1E5W
 
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1EBP
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1E8X
 | | STRUCTURAL INSIGHTS INTO PHOSHOINOSITIDE 3-KINASE ENZYMATIC MECHANISM AND SIGNALLING | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, LUTETIUM (III) ION, PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT | | 著者 | Walker, E.H, Perisic, O, Ried, C, Stephens, L, Williams, R.L. | | 登録日 | 2000-10-03 | | 公開日 | 2000-10-26 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural Determinations of Phosphoinositide 3-Kinase Inhibition by Wortmannin, Ly294002, Quercetin, Myricetin and Staurosporine
Mol.Cell, 6, 2000
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1EPT
 | | REFINED 1.8 ANGSTROMS RESOLUTION CRYSTAL STRUCTURE OF PORCINE EPSILON-TRYPSIN | | 分子名称: | CALCIUM ION, PORCINE E-TRYPSIN | | 著者 | Huang, Q, Wang, Z, Li, Y, Liu, S, Tang, Y. | | 登録日 | 1994-06-07 | | 公開日 | 1995-02-07 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Refined 1.8 A resolution crystal structure of the porcine epsilon-trypsin.
Biochim.Biophys.Acta, 1209, 1994
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1ETR
 | | REFINED 2.3 ANGSTROMS X-RAY CRYSTAL STRUCTURE OF BOVINE THROMBIN COMPLEXES FORMED WITH THE BENZAMIDINE AND ARGININE-BASED THROMBIN INHIBITORS NAPAP, 4-TAPAP AND MQPA: A STARTING POINT FOR IMPROVING ANTITHROMBOTICS | | 分子名称: | EPSILON-THROMBIN, amino{[(4S)-5-[(2R,4R)-2-carboxy-4-methylpiperidin-1-yl]-4-({[(3R)-3-methyl-1,2,3,4-tetrahydroquinolin-8-yl]sulfonyl}amino)-5-oxopentyl]amino}methaniminium | | 著者 | Bode, W, Brandstetter, H. | | 登録日 | 1992-07-06 | | 公開日 | 1994-01-31 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Refined 2.3 A X-ray crystal structure of bovine thrombin complexes formed with the benzamidine and arginine-based thrombin inhibitors NAPAP, 4-TAPAP and MQPA. A starting point for improving antithrombotics.
J.Mol.Biol., 226, 1992
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1ELF
 | | NATURE OF THE INACTIVATION OF ELASTASE BY N-PEPTIDYL-O-AROYL HYDROXYLAMINE AS A FUNCTION OF PH | | 分子名称: | (TERT-BUTYLOXYCARBONYL)-ALANYL-AMINO ETHYL-FORMAMIDE, CALCIUM ION, PORCINE PANCREATIC ELASTASE, ... | | 著者 | Ding, X, Rasmussen, B, Demuth, H.-U, Ringe, D, Steinmetz, A.C.U. | | 登録日 | 1995-03-13 | | 公開日 | 1995-07-10 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Nature of the inactivation of elastase by N-peptidyl-O-aroyl hydroxylamine as a function of pH.
Biochemistry, 34, 1995
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5GTH
 | | Native XFEL structure of photosystem II (dark dataset) | | 分子名称: | 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ... | | 著者 | Suga, M, Shen, J.R. | | 登録日 | 2016-08-20 | | 公開日 | 2017-03-15 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Light-induced structural changes and the site of O=O bond formation in PSII caught by XFEL.
Nature, 543, 2017
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1EAP
 | | CRYSTAL STRUCTURE OF A CATALYTIC ANTIBODY WITH A SERINE PROTEASE ACTIVE SITE | | 分子名称: | IGG2B-KAPPA 17E8 FAB (HEAVY CHAIN), IGG2B-KAPPA 17E8 FAB (LIGHT CHAIN), PHENYL[1-(N-SUCCINYLAMINO)PENTYL]PHOSPHONATE | | 著者 | Zhou, G.W, Guo, J, Huang, W, Scanlan, T.S, Fletterick, R.J. | | 登録日 | 1994-08-10 | | 公開日 | 1994-12-20 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structure of a catalytic antibody with a serine protease active site.
Science, 265, 1994
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1ETP
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1F14
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5H47
 | | Crystal structure of AOL complexed with 2-MeSe-Fuc | | 分子名称: | Uncharacterized protein, methyl 6-deoxy-2-Se-methyl-2-seleno-alpha-L-galactopyranoside | | 著者 | Kato, R, Nishikawa, Y, Makyio, H. | | 登録日 | 2016-10-31 | | 公開日 | 2017-01-25 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Synthesis of seleno-fucose compounds and their application to the X-ray structural determination of carbohydrate-lectin complexes using single/multi-wavelength anomalous dispersion phasing
Bioorg. Med. Chem., 25, 2017
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3A6D
 | | Creatininase complexed with 1-methylguanidine | | 分子名称: | 1-METHYLGUANIDINE, Creatinine amidohydrolase, MANGANESE (II) ION, ... | | 著者 | Nakajima, Y, Yamashita, K, Ito, K, Yoshimoto, T. | | 登録日 | 2009-08-31 | | 公開日 | 2010-02-09 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Substitution of Glu122 by glutamine revealed the function of the second water molecule as a proton donor in the binuclear metal enzyme creatininase
J.Mol.Biol., 396, 2010
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1BHS
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1B1Z
 | | STREPTOCOCCAL PYROGENIC EXOTOXIN A1 | | 分子名称: | PROTEIN (TOXIN) | | 著者 | Papageorgiou, A.C, Acharya, K.R. | | 登録日 | 1998-11-24 | | 公開日 | 1999-11-24 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | | 主引用文献 | Structural basis for the recognition of superantigen streptococcal pyrogenic exotoxin A (SpeA1) by MHC class II molecules and T-cell receptors.
EMBO J., 18, 1999
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1B2K
 | | Structural effects of monovalent anions on polymorphic lysozyme crystals | | 分子名称: | IODIDE ION, PROTEIN (LYSOZYME) | | 著者 | Vaney, M.C, Broutin, I, Ries-Kautt, M, Ducruix, A. | | 登録日 | 1998-11-26 | | 公開日 | 1998-12-02 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural effects of monovalent anions on polymorphic lysozyme crystals.
Acta Crystallogr.,Sect.D, 57, 2001
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1AY9
 | | WILD-TYPE UMUD' FROM E. COLI | | 分子名称: | UMUD PROTEIN | | 著者 | Peat, T.S, Frank, E.G, Mcdonald, J.P, Levine, A.S, Woodgate, R, Hendrickson, W.A. | | 登録日 | 1997-11-15 | | 公開日 | 1998-01-28 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | The UmuD' protein filament and its potential role in damage induced mutagenesis.
Structure, 4, 1996
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1B3R
 | | RAT LIVER S-ADENOSYLHOMOCYSTEIN HYDROLASE | | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PROTEIN (S-ADENOSYLHOMOCYSTEINE HYDROLASE) | | 著者 | Hu, Y, Komoto, J, Huang, Y, Takusagawa, F, Gomi, T, Ogawa, H, Takata, Y, Fujioka, M. | | 登録日 | 1998-12-14 | | 公開日 | 1998-12-23 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of S-adenosylhomocysteine hydrolase from rat liver.
Biochemistry, 38, 1999
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1AZ2
 | | CITRATE BOUND, C298A/W219Y MUTANT HUMAN ALDOSE REDUCTASE | | 分子名称: | ALDOSE REDUCTASE, CITRIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Harrison, D.H, Bohren, K.M, Ringe, D, Petsko, G.A, Gabbay, K.H. | | 登録日 | 1997-11-24 | | 公開日 | 1998-03-18 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | The alrestatin double-decker: binding of two inhibitor molecules to human aldose reductase reveals a new specificity determinant.
Biochemistry, 36, 1997
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1B0P
 | | CRYSTAL STRUCTURE OF PYRUVATE-FERREDOXIN OXIDOREDUCTASE FROM DESULFOVIBRIO AFRICANUS | | 分子名称: | CALCIUM ION, IRON/SULFUR CLUSTER, MAGNESIUM ION, ... | | 著者 | Chabriere, E, Charon, M.H, Volbeda, A. | | 登録日 | 1998-11-12 | | 公開日 | 1999-04-23 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Crystal structures of the key anaerobic enzyme pyruvate:ferredoxin oxidoreductase, free and in complex with pyruvate.
Nat.Struct.Biol., 6, 1999
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1B63
 | | MUTL COMPLEXED WITH ADPNP | | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, MUTL, ... | | 著者 | Yang, W. | | 登録日 | 1999-01-20 | | 公開日 | 1999-06-08 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Transformation of MutL by ATP binding and hydrolysis: a switch in DNA mismatch repair.
Cell(Cambridge,Mass.), 97, 1999
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1B3B
 | | THERMOTOGA MARITIMA GLUTAMATE DEHYDROGENASE MUTANT N97D, G376K | | 分子名称: | PROTEIN (GLUTAMATE DEHYDROGENASE) | | 著者 | Knapp, S, Lebbink, J.H.G, Van Der Oost, J, Devos, W.M, Rice, D, Ladenstein, R. | | 登録日 | 1998-12-07 | | 公開日 | 1999-12-08 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Engineering activity and stability of Thermotoga maritima glutamate dehydrogenase. I. Introduction of a six-residue ion-pair network in the hinge region.
J.Mol.Biol., 280, 1998
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1B6L
 | | HIV-1 PROTEASE COMPLEXED WITH MACROCYCLIC PEPTIDOMIMETIC INHIBITOR 4 | | 分子名称: | 1-[2-(8-CARBAMOYLMETHYL-6,9-DIOXO-2-OXA-7,10-DIAZA-BICYCLO[11.2.2]HEPTADECA- 1(16),13(17),14-TRIEN-11-YL)-2-HYDROXY-ETHYL]-PIPERIDINE-2-CARBOXYLIC ACID TERT-BUTYLAMIDE, RETROPEPSIN, SULFATE ION | | 著者 | Martin, J.L, Begun, J, Schindeler, A, Wickramasinghe, W.A, Alewood, D, Alewood, P.F, Bergman, D.A, Brinkworth, R.I, Abbenante, G, March, D.R, Reid, R.C, Fairlie, D.P. | | 登録日 | 1999-01-17 | | 公開日 | 2000-01-07 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease.
Biochemistry, 38, 1999
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1B74
 | | GLUTAMATE RACEMASE FROM AQUIFEX PYROPHILUS | | 分子名称: | D-GLUTAMINE, GLUTAMATE RACEMASE | | 著者 | Hwang, K.Y, Cho, C.S, Kim, S.S, Yu, Y.G, Cho, Y. | | 登録日 | 1999-01-27 | | 公開日 | 2000-01-28 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure and mechanism of glutamate racemase from Aquifex pyrophilus.
Nat.Struct.Biol., 6, 1999
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1B8J
 | | ALKALINE PHOSPHATASE COMPLEXED WITH VANADATE | | 分子名称: | MAGNESIUM ION, PROTEIN (ALKALINE PHOSPHATASE), SULFATE ION, ... | | 著者 | Holtz, K.M, Stec, B, Kantrowitz, E.R. | | 登録日 | 1999-02-01 | | 公開日 | 1999-02-18 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | A model of the transition state in the alkaline phosphatase reaction.
J.Biol.Chem., 274, 1999
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1B9E
 | | HUMAN INSULIN MUTANT SERB9GLU | | 分子名称: | PROTEIN (INSULIN) | | 著者 | Wang, D.C, Zeng, Z.H, Yao, Z.P, Li, H.M. | | 登録日 | 1998-11-12 | | 公開日 | 1999-11-17 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of an insulin dimer in an orthorhombic crystal: the structure analysis of a human insulin mutant (B9 Ser-->Glu).
Acta Crystallogr.,Sect.D, 55, 1999
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