2C3A

Structure of unliganded HSV gD reveals a mechanism for receptor- mediated activation of virus entry

Summary for 2C3A

Entry DOI	10.2210/pdb2c3a/pdb
Related	1JMA 1L2G 2C36
Descriptor	GLYCOPROTEIN D, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... (6 entities in total)
Functional Keywords	virus, herpes simplex virus, hsv-1, glycoprotein d, viral protein
Biological source	HUMAN HERPESVIRUS 1 (HUMAN HERPES SIMPLEX VIRUS 1)
Cellular location	Virion membrane; Single-pass type I membrane protein (By similarity): P57083
Total number of polymer chains	2
Total formula weight	64778.85
Authors	Krummenacher, C.,Supekar, V.M.,Whitbeck, J.C.,Lazear, E.,Connolly, S.A.,Eisenberg, R.J.,Cohen, G.H.,Wiley, D.C.,Carfi, A. (deposition date: 2005-10-05, release date: 2005-12-21, Last modification date: 2023-12-13)
Primary citation	Krummenacher, C.,Supekar, V.M.,Whitbeck, J.C.,Lazear, E.,Connolly, S.A.,Eisenberg, R.J.,Cohen, G.H.,Wiley, D.C.,Carfi, A. Structure of Unliganded Hsv Gd Reveals a Mechanism for Receptor-Mediated Activation of Virus Entry. Embo J., 24:4144-, 2005 Cited by PubMed: 16292345 DOI: 10.1038/SJ.EMBOJ.7600875 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation