PDB: 45853 件ウェブページステータス検索Chemie searchBIRD

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5M8T	Crystal structure of human tyrosinase related protein 1 (T391V-R374S-Y362F) in complex with tropolone 分子名称: 2-HYDROXYCYCLOHEPTA-2,4,6-TRIEN-1-ONE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Lai, X, Soler-Lopez, M, Wichers, H.J, Dijkstra, B.W. 登録日 2016-10-29 公開日 2017-07-12 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structure of Human Tyrosinase Related Protein 1 Reveals a Binuclear Zinc Active Site Important for Melanogenesis. Angew. Chem. Int. Ed. Engl., 56, 2017
5M9C	Human angiogenin ALS variant K40R 分子名称: Angiogenin, D(-)-TARTARIC ACID, DI(HYDROXYETHYL)ETHER 著者 Bradshaw, W.J, Rehman, S, Pham, T.T.K, Thiyagarajan, N, Lee, R.L, Subramanian, V, Acharya, K.R. 登録日 2016-11-01 公開日 2017-02-22 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural insights into human angiogenin variants implicated in Parkinson's disease and Amyotrophic Lateral Sclerosis. Sci Rep, 7, 2017
5M9J	Human angiogenin PD variant K60E 分子名称: Angiogenin, L(+)-TARTARIC ACID 著者 Bradshaw, W.J, Rehman, S, Pham, T.T.K, Thiyagarajan, N, Lee, R.L, Subramanian, V, Acharya, K.R. 登録日 2016-11-01 公開日 2017-02-22 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural insights into human angiogenin variants implicated in Parkinson's disease and Amyotrophic Lateral Sclerosis. Sci Rep, 7, 2017
6R6G	Structure of XBP1u-paused ribosome nascent chain complex with SRP. 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... 著者 Shanmuganathan, V, Cheng, J, Braunger, K, Berninghausen, O, Beatrix, B, Beckmann, R. 登録日 2019-03-27 公開日 2019-07-10 最終更新日 2019-10-30 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural and mutational analysis of the ribosome-arresting human XBP1u. Elife, 8, 2019
6RCW	Crystal structure of human phosphodiesterase 4D2 catalytic domain with inhibitor NPD-053 分子名称: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 3-[5-[(4~{a}~{R},8~{a}~{S})-3-cycloheptyl-4-oxidanylidene-4~{a},5,8,8~{a}-tetrahydrophthalazin-1-yl]-2-methoxy-phenyl]-~{N}-(furan-2-ylmethyl)prop-2-ynamide, ... 著者 Singh, A.K, Brown, D.G. 登録日 2019-04-11 公開日 2019-07-24 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Alkynamide phthalazinones as a new class of TbrPDEB1 inhibitors (Part 2). Bioorg.Med.Chem., 27, 2019
6B55	Crystal structure of the Plant Defensin NaD1 complexed with phosphatidic acid 分子名称: 1,2-DIOCTANOYL-SN-GLYCERO-3-PHOSPHATE, 1,2-ETHANEDIOL, Flower-specific defensin, ... 著者 Jarva, M, Phan, K, Humble, C, Lay, F.T, Hulett, M, Kvansakul, M. 登録日 2017-09-28 公開日 2018-05-23 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 X-ray structure of a carpet-like antimicrobial defensin-phospholipid membrane disruption complex. Nat Commun, 9, 2018
6RE6	Cryo-EM structure of Polytomella F-ATP synthase, Rotary substate 2C, monomer-masked refinement 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ASA-10: Polytomella F-ATP synthase associated subunit 10, ... 著者 Murphy, B.J, Klusch, N, Yildiz, O, Kuhlbrandt, W. 登録日 2019-04-12 公開日 2019-07-03 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Rotary substates of mitochondrial ATP synthase reveal the basis of flexible F 1 -F o coupling. Science, 364, 2019
6HUB	Yeast 20S proteasome with human beta2c (S171G) in complex with 16 分子名称: (2~{S})-~{N}-[(2~{S},3~{R})-1-[[(2~{S})-1-[4-(aminomethyl)phenyl]-4-methylsulfonyl-butan-2-yl]amino]-3-oxidanyl-1-oxidanylidene-butan-2-yl]-2-[[(2~{R})-2-azido-3-phenyl-propanoyl]amino]-4-methyl-pentanamide, CHLORIDE ION, MAGNESIUM ION, ... 著者 Huber, E.M, Groll, M. 登録日 2018-10-05 公開日 2019-01-30 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits. J.Med.Chem., 62, 2019
4QII	Crystal Structure of type II MenB from Mycobacteria tuberculosis 分子名称: 1,4-Dihydroxy-2-naphthoyl-CoA synthase, Salicylyl CoA, TRIETHYLENE GLYCOL 著者 Song, H.G, Tse, Y.S, Sung, H.P, Guo, Z.H. 登録日 2014-05-31 公開日 2014-11-19 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Ligand-dependent active-site closure revealed in the crystal structure of Mycobacterium tuberculosis MenB complexed with product analogues Acta Crystallogr.,Sect.D, 70, 2014
6HVT	Yeast 20S proteasome with human beta2i (1-53) in complex with 20 分子名称: CHLORIDE ION, MAGNESIUM ION, Probable proteasome subunit alpha type-7, ... 著者 Huber, E.M, Groll, M. 登録日 2018-10-11 公開日 2019-01-30 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits. J.Med.Chem., 62, 2019
6HWA	Yeast 20S proteasome in complex with 43 分子名称: (2~{S})-~{N}-[(2~{S},3~{R})-1-[(4~{a}~{S},8~{a}~{S})-1,2,3,4,4~{a},5,6,7,8,8~{a}-decahydronaphthalen-2-yl]-4-methyl-3,4-bis(oxidanyl)pentan-2-yl]-3-(4-methoxyphenyl)-2-[[(2~{S})-2-(2-morpholin-4-ylethanoylamino)propanoyl]amino]propanamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ... 著者 Huber, E.M, Groll, M. 登録日 2018-10-11 公開日 2019-01-30 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits. J.Med.Chem., 62, 2019
4QLQ	yCP in complex with tripeptidic epoxyketone inhibitor 8 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, N-(morpholin-4-ylacetyl)-L-alanyl-N-[(2S,4R)-1-cyclohexyl-5-hydroxy-4-methyl-3-oxopentan-2-yl]-O-methyl-L-tyrosinamide, ... 著者 De Bruin, G, Huber, E, Xin, B, Van Rooden, E, Al-Ayed, K, Kim, K, Kisselev, A, Driessen, C, Van der Marel, G, Groll, M, Overkleeft, H. 登録日 2014-06-13 公開日 2014-07-23 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure-based design of beta 1i or beta 5i specific inhibitors of human immunoproteasomes J.Med.Chem., 57, 2014
5MF3	NMR solution structure of Harzianin HK-VI in SDS micelles 分子名称: Harzianin HK-VI 著者 Kara, S, Zamora-Carreras, H, Afonin, S, Grage, S.L, Ulrich, A.S, Jimenez, M.A. 登録日 2016-11-17 公開日 2018-06-13 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 11-mer peptaibol Harzianin HK-VI: conformational and biological analysis To Be Published
4XIW	Carbonic anhydrase Cah3 from Chlamydomonas reinhardtii in complex with acetazolamide 分子名称: 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, Carbonic anhydrase, alpha type, ... 著者 Hainzl, T, Grundstrom, C, Benlloch, R, Shevela, D, Shutova, T, Messinger, J, Samuelsson, G, Sauer-Eriksson, A.E. 登録日 2015-01-07 公開日 2015-02-11 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal Structure and Functional Characterization of Photosystem II-Associated Carbonic Anhydrase CAH3 in Chlamydomonas reinhardtii. Plant Physiol., 167, 2015
5MFE	Designed armadillo repeat protein YIIIM5AII in complex with (RR)4 peptide 分子名称: (RR)4, 1,2-ETHANEDIOL, CALCIUM ION, ... 著者 Hansen, S, Ernst, P, Reichen, C, Ewald, C, Mittl, P, Plueckthun, A. 登録日 2016-11-18 公開日 2017-09-13 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Curvature of designed armadillo repeat proteins allows modular peptide binding. J. Struct. Biol., 201, 2018
5MFM	Designed armadillo repeat protein peptide fusion YIIIM6AII_GS11_(KR)5 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, Importin subunit alpha, ... 著者 Hansen, S, Ernst, P, Reichen, C, Ewald, C, Mittl, P, Plueckthun, A. 登録日 2016-11-18 公開日 2017-09-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Curvature of designed armadillo repeat proteins allows modular peptide binding. J. Struct. Biol., 201, 2018
6REE	Cryo-EM structure of Polytomella F-ATP synthase, Rotary substate 3B, composite map 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ASA-10: Polytomella F-ATP synthase associated subunit 10, ... 著者 Murphy, B.J, Klusch, N, Yildiz, O, Kuhlbrandt, W. 登録日 2019-04-12 公開日 2019-07-03 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Rotary substates of mitochondrial ATP synthase reveal the basis of flexible F 1 -F o coupling. Science, 364, 2019
6HTD	Yeast 20S proteasome with human beta2c (S171G) in complex with 4 分子名称: (2~{S})-~{N}-[(2~{S})-1-[[(2~{S})-1-[4-(aminomethyl)phenyl]-4-methylsulfonyl-butan-2-yl]amino]-1-oxidanylidene-propan-2-yl]-2-[[(2~{S})-2-azido-3-phenyl-propanoyl]amino]-4-methyl-pentanamide, CHLORIDE ION, MAGNESIUM ION, ... 著者 Huber, E.M, Groll, M. 登録日 2018-10-03 公開日 2019-01-30 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits. J.Med.Chem., 62, 2019
6B4O	1.73 Angstrom Resolution Crystal Structure of Glutathione Reductase from Enterococcus faecalis in Complex with FAD 分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, Glutathione reductase, ... 著者 Minasov, G, Warwzak, Z, Shuvalova, L, Dubrovska, I, Cardona-Correa, A, Grimshaw, S, Kwon, K, Anderson, W.F, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2017-09-27 公開日 2017-10-11 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 1.73 Angstrom Resolution Crystal Structure of Glutathione Reductase from Enterococcus faecalis in Complex with FAD. To Be Published
6RDI	Cryo-EM structure of Polytomella F-ATP synthase, Rotary substate 1A, monomer-masked refinement 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ASA-10: Polytomella F-ATP synthase associated subunit 10, ... 著者 Murphy, B.J, Klusch, N, Yildiz, O, Kuhlbrandt, W. 登録日 2019-04-12 公開日 2019-07-03 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Rotary substates of mitochondrial ATP synthase reveal the basis of flexible F 1 -F o coupling. Science, 364, 2019
4Q3O	Crystal structure of MGS-MT1, an alpha/beta hydrolase enzyme from a Lake Matapan deep-sea metagenome library 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, GLYCEROL, ... 著者 Stogios, P.J, Xu, X, Cui, H, Alcaide, M, Ferrer, M, Savchenko, A. 登録日 2014-04-11 公開日 2015-03-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Pressure adaptation is linked to thermal adaptation in salt-saturated marine habitats. Environ Microbiol, 17, 2015
6HUU	Yeast 20S proteasome with human beta2c (S171G) in complex with 29 分子名称: CHLORIDE ION, MAGNESIUM ION, Probable proteasome subunit alpha type-7, ... 著者 Huber, E.M, Groll, M. 登録日 2018-10-09 公開日 2019-01-30 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits. J.Med.Chem., 62, 2019
6HVW	Yeast 20S proteasome with human beta2i (1-53) in complex with 43 分子名称: (2~{S})-~{N}-[(2~{S},3~{R})-1-[(4~{a}~{S},8~{a}~{S})-1,2,3,4,4~{a},5,6,7,8,8~{a}-decahydronaphthalen-2-yl]-4-methyl-3,4-bis(oxidanyl)pentan-2-yl]-3-(4-methoxyphenyl)-2-[[(2~{S})-2-(2-morpholin-4-ylethanoylamino)propanoyl]amino]propanamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ... 著者 Huber, E.M, Groll, M. 登録日 2018-10-11 公開日 2019-01-30 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits. J.Med.Chem., 62, 2019
6HWF	Yeast 20S proteasome beta2-G45A mutant in complex with ONX 0914 分子名称: (2~{S})-3-(4-methoxyphenyl)-~{N}-[(2~{S},3~{R})-4-methyl-3,4-bis(oxidanyl)-1-phenyl-pentan-2-yl]-2-[[(2~{S})-2-(2-morpholin-4-ylethanoylamino)propanoyl]amino]propanamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ... 著者 Huber, E.M, Groll, M. 登録日 2018-10-11 公開日 2019-01-30 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits. J.Med.Chem., 62, 2019
6HXX	Potato virus Y 分子名称: Coat protein, RNA (5'-R(P*UP*UP*UP*UP*U)-3') 著者 Podobnik, M, Kezar, A, Novacek, J, Polak, M. 登録日 2018-10-18 公開日 2019-08-07 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structural basis for the multitasking nature of the potato virus Y coat protein. Sci Adv, 5, 2019

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