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6D6R
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BU of 6d6r by Molmil
Human nuclear exosome-MTR4 RNA complex - composite map after focused reconstruction
分子名称: DNA/RNA (62-MER), Exosome RNA helicase MTR4, Exosome complex component CSL4, ...
著者Weick, E.-M, Lima, C.D.
登録日2018-04-22
公開日2018-06-20
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.45 Å)
主引用文献Helicase-Dependent RNA Decay Illuminated by a Cryo-EM Structure of a Human Nuclear RNA Exosome-MTR4 Complex.
Cell, 173, 2018
6D6Q
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BU of 6d6q by Molmil
Human nuclear exosome-MTR4 RNA complex - overall reconstruction
分子名称: DNA/RNA (62-MER), Exosome RNA helicase MTR4, Exosome complex component CSL4, ...
著者Weick, E.-M, Lima, C.D.
登録日2018-04-22
公開日2018-06-20
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.45 Å)
主引用文献Helicase-Dependent RNA Decay Illuminated by a Cryo-EM Structure of a Human Nuclear RNA Exosome-MTR4 Complex.
Cell, 173, 2018
6DFA
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BU of 6dfa by Molmil
Kaiso (ZBTB33) E535A zinc finger DNA binding domain in complex with the specific Kaiso binding sequence (KBS)
分子名称: CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*GP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), ...
著者Nikolova, E.N, Stanfield, R.L, Dyson, H.J, Wright, P.E.
登録日2018-05-14
公開日2019-05-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.908 Å)
主引用文献A conformational switch in the zinc finger protein Kaiso mediates differential readout of specific and methylated DNA sequences.
Biochemistry, 2020
6LTJ
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BU of 6ltj by Molmil
Structure of nucleosome-bound human BAF complex
分子名称: AT-rich interactive domain-containing protein 1A, Actin, cytoplasmic 1, ...
著者He, S, Wu, Z, Tian, Y, Yu, Z, Yu, J, Wang, X, Li, J, Liu, B, Xu, Y.
登録日2020-01-22
公開日2020-02-12
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structure of nucleosome-bound human BAF complex.
Science, 367, 2020
6LSS
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BU of 6lss by Molmil
Cryo-EM structure of a pre-60S ribosomal subunit - state preA
分子名称: 28S rRNA, 5S rRNA, 60S ribosomal protein L11, ...
著者Liang, X, Zuo, M, Zhang, Y, Li, N, Ma, C, Dong, M, Gao, N.
登録日2020-01-20
公開日2020-08-26
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献Structural snapshots of human pre-60S ribosomal particles before and after nuclear export.
Nat Commun, 11, 2020
6LTH
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BU of 6lth by Molmil
Structure of human BAF Base module
分子名称: AT-rich interactive domain-containing protein 1A, SWI/SNF complex subunit SMARCC2, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1, ...
著者He, S, Wu, Z, Tian, Y, Yu, Z, Yu, J, Wang, X, Li, J, Liu, B, Xu, Y.
登録日2020-01-22
公開日2020-02-12
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structure of nucleosome-bound human BAF complex.
Science, 367, 2020
6LU8
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BU of 6lu8 by Molmil
Cryo-EM structure of a human pre-60S ribosomal subunit - state A
分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Liang, X, Zuo, M, Zhang, Y, Li, N, Ma, C, Dong, M, Gao, N.
登録日2020-01-26
公開日2020-08-26
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献Structural snapshots of human pre-60S ribosomal particles before and after nuclear export.
Nat Commun, 11, 2020
8X15
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BU of 8x15 by Molmil
Structure of nucleosome-bound SRCAP-C in the apo state
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
著者Yu, J, Wang, Q, Yu, Z, Li, W, Wang, L, Xu, Y.
登録日2023-11-06
公開日2024-03-06
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural insights into histone exchange by human SRCAP complex.
Cell Discov, 10, 2024
8X19
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BU of 8x19 by Molmil
Structure of nucleosome-bound SRCAP-C in the ADP-BeFx-bound state
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
著者Yu, J, Wang, Q, Yu, Z, Li, W, Wang, L, Xu, Y.
登録日2023-11-06
公開日2024-03-06
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural insights into histone exchange by human SRCAP complex.
Cell Discov, 10, 2024
2LLH
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BU of 2llh by Molmil
NMR structure of Npm1_c70
分子名称: Nucleophosmin
著者Banci, L, Bertini, I, Brunori, M, Di Matteo, A, Federici, L, Gallo, A, Lo Sterzo, C, Mori, M.
登録日2011-11-09
公開日2012-06-27
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure of Nucleophosmin DNA-binding Domain and Analysis of Its Complex with a G-quadruplex Sequence from the c-MYC Promoter.
J.Biol.Chem., 287, 2012
3EX7
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BU of 3ex7 by Molmil
The crystal structure of EJC in its transition state
分子名称: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Eukaryotic initiation factor 4A-III, ...
著者Andersen, G.R, Nielsen, K.H.
登録日2008-10-16
公開日2008-12-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Mechanism of ATP turnover inhibition in the EJC
Rna, 15, 2009
3IYG
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BU of 3iyg by Molmil
Ca model of bovine TRiC/CCT derived from a 4.0 Angstrom cryo-EM map
分子名称: T-complex protein 1 subunit, T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, ...
著者Cong, Y, Baker, M.L, Ludtke, S.J, Frydman, J, Chiu, W.
登録日2009-11-28
公開日2010-03-16
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献4.0-A resolution cryo-EM structure of the mammalian chaperonin TRiC/CCT reveals its unique subunit arrangement.
Proc.Natl.Acad.Sci.USA, 107, 2010
2MXY
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BU of 2mxy by Molmil
Solution structure of hnRNP C RRM in complex with 5'-AUUUUUC-3' RNA
分子名称: 5'-R(*AP*UP*UP*UP*UP*UP*C)-3', Heterogeneous nuclear ribonucleoproteins C1/C2
著者Cienikova, Z, Damberger, F.F, Hall, J, Allain, F.H.-T, Maris, C.
登録日2015-01-19
公開日2015-02-25
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural and mechanistic insights into poly(uridine) tract recognition by the hnRNP C RNA recognition motif.
J.Am.Chem.Soc., 136, 2014
2MZ1
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BU of 2mz1 by Molmil
Solution structure of hnRNP C RRM in complex with 5'-UUUUC-3' RNA
分子名称: 5'-R(*UP*UP*UP*UP*C)-3', Heterogeneous nuclear ribonucleoproteins C1/C2
著者Cienikova, Z, Damberger, F.F, Hall, J, Allain, F.H.-T, Maris, C.
登録日2015-02-05
公開日2015-04-08
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural and mechanistic insights into poly(uridine) tract recognition by the hnRNP C RNA recognition motif.
J.Am.Chem.Soc., 136, 2014
5HO4
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BU of 5ho4 by Molmil
Crystal structure of hnRNPA2B1 in complex with 10-mer RNA
分子名称: Heterogeneous nuclear ribonucleoproteins A2/B1, RNA (5'-R(*AP*AP*GP*GP*AP*CP*UP*AP*GP*C)-3')
著者Wu, B.X, Su, S.C, Gan, J.H, Ma, J.B.
登録日2016-01-19
公開日2017-02-08
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1.
Nat Commun, 9, 2018
4WIJ
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BU of 4wij by Molmil
HUMAN SPLICING FACTOR, CONSTRUCT 1
分子名称: Splicing factor, proline- and glutamine-rich
著者lee, M, bond, c.s.
登録日2014-09-26
公開日2015-04-01
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.49 Å)
主引用文献The structure of human SFPQ reveals a coiled-coil mediated polymer essential for functional aggregation in gene regulation.
Nucleic Acids Res., 43, 2015
4WJ8
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BU of 4wj8 by Molmil
Human Pyruvate Kinase M2 Mutant C424A
分子名称: 1,6-di-O-phosphono-beta-D-fructofuranose, GLYCEROL, MAGNESIUM ION, ...
著者Mitchell, T, Yuan, M, McNae, I, Morgan, H, Walkinshaw, M.D.
登録日2014-09-29
公開日2015-09-30
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.87 Å)
主引用文献Human Pyruvate Kinase M2 Mutant C424A
To Be Published
4WII
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BU of 4wii by Molmil
HUMAN SPLICING FACTOR, CONSTRUCT 3
分子名称: 1,2-ETHANEDIOL, SULFATE ION, Splicing factor, ...
著者lee, M, bond, c.s.
登録日2014-09-26
公開日2015-04-01
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献The structure of human SFPQ reveals a coiled-coil mediated polymer essential for functional aggregation in gene regulation.
Nucleic Acids Res., 43, 2015
2PX9
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BU of 2px9 by Molmil
The intrinsic affinity between E2 and the Cys domain of E1 in Ubiquitin-like modifications
分子名称: SUMO-activating enzyme subunit 2, SUMO-conjugating enzyme UBC9
著者Wang, J.H, Hu, W.D, Cai, S, Lee, B, Song, J, Chen, Y.
登録日2007-05-14
公開日2007-07-24
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The intrinsic affinity between E2 and the Cys domain of E1 in ubiquitin-like modifications.
Mol.Cell, 27, 2007
2RO1
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BU of 2ro1 by Molmil
NMR Solution Structures of Human KAP1 PHD finger-bromodomain
分子名称: Transcription intermediary factor 1-beta, ZINC ION
著者Zeng, L, Yap, K.L, Ivanov, A.V, Wang, X, Mujtaba, S, Plotnikova, O, Rauscher, F.J.
登録日2008-03-04
公開日2008-05-20
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structural insights into human KAP1 PHD finger-bromodomain and its role in gene silencing
Nat.Struct.Mol.Biol., 15, 2008
2O25
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BU of 2o25 by Molmil
Ubiquitin-Conjugating Enzyme E2-25 kDa Complexed With SUMO-1-Conjugating Enzyme UBC9
分子名称: SUMO-1-conjugating enzyme UBC9, Ubiquitin-conjugating enzyme E2-25 kDa
著者Walker, J.R, Avvakumov, G.V, Xue, S, Newman, E.M, Mackenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2006-11-29
公開日2007-01-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A Novel and Unexpected Complex Between the SUMO-1-Conjugating Enzyme UBC9 and the Ubiquitin-Conjugating Enzyme E2-25 kDa
To be Published
2UYY
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BU of 2uyy by Molmil
Structure of the cytokine-like nuclear factor n-pac
分子名称: N-PAC PROTEIN, POTASSIUM ION, [(2R,3R,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3-HYDROXY-4-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL [(2R,3S,4S)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE
著者Tickle, J, Pilka, E.S, Bunkoczi, G, Berridge, G, Smee, C, Kavanagh, K.L, Hozjan, V, Niesen, F.H, Papagrigoriou, E, Pike, A.C.W, Turnbull, A, Arrowsmith, C.H, Edwards, A, Sundstrom, M, Weigelt, J, von Delft, F, Oppermann, U.
登録日2007-04-20
公開日2007-07-03
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The Structure of the Cytokine-Like Nuclear Factor N-Pac
To be Published
1U1Q
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BU of 1u1q by Molmil
Crystal Structure of UP1 Complexed With d(TTAGGGTTA(DI)GG); A Human Telomeric Repeat Containing Inosine
分子名称: 5'-D(*TP*AP*GP*GP*GP*TP*TP*AP*(OIP)*GP*G)-3', Heterogeneous nuclear ribonucleoprotein A1
著者Myers, J.C, Shamoo, Y.
登録日2004-07-15
公開日2004-09-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Human UP1 as a Model for Understanding Purine Recognition in the Family of Proteins Containing the RNA Recognition Motif (RRM).
J.Mol.Biol., 342, 2004
1U1P
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BU of 1u1p by Molmil
Crystal Structure of UP1 Complexed With d(TTAGGGTTA 2PR GG); A Human Telomeric Repeat Containing 2-aminopurine
分子名称: 5'-D(*T*TP*AP*GP*GP*GP*TP*TP*AP*(2PR)P*GP*G)-3', Heterogeneous nuclear ribonucleoprotein A1
著者Myers, J.C, Shamoo, Y.
登録日2004-07-15
公開日2004-09-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Human UP1 as a Model for Understanding Purine Recognition in the Family of Proteins Containing the RNA Recognition Motif (RRM).
J.Mol.Biol., 342, 2004
1U1L
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Crystal Structure of UP1 Complexed With d(TTAGGGTT PRN GGG); A Human Telomeric Repeat Containing nebularine
分子名称: 5'-D(*TP*AP*GP*GP*GP*TP*TP*(PRN)P*GP*GP*G)-3', Heterogeneous nuclear ribonucleoprotein A1
著者Myers, J.C, Shamoo, Y.
登録日2004-07-15
公開日2004-09-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Human UP1 as a Model for Understanding Purine Recognition in the Family of Proteins Containing the RNA Recognition Motif (RRM).
J.Mol.Biol., 342, 2004

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