2BDP
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![BU of 2bdp by Molmil](/molmil-images/mine/2bdp) | CRYSTAL STRUCTURE OF BACILLUS DNA POLYMERASE I FRAGMENT COMPLEXED TO 9 BASE PAIRS OF DUPLEX DNA | 分子名称: | DNA (5'-D(*GP*CP*AP*TP*GP*AP*TP*GP*C)-3'), DNA (5'-D(P*AP*GP*CP*AP*TP*CP*AP*TP*GP*C)-3'), MAGNESIUM ION, ... | 著者 | Kiefer, J.R, Mao, C, Beese, L.S. | 登録日 | 1997-11-17 | 公開日 | 1999-01-13 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Visualizing DNA replication in a catalytically active Bacillus DNA polymerase crystal. Nature, 391, 1998
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1ZJN
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![BU of 1zjn by Molmil](/molmil-images/mine/1zjn) | Human DNA Polymerase beta complexed with DNA containing an A-A mismatched primer terminus with dGTP | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... | 著者 | Batra, V.K, Beard, W.A, Shock, D.D, Pedersen, L.C, Wilson, S.H. | 登録日 | 2005-04-29 | 公開日 | 2005-08-16 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | Nucleotide-induced DNA polymerase active site motions accommodating a mutagenic DNA intermediate. STRUCTURE, 13, 2005
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2V4Q
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![BU of 2v4q by Molmil](/molmil-images/mine/2v4q) | Post-insertion complex of the Y-family DNA polymerase Dpo4 with M1dG containing template DNA | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP *TP*TP*CP*C)-3', 5'-D(*TP*CP*AP*C M1GP*GP*AP*AP*TP*CP*CP *TP*TP*CP*CP*CP*CP*C)-3', ... | 著者 | Eoff, R.L, Stafford, J.B, Szekely, J, Rizzo, C.J, Egli, M, Guengerich, F.P, Marnett, L.J. | 登録日 | 2008-09-26 | 公開日 | 2009-06-16 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural and Functional Analysis of Sulfolobus Solfataricus Y-Family DNA Polymerase Dpo4-Catalyzed Bypass of the Malondialdehyde-Deoxyguanosine Adduct. Biochemistry, 48, 2009
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1IG9
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![BU of 1ig9 by Molmil](/molmil-images/mine/1ig9) | Structure of the Replicating Complex of a Pol Alpha Family DNA Polymerase | 分子名称: | 5'-D(*AP*CP*AP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3', 5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*CP*(DOC))-3', CALCIUM ION, ... | 著者 | Franklin, M.C, Wang, J, Steitz, T.A. | 登録日 | 2001-04-17 | 公開日 | 2001-06-11 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure of the Replicating Complex of a Pol Alpha Family DNA Polymerase Cell(Cambridge,Mass.), 105, 2001
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6V8P
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![BU of 6v8p by Molmil](/molmil-images/mine/6v8p) | Structure of DNA Polymerase Zeta (Apo) | 分子名称: | DNA polymerase delta small subunit, DNA polymerase delta subunit 3, DNA polymerase zeta catalytic subunit, ... | 著者 | Malik, R, Gomez-Llorente, Y, Ubarretxena-Belandia, I, Aggarwal, A.K. | 登録日 | 2019-12-11 | 公開日 | 2020-08-19 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structure and mechanism of B-family DNA polymerase zeta specialized for translesion DNA synthesis. Nat.Struct.Mol.Biol., 27, 2020
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1QHT
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![BU of 1qht by Molmil](/molmil-images/mine/1qht) | |
7QDZ
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![BU of 7qdz by Molmil](/molmil-images/mine/7qdz) | 80S-bound human SKI complex in the closed state | 分子名称: | Helicase SKI2W, RNA (5'-R(P*UP*UP*UP*UP*UP*U)-3'), Tetratricopeptide repeat protein 37, ... | 著者 | Koegel, A, Keidel, A, Bonneau, F, Schaefer, I.B, Conti, E. | 登録日 | 2021-12-01 | 公開日 | 2022-02-09 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism. Mol.Cell, 82, 2022
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7Y18
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![BU of 7y18 by Molmil](/molmil-images/mine/7y18) | |
8TL1
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![BU of 8tl1 by Molmil](/molmil-images/mine/8tl1) | |
8TKA
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![BU of 8tka by Molmil](/molmil-images/mine/8tka) | |
8TL8
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![BU of 8tl8 by Molmil](/molmil-images/mine/8tl8) | Structure of Orthoreovirus RNA Chaperone SigmaNS R6A mutant in complex with bile acid | 分子名称: | GLYCOCHOLIC ACID, Protein sigma-NS | 著者 | Prasad, B.V.V, Zhao, B, Hu, L, Neetu, N. | 登録日 | 2023-07-26 | 公開日 | 2024-03-06 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structure of orthoreovirus RNA chaperone sigma NS, a component of viral replication factories. Nat Commun, 15, 2024
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4B08
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![BU of 4b08 by Molmil](/molmil-images/mine/4b08) | Yeast DNA polymerase alpha, Selenomethionine protein | 分子名称: | DNA POLYMERASE ALPHA CATALYTIC SUBUNIT A | 著者 | Perera, R.L, Torella, R, Klinge, S, Kilkenny, M.L, Maman, J.D, Pellegrini, L. | 登録日 | 2012-06-29 | 公開日 | 2013-02-27 | 最終更新日 | 2013-05-01 | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | 主引用文献 | Mechanism for Priming DNA Synthesis by Yeast DNA Polymerase Alpha Elife, 2, 2013
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4GMC
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![BU of 4gmc by Molmil](/molmil-images/mine/4gmc) | Crystal structure of HCV NS5B polymerase in complex with a thumb inhibitor | 分子名称: | 3-cyclohexyl-2-(furan-3-yl)-1-[2-(morpholin-4-yl)-2-oxoethyl]-N-(phenylsulfonyl)-1H-indole-6-carboxamide, NS5B polymerase, SULFATE ION | 著者 | Coulombe, R. | 登録日 | 2012-08-15 | 公開日 | 2013-02-20 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Allosteric N-acetamide-indole-6-carboxylic acid thumb pocket 1 inhibitors of hepatitis C virus NS5B polymerase - Acylsulfonamides and acylsulfamides as carboxylic acid replacements Can.J.Chem., 91, 2013
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3RTX
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![BU of 3rtx by Molmil](/molmil-images/mine/3rtx) | |
3EYZ
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![BU of 3eyz by Molmil](/molmil-images/mine/3eyz) | Cocrystal structure of Bacillus fragment DNA polymerase I with duplex DNA (open form) | 分子名称: | 5'-D(*DAP*DTP*DGP*DCP*DGP*DAP*DGP*DTP*DCP*DAP*DGP*DGP*DA)-3', 5'-D(*DCP*DCP*DTP*DGP*DAP*DCP*DTP*DCP*DGP*DC)-3', DNA polymerase I, ... | 著者 | Warren, J.J, Wu, E.Y, Golosov, A.A, Karplus, M, Beese, L.S. | 登録日 | 2008-10-22 | 公開日 | 2009-11-10 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The Mechanism of the Translocation Step in DNA Replication by DNA Polymerase I: A Computer Simulation Analysis. Structure, 18, 2010
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7ELL
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![BU of 7ell by Molmil](/molmil-images/mine/7ell) | |
7L1F
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![BU of 7l1f by Molmil](/molmil-images/mine/7l1f) | |
1MFK
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![BU of 1mfk by Molmil](/molmil-images/mine/1mfk) | |
8KG8
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![BU of 8kg8 by Molmil](/molmil-images/mine/8kg8) | Yeast replisome in state II | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, DNA (61-mer), ... | 著者 | Dang, S, Zhai, Y, Feng, J, Yu, D, Xu, Z. | 登録日 | 2023-08-17 | 公開日 | 2023-12-06 | 実験手法 | ELECTRON MICROSCOPY (4.23 Å) | 主引用文献 | Synergism between CMG helicase and leading strand DNA polymerase at replication fork. Nat Commun, 14, 2023
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8KG9
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![BU of 8kg9 by Molmil](/molmil-images/mine/8kg9) | Yeast replisome in state III | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, DNA (61-mer), ... | 著者 | Dang, S, Zhai, Y, Feng, J, Yu, D, Xu, Z. | 登録日 | 2023-08-17 | 公開日 | 2023-12-06 | 実験手法 | ELECTRON MICROSCOPY (4.52 Å) | 主引用文献 | Synergism between CMG helicase and leading strand DNA polymerase at replication fork. Nat Commun, 14, 2023
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8KG6
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![BU of 8kg6 by Molmil](/molmil-images/mine/8kg6) | Yeast replisome in state I | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, Chromosome segregation in meiosis protein 3, ... | 著者 | Dang, S, Zhai, Y, Feng, J, Yu, D, Xu, Z. | 登録日 | 2023-08-17 | 公開日 | 2023-12-06 | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | 主引用文献 | Synergism between CMG helicase and leading strand DNA polymerase at replication fork. Nat Commun, 14, 2023
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7ENJ
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![BU of 7enj by Molmil](/molmil-images/mine/7enj) | Human Mediator (deletion of MED1-IDR) in a Tail-bent conformation (MED-B) | 分子名称: | Isoform 2 of Mediator of RNA polymerase II transcription subunit 8, Mediator of RNA polymerase II transcription subunit 1, Mediator of RNA polymerase II transcription subunit 10, ... | 著者 | Yin, X, Li, J, Wu, Z, Liu, W, Xu, Y. | 登録日 | 2021-04-17 | 公開日 | 2021-05-19 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Structures of the human Mediator and Mediator-bound preinitiation complex. Science, 372, 2021
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7EMF
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![BU of 7emf by Molmil](/molmil-images/mine/7emf) | Human Mediator (deletion of MED1-IDR) in a Tail-extended conformation | 分子名称: | Isoform 2 of Mediator of RNA polymerase II transcription subunit 16, Isoform 2 of Mediator of RNA polymerase II transcription subunit 8, Mediator of RNA polymerase II transcription subunit 1, ... | 著者 | Yin, X, Li, J, Wu, Z, Liu, W, Xu, Y. | 登録日 | 2021-04-13 | 公開日 | 2021-05-05 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structures of the human Mediator and Mediator-bound preinitiation complex. Science, 372, 2021
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7LUF
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![BU of 7luf by Molmil](/molmil-images/mine/7luf) | HSV1 polymerase ternary complex with dsDNA and PNU-183792 | 分子名称: | DNA (5'-D(*CP*GP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*TP*AP*C)-3'), DNA (5'-D(P*AP*TP*GP*GP*TP*AP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*CP*G)-3'), DNA polymerase, ... | 著者 | Hayes, R.P, Klein, D. | 登録日 | 2021-02-22 | 公開日 | 2021-04-07 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structural understanding of non-nucleoside inhibition in an elongating herpesvirus polymerase. Nat Commun, 12, 2021
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8OJ6
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![BU of 8oj6 by Molmil](/molmil-images/mine/8oj6) | HSV-1 DNA polymerase-processivity factor complex in pre-translocation state | 分子名称: | DNA (22-MER), DNA (48-MER), DNA polymerase catalytic subunit, ... | 著者 | Gustavsson, E, Grunewald, K, Elias, P, Hallberg, B.M. | 登録日 | 2023-03-24 | 公開日 | 2024-04-03 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.41 Å) | 主引用文献 | Dynamics of the Herpes simplex virus DNA polymerase holoenzyme during DNA synthesis and proof-reading revealed by Cryo-EM. Nucleic Acids Res., 52, 2024
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