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7T12
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Hexameric HIV-1 (O-group) CA
分子名称: Capsid protein p24
著者Jacques, D.A, James, L.C.
登録日2021-12-01
公開日2022-10-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Evasion of cGAS and TRIM5 defines pandemic HIV.
Nat Microbiol, 7, 2022
7T15
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Hexameric SIVcpz CA
分子名称: Capsid protein p24
著者Jacques, D.A, Dickson, C.F, James, L.C.
登録日2021-12-01
公開日2022-10-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Evasion of cGAS and TRIM5 defines pandemic HIV.
Nat Microbiol, 7, 2022
2YW4
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BU of 2yw4 by Molmil
Crystal Structure Analysis of the 4-hydroxy-2-oxoglutarate aldolase/2-deydro-3-deoxyphosphogluconate aldolase from TTHB1
分子名称: 4-hydroxy-2-oxoglutarate aldolase/2-deydro-3-deoxyphosphogluconate aldolase
著者Kawano, Y, Hashimoto, K, Kamiya, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-04-19
公開日2007-10-23
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Crystal Structure Analysis of the 4-hydroxy-2-oxoglutarate aldolase/2-deydro-3-deoxyphosphogluconate aldolase from TTHB1
To be published
7TBA
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BU of 7tba by Molmil
Pentraxin - ligand complex
分子名称: C-reactive protein, CALCIUM ION, [3-(dibutylamino)propyl]phosphonic acid
著者Shing, K.S.C.T, Morton, C.J, Parker, M.W.
登録日2021-12-21
公開日2022-10-19
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献A novel phosphocholine-mimetic inhibits a pro-inflammatory conformational change in C-reactive protein.
Embo Mol Med, 15, 2023
2OCJ
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BU of 2ocj by Molmil
Human p53 core domain in the absence of DNA
分子名称: P53 TUMOR SUPPRESSOR, ZINC ION
著者Wang, Y, Rosengarth, A, Luecke, H.
登録日2006-12-20
公開日2007-03-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structure of the human p53 core domain in the absence of DNA.
Acta Crystallogr.,Sect.D, 63, 2007
3JAK
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BU of 3jak by Molmil
Cryo-EM structure of GTPgammaS-microtubule co-polymerized with EB3 (merged dataset with and without kinesin bound)
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Zhang, R, Nogales, E.
登録日2015-06-16
公開日2015-08-12
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Mechanistic Origin of Microtubule Dynamic Instability and Its Modulation by EB Proteins.
Cell(Cambridge,Mass.), 162, 2015
2YE0
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BU of 2ye0 by Molmil
X-ray structure of the cyan fluorescent protein mTurquoise (K206A mutant)
分子名称: GREEN FLUORESCENT PROTEIN
著者von Stetten, D, Goedhart, J, Noirclerc-Savoye, M, Lelimousin, M, Joosen, L, Hink, M.A, van Weeren, L, Gadella, T.W.J, Royant, A.
登録日2011-03-25
公開日2012-03-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Structure-Guided Evolution of Cyan Fluorescent Proteins Towards a Quantum Yield of 93%
Nat.Commun, 3, 2012
5M6B
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BU of 5m6b by Molmil
structure of recombinant mushroom tyrosinase (abPPO4)
分子名称: COPPER (II) ION, OXYGEN ATOM, Polyphenol oxidase 4
著者Pretzler, M, Bijelic, A, Rompel, A.
登録日2016-10-24
公開日2017-05-17
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Heterologous expression and characterization of functional mushroom tyrosinase (AbPPO4).
Sci Rep, 7, 2017
7EB6
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Crystal structure of GTP-binding protein-like domain of AGAP1
分子名称: Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1
著者Cheng, N, Zhang, H, Zhang, S, Ma, X, Meng, G.
登録日2021-03-09
公開日2021-04-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.014 Å)
主引用文献Crystal structure of the GTP-binding protein-like domain of AGAP1.
Acta Crystallogr.,Sect.F, 77, 2021
5M75
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Cocrystal structure of cAMP-dependent Protein Kinase (PKA) in complex with a (S)-methyl substitued Fasudil-derivative
分子名称: 5-[[(2~{S})-2-methyl-1,4-diazepan-1-yl]sulfonyl]isoquinoline, DIMETHYL SULFOXIDE, cAMP-dependent protein kinase catalytic subunit alpha, ...
著者Wienen-Schmidt, B, Heine, A, Klebe, G.
登録日2016-10-26
公開日2018-06-06
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.538 Å)
主引用文献Cocrystal structure of cAMP-dependent Protein Kinase (PKA) in complex with differently methylated Fasudil-derived ligands.
To be Published
2YWY
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BU of 2ywy by Molmil
Structure of new antigen receptor variable domain from sharks
分子名称: new antigen receptor variable domain
著者Streltsov, V.A.
登録日2007-04-23
公開日2007-10-30
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Shark IgNAR antibody mimotopes target a murine immunoglobulin through extended CDR3 loop structures
Proteins, 71, 2007
2ODN
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BU of 2odn by Molmil
MSRECA-dATP complex
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Protein recA
著者Krishna, R, Rajan Prabu, J, Manjunath, G.P, Datta, S, Chandra, N.R, Muniyappa, K, Vijayan, M.
登録日2006-12-24
公開日2007-06-19
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Snapshots of RecA protein involving movement of the C-domain and different conformations of the DNA-binding loops: crystallographic and comparative analysis of 11 structures of Mycobacterium smegmatis RecA
J.Mol.Biol., 367, 2007
6ZPG
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BU of 6zpg by Molmil
Kinesin binding protein (KBP)
分子名称: KIF-binding protein
著者Atherton, J, Hummel, J.J.A, Olieric, N, Locke, J, Pena, A, Rosenfeld, S.S, Steinmetz, M.O, Hoogenraad, C.C, Moores, C.A.
登録日2020-07-08
公開日2020-12-30
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献The mechanism of kinesin inhibition by kinesin-binding protein.
Elife, 9, 2020
8R41
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BU of 8r41 by Molmil
Structure of CHI3L1 in complex with inhibitor 1
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BROMIDE ION, ...
著者Nowak, E, Napiorkowska-Gromadzka, A, Nowotny, M.
登録日2023-11-10
公開日2024-03-13
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structure-Based Discovery of High-Affinity Small Molecule Ligands and Development of Tool Probes to Study the Role of Chitinase-3-Like Protein 1.
J.Med.Chem., 67, 2024
2JWP
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BU of 2jwp by Molmil
Malectin
分子名称: Malectin
著者Schallus, T, Muhle-goll, C.
登録日2007-10-23
公開日2008-08-12
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Malectin: A Novel Carbohydrate-binding Protein of the Endoplasmic Reticulum and a Candidate Player in the Early Steps of Protein N-Glycosylation
Mol.Cell.Biol., 19, 2008
3K9X
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BU of 3k9x by Molmil
X-ray crystal structure of human fxa in complex with (S)-N-((2-METHYLBENZOFURAN-5-YLAMINO)(2-OXO-1-(2-OXO-2- (PYRROLIDIN-1-YL)ETHYL)AZEPAN-3- YLAMINO)METHYLENE)NICOTINAMIDE
分子名称: CALCIUM ION, GLYCEROL, N-{N'-(2-methyl-1-benzofuran-5-yl)-N-[(3S)-2-oxo-1-(2-oxo-2-pyrrolidin-1-ylethyl)azepan-3-yl]carbamimidoyl}pyridine-3-carboxamide, ...
著者Klei, H.E, Kish, K, Ghosh, K, Rushith, A.
登録日2009-10-16
公開日2009-12-15
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Aroylguanidine-based factor Xa inhibitors: the discovery of BMS-344577
Bioorg.Med.Chem.Lett., 19, 2009
7T14
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Hexameric SIVmac CA
分子名称: Capsid protein p24
著者Jacques, D.A, James, L.C.
登録日2021-12-01
公開日2022-10-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Evasion of cGAS and TRIM5 defines pandemic HIV.
Nat Microbiol, 7, 2022
6ZPJ
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BU of 6zpj by Molmil
Crystal structure of the unconventional kinetochore protein Leishmania mexicana KKT4 coiled coil domain
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, IMIDAZOLE, Leishmania mexicana KKT4
著者Ludzia, P, Lowe, E.D, Marciano, G, Mohammed, S, Redfield, C, Akiyoshi, B.
登録日2020-07-08
公開日2020-10-21
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural characterization of KKT4, an unconventional microtubule-binding kinetochore protein.
Structure, 29, 2021
6ZPM
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Crystal structure of the unconventional kinetochore protein Trypanosoma cruzi KKT4 coiled coil domain
分子名称: THREONINE, Trypanosoma cruzi KKT4 117-218
著者Ludzia, P, Lowe, D.E, Marciano, G, Mohammed, S, Redfield, C, Akiyoshi, B.
登録日2020-07-08
公開日2020-10-21
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural characterization of KKT4, an unconventional microtubule-binding kinetochore protein.
Structure, 29, 2021
7E81
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Cryo-EM structure of the flagellar MS ring with FlgB-Dc loop and FliE-helix 1 from Salmonella
分子名称: Flagellar M-ring protein, FlgB-Dc loop, FliE helix 1
著者Tan, J.X, Chang, S.H, Wang, X.F, Xu, C.H, Zhou, Y, Zhang, X, Zhu, Y.Q.
登録日2021-02-28
公開日2021-04-28
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structural basis of assembly and torque transmission of the bacterial flagellar motor.
Cell, 184, 2021
5LKH
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Cryo-EM structure of the Tc toxin TcdA1 in its pore state (obtained by flexible fitting)
分子名称: TcdA1
著者Gatsogiannis, C, Merino, F, Prumbaum, D, Roderer, D, Leidreiter, F, Meusch, D, Raunser, S.
登録日2016-07-22
公開日2016-08-31
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.46 Å)
主引用文献Membrane insertion of a Tc toxin in near-atomic detail.
Nat.Struct.Mol.Biol., 23, 2016
2YLR
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BU of 2ylr by Molmil
SNAPSHOTS OF ENZYMATIC BAEYER-VILLIGER CATALYSIS: OXYGEN ACTIVATION AND INTERMEDIATE STABILIZATION: COMPLEX WITH NADP
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PHENYLACETONE MONOOXYGENASE
著者Orru, R, Dudek, H.M, Martinoli, C, Torres Pazmino, D.E, Royant, A, Weik, M, Fraaije, M.W, Mattevi, A.
登録日2011-06-06
公開日2011-06-22
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Snapshots of Enzymatic Baeyer-Villiger Catalysis: Oxygen Activation and Intermediate Stabilization.
J.Biol.Chem., 286, 2011
6ZRR
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three-protofilament amyloid structure of S20G variant of human amylin (IAPP - Islet Amyloid Polypeptide)
分子名称: Islet amyloid polypeptide
著者Gallardo, R.U, Iadanza, M.G, Ranson, N.A, Radford, S.E.
登録日2020-07-14
公開日2020-09-30
最終更新日2020-11-18
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Fibril structures of diabetes-related amylin variants reveal a basis for surface-templated assembly.
Nat.Struct.Mol.Biol., 27, 2020
3J7H
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Structure of beta-galactosidase at 3.2-A resolution obtained by cryo-electron microscopy
分子名称: Beta-galactosidase, MAGNESIUM ION
著者Bartesaghi, A, Matthies, D, Banerjee, S, Merk, A, Subramaniam, S.
登録日2014-06-30
公開日2014-07-30
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure of beta-galactosidase at 3.2- angstrom resolution obtained by cryo-electron microscopy.
Proc.Natl.Acad.Sci.USA, 111, 2014
6ZS2
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Crystal Structure of the bromodomain of human transcription activator BRG1 (SMARCA4) in complex with 2-(6-amino-5-(piperazin-1-yl)pyridazin-3-yl)phenol
分子名称: 1,2-ETHANEDIOL, 2-(6-azanyl-5-piperazin-4-ium-1-yl-pyridazin-3-yl)phenol, Transcription activator BRG1
著者Preuss, F, Joerger, A.C, Kraemer, A, Wanior, M, Knapp, S, Structural Genomics Consortium (SGC)
登録日2020-07-15
公開日2020-10-07
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Pan-SMARCA/PB1 Bromodomain Inhibitors and Their Role in Regulating Adipogenesis.
J.Med.Chem., 63, 2020

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