PDB: 5434 件ウェブページステータス検索Chemie searchBIRD

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2B5M	Crystal Structure of DDB1 分子名称: damage-specific DNA binding protein 1 著者 Li, T, Chen, X, Garbutt, K.C, Zhou, P, Zheng, N. 登録日 2005-09-28 公開日 2006-02-28 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.92 Å) 主引用文献 Structure of DDB1 in complex with a paramyxovirus V protein: viral hijack of a propeller cluster in ubiquitin ligase. Cell(Cambridge,Mass.), 124, 2006
2OWB	Structure of the Catalytic Domain of Human Polo-like Kinase 1 分子名称: 4-(4-METHYLPIPERAZIN-1-YL)-N-[5-(2-THIENYLACETYL)-1,5-DIHYDROPYRROLO[3,4-C]PYRAZOL-3-YL]BENZAMIDE, ACETATE ION, Serine/threonine-protein kinase PLK1, ... 著者 Ding, Y.-H, Kothe, M, Kohls, D, Low, S. 登録日 2007-02-15 公開日 2007-04-24 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of the catalytic domain of human polo-like kinase 1. Biochemistry, 46, 2007
4JOL	Complex structure of AML1-ETO NHR2 domain with HEB fragment 分子名称: Protein CBFA2T1, Transcription factor 12 著者 Wang, Z, Patel, D.J. 登録日 2013-03-18 公開日 2013-06-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.906 Å) 主引用文献 A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis. Nature, 500, 2013
2P2R	Crystal structure of the third KH domain of human Poly(C)-Binding Protein-2 in complex with C-rich strand of human telomeric DNA 分子名称: 6-AMINOPYRIMIDIN-2(1H)-ONE, C-rich strand of human telomeric DNA, Poly(rC)-binding protein 2 著者 James, T.L, Stroud, R.M, Du, Z, Fenn, S, Tjhen, R, Lee, J.K. 登録日 2007-03-07 公開日 2007-06-12 最終更新日 2019-07-24 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of the third KH domain of human poly(C)-binding protein-2 in complex with a C-rich strand of human telomeric DNA at 1.6 A resolution. Nucleic Acids Res., 35, 2007
2EQ4	Solution structure of the 11th C2H2 type zinc finger domain of Zinc finger protein 224 分子名称: ZINC ION, Zinc finger protein 224 著者 Masuda, K, Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-03-30 公開日 2007-10-02 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the 11th C2H2 type zinc finger domain of Zinc finger protein 224 To be Published
2PX6	Crystal structure of the thioesterase domain of human fatty acid synthase inhibited by Orlistat 分子名称: (2S,3S,5S)-5-[(N-FORMYL-L-LEUCYL)OXY]-2-HEXYL-3-HYDROXYHEXADECANOIC ACID, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Thioesterase domain 著者 Pemble IV, C.W, Johnson, L.C, Kridel, S.J, Lowther, W.T. 登録日 2007-05-14 公開日 2007-07-10 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of the thioesterase domain of human fatty acid synthase inhibited by Orlistat. Nat.Struct.Mol.Biol., 14, 2007
2EQM	Solution structure of the TUDOR domain of PHD finger protein 20-like 1 [Homo sapiens] 分子名称: PHD finger protein 20-like 1 著者 Dang, W, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Tarada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-03-30 公開日 2007-10-02 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the TUDOR domain of PHD finger protein 20-like 1 [Homo sapiens] To be Published
2Q9Q	The crystal structure of full length human GINS complex 分子名称: DNA replication complex GINS protein PSF1, DNA replication complex GINS protein PSF2, GINS complex subunit 3, ... 著者 Chang, Y.P, Wang, G, Chen, X.S. 登録日 2007-06-13 公開日 2007-08-07 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 Crystal structure of the GINS complex and functional insights into its role in DNA replication. Proc.Natl.Acad.Sci.Usa, 104, 2007
2PA2	Crystal structure of human Ribosomal protein L10 core domain 分子名称: 60S ribosomal protein L10, POTASSIUM ION 著者 Nishimura, M, Kaminishi, T, Takemoto, C, Kawazoe, M, Yoshida, T, Tanaka, A, Sugano, S, Shirouzu, M, Ohkubo, T, Yokoyama, S, Kobayashi, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-03-27 公開日 2008-03-11 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal Structure of Human Ribosomal Protein L10 Core Domain Reveals Eukaryote-Specific Motifs in Addition to the Conserved Fold J.Mol.Biol., 377, 2008
2P6N	Human DEAD-box RNA helicase DDX41, helicase domain 分子名称: ATP-dependent RNA helicase DDX41 著者 Karlberg, T, Ogg, D, Arrowsmith, C.H, Berglund, H, Busam, R.D, Collins, R, Dahlgren, L.G, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hallberg, B.M, Hammarstrom, M, Johansson, I, Kotenyova, T, Lehtio, L, Moche, M, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC) 登録日 2007-03-19 公開日 2007-04-03 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Comparative Structural Analysis of Human DEAD-Box RNA Helicases. Plos One, 5, 2010
2P9I	Crystal Structure of bovine Arp2/3 Complex co-crystallized with ADP and crosslinked with gluteraldehyde 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin-like protein 2, Actin-like protein 3, ... 著者 Nolen, B.J, Pollard, T.D. 登録日 2007-03-26 公開日 2007-05-29 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.46 Å) 主引用文献 Insights into the Influence of Nucleotides on Actin Family Proteins from Seven Structures of Arp2/3 Complex. Mol.Cell, 26, 2007
4KO8	Structure of p97 N-D1 R155H mutant in complex with ATPgS 分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase 著者 Xia, D, Tang, W.K. 登録日 2013-05-11 公開日 2013-11-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Altered Intersubunit Communication Is the Molecular Basis for Functional Defects of Pathogenic p97 Mutants. J.Biol.Chem., 288, 2013
2P9K	Crystal structure of bovine Arp2/3 complex co-crystallized with ATP and crosslinked with glutaraldehyde 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin-like protein 2, Actin-like protein 3, ... 著者 Nolen, B.J, Pollard, T.D. 登録日 2007-03-26 公開日 2007-05-29 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 Insights into the Influence of Nucleotides on Actin Family Proteins from Seven Structures of Arp2/3 Complex. Mol.Cell, 26, 2007
2PJL	Crystal Structure of Human Estrogen-Related Receptor alpha in Complex with a Synthetic Inverse Agonist reveals its Novel Molecular Mechanism 分子名称: 1-CYCLOHEXYL-N-{[1-(4-METHYLPHENYL)-1H-INDOL-3-YL]METHYL}METHANAMINE, Steroid hormone receptor ERR1 著者 Kallen, J. 登録日 2007-04-16 公開日 2007-06-12 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of human estrogen-related receptor alpha in complex with a synthetic inverse agonist reveals its novel molecular mechanism. J.Biol.Chem., 282, 2007
2CPJ	Solution structure of the N-terminal RNA recognition motif of NonO 分子名称: Non-POU domain-containing octamer-binding protein 著者 Nagata, T, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-05-19 公開日 2005-11-19 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the N-terminal RNA recognition motif of NonO To be Published
4GV7	Human ARTD1 (PARP1) - Catalytic domain in complex with inhibitor ME0328 分子名称: 2-methylquinazolin-4(3H)-one, Poly [ADP-ribose] polymerase 1 著者 Karlberg, T, Thorsell, A.G, Lindgren, A.E.G, Ekblad, T, Spjut, S, Andersson, C.D, Weigelt, J, Linusson, A, Elofsson, M, Schuler, H. 登録日 2012-08-30 公開日 2013-06-19 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.89 Å) 主引用文献 PARP Inhibitor with Selectivity Toward ADP-Ribosyltransferase ARTD3/PARP3 Acs Chem.Biol., 8, 2013
2F1O	Crystal Structure of NQO1 with Dicoumarol 分子名称: BISHYDROXY[2H-1-BENZOPYRAN-2-ONE,1,2-BENZOPYRONE], FLAVIN-ADENINE DINUCLEOTIDE, NAD(P)H dehydrogenase [quinone] 1 著者 Shaul, Y, Asher, G, Dym, O, Tsvetkov, P, Adler, J, Israel Structural Proteomics Center (ISPC) 登録日 2005-11-15 公開日 2006-05-16 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 The crystal structure of NAD(P)H quinone oxidoreductase 1 in complex with its potent inhibitor dicoumarol. Biochemistry, 45, 2006
4HAT	Crystal structure of CRM1 inhibitor Leptomycin B in complex with CRM1-Ran-RanBP1 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-09-27 公開日 2013-01-09 最終更新日 2017-07-26 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
2FBX	WRN exonuclease, Mg complex 分子名称: MAGNESIUM ION, Werner syndrome helicase 著者 Perry, J.J. 登録日 2005-12-10 公開日 2006-04-25 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing. Nat.Struct.Mol.Biol., 13, 2006
4KMH	Crystal structure of Suppressor of Fused d20 分子名称: Suppressor of fused homolog 著者 Zhang, Y, Qi, X, Zhang, Z, Wu, G. 登録日 2013-05-08 公開日 2013-11-20 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.04 Å) 主引用文献 Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci. Nat Commun, 4, 2013
4K1N	Crystal structure of full-length mouse alphaE-catenin 分子名称: Catenin alpha-1 著者 Ishiyama, N, Ikura, M. 登録日 2013-04-05 公開日 2013-05-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (6.5 Å) 主引用文献 An autoinhibited structure of alpha-catenin and its implications for vinculin recruitment to adherens junctions. J.Biol.Chem., 288, 2013
4KOD	Structure of p97 N-D1 R155H mutant in complex with ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase 著者 Xia, D, Tang, W.K. 登録日 2013-05-11 公開日 2013-11-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.96 Å) 主引用文献 Altered Intersubunit Communication Is the Molecular Basis for Functional Defects of Pathogenic p97 Mutants. J.Biol.Chem., 288, 2013
2D8Z	Solution structure of the third LIM domain of Four and a half LIM domains protein 2 (FHL-2) 分子名称: Four and a half LIM domains 2, ZINC ION 著者 Qin, X.R, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-12-08 公開日 2006-06-08 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the third LIM domain of Four and a half LIM domains protein 2 (FHL-2) To be published
4HB3	Crystal structure of CRM1(T539S)-Ran-RanBP1 with weakly bound unmodeled Leptomycin B 分子名称: CHLORIDE ION, Exportin-1, GTP-binding nuclear protein Ran, ... 著者 Sun, Q, Chook, Y.M. 登録日 2012-09-27 公開日 2013-01-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1. Proc.Natl.Acad.Sci.USA, 110, 2013
4HBX	Crystal Structure of the first bromodomain of human BRD4 in complex with a quinazolin ligand 分子名称: 3-methyl-6-(pyrrolidin-1-ylsulfonyl)-3,4-dihydroquinazolin-2(1H)-one, Bromodomain-containing protein 4 著者 Filippakopoulos, P, Picaud, S, Qi, J, Felletar, I, von Delft, F, Bountra, C, Arrowsmith, C.H, Edwards, A, Fish, P.V, Bunnage, M.E, Cook, A.S, Owen, D.R, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2012-09-28 公開日 2012-10-31 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Identification of a Chemical Probe for Bromo and Extra C-Terminal Bromodomain Inhibition through Optimization of a Fragment-Derived Hit. J.Med.Chem., 55, 2012

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