2C0P
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![BU of 2c0p by Molmil](/molmil-images/mine/2c0p) | Aged form of mouse acetylcholinesterase inhibited by tabun | 分子名称: | ACETYLCHOLINESTERASE, ETHYL HYDROGEN PHOSPHONATE | 著者 | Ekstrom, F, Akfur, C, Tunemalm, A.-K, Lundberg, S. | 登録日 | 2005-09-07 | 公開日 | 2006-01-09 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural Changes of Phenylalanine 338 and Histidine 447 Revealed by the Crystal Structures of Tabun-Inhibited Murine Acetylcholinesterase. Biochemistry, 45, 2006
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2C0Q
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![BU of 2c0q by Molmil](/molmil-images/mine/2c0q) | non-aged form of mouse acetylcholinesterase inhibited by tabun | 分子名称: | ACETYLCHOLINESTERASE, HEXAETHYLENE GLYCOL, R-ETHYL N,N-DIMETHYLPHOSPHONAMIDATE | 著者 | Ekstrom, F, Akfur, C, Tunemalm, A.-K, Lundberg, S. | 登録日 | 2005-09-07 | 公開日 | 2006-01-09 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural Changes of Phenylalanine 338 and Histidine 447 Revealed by the Crystal Structures of Tabun-Inhibited Murine Acetylcholinesterase. Biochemistry, 45, 2006
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2C0R
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2C0S
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![BU of 2c0s by Molmil](/molmil-images/mine/2c0s) | NMR Solution Structure of a protein aspartic acid phosphate phosphatase from Bacillus Anthracis | 分子名称: | CONSERVED DOMAIN PROTEIN | 著者 | Grenha, R, Rzechorzek, N.J, Brannigan, J.A, Ab, E, Folkers, G.E, De Jong, R.N, Diercks, T, Wilkinson, A.J, Kaptein, R, Wilson, K.S. | 登録日 | 2005-09-07 | 公開日 | 2006-09-25 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural characterization of Spo0E-like protein-aspartic acid phosphatases that regulate sporulation in bacilli. J. Biol. Chem., 281, 2006
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2C0T
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![BU of 2c0t by Molmil](/molmil-images/mine/2c0t) | Src family kinase Hck with bound inhibitor A-641359 | 分子名称: | CALCIUM ION, N-(4-{4-AMINO-1-[1-(TETRAHYDRO-2H-PYRAN-4-YL)PIPERIDIN-4-YL]-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL}-2-METHOXYPHENYL)-1-METHYL-1H-INDOLE-2-CARBOXAMIDE, TYROSINE-PROTEIN KINASE HCK | 著者 | Borhani, D.W, Burchat, A, Calderwood, D.J, Hirst, G.C, Li, B, Loew, A. | 登録日 | 2005-09-07 | 公開日 | 2006-09-20 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Discovery of A-770041, a Src-Family Selective Orally Active Lck Inhibitor that Prevents Organ Allograft Rejection. Bioorg.Med.Chem.Lett., 16, 2006
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2C0U
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![BU of 2c0u by Molmil](/molmil-images/mine/2c0u) | Crystal Structure of a Covalent Complex of Nitroalkane Oxidase Trapped During Substrate Turnover | 分子名称: | (2S)-2-NITROBUTANE, FLAVIN-ADENINE DINUCLEOTIDE, NITROALKANE OXIDASE | 著者 | Nagpal, A, Valley, M.P, Fitzpatrick, P.F, Orville, A.M. | 登録日 | 2005-09-07 | 公開日 | 2006-02-01 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal Structures of Nitroalkane Oxidase: Insights Into the Reaction Mechanism from a Covalent Complex of the Flavoenzyme Trapped During Turnover. Biochemistry, 45, 2006
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2C0W
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![BU of 2c0w by Molmil](/molmil-images/mine/2c0w) | Molecular Structure of fd Filamentous Bacteriophage Refined with Respect to X-ray Fibre Diffraction | 分子名称: | COAT PROTEIN B | 著者 | Marvin, D.A, Welsh, L.C, Symmons, M.F, Scott, W.R.P, Straus, S.K. | 登録日 | 2005-09-08 | 公開日 | 2005-12-14 | 最終更新日 | 2024-02-14 | 実験手法 | FIBER DIFFRACTION (3.2 Å) | 主引用文献 | Molecular Structure of Fd (F1, M13) Filamentous Bacteriophage Refined with Respect to X-Ray Fibre Diffraction and Solid-State NMR Data Supports Specific Models of Phage Assembly at the Bacterial Membrane. J.Mol.Biol., 355, 2006
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2C0X
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![BU of 2c0x by Molmil](/molmil-images/mine/2c0x) | MOLECULAR STRUCTURE OF FD FILAMENTOUS BACTERIOPHAGE REFINED WITH RESPECT TO X-RAY FIBRE DIFFRACTION AND SOLID-STATE NMR DATA | 分子名称: | COAT PROTEIN B | 著者 | Marvin, D.A, Welsh, L.C, Symmons, M.F, Scott, W.R.P, Straus, S.K. | 登録日 | 2005-09-08 | 公開日 | 2005-12-14 | 最終更新日 | 2024-05-15 | 実験手法 | SOLID-STATE NMR | 主引用文献 | Molecular Structure of Fd (F1, M13) Filamentous Bacteriophage Refined with Respect to X-Ray Fibre Diffraction and Solid-State NMR Data Supports Specific Models of Phage Assembly at the Bacterial Membrane. J.Mol.Biol., 355, 2006
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2C0Y
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![BU of 2c0y by Molmil](/molmil-images/mine/2c0y) | THE CRYSTAL STRUCTURE OF A CYS25ALA MUTANT OF HUMAN PROCATHEPSIN S | 分子名称: | PROCATHEPSIN S | 著者 | Kaulmann, G, Palm, G.J, Schilling, K, Hilgenfeld, R, Wiederanders, B. | 登録日 | 2005-09-08 | 公開日 | 2006-11-08 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The Crystal Structure of a Cys25 -> Ala Mutant of Human Procathepsin S Elucidates Enzyme-Prosequence Interactions. Protein Sci., 15, 2006
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2C0Z
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![BU of 2c0z by Molmil](/molmil-images/mine/2c0z) | The 1.6 A resolution crystal structure of NovW: a 4-keto-6-deoxy sugar epimerase from the novobiocin biosynthetic gene cluster of Streptomyces spheroides | 分子名称: | 1,2-ETHANEDIOL, NOVW, SULFATE ION | 著者 | Jakimowicz, P, Tello, M, Freel-Meyers, C.L, Walsh, C.T, Buttner, M.J, Field, R.A, Lawson, D.M. | 登録日 | 2005-09-09 | 公開日 | 2006-01-25 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | The 1.6 A Resolution Crystal Structure of Novw: A 4-Keto-6-Deoxy Sugar Epimerase from the Novobiocin Biosynthetic Gene Cluster of Streptomyces Spheroides Proteins, 63, 2006
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2C10
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![BU of 2c10 by Molmil](/molmil-images/mine/2c10) | The structure of a truncated, soluble version of semicarbazide- sensitive amine oxidase | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Jakobsson, E, Kleywegt, G.J. | 登録日 | 2005-09-09 | 公開日 | 2006-09-20 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure of human semicarbazide-sensitive amine oxidase/vascular adhesion protein-1. Acta Crystallogr. D Biol. Crystallogr., 61, 2005
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2C11
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![BU of 2c11 by Molmil](/molmil-images/mine/2c11) | Crystal structure of the 2-hydrazinopyridine of semicarbazide- sensitive amine oxidase | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Jakobsson, E, Kleywegt, G.J. | 登録日 | 2005-09-09 | 公開日 | 2006-09-20 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure of human semicarbazide-sensitive amine oxidase/vascular adhesion protein-1. Acta Crystallogr. D Biol. Crystallogr., 61, 2005
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2C12
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![BU of 2c12 by Molmil](/molmil-images/mine/2c12) | Crystal Structure of Nitroalkane Oxidase in Complex with Spermine, a Competitive Inhibitor | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | 著者 | Nagpal, A, Valley, M.P, Fitzpatrick, P.F, Orville, A.M. | 登録日 | 2005-09-10 | 公開日 | 2006-02-01 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Crystal Structures of Nitroalkane Oxidase: Insights Into the Reaction Mechanism from a Covalent Complex of the Flavoenzyme Trapped During Turnover. Biochemistry, 45, 2006
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2C13
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![BU of 2c13 by Molmil](/molmil-images/mine/2c13) | 5-hydroxy-levulinic acid bound to Porphobilinogen synthase from Pseudomonas aeruginosa | 分子名称: | CHLORIDE ION, DELTA-AMINOLEVULINIC ACID DEHYDRATASE, DI(HYDROXYETHYL)ETHER, ... | 著者 | Frere, F, Nentwich, M, Gacond, S, Heinz, D.W, Neier, R, Frankenberg-Dinkel, N. | 登録日 | 2005-09-11 | 公開日 | 2006-06-20 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Probing the Active Site of Pseudomonas Aeruginosa Porphobilinogen Synthase Using Newly Developed Inhibitors. Biochemistry, 45, 2006
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2C14
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![BU of 2c14 by Molmil](/molmil-images/mine/2c14) | 5-(4-Carboxy-2-oxo-butylamino)-4-oxo-pentanoic acid acid bound to Porphobilinogen synthase from Pseudomonas aeruginosa | 分子名称: | DELTA-AMINOLEVULINIC ACID DEHYDRATASE, MAGNESIUM ION | 著者 | Frere, F, Nentwich, M, Gacond, S, Heinz, D.W, Neier, R, Frankenberg-Dinkel, N. | 登録日 | 2005-09-11 | 公開日 | 2006-06-20 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Probing the Active Site of Pseudomonas Aeruginosa Porphobilinogen Synthase Using Newly Developed Inhibitors. Biochemistry, 45, 2006
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2C15
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![BU of 2c15 by Molmil](/molmil-images/mine/2c15) | 5-(4-Carboxy-2-oxo-butoxy)-4-oxo-pentanoic acid acid bound to Porphobilinogen synthase from Pseudomonas aeruginosa | 分子名称: | DELTA-AMINOLEVULINIC ACID DEHYDRATASE, MAGNESIUM ION | 著者 | Frere, F, Nentwich, M, Gacond, S, Heinz, D.W, Neier, R, Frankenberg-Dinkel, N. | 登録日 | 2005-09-11 | 公開日 | 2006-06-20 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Probing the Active Site of Pseudomonas Aeruginosa Porphobilinogen Synthase Using Newly Developed Inhibitors. Biochemistry, 45, 2006
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2C16
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![BU of 2c16 by Molmil](/molmil-images/mine/2c16) | 5-(4-Carboxy-2-oxo-butane-1-sulfinyl)-4-oxo-pentanoic acid acid bound to Porphobilinogen synthase from Pseudomonas aeruginosa | 分子名称: | CHLORIDE ION, DELTA-AMINOLEVULINIC ACID DEHYDRATASE, DI(HYDROXYETHYL)ETHER, ... | 著者 | Frere, F, Nentwich, M, Gacond, S, Heinz, D.W, Neier, R, Frankenberg-Dinkel, N. | 登録日 | 2005-09-11 | 公開日 | 2006-06-20 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Probing the Active Site of Pseudomonas Aeruginosa Porphobilinogen Synthase Using Newly Developed Inhibitors. Biochemistry, 45, 2006
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2C18
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![BU of 2c18 by Molmil](/molmil-images/mine/2c18) | 5-(4-Carboxy-2-oxo-butane-1-sulfonyl)-4-oxo-pentanoic acid bound to Porphobilinogen synthase from Pseudomonas aeruginosa | 分子名称: | CHLORIDE ION, DELTA-AMINOLEVULINIC ACID DEHYDRATASE, MAGNESIUM ION, ... | 著者 | Frere, F, Nentwich, M, Gacond, S, Heinz, D.W, Neier, R, Frankenberg-Dinkel, N. | 登録日 | 2005-09-11 | 公開日 | 2006-06-20 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Probing the Active Site of Pseudomonas Aeruginosa Porphobilinogen Synthase Using Newly Developed Inhibitors. Biochemistry, 45, 2006
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2C19
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![BU of 2c19 by Molmil](/molmil-images/mine/2c19) | 5-(4-Carboxy-2-oxo-butylsulfanyl)-4-oxo-pentanoic acid acid bound to Porphobilinogen synthase from Pseudomonas aeruginosa | 分子名称: | DELTA-AMINOLEVULINIC ACID DEHYDRATASE, MAGNESIUM ION, SODIUM ION | 著者 | Frere, F, Nentwich, M, Gacond, S, Heinz, D.W, Neier, R, Frankenberg-Dinkel, N. | 登録日 | 2005-09-11 | 公開日 | 2006-06-20 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Probing the Active Site of Pseudomonas Aeruginosa Porphobilinogen Synthase Using Newly Developed Inhibitors. Biochemistry, 45, 2006
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2C1A
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![BU of 2c1a by Molmil](/molmil-images/mine/2c1a) | Structure of cAMP-dependent protein kinase complexed with Isoquinoline-5-sulfonic acid (2-(2-(4-chlorobenzyloxy)ethylamino) ethyl)amide | 分子名称: | CAMP-DEPENDENT PROTEIN KINASE, CAMP-DEPENDENT PROTEIN KINASE INHIBITOR, ISOQUINOLINE-5-SULFONIC ACID (2-(2-(4-CHLOROBENZYLOXY)ETHYLAMINO)ETHYL)AMIDE | 著者 | Collins, I, Caldwell, J, Fonseca, T, Donald, A, Bavetsias, V, Hunter, L.J, Garrett, M.D, Rowlands, M.G, Aherne, G.W, Davies, T.G, Berdini, V, Woodhead, S.J, Seavers, L.C.A, Wyatt, P.G, Workman, P, McDonald, E. | 登録日 | 2005-09-12 | 公開日 | 2005-11-02 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structure-based design of isoquinoline-5-sulfonamide inhibitors of protein kinase B. Bioorg. Med. Chem., 14, 2006
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2C1B
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![BU of 2c1b by Molmil](/molmil-images/mine/2c1b) | Structure of cAMP-dependent protein kinase complexed with (4R,2S)-5'-(4-(4-Chlorobenzyloxy)pyrrolidin-2-ylmethanesulfonyl)isoquinoline | 分子名称: | (4R,2S)-5'-(4-(4-CHLOROBENZYLOXY)PYRROLIDIN-2-YLMETHANESULFONYL)ISOQUINOLINE, CAMP-DEPENDENT PROTEIN KINASE, CAMP-DEPENDENT PROTEIN KINASE INHIBITOR | 著者 | Collins, I, Caldwell, J, Fonseca, T, Donald, A, Bavetsias, V, Hunter, L.J, Garrett, M.D, Rowlands, M.G, Aherne, G.W, Davies, T.G, Berdini, V, Woodhead, S.J, Seavers, L.C.A, Wyatt, P.G, Workman, P, McDonald, E. | 登録日 | 2005-09-12 | 公開日 | 2005-11-02 | 最終更新日 | 2018-02-28 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure-based design of isoquinoline-5-sulfonamide inhibitors of protein kinase B. Bioorg. Med. Chem., 14, 2006
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2C1C
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![BU of 2c1c by Molmil](/molmil-images/mine/2c1c) | Structural basis of the resistance of an insect carboxypeptidase to plant protease inhibitors | 分子名称: | CARBOXYPEPTIDASE B, YTTRIUM ION, ZINC ION | 著者 | Bayes, A, Comellas-Bigler, M, Rodriguez de la Vega, M, Maskos, K, Bode, W, Aviles, F.X, Jongsma, M.A, Beekwilder, J, Vendrell, J. | 登録日 | 2005-09-12 | 公開日 | 2005-10-19 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural Basis of the Resistance of an Insect Carboxypeptidase to Plant Protease Inhibitors. Proc.Natl.Acad.Sci.USA, 102, 2005
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2C1D
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![BU of 2c1d by Molmil](/molmil-images/mine/2c1d) | Crystal structure of SoxXA from P. pantotrophus | 分子名称: | HEME C, SOXA, SOXX, ... | 著者 | Dambe, T, Quentmeier, A, Rother, D, Friedrich, C, Scheidig, A.J. | 登録日 | 2005-09-13 | 公開日 | 2005-10-06 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Structure of the Cytochrome Complex Soxxa of Paracoccus Pantotrophus, a Heme Enzyme Initiating Chemotrophic Sulfur Oxidation. J.Struct.Biol., 152, 2005
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2C1E
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![BU of 2c1e by Molmil](/molmil-images/mine/2c1e) | Crystal structures of caspase-3 in complex with aza-peptide Michael acceptor inhibitors. | 分子名称: | AZA-PEPTIDE INHIBITOR (5S, 8R, 11S)-8-(2-CARBOXYETHYL)-5-(CARBOXYMETHYL)-14-(4-ETHOXY-4-OXOBUTANOYL)-11-(1-METHYLETHYL)-3,6,9,12-TETRAOXO-1-PHENYL-2-OXA-4,7,10,13,14-PENTAAZAHEXADECAN -16-OIC ACID, ... | 著者 | Grutter, M.G. | 登録日 | 2005-09-14 | 公開日 | 2006-09-20 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Design, Synthesis, and Evaluation of Aza-Peptide Michael Acceptors as Selective and Potent Inhibitors of Caspases-2, -3, -6, -7, -8, -9, and - 10. J.Med.Chem., 49, 2006
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2C1F
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![BU of 2c1f by Molmil](/molmil-images/mine/2c1f) | |