PDB: 13413 件ウェブページステータス検索Chemie searchBIRD

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2BDP	CRYSTAL STRUCTURE OF BACILLUS DNA POLYMERASE I FRAGMENT COMPLEXED TO 9 BASE PAIRS OF DUPLEX DNA 分子名称: DNA (5'-D(*GP*CP*AP*TP*GP*AP*TP*GP*C)-3'), DNA (5'-D(P*AP*GP*CP*AP*TP*CP*AP*TP*GP*C)-3'), MAGNESIUM ION, ... 著者 Kiefer, J.R, Mao, C, Beese, L.S. 登録日 1997-11-17 公開日 1999-01-13 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Visualizing DNA replication in a catalytically active Bacillus DNA polymerase crystal. Nature, 391, 1998
1ZJN	Human DNA Polymerase beta complexed with DNA containing an A-A mismatched primer terminus with dGTP 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... 著者 Batra, V.K, Beard, W.A, Shock, D.D, Pedersen, L.C, Wilson, S.H. 登録日 2005-04-29 公開日 2005-08-16 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 Nucleotide-induced DNA polymerase active site motions accommodating a mutagenic DNA intermediate. STRUCTURE, 13, 2005
2V4Q	Post-insertion complex of the Y-family DNA polymerase Dpo4 with M1dG containing template DNA 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP *TP*TP*CP*C)-3', 5'-D(*TP*CP*AP*C M1GP*GP*AP*AP*TP*CP*CP *TP*TP*CP*CP*CP*CP*C)-3', ... 著者 Eoff, R.L, Stafford, J.B, Szekely, J, Rizzo, C.J, Egli, M, Guengerich, F.P, Marnett, L.J. 登録日 2008-09-26 公開日 2009-06-16 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural and Functional Analysis of Sulfolobus Solfataricus Y-Family DNA Polymerase Dpo4-Catalyzed Bypass of the Malondialdehyde-Deoxyguanosine Adduct. Biochemistry, 48, 2009
1IG9	Structure of the Replicating Complex of a Pol Alpha Family DNA Polymerase 分子名称: 5'-D(*AP*CP*AP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3', 5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*CP*(DOC))-3', CALCIUM ION, ... 著者 Franklin, M.C, Wang, J, Steitz, T.A. 登録日 2001-04-17 公開日 2001-06-11 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure of the Replicating Complex of a Pol Alpha Family DNA Polymerase Cell(Cambridge,Mass.), 105, 2001
6V8P	Structure of DNA Polymerase Zeta (Apo) 分子名称: DNA polymerase delta small subunit, DNA polymerase delta subunit 3, DNA polymerase zeta catalytic subunit, ... 著者 Malik, R, Gomez-Llorente, Y, Ubarretxena-Belandia, I, Aggarwal, A.K. 登録日 2019-12-11 公開日 2020-08-19 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Structure and mechanism of B-family DNA polymerase zeta specialized for translesion DNA synthesis. Nat.Struct.Mol.Biol., 27, 2020
1QHT	DNA POLYMERASE FROM THERMOCOCCUS SP. 9ON-7 ARCHAEON 分子名称: PROTEIN (DNA POLYMERASE) 著者 Park, H.-W, Rodriguez, A.C, Beese, L.S. 登録日 1999-05-26 公開日 2000-05-26 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of a pol alpha family DNA polymerase from the hyperthermophilic archaeon Thermococcus sp. 9 degrees N-7. J.Mol.Biol., 299, 2000
7QDZ	80S-bound human SKI complex in the closed state 分子名称: Helicase SKI2W, RNA (5'-R(P*UP*UP*UP*UP*UP*U)-3'), Tetratricopeptide repeat protein 37, ... 著者 Koegel, A, Keidel, A, Bonneau, F, Schaefer, I.B, Conti, E. 登録日 2021-12-01 公開日 2022-02-09 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism. Mol.Cell, 82, 2022
7Y18	Crystal structure of ribosomal ITS2 pre-rRNA processing complex from Saccharomyces cerevisiae 分子名称: Polynucleotide 5'-hydroxyl-kinase GRC3, Protein LAS1 著者 Chen, J, Liu, L. 登録日 2022-06-07 公開日 2023-06-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.69 Å) 主引用文献 Structural and mechanistic insights into ribosomal ITS2 RNA processing by nuclease-kinase machinery. Elife, 12, 2024
8TL1	Structure of Orthoreovirus RNA Chaperone SigmaNS N17 分子名称: GLYCOCHOLIC ACID, Protein sigma-NS 著者 Prasad, B.V.V, Zhao, B, Hu, L. 登録日 2023-07-26 公開日 2024-03-06 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3.16 Å) 主引用文献 Structure of orthoreovirus RNA chaperone sigma NS, a component of viral replication factories. Nat Commun, 15, 2024
8TKA	Structure of Orthoreovirus RNA Chaperone SigmaNS R6A mutant 分子名称: Protein sigma-NS 著者 Prasad, B.V.V, Zhao, B, Hu, L. 登録日 2023-07-25 公開日 2024-03-06 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure of orthoreovirus RNA chaperone sigma NS, a component of viral replication factories. Nat Commun, 15, 2024
8TL8	Structure of Orthoreovirus RNA Chaperone SigmaNS R6A mutant in complex with bile acid 分子名称: GLYCOCHOLIC ACID, Protein sigma-NS 著者 Prasad, B.V.V, Zhao, B, Hu, L, Neetu, N. 登録日 2023-07-26 公開日 2024-03-06 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structure of orthoreovirus RNA chaperone sigma NS, a component of viral replication factories. Nat Commun, 15, 2024
4B08	Yeast DNA polymerase alpha, Selenomethionine protein 分子名称: DNA POLYMERASE ALPHA CATALYTIC SUBUNIT A 著者 Perera, R.L, Torella, R, Klinge, S, Kilkenny, M.L, Maman, J.D, Pellegrini, L. 登録日 2012-06-29 公開日 2013-02-27 最終更新日 2013-05-01 実験手法 X-RAY DIFFRACTION (2.67 Å) 主引用文献 Mechanism for Priming DNA Synthesis by Yeast DNA Polymerase Alpha Elife, 2, 2013
4GMC	Crystal structure of HCV NS5B polymerase in complex with a thumb inhibitor 分子名称: 3-cyclohexyl-2-(furan-3-yl)-1-[2-(morpholin-4-yl)-2-oxoethyl]-N-(phenylsulfonyl)-1H-indole-6-carboxamide, NS5B polymerase, SULFATE ION 著者 Coulombe, R. 登録日 2012-08-15 公開日 2013-02-20 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Allosteric N-acetamide-indole-6-carboxylic acid thumb pocket 1 inhibitors of hepatitis C virus NS5B polymerase - Acylsulfonamides and acylsulfamides as carboxylic acid replacements Can.J.Chem., 91, 2013
3RTX	Crystal structure of mammalian capping enzyme (Mce1) and Pol II CTD complex 分子名称: GUANINE, RNA Polymerase II C-terminal domain, mRNA-capping enzyme 著者 Ghosh, A, Lima, C.D. 登録日 2011-05-04 公開日 2011-06-29 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.81 Å) 主引用文献 Structural insights to how mammalian capping enzyme reads the CTD code. Mol.Cell, 43, 2011
3EYZ	Cocrystal structure of Bacillus fragment DNA polymerase I with duplex DNA (open form) 分子名称: 5'-D(*DAP*DTP*DGP*DCP*DGP*DAP*DGP*DTP*DCP*DAP*DGP*DGP*DA)-3', 5'-D(*DCP*DCP*DTP*DGP*DAP*DCP*DTP*DCP*DGP*DC)-3', DNA polymerase I, ... 著者 Warren, J.J, Wu, E.Y, Golosov, A.A, Karplus, M, Beese, L.S. 登録日 2008-10-22 公開日 2009-11-10 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The Mechanism of the Translocation Step in DNA Replication by DNA Polymerase I: A Computer Simulation Analysis. Structure, 18, 2010
7ELL	In situ structure of capping enzyme lambda2, penetration protein mu1 of mammalian reovirus capsid asymmetric unit. 分子名称: MYRISTIC ACID, Mu1, mRNA (guanine-N(7)-)-methyltransferase 著者 Zhou, Z.H, Pan, M. 登録日 2021-04-12 公開日 2021-10-20 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Asymmetric reconstruction of mammalian reovirus reveals interactions among RNA, transcriptional factor mu2 and capsid proteins. Nat Commun, 12, 2021
7L1F	SARS-CoV-2 RdRp in complex with 4 Remdesivir monophosphate 分子名称: Non-structural protein 7, Non-structural protein 8, RNA (5'-R(P*AP*UP*UP*UP*UP*AP*AP*UP*AP*GP*CP*UP*UP*CP*UP*UP*AP*G)-3'), ... 著者 Bravo, J.P.K, Taylor, D.W. 登録日 2020-12-14 公開日 2021-02-10 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.89 Å) 主引用文献 Remdesivir is a delayed translocation inhibitor of SARS-CoV-2 replication. Mol.Cell, 81, 2021
1MFK	Structure of Prokaryotic SECIS mRNA Hairpin 分子名称: 5'-R(P*GP*GP*CP*GP*GP*UP*UP*GP*CP*AP*GP*GP*UP*CP*UP*GP*CP*AP*CP*CP*GP*CP*C)-3' 著者 Fourmy, D, Guittet, E, Yoshizawa, S. 登録日 2002-08-12 公開日 2002-11-13 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structure of Prokaryotic SECIS mRNA Hairpin and its Interaction with Elongation Factor SELB J.Mol.Biol., 324, 2002
8KG8	Yeast replisome in state II 分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, DNA (61-mer), ... 著者 Dang, S, Zhai, Y, Feng, J, Yu, D, Xu, Z. 登録日 2023-08-17 公開日 2023-12-06 実験手法 ELECTRON MICROSCOPY (4.23 Å) 主引用文献 Synergism between CMG helicase and leading strand DNA polymerase at replication fork. Nat Commun, 14, 2023
8KG9	Yeast replisome in state III 分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, DNA (61-mer), ... 著者 Dang, S, Zhai, Y, Feng, J, Yu, D, Xu, Z. 登録日 2023-08-17 公開日 2023-12-06 実験手法 ELECTRON MICROSCOPY (4.52 Å) 主引用文献 Synergism between CMG helicase and leading strand DNA polymerase at replication fork. Nat Commun, 14, 2023
8KG6	Yeast replisome in state I 分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, Chromosome segregation in meiosis protein 3, ... 著者 Dang, S, Zhai, Y, Feng, J, Yu, D, Xu, Z. 登録日 2023-08-17 公開日 2023-12-06 実験手法 ELECTRON MICROSCOPY (3.07 Å) 主引用文献 Synergism between CMG helicase and leading strand DNA polymerase at replication fork. Nat Commun, 14, 2023
7ENJ	Human Mediator (deletion of MED1-IDR) in a Tail-bent conformation (MED-B) 分子名称: Isoform 2 of Mediator of RNA polymerase II transcription subunit 8, Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, ... 著者 Yin, X, Li, J, Wu, Z, Liu, W, Xu, Y. 登録日 2021-04-17 公開日 2021-05-19 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Structures of the human Mediator and Mediator-bound preinitiation complex. Science, 372, 2021
7EMF	Human Mediator (deletion of MED1-IDR) in a Tail-extended conformation 分子名称: Isoform 2 of Mediator of RNA polymerase II transcription subunit 16, Isoform 2 of Mediator of RNA polymerase II transcription subunit 8, Mediator of RNA polymerase II transcription subunit 1, ... 著者 Yin, X, Li, J, Wu, Z, Liu, W, Xu, Y. 登録日 2021-04-13 公開日 2021-05-05 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structures of the human Mediator and Mediator-bound preinitiation complex. Science, 372, 2021
7LUF	HSV1 polymerase ternary complex with dsDNA and PNU-183792 分子名称: DNA (5'-D(*CP*GP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*TP*AP*C)-3'), DNA (5'-D(P*AP*TP*GP*GP*TP*AP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*CP*G)-3'), DNA polymerase, ... 著者 Hayes, R.P, Klein, D. 登録日 2021-02-22 公開日 2021-04-07 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Structural understanding of non-nucleoside inhibition in an elongating herpesvirus polymerase. Nat Commun, 12, 2021
8OJ6	HSV-1 DNA polymerase-processivity factor complex in pre-translocation state 分子名称: DNA (22-MER), DNA (48-MER), DNA polymerase catalytic subunit, ... 著者 Gustavsson, E, Grunewald, K, Elias, P, Hallberg, B.M. 登録日 2023-03-24 公開日 2024-04-03 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (2.41 Å) 主引用文献 Dynamics of the Herpes simplex virus DNA polymerase holoenzyme during DNA synthesis and proof-reading revealed by Cryo-EM. Nucleic Acids Res., 52, 2024

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