6NIX
 
 | | Crystal structure of Immune Receptor | | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, ... | | 著者 | Ting, Y.T, Reid, H.H, Rossjohn, J. | | 登録日 | 2019-01-01 | | 公開日 | 2020-01-22 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Immune Receptor
To Be Published
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2ICW
 | | Crystal structure of a complete ternary complex between TCR, superantigen, and peptide-MHC class II molecule | | 分子名称: | HLA class II histocompatibility antigen, DR alpha chain, DRB1-1 beta chain, ... | | 著者 | Wang, L, Zhao, Y, Li, H. | | 登録日 | 2006-09-13 | | 公開日 | 2007-03-20 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | | 主引用文献 | Crystal structure of a complete ternary complex of TCR, superantigen and peptide-MHC.
Nat.Struct.Mol.Biol., 14, 2007
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4GBX
 | | Crystal structure of an immune complex at pH 6.5 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DM alpha chain, ... | | 著者 | Sethi, D.K, Pos, W, Wucherpfennig, K.W. | | 登録日 | 2012-07-28 | | 公開日 | 2013-01-16 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal Structure of the HLA-DM-HLA-DR1 Complex Defines Mechanisms for Rapid Peptide Selection.
Cell(Cambridge,Mass.), 151, 2012
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2IPK
 | | Crystal Structure of the MHC Class II Molecule HLA-DR1 in Complex with the Fluorogenic Peptide, AcPKXVKQNTLKLAT (X=3-[5-(dimethylamino)-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl]-L-alanine) and the Superantigen, SEC3 Variant 3B2 | | 分子名称: | Enterotoxin type C-3, HA related Fluorogenic Peptide, AcPKXVKQNTLKLAT (X=3-[5-(dimethylamino)-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl]-L-alanine), ... | | 著者 | Nguyen, T.T, Stern, L.J. | | 登録日 | 2006-10-12 | | 公開日 | 2007-03-13 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Fluorogenic probes for monitoring peptide binding to class II MHC proteins in living cells.
Nat.Chem.Biol., 3, 2007
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6V13
 | | immune receptor complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fibrinogen beta 74cit69-81, G08 TCR alpha chain, ... | | 著者 | Lim, J.J, Rossjohn, J. | | 登録日 | 2019-11-19 | | 公開日 | 2020-11-25 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | The shared susceptibility epitope of HLA-DR4 binds citrullinated self-antigens and the TCR.
Sci Immunol, 6, 2021
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6V1A
 | | immune receptor complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fibrinogen beta 74cit69-81, GLYCEROL, ... | | 著者 | Lim, J.J, Rossjohn, J. | | 登録日 | 2019-11-20 | | 公開日 | 2020-11-25 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | The shared susceptibility epitope of HLA-DR4 binds citrullinated self-antigens and the TCR.
Sci Immunol, 6, 2021
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6V15
 | | immune receptor complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fibrinogen beta 72,74cit69-81, G08 TCR alpha chain, ... | | 著者 | Lim, J.J, Rossjohn, J. | | 登録日 | 2019-11-19 | | 公開日 | 2020-11-25 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | The shared susceptibility epitope of HLA-DR4 binds citrullinated self-antigens and the TCR.
Sci Immunol, 6, 2021
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6V0Y
 | | immune receptor complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fibrinogen beta 72,74cit69-81, GLYCEROL, ... | | 著者 | Lim, J.J, Rossjohn, J. | | 登録日 | 2019-11-19 | | 公開日 | 2020-11-25 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | The shared susceptibility epitope of HLA-DR4 binds citrullinated self-antigens and the TCR.
Sci Immunol, 6, 2021
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6V19
 | | immune receptor complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fibrinogen beta 72,74cit69-81, GLYCEROL, ... | | 著者 | Lim, J.J, Rossjohn, J. | | 登録日 | 2019-11-20 | | 公開日 | 2020-11-25 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The shared susceptibility epitope of HLA-DR4 binds citrullinated self-antigens and the TCR.
Sci Immunol, 6, 2021
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6V18
 | | immune receptor complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fibrinogen beta, GLYCEROL, ... | | 著者 | Lim, J.J, Rossjohn, J. | | 登録日 | 2019-11-20 | | 公開日 | 2020-11-25 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | The shared susceptibility epitope of HLA-DR4 binds citrullinated self-antigens and the TCR.
Sci Immunol, 6, 2021
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4FQX
 | | Crystal structure of HLA-DM bound to HLA-DR1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DM alpha chain, ... | | 著者 | Sethi, D.K, Pos, W, Wucherpfennig, K.W. | | 登録日 | 2012-06-25 | | 公開日 | 2013-01-09 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.599 Å) | | 主引用文献 | Crystal Structure of the HLA-DM-HLA-DR1 Complex Defines Mechanisms for Rapid Peptide Selection.
Cell(Cambridge,Mass.), 151, 2012
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2G9H
 | | Crystal Structure of Staphylococcal Enterotoxin I (SEI) in Complex with a Human MHC class II Molecule | | 分子名称: | 1,4-DIETHYLENE DIOXIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HLA class II histocompatibility antigen, ... | | 著者 | Fernandez, M.M, Guan, R, Malchiodi, E.L, Mariuzza, R.A. | | 登録日 | 2006-03-06 | | 公開日 | 2006-07-11 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of staphylococcal enterotoxin I (SEI) in complex with a human major histocompatibility complex class II molecule.
J.Biol.Chem., 281, 2006
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8EUQ
 | | Crystal structure of HLA-DRA*01:01/HLA-DRB1*04:01 in complex with c44H10 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, ... | | 著者 | Kassardjian, A, Julien, J.-P. | | 登録日 | 2022-10-19 | | 公開日 | 2023-04-19 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.09 Å) | | 主引用文献 | Modular adjuvant-free pan-HLA-DR-immunotargeting subunit vaccine against SARS-CoV-2 elicits broad sarbecovirus-neutralizing antibody responses.
Cell Rep, 42, 2023
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9FTI
 | | Open conformation of the pentameric ligand-gated ion channel, DeCLIC at pH 5 with 10mM EDTA | | 分子名称: | Neurotransmitter-gated ion-channel ligand-binding domain-containing protein | | 著者 | Rovsnik, U, Anden, O, Lycksell, M, Delarue, M, Howard, R.J, Lindahl, E. | | 登録日 | 2024-06-24 | | 公開日 | 2024-09-11 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structural characterization of pH-modulated closed and open states
in a pentameric ligand-gated ion channel
To Be Published
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9FTJ
 | | Closed and disordered conformation of the pentameric ligand-gated ion channel, DeCLIC at pH 5 with 10mM EDTA | | 分子名称: | Neurotransmitter-gated ion-channel ligand-binding domain-containing protein | | 著者 | Rovsnik, U, Anden, O, Lycksell, M, Delarue, M, Howard, R.J, Lindahl, E. | | 登録日 | 2024-06-24 | | 公開日 | 2024-09-11 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structural characterization of pH-modulated closed and open states
in a pentameric ligand-gated ion channel
To Be Published
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9FTG
 | | Closed conformation of the pentameric ligand-gated ion channel, DeCLIC at pH 5 with 10 mM Ca2+ | | 分子名称: | CALCIUM ION, Neurotransmitter-gated ion-channel ligand-binding domain-containing protein | | 著者 | Rovsnik, U, Anden, O, Lycksell, M, Delarue, M, Howard, R.J, Lindahl, E. | | 登録日 | 2024-06-24 | | 公開日 | 2024-09-11 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural characterization of pH-modulated closed and open states
in a pentameric ligand-gated ion channel
To Be Published
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9FTH
 | | Open conformation of the pentameric ligand-gated ion channel, DeCLIC at pH 5 with 10mM Ca2+ | | 分子名称: | Neurotransmitter-gated ion-channel ligand-binding domain-containing protein | | 著者 | Rovsnik, U, Anden, O, Lycksell, M, Delarue, M, Howard, R.J, Lindahl, E. | | 登録日 | 2024-06-24 | | 公開日 | 2024-09-11 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural characterization of pH-modulated closed and open states
in a pentameric ligand-gated ion channel
To Be Published
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1P7Q
 | | Crystal Structure of HLA-A2 Bound to LIR-1, a Host and Viral MHC Receptor | | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... | | 著者 | Willcox, B.E, Thomas, L.M, Bjorkman, P.J. | | 登録日 | 2003-05-05 | | 公開日 | 2003-10-14 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Crystal structure of HLA-A2 bound to LIR-1, a host and viral major histocompatibility complex receptor.
Nat.Immunol., 4, 2003
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3R69
 | | Molecular analysis of the interaction of the HDL-receptor SR-BI with the PDZ3 domain of its adaptor protein PDZK1 | | 分子名称: | CITRIC ACID, Na(+)/H(+) exchange regulatory cofactor NHE-RF3, Scavenger receptor class B member 1 | | 著者 | Kocher, O, Birrane, G, Krieger, M. | | 登録日 | 2011-03-21 | | 公開日 | 2011-05-18 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.499 Å) | | 主引用文献 | Identification of the PDZ3 Domain of the Adaptor Protein PDZK1 as a Second, Physiologically Functional Binding Site for the C Terminus of the High Density Lipoprotein Receptor Scavenger Receptor Class B Type I.
J.Biol.Chem., 286, 2011
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4E41
 | | Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor G4 | | 分子名称: | HLA class II histocompatibility antigen, DR alpha chain, DRB1-1 beta chain, ... | | 著者 | Deng, L, Langley, R.J, Wang, Q, Topalian, S.L, Mariuzza, R.A. | | 登録日 | 2012-03-11 | | 公開日 | 2012-08-29 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor G4
Proc.Natl.Acad.Sci.USA, 2012
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6F1T
 | | Cryo-EM structure of two dynein tail domains bound to dynactin and BICDR1 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ARP1 actin related protein 1 homolog A, ... | | 著者 | Urnavicius, L, Lau, C.K, Elshenawy, M.M, Morales-Rios, E, Motz, C, Yildiz, A, Carter, A.P. | | 登録日 | 2017-11-23 | | 公開日 | 2018-01-17 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Cryo-EM shows how dynactin recruits two dyneins for faster movement.
Nature, 554, 2018
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6F3A
 | | Cryo-EM structure of a single dynein tail domain bound to dynactin and BICD2N | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ARP1 actin related protein 1 homolog A, ... | | 著者 | Urnavicius, L, Lau, C.K, Elshenawy, M.M, Morales-Rios, E, Motz, C, Yildiz, A, Carter, A.P. | | 登録日 | 2017-11-28 | | 公開日 | 2018-01-17 | | 最終更新日 | 2019-12-11 | | 実験手法 | ELECTRON MICROSCOPY (8.2 Å) | | 主引用文献 | Cryo-EM shows how dynactin recruits two dyneins for faster movement.
Nature, 554, 2018
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6F38
 | | Cryo-EM structure of two dynein tail domains bound to dynactin and HOOK3 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ARP1 actin related protein 1 homolog A, ... | | 著者 | Lau, C.K, Urnavicius, L, Elshenawy, M.M, Morales-Rios, E, Motz, C, Yildiz, A, Carter, A.P. | | 登録日 | 2017-11-28 | | 公開日 | 2018-01-17 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (6.7 Å) | | 主引用文献 | Cryo-EM shows how dynactin recruits two dyneins for faster movement.
Nature, 554, 2018
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6F1Z
 | | Roadblock-1 region of the dynein tail/dynactin/BICDR1 complex | | 分子名称: | Cytoplasmic dynein 1 intermediate chain 2, Dynein light chain roadblock-type 1 | | 著者 | Urnavicius, L, Lau, C.K, Elshenawy, M.M, Morales-Rios, E, Motz, C, Yildiz, A, Carter, A.P. | | 登録日 | 2017-11-23 | | 公開日 | 2018-01-17 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Cryo-EM shows how dynactin recruits two dyneins for faster movement.
Nature, 554, 2018
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6QZD
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