PDB: 46006 件ウェブページステータス検索Chemie searchBIRD

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5FMZ	Crystal structure of Influenza B polymerase with bound 5' vRNA 分子名称: 5'-R(*AP*GP*UP*AP*GP*UP*AP*AP*CP*AP*AP*GP)-3', POLYMERASE ACIDIC PROTEIN, POLYMERASE BASIC PROTEIN 2, ... 著者 Guilligay, D, Cusack, S. 登録日 2015-11-10 公開日 2016-01-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Influenza Polymerase Can Adopt an Alternative Configuration Involving a Radical Repacking of Pb2 Domains. Mol.Cell, 61, 2016
8F5Z	Composite map of CryoEM structure of Arabidopsis thaliana phytochrome A 分子名称: 3-[5-[[(3~{R},4~{R})-3-ethyl-4-methyl-5-oxidanylidene-3,4-dihydropyrrol-2-yl]methyl]-2-[[5-[(4-ethyl-3-methyl-5-oxidanylidene-pyrrol-2-yl)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1~{H}-pyrrol-2-yl]methyl]-4-methyl-1~{H}-pyrrol-3-yl]propanoic acid, Phytochrome A 著者 Li, H, Li, H. 登録日 2022-11-15 公開日 2023-06-28 最終更新日 2023-08-02 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 The structure of Arabidopsis phytochrome A reveals topological and functional diversification among the plant photoreceptor isoforms. Nat.Plants, 9, 2023
5X7D	Structure of beta2 adrenoceptor bound to carazolol and an intracellular allosteric antagonist 分子名称: (2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol, 1,4-BUTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Liu, X, Ahn, S, Kahsai, A.W, Meng, K.-C, Latorraca, N.R, Pani, B, Venkatakrishnan, A.J, Masoudi, A, Weis, W.I, Dror, R.O, Chen, X, Lefkowitz, R.J, Kobilka, B.K. 登録日 2017-02-25 公開日 2017-08-16 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.703 Å) 主引用文献 Mechanism of intracellular allosteric beta 2AR antagonist revealed by X-ray crystal structure. Nature, 548, 2017
8KDC	Cryo-EM structure of the human parainfluenza virus hPIV3 L-P polymerase in monomeric form 分子名称: MAGNESIUM ION, Phosphoprotein, RNA-directed RNA polymerase L, ... 著者 Xie, J, Wang, L, Zhai, G, Wu, D, Lin, Z, Wang, M, Yan, X, Gao, L, Huang, X, Fearns, R, Chen, S. 登録日 2023-08-09 公開日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structural basis for dimerization of a paramyxovirus polymerase complex. Nat Commun, 15, 2024
8KDB	Cryo-EM structure of the human parainfluenza virus hPIV3 L-P polymerase in dimeric form 分子名称: MAGNESIUM ION, Phosphoprotein, RNA-directed RNA polymerase L, ... 著者 Xie, J, Wang, L, Zhai, G, Wu, D, Lin, Z, Wang, M, Yan, X, Gao, L, Huang, X, Fearns, R, Chen, S. 登録日 2023-08-09 公開日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Structural basis for dimerization of a paramyxovirus polymerase complex. Nat Commun, 15, 2024
8QC0	Nucleoside 2'deoxyribosyltransferase from Chroococcidiopsis thermalis PCC 7203 WT ribosylated 分子名称: Nucleoside 2-deoxyribosyltransferase, ZINC ION, alpha-D-ribofuranose 著者 Tang, P, Harding, C.J, Czekster, C.M. 登録日 2023-08-25 公開日 2024-02-21 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Snapshots of the Reaction Coordinate of a Thermophilic 2'-Deoxyribonucleoside/ribonucleoside Transferase. Acs Catalysis, 14, 2024
7NHX	1918 H1N1 Viral influenza polymerase heterotrimer - full transcriptase (Class1) 分子名称: Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ... 著者 Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. 登録日 2021-02-11 公開日 2021-12-01 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.23 Å) 主引用文献 Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
7NIS	1918 H1N1 Viral influenza polymerase heterotrimer with Nb8192 core 分子名称: Nanobody8192 core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ... 著者 Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. 登録日 2021-02-13 公開日 2021-12-01 最終更新日 2022-02-09 実験手法 ELECTRON MICROSCOPY (5.96 Å) 主引用文献 Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
7NK6	1918 H1N1 Viral influenza polymerase heterotrimer with Nb8204 分子名称: Nb8204, Polymerase acidic protein, Polymerase basic protein 2,Polymerase basic protein 2, ... 著者 Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. 登録日 2021-02-17 公開日 2021-12-01 最終更新日 2022-02-09 実験手法 ELECTRON MICROSCOPY (6.72 Å) 主引用文献 Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
7NK1	1918 Influenza virus polymerase heterotirmer in complex with vRNA promoters and Nb8201 分子名称: Nanobody8201, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ... 著者 Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. 登録日 2021-02-17 公開日 2021-12-01 最終更新日 2022-02-09 実験手法 ELECTRON MICROSCOPY (4.22 Å) 主引用文献 Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
7NJ7	1918 H1N1 Viral influenza polymerase heterotrimer with Nb8200 core 分子名称: Nb8200 core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ... 著者 Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. 登録日 2021-02-16 公開日 2021-12-01 最終更新日 2022-02-09 実験手法 ELECTRON MICROSCOPY (4.82 Å) 主引用文献 Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
7NKA	1918 H1N1 Viral influenza polymerase heterotrimer with Nb8206 分子名称: NB8206, Polymerase acidic protein, Polymerase basic protein 2,Polymerase basic protein 2, ... 著者 Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. 登録日 2021-02-17 公開日 2021-12-01 最終更新日 2022-02-09 実験手法 ELECTRON MICROSCOPY (4.07 Å) 主引用文献 Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
7NKI	1918 H1N1 Viral influenza polymerase heterotrimer with Nb8209 core 分子名称: Nb8209, Polymerase acidic protein, Polymerase basic protein 2,Polymerase basic protein 2, ... 著者 Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. 登録日 2021-02-18 公開日 2021-12-01 最終更新日 2022-02-09 実験手法 ELECTRON MICROSCOPY (4.67 Å) 主引用文献 Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
7NKR	1918 H1N1 Viral influenza polymerase heterotrimer with Nb8210 分子名称: Nb8210, Polymerase acidic protein, Polymerase basic protein 2,Polymerase basic protein 2, ... 著者 Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. 登録日 2021-02-18 公開日 2021-12-01 最終更新日 2022-02-09 実験手法 ELECTRON MICROSCOPY (5.6 Å) 主引用文献 Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
7NI0	1918 H1N1 Viral influenza polymerase heterotrimer - Replicase (class 3) 分子名称: Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ... 著者 Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. 登録日 2021-02-11 公開日 2021-12-01 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.32 Å) 主引用文献 Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
7NIR	1918 H1N1 Viral influenza polymerase heterotrimer with Nb8191 core 分子名称: Nanobody8191 core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ... 著者 Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. 登録日 2021-02-13 公開日 2021-12-01 最終更新日 2022-02-09 実験手法 ELECTRON MICROSCOPY (6.7 Å) 主引用文献 Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
7NK2	1918 H1N1 Viral influenza polymerase heterotrimer with Nb8202 core 分子名称: Nanobody8202, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ... 著者 Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. 登録日 2021-02-17 公開日 2021-12-01 最終更新日 2022-02-09 実験手法 ELECTRON MICROSCOPY (4.84 Å) 主引用文献 Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
7NHA	1918 H1N1 Viral influenza polymerase heterotrimer - Endonuclease and priming loop ordered (Class2a) 分子名称: Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ... 著者 Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. 登録日 2021-02-10 公開日 2021-12-01 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (2.91 Å) 主引用文献 Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
7NJ4	1918 H1N1 Viral influenza polymerase heterotrimer with Nb8198 core 分子名称: Nb8198 Core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ... 著者 Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. 登録日 2021-02-16 公開日 2021-12-01 最終更新日 2022-02-09 実験手法 ELECTRON MICROSCOPY (5.84 Å) 主引用文献 Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
7NK4	1918 H1N1 Viral influenza polymerase heterotrimer with Nb8203 core 分子名称: Nanobody 8203, Polymerase acidic protein, Polymerase basic protein 2,Polymerase basic protein 2, ... 著者 Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. 登録日 2021-02-17 公開日 2021-12-01 最終更新日 2022-02-09 実験手法 ELECTRON MICROSCOPY (5.32 Å) 主引用文献 Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
7NIK	1918 H1N1 Viral influenza polymerase heterotrimer with Nb8189 core 分子名称: Nanobody8189 core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ... 著者 Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. 登録日 2021-02-12 公開日 2021-12-01 最終更新日 2022-02-09 実験手法 ELECTRON MICROSCOPY (6.2 Å) 主引用文献 Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
7NJ3	1918 H1N1 Viral influenza polymerase heterotrimer with Nb8196 core 分子名称: Nanobody8196 core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ... 著者 Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. 登録日 2021-02-15 公開日 2021-12-01 最終更新日 2022-02-09 実験手法 ELECTRON MICROSCOPY (4.48 Å) 主引用文献 Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
7NJ5	1918 H1N1 Viral influenza polymerase heterotrimer with Nb8199 core 分子名称: Nb8199 Core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ... 著者 Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. 登録日 2021-02-16 公開日 2021-12-01 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (4.63 Å) 主引用文献 Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
7NK8	1918 H1N1 Viral influenza polymerase heterotrimer with Nb8205 core 分子名称: Nb8205, Polymerase acidic protein, Polymerase basic protein 2,Polymerase basic protein 2, ... 著者 Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. 登録日 2021-02-17 公開日 2021-12-01 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (5.34 Å) 主引用文献 Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun, 13, 2022
6V8B	Crystal structure of the p300 acetyltransferase domain with AcCoA competitive inhibitor 1 分子名称: 4-(2-{[(1R)-2-(1H-indol-3-yl)-2-oxo-1-phenylethyl]amino}ethyl)benzene-1-sulfonamide, CHLORIDE ION, Histone acetyltransferase p300, ... 著者 Gardberg, A.S. 登録日 2019-12-10 公開日 2020-04-01 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3.13 Å) 主引用文献 Early Drug-Discovery Efforts towards the Identification of EP300/CBP Histone Acetyltransferase (HAT) Inhibitors. Chemmedchem, 15, 2020

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