2C2W
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2C2X
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2C2Y
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2C2Z
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![BU of 2c2z by Molmil](/molmil-images/mine/2c2z) | Crystal structure of caspase-8 in complex with aza-peptide Michael acceptor inhibitor | 分子名称: | AZA-PEPTIDE INHIBITOR (5S, 8R, 11S)-8-(2-CARBOXYETHYL) -14-[4-(3,4-DIHYDROQUINOLIN-1(2H)-YL)-4-OXOBUTANOYL] -11-[(1R)-1-HYDROXYETHYL]-5-(2-METHYLPROPYL)-3,6,9,12-TETRAOXO -1-PHENYL-2-OXA-4,7,10,13,14-PENTAAZAHEXADECAN-16-OIC ACID, ... | 著者 | Ganesan, R, Jelakovic, S, Ekici, O.D, Li, Z.Z, James, K.E, Asgian, J.L, Campbell, A.J, Mikolajczyk, J, Salvesen, G.S, Powers, J.C, Gruetter, M.G. | 登録日 | 2005-10-02 | 公開日 | 2006-09-20 | 最終更新日 | 2017-02-08 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Design, Synthesis, and Evaluation of Aza-Peptide Michael Acceptors as Selective and Potent Inhibitors of Caspases-2, -3, -6, -7, -8, -9, and - 10. J.Med.Chem., 49, 2006
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2C30
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![BU of 2c30 by Molmil](/molmil-images/mine/2c30) | Crystal Structure Of The Human P21-Activated Kinase 6 | 分子名称: | CHLORIDE ION, PHOSPHATE ION, SERINE/THREONINE-PROTEIN KINASE PAK 6 | 著者 | Filippakopoulos, P, Berridge, G, Bray, J, Burgess, N, Colebrook, S, Das, S, Eswaran, J, Gileadi, O, Papagrigoriou, E, Savitsky, P, Smee, C, Turnbull, A, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A, von Delft, F, Knapp, S. | 登録日 | 2005-10-02 | 公開日 | 2006-02-08 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal Structures of the P21-Activated Kinases Pak4, Pak5, and Pak6 Reveal Catalytic Domain Plasticity of Active Group II Paks. Structure, 15, 2007
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2C31
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![BU of 2c31 by Molmil](/molmil-images/mine/2c31) | CRYSTAL STRUCTURE OF OXALYL-COA DECARBOXYLASE IN COMPLEX WITH THE COFACTOR DERIVATIVE THIAMIN-2-THIAZOLONE DIPHOSPHATE AND ADENOSINE DIPHOSPHATE | 分子名称: | 2-{3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-4-METHYL-2-OXO-2,3-DIHYDRO-1,3-THIAZOL-5-YL}ETHYL TRIHYDROGEN DIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Berthold, C.L, Moussatche, P, Richards, N.G.J, Lindqvist, Y. | 登録日 | 2005-10-03 | 公開日 | 2005-10-07 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Structural Basis for Activation of the Thiamin Diphosphate-Dependent Enzyme Oxalyl-Coa Decarboxylase by Adenosine Diphosphate. J.Biol.Chem., 280, 2005
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2C32
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2C34
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![BU of 2c34 by Molmil](/molmil-images/mine/2c34) | Leishmania mexicana ICP | 分子名称: | INHIBITOR OF CYSTEINE PEPTIDASES | 著者 | Smith, B.O, Picken, N.C, Bromek, K, Westrop, G.D, Mottram, J.C, Coombs, G.H. | 登録日 | 2005-10-04 | 公開日 | 2005-12-21 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | The Structure of Leishmania Mexicana Icp Provides Evidence for Convergent Evolution of Cysteine Peptidase Inhibitors. J.Biol.Chem., 281, 2006
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2C35
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![BU of 2c35 by Molmil](/molmil-images/mine/2c35) | Subunits Rpb4 and Rpb7 of human RNA polymerase II | 分子名称: | DNA-DIRECTED RNA POLYMERASE II 16 KDA POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 19 KDA POLYPEPTIDE | 著者 | Meka, H, Werner, F, Cordell, S.C, Onesti, S, Brick, P. | 登録日 | 2005-10-04 | 公開日 | 2005-11-18 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal Structure and RNA Binding of the Rpb4/Rpb7 Subunits of Human RNA Polymerase II. Nucleic Acids Res., 33, 2005
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2C36
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![BU of 2c36 by Molmil](/molmil-images/mine/2c36) | Structure of unliganded HSV gD reveals a mechanism for receptor- mediated activation of virus entry | 分子名称: | CHLORIDE ION, GLYCOPROTEIN D HSV-1, ZINC ION, ... | 著者 | Krummenacher, C, Supekar, V.M, Whitbeck, J.C, Lazear, E, Connolly, S.A, Eisenberg, R.J, Cohen, G.H, Wiley, D.C, Carfi, A. | 登録日 | 2005-10-04 | 公開日 | 2005-11-23 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Structure of unliganded HSV gD reveals a mechanism for receptor-mediated activation of virus entry. EMBO J., 24, 2005
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2C37
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2C38
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2C39
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2C3A
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![BU of 2c3a by Molmil](/molmil-images/mine/2c3a) | Structure of unliganded HSV gD reveals a mechanism for receptor- mediated activation of virus entry | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCOPROTEIN D, ... | 著者 | Krummenacher, C, Supekar, V.M, Whitbeck, J.C, Lazear, E, Connolly, S.A, Eisenberg, R.J, Cohen, G.H, Wiley, D.C, Carfi, A. | 登録日 | 2005-10-05 | 公開日 | 2005-12-21 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure of Unliganded Hsv Gd Reveals a Mechanism for Receptor-Mediated Activation of Virus Entry. Embo J., 24, 2005
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2C3B
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![BU of 2c3b by Molmil](/molmil-images/mine/2c3b) | The Crystal Structure of Aspergillus fumigatus Cyclophilin reveals 3D Domain Swapping of a Central Element | 分子名称: | PPIASE, SULFATE ION | 著者 | Limacher, A, Kloer, D.P, Fluckiger, S, Folkers, G, Crameri, R, Scapozza, L. | 登録日 | 2005-10-05 | 公開日 | 2006-01-30 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | The Crystal Structure of Aspergillus Fumigatus Cyclophilin Reveals 3D Domain Swapping of a Central Element Structure, 14, 2006
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2C3C
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![BU of 2c3c by Molmil](/molmil-images/mine/2c3c) | 2.01 Angstrom X-ray crystal structure of a mixed disulfide between coenzyme M and NADPH-dependent oxidoreductase 2-ketopropyl coenzyme M carboxylase | 分子名称: | 1-THIOETHANESULFONIC ACID, 2-OXOPROPYL-COM REDUCTASE, ACETONE, ... | 著者 | Pandey, A.S, Nocek, B, Clark, D.D, Ensign, S.A, Peters, J.W. | 登録日 | 2005-10-05 | 公開日 | 2005-12-12 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Mechanistic Implications of the Structure of the Mixed-Disulfide Intermediate of the Disulfide Oxidoreductase, 2-Ketopropyl-Coenzyme M Oxidoreductase/Carboxylase. Biochemistry, 45, 2006
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2C3D
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![BU of 2c3d by Molmil](/molmil-images/mine/2c3d) | 2.15 Angstrom crystal structure of 2-ketopropyl coenzyme M oxidoreductase carboxylase with a coenzyme M disulfide bound at the active site | 分子名称: | 1-THIOETHANESULFONIC ACID, 2-OXOPROPYL-COM REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE | 著者 | Pandey, A.S, Nocek, B, Clark, D.D, Ensign, S.A, Peters, J.W. | 登録日 | 2005-10-05 | 公開日 | 2005-11-07 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Mechanistic Implications of the Structure of the Mixed-Disulfide Intermediate of the Disulfide Oxidoreductase, 2-Ketopropyl-Coenzyme M Oxidoreductase/Carboxylase. Biochemistry, 45, 2006
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2C3E
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![BU of 2c3e by Molmil](/molmil-images/mine/2c3e) | The bovine mitochondrial ADP-ATP carrier | 分子名称: | ADP/ATP TRANSLOCASE 1, CARDIOLIPIN, Carboxyatractyloside | 著者 | Nury, H, Dahout-Gonzalez, C, Trezeguet, V, Lauquin, G, Brandolin, G, Pebay-Peyroula, E. | 登録日 | 2005-10-06 | 公開日 | 2005-10-20 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural Basis for Lipid-Mediated Interactions between Mitochondrial Adp/ATP Carrier Monomers. FEBS Lett., 579, 2005
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2C3F
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![BU of 2c3f by Molmil](/molmil-images/mine/2c3f) | The structure of a group A streptococcal phage-encoded tail-fibre showing hyaluronan lyase activity. | 分子名称: | HYALURONIDASE, PHAGE ASSOCIATED, SODIUM ION | 著者 | Taylor, E.J, Smith, N.L, Linsay, A.-M, Charnock, S.J, Turkenburg, J.P, Dodson, E.J, Davies, G.J, Black, G.W. | 登録日 | 2005-10-06 | 公開日 | 2005-11-29 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | Structure of a Group a Streptococcal Phage-Encoded Virulence Factor Reveals Catalytically Active Triple-Stranded Beta-Helix Proc.Natl.Acad.Sci.USA, 102, 2005
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2C3G
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![BU of 2c3g by Molmil](/molmil-images/mine/2c3g) | Structure of CBM26 from Bacillus halodurans amylase | 分子名称: | ALPHA-AMYLASE G-6, CADMIUM ION | 著者 | Boraston, A.B, Healey, M, Klassen, J, Ficko-Blean, E, Lammerts Van Bueren, A, Law, V. | 登録日 | 2005-10-07 | 公開日 | 2005-10-17 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A Structural and Functional Analysis of Alpha-Glucan Recognition by Family 25 and 26 Carbohydrate-Binding Modules Reveals a Conserved Mode of Starch Recognition J.Biol.Chem., 281, 2006
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2C3H
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![BU of 2c3h by Molmil](/molmil-images/mine/2c3h) | Structure of CBM26 from Bacillus halodurans amylase in complex with maltose | 分子名称: | ALPHA-AMYLASE G-6, SULFATE ION, alpha-D-glucopyranose, ... | 著者 | Boraston, A.B, Healey, M, Klassen, J, Ficko-Blean, E, Lammerts van Bueren, A, Law, V. | 登録日 | 2005-10-07 | 公開日 | 2005-10-17 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | A Structural and Functional Analysis of Alpha-Glucan Recognition by Family 25 and 26 Carbohydrate-Binding Modules Reveals a Conserved Mode of Starch Recognition J.Biol.Chem., 281, 2006
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2C3I
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![BU of 2c3i by Molmil](/molmil-images/mine/2c3i) | CRYSTAL STRUCTURE OF HUMAN PIM1 IN COMPLEX WITH IMIDAZOPYRIDAZIN I | 分子名称: | 1-(3-{6-[(CYCLOPROPYLMETHYL)AMINO]IMIDAZO[1,2-B]PYRIDAZIN-3-YL}PHENYL)ETHANONE, PIMTIDE, PROTO-ONCOGENE SERINE THREONINE PROTEIN KINASE PIM1 | 著者 | Philippakopoulos, P, Knapp, S, Debreczeni, J, Bullock, A, von Delft, F, Sundstrom, M, Arrowsmith, C, Edwards, A, Guo, K, Weigelt, J. | 登録日 | 2005-10-07 | 公開日 | 2005-11-01 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural Analysis Identifies Imidazo[1,2- B]Pyridazines as Pim Kinase Inhibitors with in Vitro Antileukemic Activity. Cancer Res., 67, 2007
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2C3J
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![BU of 2c3j by Molmil](/molmil-images/mine/2c3j) | Identification of a buried pocket for potent and selective inhibition of Chk1: prediction and verification | 分子名称: | DEBROMOHYMENIALDISINE, SERINE/THREONINE-PROTEIN KINASE CHK1, SULFITE ION | 著者 | Foloppe, N, Fisher, L.M, Francis, G, Howes, R, Kierstan, P, Potter, A. | 登録日 | 2005-10-10 | 公開日 | 2005-11-23 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Identification of a Buried Pocket for Potent and Selective Inhibition of Chk1: Prediction and Verification. Bioorg.Med.Chem., 14, 2006
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2C3K
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![BU of 2c3k by Molmil](/molmil-images/mine/2c3k) | Identification of a buried pocket for potent and selective inhibition of Chk1: prediction and verification | 分子名称: | 4-[3-(1H-BENZIMIDAZOL-2-YL)-1H-INDAZOL-6-YL]-2-METHOXYPHENOL, SERINE/THREONINE-PROTEIN KINASE CHK1 | 著者 | Foloppe, N, Fisher, L.M, Francis, G, Howes, R, Kierstan, P, Potter, A. | 登録日 | 2005-10-10 | 公開日 | 2005-11-23 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Identification of a Buried Pocket for Potent and Selective Inhibition of Chk1: Prediction and Verification. Bioorg.Med.Chem., 14, 2006
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2C3L
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![BU of 2c3l by Molmil](/molmil-images/mine/2c3l) | Identification of a buried pocket for potent and selective inhibition of Chk1: prediction and verification | 分子名称: | 3-(1H-BENZIMIDAZOL-2-YL)-1H-INDAZOLE, SERINE/THREONINE-PROTEIN KINASE CHK1, SULFATE ION | 著者 | Foloppe, N, Fisher, L.M, Francis, G, Howes, R, Kierstan, P, Potter, A. | 登録日 | 2005-10-10 | 公開日 | 2005-11-23 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Identification of a Buried Pocket for Potent and Selective Inhibition of Chk1: Prediction and Verification. Bioorg.Med.Chem., 14, 2006
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