PDB: 5653 件ウェブページステータス検索Chemie searchBIRD

---

2RB8	High resolution design of a protein loop 分子名称: Tenascin 著者 Hu, X, Wang, H, Ke, H, Kuhlman, B. 登録日 2007-09-18 公開日 2007-11-20 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 High-resolution design of a protein loop. Proc.Natl.Acad.Sci.Usa, 104, 2007
3VBT	Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design 分子名称: 4-chloro-2-(1H-pyrazol-3-yl)phenol, Serine/threonine-protein kinase pim-1 著者 Liu, J. 登録日 2012-01-02 公開日 2012-03-21 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 Implications of promiscuous Pim-1 kinase fragment inhibitor hydrophobic interactions for fragment-based drug design. J.Med.Chem., 55, 2012
6LDW	Structure of antibody C9 in complex with methylated peptide 分子名称: CHLORIDE ION, Fab heavy chain, Fab light chain, ... 著者 Caaveiro, J.M.M, Tsumoto, K. 登録日 2019-11-23 公開日 2020-11-25 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural basis for antigen recognition by methylated lysine-specific antibodies. J.Biol.Chem., 296, 2020
3VC4	Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design 分子名称: (5Z)-5-[3-(trifluoromethyl)benzylidene]-1,3-thiazolidine-2,4-dione, IMIDAZOLE, Serine/threonine-protein kinase pim-1 著者 Liu, J. 登録日 2012-01-03 公開日 2012-03-21 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 Implications of promiscuous Pim-1 kinase fragment inhibitor hydrophobic interactions for fragment-based drug design. J.Med.Chem., 55, 2012
6OV9	Coiled-coil Trimer with Glu:p-nitrophenylalanine:Lys Triad 分子名称: Coiled-coil Trimer with Glu:p-nitrophenylalanine:Lys Triad 著者 Smith, M.S, Stern, K.L, Billings, W.M, Price, J.L. 登録日 2019-05-07 公開日 2020-04-29 最終更新日 2020-05-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Context-Dependent Stabilizing Interactions among Solvent-Exposed Residues along the Surface of a Trimeric Helix Bundle. Biochemistry, 59, 2020
6OVS	Coiled-coil Trimer with Glu:Tyr:Lys Triad 分子名称: Coiled-coil Trimer with Glu:Tyr:Lys Triad, PENTAETHYLENE GLYCOL 著者 Smith, M.S, Stern, K.L, Billings, W.M, Price, J.L. 登録日 2019-05-08 公開日 2020-04-29 最終更新日 2020-05-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Context-Dependent Stabilizing Interactions among Solvent-Exposed Residues along the Surface of a Trimeric Helix Bundle. Biochemistry, 59, 2020
6LDV	Structure antibody F9 in complex with methylated peptide 分子名称: Fab heavy chain, Fab light chain, GLY-M3L-GLY-GLY-THR-TYR-PRO, ... 著者 Caaveiro, J.M.M, Tsumoto, K. 登録日 2019-11-23 公開日 2020-11-25 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural basis for antigen recognition by methylated lysine-specific antibodies. J.Biol.Chem., 296, 2020
6OSD	Coiled-coil Trimer with Glu:Phe:Lys Triad 分子名称: Coiled-coil Trimer with Glu:Phe:Lys Triad 著者 Smith, M.S, Stern, K.L, Billings, W.M, Price, J.L. 登録日 2019-05-01 公開日 2020-04-29 最終更新日 2020-05-20 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Context-Dependent Stabilizing Interactions among Solvent-Exposed Residues along the Surface of a Trimeric Helix Bundle. Biochemistry, 59, 2020
6OLO	Controlling the Self-Assembly of Synthetic Metal-Coordinating Coiled-Coil Peptides: Hexagonal Lattice from a Trimeric Coiled Coil 分子名称: COPPER (II) ION, Designed trimeric coiled coil peptide 著者 Schieb, K.A, Horne, W.S. 登録日 2019-04-16 公開日 2020-03-25 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Understanding and controlling the metal-directed assembly of terpyridine-functionalized coiled-coil peptides. Chem.Commun.(Camb.), 55, 2019
2RLZ	Solid-State MAS NMR structure of the dimer Crh 分子名称: HPr-like protein crh 著者 Loquet, A, Bardiaux, B, Gardiennet, C, Blanchet, C, Baldus, M, Nilges, M, Malliavin, T, Bockmann, A. 登録日 2007-09-04 公開日 2008-06-17 最終更新日 2024-05-29 実験手法 SOLID-STATE NMR 主引用文献 3D structure determination of the Crh protein from highly ambiguous solid-state NMR restraints. J.Am.Chem.Soc., 130, 2008
3VBV	Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design 分子名称: 8-hydroxyquinoline-2-carboxamide, Serine/threonine-protein kinase pim-1 著者 Liu, J. 登録日 2012-01-02 公開日 2012-03-21 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Implications of promiscuous Pim-1 kinase fragment inhibitor hydrophobic interactions for fragment-based drug design. J.Med.Chem., 55, 2012
6OVV	Coiled-coil Trimer with Glu:4-pyridinylalanine:Lys Triad 分子名称: Coiled-coil Trimer with Glu:4-pyridinylalanine:Lys Triad 著者 Smith, M.S, Stern, K.L, Billings, W.M, Price, J.L. 登録日 2019-05-08 公開日 2020-04-29 最終更新日 2020-05-20 実験手法 X-RAY DIFFRACTION (2.201 Å) 主引用文献 Context-Dependent Stabilizing Interactions among Solvent-Exposed Residues along the Surface of a Trimeric Helix Bundle. Biochemistry, 59, 2020
3VBQ	Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design 分子名称: (5~{Z})-5-[[3-[6-[(4-azanylcyclohexyl)amino]pyrazin-2-yl]phenyl]methylidene]-1,3-thiazolidine-2,4-dione, Serine/threonine-protein kinase pim-1 著者 Liu, J. 登録日 2012-01-02 公開日 2012-03-21 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Implications of promiscuous Pim-1 kinase fragment inhibitor hydrophobic interactions for fragment-based drug design. J.Med.Chem., 55, 2012
7YTO	The Crystal Structure Analysis of Creatine Amidinohydrolase from Alcaligenes sp. KS-85 分子名称: Creatine amidinohydrolase 著者 Chen, R.S. 登録日 2022-08-15 公開日 2023-08-23 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Creatinase: Using Increased Entropy to Improve the Activity and Thermostability. J.Phys.Chem.B, 127, 2023
3VBY	Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design 分子名称: IMIDAZOLE, Serine/threonine-protein kinase pim-1, furan-2-yl(1H-indol-3-yl)methanone 著者 Liu, J. 登録日 2012-01-02 公開日 2012-03-21 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Implications of promiscuous Pim-1 kinase fragment inhibitor hydrophobic interactions for fragment-based drug design. J.Med.Chem., 55, 2012
5I8B	CBP in complex with Cpd23 ((R)-6-(3-(benzyloxy)phenyl)-4-methyl-1,3,4,5-tetrahydro-2H-benzo[b][1,4]diazepin-2-one) 分子名称: (4R)-6-[3-(benzyloxy)phenyl]-4-methyl-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one, 1,2-ETHANEDIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... 著者 Murray, J.M. 登録日 2016-02-18 公開日 2016-04-20 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.5218 Å) 主引用文献 Fragment-Based Discovery of a Selective and Cell-Active Benzodiazepinone CBP/EP300 Bromodomain Inhibitor (CPI-637). Acs Med.Chem.Lett., 7, 2016
6LRB	The A form apo structure of NrS-1 C terminal region-CTR 分子名称: MAGNESIUM ION, Primase 著者 Chen, X, Gan, J. 登録日 2020-01-15 公開日 2020-04-08 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structural studies reveal a ring-shaped architecture of deep-sea vent phage NrS-1 polymerase. Nucleic Acids Res., 48, 2020
6LT0	cryo-EM structure of C9ORF72-SMCR8-WDR41 分子名称: Guanine nucleotide exchange C9orf72, Guanine nucleotide exchange protein SMCR8, WD repeat-containing protein 41 著者 Tang, D, Sheng, J, Xu, L, Zhan, X, Yan, C, Qi, S. 登録日 2020-01-21 公開日 2020-04-15 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Cryo-EM structure of C9ORF72-SMCR8-WDR41 reveals the role as a GAP for Rab8a and Rab11a. Proc.Natl.Acad.Sci.USA, 117, 2020
7Q3K	Computationally designed thioredoxin subjected to stability optimizing mutations. 分子名称: SULFATE ION, eMM9 著者 Norrild, R.K, Johansson, K.E, O'Shea, C, Lindorff-Larsen, K, Winther, J.R, Morth, J.P. 登録日 2021-10-27 公開日 2022-11-16 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Increasing protein stability by inferring substitution effects from high-throughput experiments. Cell Rep Methods, 2, 2022
4V7Q	Atomic model of an infectious rotavirus particle 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Core scaffold protein, ... 著者 Settembre, E.C, Chen, J.Z, Dormitzer, P.R, Grigorieff, N, Harrison, S.C. 登録日 2010-05-13 公開日 2014-07-09 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Atomic model of an infectious rotavirus particle. Embo J., 30, 2011
6M2V	Crystal structure of UHRF1 SRA complexed with fully-mCHG DNA. 分子名称: DNA (5'-D(*TP*CP*AP*CP*GP*(5CM)P*TP*GP*CP*GP*TP*GP*A)-3'), E3 ubiquitin-protein ligase UHRF1 著者 Abhishek, S, Nakarakanti, N.K, Deeksha, W, Rajakumara, E. 登録日 2020-03-01 公開日 2021-01-13 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Mechanistic insights into recognition of symmetric methylated cytosines in CpG and non-CpG DNA by UHRF1 SRA. Int.J.Biol.Macromol., 170, 2021
6PA7	The cryo-EM structure of the human DNMT3A2-DNMT3B3 complex bound to nucleosome. 分子名称: CHLORIDE ION, DNA (167-MER), DNA (cytosine-5)-methyltransferase 3A, ... 著者 Xu, T.H, Liu, M, Zhou, X.E, Liang, G, Zhao, G, Xu, H.E, Melcher, K, Jones, P.A. 登録日 2019-06-11 公開日 2020-06-17 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (2.94 Å) 主引用文献 Structure of nucleosome-bound DNA methyltransferases DNMT3A and DNMT3B. Nature, 586, 2020
6G65	Crystal structure of a parallel six-helix coiled coil CC-Type2-VV 分子名称: CC-Type2-VV 著者 Rhys, G.G, Brady, R.L, Woolfson, D.N. 登録日 2018-04-01 公開日 2018-10-17 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Maintaining and breaking symmetry in homomeric coiled-coil assemblies. Nat Commun, 9, 2018
6G6C	Crystal structure of a parallel six-helix coiled coil CC-Type2-LL-L17E 分子名称: CC-Type2-LL-L17E 著者 Rhys, G.G, Brady, R.L, Woolfson, D.N. 登録日 2018-04-01 公開日 2018-10-17 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Maintaining and breaking symmetry in homomeric coiled-coil assemblies. Nat Commun, 9, 2018
6FP9	Crystal structure of anti-mTFP1 DARPin 1238_E11 分子名称: 1,2-ETHANEDIOL, DARPin 1238_E11, SULFATE ION 著者 Jakob, R.P, Vigano, M.A, Bieli, D, Matsuda, S, Schaefer, J.V, Pluckthun, A, Affolter, M, Maier, T. 登録日 2018-02-09 公開日 2018-10-03 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 DARPins recognizing mTFP1 as novel reagents forin vitroandin vivoprotein manipulations. Biol Open, 7, 2018

<125126127128129130131132133134135136137138139140>