7WYY
 
 | | Cryo-EM structure of Na+,K+-ATPase in the E2P state formed by inorganic phosphate with istaroxime | | 分子名称: | (3E,5S,8R,9S,10R,13S,14S)-3-(2-azanylethoxyimino)-10,13-dimethyl-1,2,4,5,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-6,17-dione, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Kanai, R, Cornelius, F, Vilsen, B, Toyoshima, C. | | 登録日 | 2022-02-16 | | 公開日 | 2022-04-27 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Cryoelectron microscopy of Na + ,K + -ATPase in the two E2P states with and without cardiotonic steroids.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7WYU
 | | Cryo-EM structure of Na+,K+-ATPase in the E2P state formed by ATP | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Kanai, R, Cornelius, F, Vilsen, B, Toyoshima, C. | | 登録日 | 2022-02-16 | | 公開日 | 2022-04-27 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Cryoelectron microscopy of Na + ,K + -ATPase in the two E2P states with and without cardiotonic steroids.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7WYV
 | | Cryo-EM structure of Na+,K+-ATPase in the E2P state formed by ATP in the presence of 40 mM Mg2+ | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Kanai, R, Cornelius, F, Vilsen, B, Toyoshima, C. | | 登録日 | 2022-02-16 | | 公開日 | 2022-04-27 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Cryoelectron microscopy of Na + ,K + -ATPase in the two E2P states with and without cardiotonic steroids.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7X23
 | | Cryo-EM structure of non gastric H,K-ATPase alpha2 SPWC mutant in 3Na+E1-AMPPCPF state | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Potassium-transporting ATPase alpha chain 2, ... | | 著者 | Abe, K, Nakanishi, H, Young, V, Artigas, P. | | 登録日 | 2022-02-25 | | 公開日 | 2022-10-05 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structure and function of H + /K + pump mutants reveal Na + /K + pump mechanisms.
Nat Commun, 13, 2022
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7W7W
 | | E2 Pi of SERCA2b | | 分子名称: | MAGNESIUM ION, Sarcoplasmic/endoplasmic reticulum calcium ATPase 2, TETRAFLUOROALUMINATE ION | | 著者 | Zhang, Y, Watanabe, S, Tsutsumi, A, Inaba, K. | | 登録日 | 2021-12-06 | | 公開日 | 2022-12-14 | | 最終更新日 | 2023-01-11 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Multiple sub-state structures of SERCA2b reveal conformational overlap at transition steps during the catalytic cycle.
Cell Rep, 41, 2022
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7W7T
 | | The E1-BeF3- 2Ca2+ of SERCA2b | | 分子名称: | BERYLLIUM TRIFLUORIDE ION, CALCIUM ION, MAGNESIUM ION, ... | | 著者 | Zhang, Y, Watanabe, S, Tsutsumi, A, Inaba, K. | | 登録日 | 2021-12-06 | | 公開日 | 2022-12-14 | | 最終更新日 | 2023-01-11 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Multiple sub-state structures of SERCA2b reveal conformational overlap at transition steps during the catalytic cycle.
Cell Rep, 41, 2022
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7W7U
 | | The 'Ca2+-unbound' BeF3- of SERCA2b | | 分子名称: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | | 著者 | Zhang, Y, Watanabe, S, Tsutsumi, A, Inaba, K. | | 登録日 | 2021-12-06 | | 公開日 | 2022-12-14 | | 最終更新日 | 2023-01-11 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Multiple sub-state structures of SERCA2b reveal conformational overlap at transition steps during the catalytic cycle.
Cell Rep, 41, 2022
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7W7V
 | | 'late' E2P of SERCA2b | | 分子名称: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | | 著者 | Zhang, Y, Watanabe, S, Tsutsumi, A, Inaba, K. | | 登録日 | 2021-12-06 | | 公開日 | 2022-12-14 | | 最終更新日 | 2023-01-11 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Multiple sub-state structures of SERCA2b reveal conformational overlap at transition steps during the catalytic cycle.
Cell Rep, 41, 2022
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7Y45
 | | Cryo-EM structure of the Na+,K+-ATPase in the E2.2K+ state | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Kanai, R, Cornelius, F, Vilsen, B, Toyoshima, C. | | 登録日 | 2022-06-14 | | 公開日 | 2022-07-13 | | 最終更新日 | 2022-10-19 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Cryo-electron microscopy of Na + ,K + -ATPase reveals how the extracellular gate locks in the E2·2K + state.
Febs Lett., 596, 2022
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7Y46
 | | Cryo-EM structure of the Na+,K+-ATPase in the E2.2K+ state after addition of ATP | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Kanai, R, Cornelius, F, Vilsen, B, Toyoshima, C. | | 登録日 | 2022-06-14 | | 公開日 | 2022-07-13 | | 最終更新日 | 2022-10-19 | | 実験手法 | ELECTRON MICROSCOPY (7.2 Å) | | 主引用文献 | Cryo-electron microscopy of Na + ,K + -ATPase reveals how the extracellular gate locks in the E2·2K + state.
Febs Lett., 596, 2022
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7VGH
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7VGJ
 | | Cryo-EM structure of the human P4-type flippase ATP8B1-CDC50A in the auto-inhibited E2Pi-PS state | | 分子名称: | Cell cycle control protein 50A, O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine, Phospholipid-transporting ATPase IC | | 著者 | Chen, M.T, Chen, Y, Chen, Z.P, Zhou, C.Z, Hou, W.T, Chen, Y. | | 登録日 | 2021-09-16 | | 公開日 | 2022-03-30 | | 最終更新日 | 2022-10-12 | | 実験手法 | ELECTRON MICROSCOPY (3.98 Å) | | 主引用文献 | Structural insights into the activation of autoinhibited human lipid flippase ATP8B1 upon substrate binding.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7VGI
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7YAM
 | | CryoEM structure of SPCA1a in E2P state | | 分子名称: | BERYLLIUM TRIFLUORIDE ION, Calcium-transporting ATPase type 2C member 1, MAGNESIUM ION | | 著者 | Chen, Z, Watanabe, S, Inaba, K. | | 登録日 | 2022-06-28 | | 公開日 | 2023-03-22 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Cryo-EM structures of human SPCA1a reveal the mechanism of Ca 2+ /Mn 2+ transport into the Golgi apparatus.
Sci Adv, 9, 2023
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7YAJ
 | | CryoEM structure of SPCA1a in E1-Mn-AMPPCP state subclass 1 | | 分子名称: | Calcium-transporting ATPase type 2C member 1, MANGANESE (II) ION, Nanobody head piece of megabody, ... | | 著者 | Chen, Z, Watanabe, S, Inaba, K. | | 登録日 | 2022-06-28 | | 公開日 | 2023-03-22 | | 実験手法 | ELECTRON MICROSCOPY (3.16 Å) | | 主引用文献 | Cryo-EM structures of human SPCA1a reveal the mechanism of Ca 2+ /Mn 2+ transport into the Golgi apparatus.
Sci Adv, 9, 2023
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7YAI
 | | CryoEM structure of SPCA1a in E1-Ca-AMPPCP state subclass 3 | | 分子名称: | CALCIUM ION, Calcium-transporting ATPase type 2C member 1, Nanobody head piece of megabody, ... | | 著者 | Chen, Z, Watanabe, S, Inaba, K. | | 登録日 | 2022-06-28 | | 公開日 | 2023-03-22 | | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | | 主引用文献 | Cryo-EM structures of human SPCA1a reveal the mechanism of Ca 2+ /Mn 2+ transport into the Golgi apparatus.
Sci Adv, 9, 2023
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7YAH
 | | CryoEM structure of SPCA1a in E1-Ca-AMPPCP state subclass 2 | | 分子名称: | CALCIUM ION, Calcium-transporting ATPase type 2C member 1, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | | 著者 | Chen, Z, Watanabe, S, Inaba, K. | | 登録日 | 2022-06-28 | | 公開日 | 2023-03-22 | | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | | 主引用文献 | Cryo-EM structures of human SPCA1a reveal the mechanism of Ca 2+ /Mn 2+ transport into the Golgi apparatus.
Sci Adv, 9, 2023
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7YAG
 | | CryoEM structure of SPCA1a in E1-Ca-AMPPCP state subclass 1 | | 分子名称: | CALCIUM ION, Calcium-transporting ATPase type 2C member 1, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | | 著者 | Chen, Z, Watanabe, S, Inaba, K. | | 登録日 | 2022-06-28 | | 公開日 | 2023-03-22 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Cryo-EM structures of human SPCA1a reveal the mechanism of Ca 2+ /Mn 2+ transport into the Golgi apparatus.
Sci Adv, 9, 2023
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7W4A
 | | Cryo-EM structure of the gastric proton pump complexed with revaprazan | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, ... | | 著者 | Abe, K, Tanaka, S, Morita, M, Yamagishi, T. | | 登録日 | 2021-11-26 | | 公開日 | 2022-03-02 | | 最終更新日 | 2022-07-20 | | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | | 主引用文献 | Structural Basis for Binding of Potassium-Competitive Acid Blockers to the Gastric Proton Pump.
J.Med.Chem., 65, 2022
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7XUK
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7XUO
 | | Structure of ATP7B C983S/C985S/D1027A mutant with cisplatin in presence of ATOX1 | | 分子名称: | Copper-transporting ATPase 2, PLATINUM (II) ION | | 著者 | Yang, G, Xu, L, Chang, S, Guo, J, Wu, Z. | | 登録日 | 2022-05-19 | | 公開日 | 2023-04-26 | | 最終更新日 | 2023-05-03 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structures of the human Wilson disease copper transporter ATP7B.
Cell Rep, 42, 2023
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7XUN
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7XUM
 | | Structure of ATP7B C983S/C985S/D1027A mutant with Cu+ in presence of ATOX1 | | 分子名称: | COPPER (II) ION, Copper-transporting ATPase 2 | | 著者 | Yang, G, Xu, L, Chang, S, Guo, J, Wu, Z. | | 登録日 | 2022-05-19 | | 公開日 | 2023-05-03 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structures of the human Wilson disease copper transporter ATP7B.
Cell Rep, 42, 2023
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7X20
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7X22
 | | Cryo-EM structure of non gastric H,K-ATPase alpha2 K794S in (2K+)E2-AlF state | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | | 著者 | Nakanishi, H, Abe, K. | | 登録日 | 2022-02-25 | | 公開日 | 2022-10-05 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structure and function of H + /K + pump mutants reveal Na + /K + pump mechanisms.
Nat Commun, 13, 2022
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