid, Heat shock protein HSP 90-alpha, SULFATE ION
著者Musil, D, Lehmann, M, Eggenweiler, H.-M.
登録日2017-11-22
公開日2018-05-30
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Estimation of Drug-Target Residence Times by tau-Random Acceleration Molecular Dynamics Simulations.
J Chem Theory Comput, 14, 2018
7UIB
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Crystal structure of BoNT/E receptor binding domain in complex with SV2, VHH, and sialic acid
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-beta-neuraminic acid, ...
著者Liu, Z, Jin, R, Chen, P.
登録日2022-03-29
公開日2023-04-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.77 Å)
主引用文献Structural basis for botulinum neurotoxin E recognition of synaptic vesicle protein 2.
Nat Commun, 14, 2023
6XUU
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Crystallographic structure of oligosaccharide dehydrogenase from Pycnoporus cinnabarinus, glucose-bound form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Cerutti, G, Savino, C, Montemiglio, L.C, Vallone, B, Sciara, G.
登録日2020-01-21
公開日2021-02-03
最終更新日2021-08-11
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Crystal structure and functional characterization of an oligosaccharide dehydrogenase from Pycnoporus cinnabarinus provides insights into fungal breakdown of lignocellulose.
Biotechnol Biofuels, 14, 2021
7UOP
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Prefusion-stabilized Nipah virus fusion protein complexed with Fab 4H3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 4H3 heavy chain, Fab 4H3 light chain, ...
著者Byrne, P.O, McLellan, J.S.
登録日2022-04-13
公開日2023-03-29
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis for antibody recognition of vulnerable epitopes on Nipah virus F protein.
Nat Commun, 14, 2023
7UP9
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Prefusion-stabilized Nipah virus fusion protein complexed with Fab 2D3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 2D3 heavy chain, ...
著者Byrne, P.O, McLellan, J.S.
登録日2022-04-14
公開日2023-03-29
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis for antibody recognition of vulnerable epitopes on Nipah virus F protein.
Nat Commun, 14, 2023
7UPD
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Prefusion-stabilized Nipah virus fusion protein complexed with Fab 2B12
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 2B12 heavy chain, Fab 2B12 light chain, ...
著者Byrne, P.O, McLellan, J.S.
登録日2022-04-14
公開日2023-03-29
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Structural basis for antibody recognition of vulnerable epitopes on Nipah virus F protein.
Nat Commun, 14, 2023
7UPA
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BU of 7upa by Molmil
Prefusion-stabilized Nipah virus fusion protein complexed with Fab 1H8
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 1H8 heavy chain, Fab 1H8 light chain, ...
著者Byrne, P.O, McLellan, J.S.
登録日2022-04-14
公開日2023-03-29
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Structural basis for antibody recognition of vulnerable epitopes on Nipah virus F protein.
Nat Commun, 14, 2023
7UIA
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BU of 7uia by Molmil
Crystal structure of BoNT/E receptor binding domain in complex with SV2 and VHH
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ...
著者Liu, Z, Jin, R, Chen, P.
登録日2022-03-28
公開日2023-04-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Structural basis for botulinum neurotoxin E recognition of synaptic vesicle protein 2.
Nat Commun, 14, 2023
7UIE
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BU of 7uie by Molmil
Crystal structure of HcE-JLE-G6
分子名称: Botulinum neurotoxin E heavy chain, JLE-G6
著者Jin, R, Lam, K.
登録日2022-03-29
公開日2023-04-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.23 Å)
主引用文献Structural basis for botulinum neurotoxin E recognition of synaptic vesicle protein 2.
Nat Commun, 14, 2023
7UJ2
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OspC Type B
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Outer surface protein C
著者Rudolph, M.J, Mantis, N.
登録日2022-03-30
公開日2023-04-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.503 Å)
主引用文献Structural Elucidation of a Protective B Cell Epitope on Outer Surface Protein C (OspC) of the Lyme Disease Spirochete, Borreliella burgdorferi.
Mbio, 14, 2023
7UPB
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BU of 7upb by Molmil
Prefusion-stabilized Nipah virus fusion protein complexed with Fab 1H1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 1H1 heavy chain, Fab 1H1 light chain, ...
著者Byrne, P.O, McLellan, J.S.
登録日2022-04-14
公開日2023-03-29
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis for antibody recognition of vulnerable epitopes on Nipah virus F protein.
Nat Commun, 14, 2023
7UPK
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BU of 7upk by Molmil
Prefusion-stabilized Nipah virus fusion protein complexed with Fab 1A9
分子名称: Fab 1A9 heavy chain, Fab 1A9 light chain, Fusion glycoprotein F0
著者Byrne, P.O, McLellan, J.S.
登録日2022-04-15
公開日2023-03-29
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis for antibody recognition of vulnerable epitopes on Nipah virus F protein.
Nat Commun, 14, 2023
7UJ6
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Outer Surface Protein C Type K
分子名称: Outer surface protein C
著者Rudolph, M.J, Mantis, N.
登録日2022-03-30
公開日2023-04-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.951 Å)
主引用文献Structural Elucidation of a Protective B Cell Epitope on Outer Surface Protein C (OspC) of the Lyme Disease Spirochete, Borreliella burgdorferi.
Mbio, 14, 2023
7UIJ
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BU of 7uij by Molmil
Structural studies of B5-OspC complex
分子名称: 1,2-ETHANEDIOL, Monoclonal B5 Fab Heavy Chain, Monoclonal B5 Fab Light Chain, ...
著者Rudolph, M.J, Mantis, N.
登録日2022-03-29
公開日2023-04-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.701 Å)
主引用文献Structural Elucidation of a Protective B Cell Epitope on Outer Surface Protein C (OspC) of the Lyme Disease Spirochete, Borreliella burgdorferi.
Mbio, 14, 2023
7UQA
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BU of 7uqa by Molmil
Crystal structure of the small Ultra-Red Fluorescent Protein (smURFP)
分子名称: CHLORIDE ION, SODIUM ION, small Ultra-Red Fluorescent Protein (smURFP)
著者Maiti, A, Buffalo, C.Z, Saurabh, S, Montecinos-Franjola, F, Hachey, J.S, Conlon, W.J, Tran, G.N, Drobizhev, M, Moerner, W.E, Ghosh, P, Matsuo, H, Tsien, R.Y, Lin, J.Y, Rodriguez, E.A.
登録日2022-04-19
公開日2023-07-19
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.802 Å)
主引用文献Structural and photophysical characterization of the small ultra-red fluorescent protein.
Nat Commun, 14, 2023
8QC0
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Nucleoside 2'deoxyribosyltransferase from Chroococcidiopsis thermalis PCC 7203 WT ribosylated
分子名称: Nucleoside 2-deoxyribosyltransferase, ZINC ION, alpha-D-ribofuranose
著者Tang, P, Harding, C.J, Czekster, C.M.
登録日2023-08-25
公開日2024-02-21
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Snapshots of the Reaction Coordinate of a Thermophilic 2'-Deoxyribonucleoside/ribonucleoside Transferase.
Acs Catalysis, 14, 2024
8QB1
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C-terminal domain of mirolase from Tannerella forsythia
分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Mirolase, ...
著者Gomis-Ruth, F.X, Rodriguez-Banqueri, A, Mizgalska, D, Veillard, F, Goulas, T, Eckhard, U, Potempa, J.
登録日2023-08-23
公開日2024-02-28
最終更新日2024-06-26
実験手法X-RAY DIFFRACTION (1.601 Å)
主引用文献Structural and functional insights into the C-terminal signal domain of the Bacteroidetes type-IX secretion system.
Open Biology, 14, 2024
6H0U
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Glycogen synthase kinase-3 beta (GSK3) complex with a covalent [1,2,4]triazolo[1,5-a][1,3,5]triazine inhibitor
分子名称: (2~{R})-3-[7-azanyl-5-(cyclohexylamino)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-2-yl]-2-cyano-propanamide, CHLORIDE ION, GLYCEROL, ...
著者Marcovich, I, Demitri, N, De Zorzi, R, Storici, P.
登録日2018-07-10
公開日2019-05-15
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A Triazolotriazine-Based Dual GSK-3 beta /CK-1 delta Ligand as a Potential Neuroprotective Agent Presenting Two Different Mechanisms of Enzymatic Inhibition.
Chemmedchem, 14, 2019

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件を2024-09-11に公開中

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