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8PPT
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BU of 8ppt by Molmil
Pyrococcus abyssi DNA polymerase D (PolD) in its editing mode bound to a primer/template substrate containing a mismatch
分子名称: DNA (5'-D(P*AP*GP*CP*AP*CP*GP*GP*CP*TP*CP*GP*GP*CP*CP*CP*GP*G)-3'), DNA (5'-D(P*CP*CP*GP*GP*GP*CP*CP*GP*AP*GP*CP*CP*GP*TP*GP*CP*TP*TP*T)-3'), DNA polymerase II small subunit, ...
著者Betancurt-Anzola, L, Martinez-Carranza, M, Zatopek, K.M, Gardner, A.F, Sauguet, L.
登録日2023-07-10
公開日2023-12-20
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Molecular basis for proofreading by the unique exonuclease domain of Family-D DNA polymerases.
Nat Commun, 14, 2023
8PSN
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BU of 8psn by Molmil
Tilapia Lake Virus polymerase in vRNA initiation state (transcriptase conformation)
分子名称: 5' vRNA end - vRNA loop (40-mer), DNA (5'-D(*(CTP))-3'), MAGNESIUM ION, ...
著者Arragain, B, Cusack, S.
登録日2023-07-13
公開日2023-12-27
実験手法ELECTRON MICROSCOPY (2.73 Å)
主引用文献Structural and functional analysis of the minimal orthomyxovirus-like polymerase of Tilapia Lake Virus from the highly diverged Amnoonviridae family.
Nat Commun, 14, 2023
8PTJ
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BU of 8ptj by Molmil
Tilapia Lake Virus polymerase in vRNA pre-initiation state mode B (close core | partial replicase conformation)
分子名称: 3' vRNA end - vRNA loop (40-mer), Polymerase acidic protein (PA-like), Putative PB1, ...
著者Arragain, B, Cusack, S.
登録日2023-07-14
公開日2023-12-27
実験手法ELECTRON MICROSCOPY (2.86 Å)
主引用文献Structural and functional analysis of the minimal orthomyxovirus-like polymerase of Tilapia Lake Virus from the highly diverged Amnoonviridae family.
Nat Commun, 14, 2023
8PSO
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BU of 8pso by Molmil
Tilapia Lake Virus polymerase in vRNA initiation state (core only)
分子名称: 5' vRNA end - vRNA loop (40-mer), DNA (5'-D(*(CTP))-3'), MAGNESIUM ION, ...
著者Arragain, B, Cusack, S.
登録日2023-07-13
公開日2023-12-27
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Structural and functional analysis of the minimal orthomyxovirus-like polymerase of Tilapia Lake Virus from the highly diverged Amnoonviridae family.
Nat Commun, 14, 2023
8PSS
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BU of 8pss by Molmil
Tilapia Lake Virus polymerase in cRNA pre-initiation state mode B (core-endo only)
分子名称: 5' cRNA end - cRNA loop (40-mer), MAGNESIUM ION, Polymerase acidic protein (PA-like), ...
著者Arragain, B, Cusack, S.
登録日2023-07-13
公開日2023-12-27
実験手法ELECTRON MICROSCOPY (2.83 Å)
主引用文献Structural and functional analysis of the minimal orthomyxovirus-like polymerase of Tilapia Lake Virus from the highly diverged Amnoonviridae family.
Nat Commun, 14, 2023
8PT2
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BU of 8pt2 by Molmil
Tilapia Lake Virus polymerase in vRNA pre-initiation state mode B (transcriptase conformation)
分子名称: 5' vRNA end - vRNA loop (40-mer), Polymerase acidic protein (PA-like), Putative PB1, ...
著者Arragain, B, Cusack, S.
登録日2023-07-13
公開日2023-12-27
実験手法ELECTRON MICROSCOPY (2.59 Å)
主引用文献Structural and functional analysis of the minimal orthomyxovirus-like polymerase of Tilapia Lake Virus from the highly diverged Amnoonviridae family.
Nat Commun, 14, 2023
8PT7
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BU of 8pt7 by Molmil
Tilapia Lake Virus polymerase in cRNA pre-initiation state mode A (core-endo only)
分子名称: 5'/3' cRNA ends - cRNA loop (40-mer), MAGNESIUM ION, Polymerase acidic protein (PA-like), ...
著者Arragain, B, Cusack, S.
登録日2023-07-13
公開日2023-12-27
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural and functional analysis of the minimal orthomyxovirus-like polymerase of Tilapia Lake Virus from the highly diverged Amnoonviridae family.
Nat Commun, 14, 2023
8PSU
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BU of 8psu by Molmil
Tilapia Lake Virus polymerase in vRNA pre-initiation state mode A (core only)
分子名称: 5' vRNA end - vRNA loop (40-mer), Polymerase acidic protein (PA-like), Putative PB1, ...
著者Arragain, B, Cusack, S.
登録日2023-07-13
公開日2023-12-27
実験手法ELECTRON MICROSCOPY (3.18 Å)
主引用文献Structural and functional analysis of the minimal orthomyxovirus-like polymerase of Tilapia Lake Virus from the highly diverged Amnoonviridae family.
Nat Commun, 14, 2023
8PTH
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BU of 8pth by Molmil
Tilapia Lake Virus polymerase in vRNA pre-initiation state mode B (open core | partial replicase conformation)
分子名称: 3' vRNA end - vRNA loop (40-mer), Polymerase acidic protein (PA-like), Putative PB1, ...
著者Arragain, B, Cusack, S.
登録日2023-07-14
公開日2023-12-27
実験手法ELECTRON MICROSCOPY (2.73 Å)
主引用文献Structural and functional analysis of the minimal orthomyxovirus-like polymerase of Tilapia Lake Virus from the highly diverged Amnoonviridae family.
Nat Commun, 14, 2023
8Q5B
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BU of 8q5b by Molmil
Characterization of the zinc finger u-protein HVO_0758 from Haloferax volcanii: biological roles, zinc binding, and NMR solution structure
分子名称: Small CPxCG-related zinc finger protein
著者Pyper, D.J, Schwalbe, H.
登録日2023-08-08
公開日2023-12-27
実験手法SOLUTION NMR
主引用文献Characterization of the zinc finger mu-protein HVO_0758 from Haloferax volcanii : biological roles, zinc binding, and NMR solution structure.
Front Microbiol, 14, 2023
8PSQ
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BU of 8psq by Molmil
Tilapia Lake Virus polymerase in cRNA pre-initiation state mode A (core only)
分子名称: 5' cRNA end - cRNA loop (40-mer), MAGNESIUM ION, Polymerase acidic protein (PA-like), ...
著者Arragain, B, Cusack, S.
登録日2023-07-13
公開日2023-12-27
実験手法ELECTRON MICROSCOPY (2.65 Å)
主引用文献Structural and functional analysis of the minimal orthomyxovirus-like polymerase of Tilapia Lake Virus from the highly diverged Amnoonviridae family.
Nat Commun, 14, 2023
8PSX
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BU of 8psx by Molmil
Tilapia Lake Virus polymerase in vRNA elongation state (transcriptase conformation)
分子名称: 5' vRNA end - vRNA loop (40-mer), MAGNESIUM ION, Polymerase acidic protein (PA-like), ...
著者Arragain, B, Cusack, S.
登録日2023-07-13
公開日2023-12-27
実験手法ELECTRON MICROSCOPY (2.96 Å)
主引用文献Structural and functional analysis of the minimal orthomyxovirus-like polymerase of Tilapia Lake Virus from the highly diverged Amnoonviridae family.
Nat Commun, 14, 2023
8PT6
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BU of 8pt6 by Molmil
Tilapia Lake Virus polymerase in vRNA initiation state (replicase conformation)
分子名称: 5' vRNA end - vRNA loop (40-mer), DNA (5'-D(*(CTP))-3'), MAGNESIUM ION, ...
著者Arragain, B, Cusack, S.
登録日2023-07-13
公開日2023-12-27
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.03 Å)
主引用文献Structural and functional analysis of the minimal orthomyxovirus-like polymerase of Tilapia Lake Virus from the highly diverged Amnoonviridae family.
Nat Commun, 14, 2023
8PSZ
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BU of 8psz by Molmil
Tilapia Lake Virus polymerase in vRNA elongation state with additional mode B promoter (transcriptase conformation)
分子名称: 5' vRNA end - vRNA loop (40-mer), MAGNESIUM ION, Polymerase acidic protein (PA-like), ...
著者Arragain, B, Cusack, S.
登録日2023-07-13
公開日2024-01-10
実験手法ELECTRON MICROSCOPY (2.42 Å)
主引用文献Structural and functional analysis of the minimal orthomyxovirus-like polymerase of Tilapia Lake Virus from the highly diverged Amnoonviridae family.
Nat Commun, 14, 2023
8PEI
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BU of 8pei by Molmil
Crystal structure of the biphotochromic fluorescent protein SAASoti (C21N/V127T variant) in its green on-state
分子名称: C21N/V127T form of the biphotochromic fluorescent protein SAASoti
著者Boyko, K.M, Varfolomeeva, L.A, Matyuta, I.O, Gavshina, A.V, Solovyev, I.D, Popov, V.O, Savitsky, A.P.
登録日2023-06-14
公開日2024-01-17
最終更新日2024-07-31
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The role of the correlated motion(s) of the chromophore in photoswitching of green and red forms of the photoconvertible fluorescent protein mSAASoti.
Sci Rep, 14, 2024
8PD6
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BU of 8pd6 by Molmil
Crystal structure of the TRIM58 PRY-SPRY domain in complex with TRIM-473
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, E3 ubiquitin-protein ligase TRIM58, ...
著者Renatus, M, Hoegenauer, K, Schroeder, M.
登録日2023-06-11
公開日2024-01-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Discovery of Ligands for TRIM58, a Novel Tissue-Selective E3 Ligase.
Acs Med.Chem.Lett., 14, 2023
8PD4
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BU of 8pd4 by Molmil
Crystal structure of TRIM58 PRY-SPRY domain
分子名称: E3 ubiquitin-protein ligase TRIM58
著者Renatus, M, Schroeder, M.
登録日2023-06-11
公開日2024-01-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.714 Å)
主引用文献Discovery of Ligands for TRIM58, a Novel Tissue-Selective E3 Ligase.
Acs Med.Chem.Lett., 14, 2023
8PHE
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BU of 8phe by Molmil
ACAD9-WT in complex with ECSIT-CTER
分子名称: Complex I assembly factor ACAD9, mitochondrial, Evolutionarily conserved signaling intermediate in Toll pathway
著者McGregor, L, Acajjaoui, S, Desfosses, A, Saidi, M, Bacia-Verloop, M, Schwarz, J.J, Juyoux, P, Von Velsen, J, Bowler, M.W, McCarthy, A, Kandiah, E, Gutsche, I, Soler-Lopez, M.
登録日2023-06-19
公開日2024-01-24
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献The assembly of the Mitochondrial Complex I Assembly complex uncovers a redox pathway coordination.
Nat Commun, 14, 2023
8PHF
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BU of 8phf by Molmil
Cryo-EM structure of human ACAD9-S191A
分子名称: Complex I assembly factor ACAD9, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE
著者McGregor, L, Acajjaoui, S, Desfosses, A, Saidi, M, Bacia-Verloop, M, Schwarz, J.J, Juyoux, P, Von Velsen, J, Bowler, M.W, McCarthy, A, Kandiah, E, Gutsche, I, Soler-Lopez, M.
登録日2023-06-19
公開日2024-01-24
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献The assembly of the Mitochondrial Complex I Assembly complex uncovers a redox pathway coordination.
Nat Commun, 14, 2023
8PDD
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BU of 8pdd by Molmil
Thioredoxin glutathione reductase of Schistosoma mansoni at 1.25A resolution.
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, MAGNESIUM ION, ...
著者Ribeiro, L, Montoya, B.O, Moreira-Filho, J.T, Bowyer, S, Verma, A, Neves, B.J, Owens, R.J, Andrade, C.H, Silva-Jr, F.P, Furnham, N.
登録日2023-06-12
公開日2024-01-31
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Fragment library screening by X-ray crystallography and binding site analysis on thioredoxin glutathione reductase of Schistosoma mansoni.
Sci Rep, 14, 2024
8PL7
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BU of 8pl7 by Molmil
Thioredoxin glutathione reductase of Schistosoma mansoni fragment screen hit 8.
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Thioredoxin glutathione reductase, ~{N}-morpholin-4-ylcarbothioylfuran-2-carboxamide
著者Ribeiro, L, Montoya, B.O, Moreira-Filho, J.T, Bowyer, S, Verma, A, Neves, B.J, Owens, R.J, Andrade, C.H, Silva-Jr, F.P, Furnham, N.
登録日2023-06-27
公開日2024-01-31
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Fragment library screening by X-ray crystallography and binding site analysis on thioredoxin glutathione reductase of Schistosoma mansoni.
Sci Rep, 14, 2024
8PLM
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BU of 8plm by Molmil
Thioredoxin glutathione reductase of Schistosoma mansoni fragment screen hit 23.
分子名称: 1-{4-[(2-methoxyethyl)amino]piperidin-1-yl}ethan-1-one, FLAVIN-ADENINE DINUCLEOTIDE, Thioredoxin glutathione reductase
著者Ribeiro, L, Montoya, B.O, Moreira-Filho, J.T, Bowyer, S, Verma, A, Neves, B.J, Owens, R.J, Andrade, C.H, Silva-Jr, F.P, Furnham, N.
登録日2023-06-27
公開日2024-01-31
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Fragment library screening by X-ray crystallography and binding site analysis on thioredoxin glutathione reductase of Schistosoma mansoni.
Sci Rep, 14, 2024
7TP3
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BU of 7tp3 by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody K288.2
分子名称: CACODYLATE ION, K288.2 heavy chain, K288.2 light chain, ...
著者Yuan, M, Zhu, X, Wilson, I.A.
登録日2022-01-24
公開日2022-02-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques.
Sci Transl Med, 14, 2022
8PLX
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BU of 8plx by Molmil
Thioredoxin glutathione reductase of Schistosoma mansoni fragment screen hit 34.
分子名称: 4-(4-fluorophenyl)piperazine-1-carboxamide, FLAVIN-ADENINE DINUCLEOTIDE, Thioredoxin glutathione reductase
著者Ribeiro, L, Montoya, B.O, Moreira-Filho, J.T, Bowyer, S, Verma, A, Neves, B.J, Owens, R.J, Andrade, C.H, Silva-Jr, F.P, Furnham, N.
登録日2023-06-27
公開日2024-01-31
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Fragment library screening by X-ray crystallography and binding site analysis on thioredoxin glutathione reductase of Schistosoma mansoni.
Sci Rep, 14, 2024
7TP4
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BU of 7tp4 by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody K398.22
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, K398.22 heavy chain, ...
著者Yuan, M, Zhu, X, Wilson, I.A.
登録日2022-01-24
公開日2022-02-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques.
Sci Transl Med, 14, 2022

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件を2024-09-11に公開中

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