2C3A
Structure of unliganded HSV gD reveals a mechanism for receptor- mediated activation of virus entry
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | GLYCOPROTEIN D | polymer | 286 | 31743.1 | 2 | UniProt (P57083) Pfam (PF01537) | HUMAN HERPESVIRUS 1 (HUMAN HERPES SIMPLEX VIRUS 1) | |
| 2 | C, D (C, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 3 | E, G (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 4 | F, J, K, L, M (A, B) | ZINC ION | non-polymer | 65.4 | 5 | Chemie (ZN) | |||
| 5 | H, I (B) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 6 | N, O (A, B) | water | water | 18.0 | 53 | Chemie (HOH) |
Sequence modifications
A, B: 22 - 307 (UniProt: P57083)
| PDB | External Database | Details |
|---|---|---|
| Cys 37 | Val 62 | engineered mutation |
| Cys 302 | Ala 327 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 63486.1 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 848.8 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 443.9 | |
| All* | Total formula weight | 64778.9 |
