8TWD
 
 | | Structure of IraM-bound RssB | | 分子名称: | ACETATE ION, Anti-adapter protein IraM, Regulator of RpoS | | 著者 | Brugger, C, Deaconescu, A.M. | | 登録日 | 2023-08-20 | | 公開日 | 2024-01-10 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | IraM remodels the RssB segmented helical linker to stabilize sigma s against degradation by ClpXP.
J.Biol.Chem., 300, 2023
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8TWC
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8TW3
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8TW2
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8TW1
 | | Crystal structure of Lys2972, a phage endolysin targeting Streptococcus thermophilus | | 分子名称: | Endolysin Lys2972, GLYCEROL, SODIUM ION | | 著者 | Zhu, X, Moineau, S, Shi, R. | | 登録日 | 2023-08-18 | | 公開日 | 2024-03-27 | | 最終更新日 | 2024-04-10 | | 実験手法 | X-RAY DIFFRACTION (1.27 Å) | | 主引用文献 | Fermentation Practices Select for Thermostable Endolysins in Phages.
Mol.Biol.Evol., 41, 2024
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8TW0
 | | Crystal Structure of a synthetic ABC heterotrimeric Collagen-like Peptide at 1.53 A | | 分子名称: | Collagen Mimetic Peptide A, Collagen Mimetic Peptide B, Collagen Mimetic Peptide C, ... | | 著者 | Miller, M.D, Cole, C.C, Xu, W, Walker, D.R, Hulgan, S.A.H, Pogostin, B.H, Swain, J.W.R, Duella, R, Misiura, M, Wang, X, Kolomeisky, A.B, Phillips Jr, G.N, Hartgerink, J.D. | | 登録日 | 2023-08-18 | | 公開日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | Heterotrimeric Collagen Helix with High Specificity of Assembly Results in a Rapid Rate of Folding
Nat.Chem., 2024
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8TVZ
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8TVY
 | | Cryo-EM structure of CPD lesion containing RNA Polymerase II elongation complex with Rad26 and Elf1 (closed state) | | 分子名称: | DNA (NTS), DNA (TS), DNA-directed RNA polymerase II subunit RPB1, ... | | 著者 | Sarsam, R.D, Lahiri, I, Leschziner, A.E. | | 登録日 | 2023-08-18 | | 公開日 | 2024-01-24 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8TVX
 | | Cryo-EM structure of CPD-stalled Pol II (Conformation 2) | | 分子名称: | DNA (NTS), DNA (TS), DNA-directed RNA polymerase II subunit RPB1, ... | | 著者 | Sarsam, R.D, Lahiri, I, Leschziner, A.E. | | 登録日 | 2023-08-18 | | 公開日 | 2024-01-24 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8TVW
 | | Cryo-EM structure of CPD-stalled Pol II (conformation 1) | | 分子名称: | DNA (NTS), DNA (TS), DNA-directed RNA polymerase II subunit RPB1, ... | | 著者 | Sarsam, R.D, Lahiri, I, Leschziner, A.E. | | 登録日 | 2023-08-18 | | 公開日 | 2024-01-24 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8TVV
 | | Cryo-EM structure of backtracked Pol II | | 分子名称: | DNA (NTS), DNA (TS), DNA-directed RNA polymerase II subunit RPB1, ... | | 著者 | Sarsam, R.D, Lahiri, I, Leschziner, A.E. | | 登録日 | 2023-08-18 | | 公開日 | 2024-01-24 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8TVU
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8TVS
 | | Cryo-EM structure of backtracked Pol II in complex with Rad26 | | 分子名称: | DNA (NTS), DNA (TS), DNA repair and recombination protein RAD26, ... | | 著者 | Sarsam, R.D, Lahiri, I, Leschziner, A.E. | | 登録日 | 2023-08-18 | | 公開日 | 2024-01-24 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8TVR
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8TVQ
 | | Cryo-EM structure of CPD stalled 10-subunit Pol II in complex with Rad26 | | 分子名称: | DNA (NTS), DNA (TS), DNA repair and recombination protein RAD26, ... | | 著者 | Sarsam, R.D, Lahiri, I, Leschziner, A.E. | | 登録日 | 2023-08-18 | | 公開日 | 2024-01-24 | | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | | 主引用文献 | Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8TVP
 | | Cryo-EM structure of CPD-stalled Pol II in complex with Rad26 (open state) | | 分子名称: | DNA (NTS), DNA (TS), DNA repair and recombination protein RAD26, ... | | 著者 | Sarsam, R.D, Lahiri, I, Leschziner, A.E. | | 登録日 | 2023-08-18 | | 公開日 | 2024-01-24 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8TVN
 | | IRAK4 in complex with compound 23 | | 分子名称: | Interleukin-1 receptor-associated kinase 4, N-{1-[(1R,2S)-2-fluorocyclopropyl]-2-oxo-1,2-dihydropyridin-3-yl}-2-[(1R,4r)-1-methyl-2-oxabicyclo[2.1.1]hexan-4-yl]-6-[(propan-2-yl)oxy]-2H-pyrazolo[3,4-b]pyridine-5-carboxamide | | 著者 | Metrick, C.M, Chodaparambil, J.V. | | 登録日 | 2023-08-18 | | 公開日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | A Tiny Pocket Packs a Punch: Leveraging Pyridones for the Discovery of CNS-Penetrant Aza-indazole IRAK4 Inhibitors.
Acs Med.Chem.Lett., 15, 2024
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8TVM
 | | IRAK4 in complex with compound 24 | | 分子名称: | Interleukin-1 receptor-associated kinase 4, N-{1-[(1R,2R)-2-fluorocyclopropyl]-2-oxo-1,2-dihydropyridin-3-yl}-2-[(1R,4r)-1-methyl-2-oxabicyclo[2.1.1]hexan-4-yl]-6-[(propan-2-yl)oxy]-2H-pyrazolo[3,4-b]pyridine-5-carboxamide | | 著者 | Metrick, C.M, Chodaparambil, J.V. | | 登録日 | 2023-08-18 | | 公開日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | A Tiny Pocket Packs a Punch: Leveraging Pyridones for the Discovery of CNS-Penetrant Aza-indazole IRAK4 Inhibitors.
Acs Med.Chem.Lett., 15, 2024
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8TVL
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8TVI
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8TVH
 | | Langya henipavirus postfusion F protein in complex with 4G5 Fab, local refinement of the viral membrane proximal region | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4G5 heavy chain, 4G5 light chain, ... | | 著者 | Wang, Z, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D. | | 登録日 | 2023-08-18 | | 公開日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structure and design of Langya virus glycoprotein antigens.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8TVG
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8TVF
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8TVE
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8TVB
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