PDB: 5653 件ウェブページステータス検索Chemie searchBIRD

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7DPW	Structural basis for ligand binding modes of CTP synthase 分子名称: CTP synthase, CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION 著者 Liu, J.L, Zhou, X, Guo, C.J, Chang, C.C. 登録日 2020-12-21 公開日 2021-09-15 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (2.65 Å) 主引用文献 Structural basis for ligand binding modes of CTP synthase. Proc.Natl.Acad.Sci.USA, 118, 2021
5AB7	Crystal structure of Trypanosoma brucei SCP2-thiolase like protein (TbSLP) in complex with malonyl-CoA. 分子名称: MALONYL-COENZYME A, SCP2-THIOLASE LIKE PROTEIN, SULFATE ION 著者 Harijan, R.K, Kiema, T.R, Wierenga, R.K. 登録日 2015-08-02 公開日 2016-05-04 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The Scp2-Thiolase-Like Protein (Slp) of Trypanosoma Brucei is an Enzyme Involved in Lipid Metabolism. Proteins, 84, 2016
6VC1	Octreotide oxalate 分子名称: OXALATE ION, Octreotide 著者 Spiliopoulou, M, Karavassili, F, Triandafillidis, D, Valmas, A, Kosinas, C, Fili, S, Barlos, K, Barlos, K.K, Morin, M, Reinle-Schmitt, M, Gozzo, F, Margiolaki, I. 登録日 2019-12-20 公開日 2020-12-23 最終更新日 2021-05-19 実験手法 POWDER DIFFRACTION 主引用文献 New perspectives in macromolecular powder diffraction using single-photon-counting strip detectors: high-resolution structure of the pharmaceutical peptide octreotide. Acta Crystallogr.,Sect.A, 77, 2021
6VL5	BG505 SOSIP reconstructed from a designed tetrahedral nanoparticle, BG505 SOSIP-T33_dn2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP.v5.2(7S) - gp120, ... 著者 Ward, A.B, Antanasijevic, A. 登録日 2020-01-22 公開日 2020-08-12 最終更新日 2020-09-02 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Targeting HIV Env immunogens to B cell follicles in nonhuman primates through immune complex or protein nanoparticle formulations. NPJ Vaccines, 5, 2020
6NE2	Designed repeat protein in complex with Fz7 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... 著者 Miao, Y, Jude, K.M, Garcia, K.C. 登録日 2018-12-15 公開日 2019-05-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.299 Å) 主引用文献 Receptor subtype discrimination using extensive shape complementary designed interfaces. Nat.Struct.Mol.Biol., 26, 2019
6NE4	Designed repeat protein specifically in complex with Fz7CRD 分子名称: 1,2-ETHANEDIOL, Designed repeat binding protein, Frizzled-7, ... 著者 Miao, Y, Jude, K.M, Garcia, K.C. 登録日 2018-12-16 公開日 2019-05-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.648 Å) 主引用文献 Receptor subtype discrimination using extensive shape complementary designed interfaces. Nat.Struct.Mol.Biol., 26, 2019
6NDZ	Designed repeat protein in complex with Fz8 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, ACETIC ACID, ... 著者 Miao, Y, Jude, K.M, Garcia, K.C. 登録日 2018-12-14 公開日 2019-05-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.264 Å) 主引用文献 Receptor subtype discrimination using extensive shape complementary designed interfaces. Nat.Struct.Mol.Biol., 26, 2019
6D02	Cross-alpha Amyloid-like Structure alphaAmL, 2nd form 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CARBONATE ION, PHOSPHATE ION, ... 著者 Zhang, S.-Q, Liu, L, Degrado, W.F. 登録日 2018-04-10 公開日 2019-02-20 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Designed peptides that assemble into cross-alpha amyloid-like structures. Nat. Chem. Biol., 14, 2018
6ZLR	Soaking competent crystal form of the SARS-CoV-2 Receptor Binding Domain (RBD):CR3022 complex. 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CR3022 FAB HEAVY CHAIN, CR3022 FAB LIGHT CHAIN, ... 著者 de Nicola, G.F, Nichols, C.E. 登録日 2020-07-01 公開日 2020-12-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 A New Crystal Form of the SARS-CoV-2 Receptor Binding Domain: CR3022 Complex-An Ideal Target for In-Crystal Fragment Screening of the ACE2 Binding Site Surface. Front Pharmacol, 11, 2020
6WMK	Crystal structure of beta sheet heterodimer LHD29 分子名称: Beta sheet heterodimer LHD29 - Chain A, Beta sheet heterodimer LHD29 - Chain B 著者 Bera, A.K, Sahtoe, D.D, Kang, A, Sankaran, B, Baker, D. 登録日 2020-04-21 公開日 2021-11-10 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Reconfigurable asymmetric protein assemblies through implicit negative design. Science, 375, 2022
6B17	Design of a short thermally stable alpha-helix embedded in a macrocycle 分子名称: 3,3'-dimethyl-1,1'-biphenyl, Capped-strapped peptide 著者 Wu, H, Acharyya, A, Wu, Y, Liu, L, Jo, H, Gai, F, DeGrado, W.F. 登録日 2017-09-17 公開日 2018-02-21 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Design of a Short Thermally Stable alpha-Helix Embedded in a Macrocycle. Chembiochem, 19, 2018
1MM2	Solution structure of the 2nd PHD domain from Mi2b 分子名称: Mi2-beta, ZINC ION 著者 Kwan, A.H.Y, Gell, D.A, Verger, A, Crossley, M, Matthews, J.M, Mackay, J.P. 登録日 2002-09-02 公開日 2003-07-22 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Engineering a Protein Scaffold from a PHD Finger structure, 11, 2003
8VG5	Crystal Structure of V113N Variant of D-Dopachrome Tautomerase (D-DT) Bound with 4CPPC 分子名称: 4-(3-carboxyphenyl)pyridine-2,5-dicarboxylic acid, CITRIC ACID, D-dopachrome decarboxylase 著者 Parkins, A, Pilien, A, Thompson, M.C, Pantouris, G. 登録日 2023-12-22 公開日 2024-05-01 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 The C-terminal Region of D-DT Regulates Molecular Recognition for Protein-Ligand Complexes. J.Med.Chem., 67, 2024
2R5W	Crystal structure of a bifunctional NMN adenylyltransferase/ADP ribose pyrophosphatase from Francisella tularensis 分子名称: CHLORIDE ION, MAGNESIUM ION, Nicotinamide-nucleotide adenylyltransferase 著者 Huang, N, Sorci, L, Zhang, X, Brautigan, C, Li, X, Raffaelli, N, Grishin, N, Osterman, A, Zhang, H. 登録日 2007-09-04 公開日 2008-03-04 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Bifunctional NMN Adenylyltransferase/ADP-Ribose Pyrophosphatase: Structure and Function in Bacterial NAD Metabolism. Structure, 16, 2008
8VFK	Crystal Structure of Delta 109-117 D-Dopachrome Tautomerase (D-DT) 分子名称: CITRATE ANION, D-dopachrome decarboxylase, SODIUM ION 著者 Parkins, A, Pilien, A, Wolff, A, Thompson, M.C, Pantouris, G. 登録日 2023-12-21 公開日 2024-05-01 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 The C-terminal Region of D-DT Regulates Molecular Recognition for Protein-Ligand Complexes. J.Med.Chem., 67, 2024
8VDY	Crystal Structure of Delta 114-117 D-Dopachrome Tautomerase (D-DT) 分子名称: D-dopachrome decarboxylase 著者 Parkins, A, Pilien, A, Wolff, A, Thompson, M.C, Pantouris, G. 登録日 2023-12-18 公開日 2024-05-01 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.44 Å) 主引用文献 The C-terminal Region of D-DT Regulates Molecular Recognition for Protein-Ligand Complexes. J.Med.Chem., 67, 2024
2RBL	High resolution design of a protein loop 分子名称: Tenascin 著者 Hu, X, Wang, H, Ke, H, Kuhlman, B. 登録日 2007-09-19 公開日 2007-11-20 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 High-resolution design of a protein loop. Proc.Natl.Acad.Sci.Usa, 104, 2007
8VG8	Crystal Structure of T115A Variant of D-Dopachrome Tautomerase (D-DT) Bound to 4CPPC 分子名称: 4-(3-carboxyphenyl)pyridine-2,5-dicarboxylic acid, D-dopachrome decarboxylase 著者 Parkins, A, Pilien, A, Wolff, A, Thompson, M.C, Pantouris, G. 登録日 2023-12-23 公開日 2024-05-01 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.33 Å) 主引用文献 The C-terminal Region of D-DT Regulates Molecular Recognition for Protein-Ligand Complexes. J.Med.Chem., 67, 2024
8VFO	Crystal Structure of L117G Variant of D-Dopachrome Tautomerase (D-DT) 分子名称: CITRIC ACID, D-dopachrome decarboxylase 著者 Parkins, A, Pilien, A, Thompson, M.C, Pantouris, G. 登録日 2023-12-21 公開日 2024-05-01 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 The C-terminal Region of D-DT Regulates Molecular Recognition for Protein-Ligand Complexes. J.Med.Chem., 67, 2024
8VFL	Crystal Structure of WT D-Dopachrome Tautomerase (D-DT) at 290K 分子名称: D-dopachrome decarboxylase 著者 Parkins, A, Pilien, A, Wolff, A, Thompson, M.C, Pantouris, G. 登録日 2023-12-21 公開日 2024-05-01 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.23 Å) 主引用文献 The C-terminal Region of D-DT Regulates Molecular Recognition for Protein-Ligand Complexes. J.Med.Chem., 67, 2024
8VG7	Crystal Structure of T115A Variant of D-Dopachrome Tautomerase (D-DT) 分子名称: D-dopachrome decarboxylase 著者 Parkins, A, Pilien, A, Wolff, A, Thompson, M.C, Pantouris, G. 登録日 2023-12-23 公開日 2024-05-01 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.24 Å) 主引用文献 The C-terminal Region of D-DT Regulates Molecular Recognition for Protein-Ligand Complexes. J.Med.Chem., 67, 2024
8VFN	Crystal Structure of WT D-Dopachrome Tautomerase (D-DT) at 310K 分子名称: D-dopachrome decarboxylase 著者 Parkins, A, Pilien, A, Wolff, A, Thompson, M.C, Pantouris, G. 登録日 2023-12-21 公開日 2024-05-01 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.29 Å) 主引用文献 The C-terminal Region of D-DT Regulates Molecular Recognition for Protein-Ligand Complexes. J.Med.Chem., 67, 2024
8VFW	Crystal Structure of V113N D-Dopachrome Tautomerase (D-DT) 分子名称: CITRIC ACID, D-dopachrome decarboxylase 著者 Parkins, A, Wolff, A, Thompson, M.C, Pantouris, G. 登録日 2023-12-22 公開日 2024-05-01 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.31 Å) 主引用文献 The C-terminal Region of D-DT Regulates Molecular Recognition for Protein-Ligand Complexes. J.Med.Chem., 67, 2024
3VBX	Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design 分子名称: 6-bromo-4-hydroxy-2H-chromen-2-one, Serine/threonine-protein kinase pim-1 著者 Liu, J. 登録日 2012-01-02 公開日 2012-03-21 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Implications of promiscuous Pim-1 kinase fragment inhibitor hydrophobic interactions for fragment-based drug design. J.Med.Chem., 55, 2012
4UP1	Crystal structure of native human Thymidylate synthase in active form 分子名称: SULFATE ION, THYMIDYLATE SYNTHASE 著者 Deschamps, P, Rety, S, Leulliot, N. 登録日 2014-06-11 公開日 2015-06-24 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.991 Å) 主引用文献 Crystal structure of the active form of native human thymidylate synthase in the absence of bound substrates. Acta Crystallogr F Struct Biol Commun, 73, 2017

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