PDB: 243083 件ウェブページステータス検索Chemie searchBIRD

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4GA3	Crystal Structure of Human Farnesyl Diphosphate Synthase in Complex with BPH-1260 分子名称: 1-butyl-3-(2-hydroxy-2,2-diphosphonoethyl)-1H-imidazol-3-ium, Farnesyl pyrophosphate synthase, MAGNESIUM ION, ... 著者 Liu, Y.-L, Zhang, Y, Oldfield, E. 登録日 2012-07-24 公開日 2013-05-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 Chemo-Immunotherapeutic Anti-Malarials Targeting Isoprenoid Biosynthesis. ACS MED.CHEM.LETT., 4, 2013
4KES	Crystal structure of SsoPox W263T 分子名称: 1,2-ETHANEDIOL, Aryldialkylphosphatase, COBALT (II) ION, ... 著者 Gotthard, G, Hiblot, J, Chabriere, E, Elias, M. 登録日 2013-04-26 公開日 2013-10-02 最終更新日 2025-03-26 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Differential Active Site Loop Conformations Mediate Promiscuous Activities in the Lactonase SsoPox. Plos One, 8, 2013
2ZCS	Crystal structure of the C(30) carotenoid dehydrosqualene synthase from Staphylococcus aureus complexed with bisphosphonate BPH-700 分子名称: Dehydrosqualene synthase, tripotassium (1R)-4-biphenyl-4-yl-1-phosphonatobutane-1-sulfonate 著者 Liu, C.I, Jeng, W.Y, Wang, A.H, Oldfield, E. 登録日 2007-11-11 公開日 2008-03-11 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence. Science, 319, 2008
4GCO	Central domain of stress-induced protein-1 (STI-1) from C.elegans 分子名称: Protein STI-1 著者 Osipiuk, J, Bigelow, L, Gu, M, Van Oosten-Hawle, P, Morimoto, R.I, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2012-07-30 公開日 2012-08-15 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Central domain of stress-induced protein-1 (STI-1) from C.elegans To be Published
2ZGX	Thrombin Inhibition 分子名称: 1-[(2R)-2-aminobutanoyl]-N-(4-carbamimidoylbenzyl)-L-prolinamide, Hirudin variant-1, SODIUM ION, ... 著者 Baum, B, Heine, A, Klebe, G. 登録日 2008-01-28 公開日 2008-12-16 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Think twice: understanding the high potency of bis(phenyl)methane inhibitors of thrombin J.Mol.Biol., 391, 2009
1UWG	Molecular Mechanism of Enantioselective Proton Transfer to Carbon in Catalytic Antibody 14D9 分子名称: 1-(4-{[(2-HYDROXYETHYL)AMINO]CARBONYL}BENZYL)-1-METHYLPIPERIDINIUM, ANTIBODY 14D9, PHOSPHATE ION 著者 Baumann, U, Reymond, J.L. 登録日 2004-02-05 公開日 2004-02-27 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Molecular Mechanism of Enantioselective Proton Transfer to Carbon in Catalytic Antibody 14D9 Proc.Natl.Acad.Sci.USA, 101, 2004
1ZXY	Anthranilate Phosphoribosyltransferase from Sulfolobus solfataricus in complex with PRPP and Magnesium 分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Anthranilate phosphoribosyltransferase, MAGNESIUM ION 著者 Marino, M, Deuss, M, Sterner, R, Mayans, O. 登録日 2005-06-09 公開日 2006-05-23 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 Structural and mutational analysis of substrate complexation by anthranilate phosphoribosyltransferase from Sulfolobus solfataricus. J.Biol.Chem., 281, 2006
5SPY	PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with REAL300019621104 分子名称: 1-(5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)-2-[(1H-tetrazol-5-yl)sulfanyl]ethan-1-one, Non-structural protein 3 著者 Correy, G.J, Fraser, J.S. 登録日 2022-06-09 公開日 2022-07-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023
4GCN	N-terminal domain of stress-induced protein-1 (STI-1) from C.elegans 分子名称: Protein STI-1, TRIETHYLENE GLYCOL 著者 Osipiuk, J, Bigelow, L, Gu, M, Van Oosten-Hawle, P, Morimoto, R.I, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2012-07-30 公開日 2012-08-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 N-terminal domain of stress-induced protein-1 (STI-1) from C.elegans To be Published
1HQN	THE SELENOMETHIONINE DERIVATIVE OF P3, THE MAJOR COAT PROTEIN OF THE LIPID-CONTAINING BACTERIOPHAGE PRD1. 分子名称: MAJOR CAPSID PROTEIN 著者 Benson, S.D, Bamford, J.K.H, Bamford, D.H, Burnett, R.M. 登録日 2000-12-18 公開日 2001-01-17 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The X-ray crystal structure of P3, the major coat protein of the lipid-containing bacteriophage PRD1, at 1.65 A resolution. Acta Crystallogr.,Sect.D, 58, 2002
4G1K	Crystal structure of triosephosphate isomerase from Burkholderia thailandensis 分子名称: 1,2-ETHANEDIOL, ACETATE ION, SODIUM ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2012-07-10 公開日 2012-07-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Combining functional and structural genomics to sample the essential Burkholderia structome. Plos One, 8, 2013
1VFQ	The Crystal Structure of Human Coactosin-like Protein at 1.9 A Resolution 分子名称: Coactosin-like protein 著者 Li, X, Liu, Y, Liu, X, Lou, Z. 登録日 2004-04-19 公開日 2005-01-25 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of human coactosin-like protein at 1.9 A resolution PROTEIN SCI., 13, 2004
2EBU	Solution structure of the BRCT domain from human replication factor C large subunit 1 分子名称: Replication factor C subunit 1 著者 Nagashima, T, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-02-09 公開日 2007-08-14 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of the BRCT domain from human replication factor C large subunit 1 To be Published
4GHL	Structural Basis for Marburg virus VP35 mediate immune evasion mechanisms 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, MAGNESIUM ION, ... 著者 Ramanan, P, Borek, D.M, Otwinowski, Z, Leung, D.W, Amarasinghe, G.K. 登録日 2012-08-07 公開日 2012-11-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Structural basis for Marburg virus VP35-mediated immune evasion mechanisms. Proc.Natl.Acad.Sci.USA, 109, 2012
1HSL	REFINED 1.89 ANGSTROMS STRUCTURE OF THE HISTIDINE-BINDING PROTEIN COMPLEXED WITH HISTIDINE AND ITS RELATIONSHIP WITH MANY OTHER ACTIVE TRANSPORT(SLASH)CHEMOSENSORY RECEPTORS 分子名称: CADMIUM ION, HISTIDINE, HISTIDINE-BINDING PROTEIN 著者 Yao, N, Trakhanov, S, Quiocho, F.A. 登録日 1994-01-03 公開日 1994-05-31 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Refined 1.89-A structure of the histidine-binding protein complexed with histidine and its relationship with many other active transport/chemosensory proteins. Biochemistry, 33, 1994
1DK4	CRYSTAL STRUCTURE OF MJ0109 GENE PRODUCT INOSITOL MONOPHOSPHATASE 分子名称: INOSITOL MONOPHOSPHATASE, PHOSPHATE ION, ZINC ION 著者 Stec, B, Yang, H, Johnson, K.A, Chen, L, Roberts, M.F. 登録日 1999-12-06 公開日 2000-11-08 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 MJ0109 is an enzyme that is both an inositol monophosphatase and the 'missing' archaeal fructose-1,6-bisphosphatase. Nat.Struct.Biol., 7, 2000
1VJV	Crystal structure of Ubiquitin carboxyl-terminal hydrolase 6 (yfr010w) from Saccharomyces cerevisiae at 1.74 A resolution 分子名称: Ubiquitin carboxyl-terminal hydrolase 6 著者 Joint Center for Structural Genomics (JCSG) 登録日 2004-03-29 公開日 2004-09-21 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Crystal structure of Ubiquitin carboxyl-terminal hydrolase 6 (yfr010w) from Saccharomyces cerevisiae at 1.74 A resolution To be published
4FT7	Crystal Structure of the CHK1 分子名称: 1-{5-bromo-2-[(3R)-3-hydroxypiperidin-1-yl]phenyl}-3-(5-cyanopyrazin-2-yl)urea, GLYCEROL, ISOPROPYL ALCOHOL, ... 著者 Kang, Y.N, Stuckey, J.A, Chang, P, Russell, A.J. 登録日 2012-06-27 公開日 2012-08-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structure of the CHK1 To be Published
1HTR	CRYSTAL AND MOLECULAR STRUCTURES OF HUMAN PROGASTRICSIN AT 1.62 ANGSTROMS RESOLUTION 分子名称: GASTRICSIN, PROGASTRICSIN (PRO SEGMENT) 著者 Moore, S.A, Sielecki, A.R, James, M.N.G. 登録日 1994-10-21 公開日 1995-01-26 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Crystal and molecular structures of human progastricsin at 1.62 A resolution. J.Mol.Biol., 247, 1995
3R6J	Crystal Structure of the Capsid P Domain from Norwalk Virus Strain Hiroshima/1999 分子名称: 1,2-ETHANEDIOL, VP1 protein 著者 Hansman, G.S, Biertumpfel, C, McLellan, J.S, Georgiev, I, Chen, L, Zhou, T, Katayama, K, Kwong, P.D. 登録日 2011-03-21 公開日 2011-05-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal structures of GII.10 and GII.12 norovirus protruding domains in complex with histo-blood group antigens reveal details for a potential site of vulnerability. J.Virol., 85, 2011
3AHH	H142A mutant of Phosphoketolase from Bifidobacterium Breve complexed with acetyl thiamine diphosphate 分子名称: 1,2-ETHANEDIOL, 2-ACETYL-THIAMINE DIPHOSPHATE, MAGNESIUM ION, ... 著者 Suzuki, R, Katayama, T, Kim, B.-J, Wakagi, T, Shoun, H, Ashida, H, Yamamoto, K, Fushinobu, S. 登録日 2010-04-22 公開日 2010-08-25 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structures of phosphoketolase: thiamine diphosphate-dependent dehydration mechanism J.Biol.Chem., 285, 2010
3RB3	Dpo4 extension ternary complex with 3'-terminal primer A base opposite the 1-methylguanine (m1g) lesion 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ... 著者 Rechkoblit, O, Patel, D.J. 登録日 2011-03-28 公開日 2011-06-15 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Implications for damage recognition during Dpo4-mediated mutagenic bypass of m1G and m3C lesions. Structure, 19, 2011
2JNR	Discovery and optimization of a natural HIV-1 entry inhibitor targeting the gp41 fusion peptide 分子名称: ENV polyprotein, VIR165 著者 Munch, J, Standker, L, Adermann, K, Schulz, A, Pohlmann, S, Chaipan, C, Biet, T, Peters, T, Meyer, B, Wilhelm, D, Lu, H, Jing, W, Jiang, S, Forssmann, W, Kirchhoff, F. 登録日 2007-02-01 公開日 2007-05-08 最終更新日 2024-11-20 実験手法 SOLUTION NMR 主引用文献 Discovery and Optimization of a Natural HIV-1 Entry Inhibitor Targeting the gp41 Fusion Peptide. Cell(Cambridge,Mass.), 129, 2007
5SS6	PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with ZINClf00000cdzal 分子名称: 1-(2-{[2-(ethylamino)-1,3-thiazole-5-carbonyl]amino}ethyl)-1H-imidazole-4-carboxylic acid, Non-structural protein 3 著者 Correy, G.J, Fraser, J.S. 登録日 2022-06-09 公開日 2022-07-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023
5SSL	PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with ZINCoj00000doMWF 分子名称: 1-[4-(cyanomethyl)phenyl]-N-(1-methyl-1H-pyrazolo[4,3-d]pyrimidin-7-yl)methanesulfonamide, Non-structural protein 3 著者 Correy, G.J, Fraser, J.S. 登録日 2022-06-09 公開日 2022-07-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023

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