PDB: 46006 件ウェブページステータス検索Chemie searchBIRD

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7R44	Bovine complex I in the presence of IM1761092, active class iv (Composite map) 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... 著者 Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. 登録日 2022-02-08 公開日 2023-02-08 実験手法 ELECTRON MICROSCOPY (2.4 Å) 主引用文献 Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
7R4D	Bovine complex I in the presence of IM1761092, deactive class vi (Composite map) 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... 著者 Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. 登録日 2022-02-08 公開日 2023-02-08 実験手法 ELECTRON MICROSCOPY (2.3 Å) 主引用文献 Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
7R41	Bovine complex I in the presence of IM1761092, active class i (Composite map) 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... 著者 Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. 登録日 2022-02-08 公開日 2023-02-08 実験手法 ELECTRON MICROSCOPY (2.3 Å) 主引用文献 Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
7R45	Bovine complex I in the presence of IM1761092, deactive class i (Composite map) 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... 著者 Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. 登録日 2022-02-08 公開日 2023-02-08 実験手法 ELECTRON MICROSCOPY (2.4 Å) 主引用文献 Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
7R46	Bovine complex I in the presence of IM1761092, deactive class ii (Composite map) 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... 著者 Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. 登録日 2022-02-08 公開日 2023-02-08 実験手法 ELECTRON MICROSCOPY (2.4 Å) 主引用文献 Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
4YCE	Crystal structure of the R111K:Y134F:T54V:R132Q:P39Q:R59Y mutant of human cellular retinoic acid binding proteinii with retinal at 1.95 angstrom- visible light irradiated crystal for 1 hour - 2nd cycle 分子名称: Cellular retinoic acid-binding protein 2, RETINAL 著者 Nosrati, M, Geiger, J.H. 登録日 2015-02-19 公開日 2016-02-24 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.953 Å) 主引用文献 A Photoisomerizing Rhodopsin Mimic Observed at Atomic Resolution. J.Am.Chem.Soc., 138, 2016
7R43	Bovine complex I in the presence of IM1761092, active class iii (Composite map) 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... 著者 Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. 登録日 2022-02-08 公開日 2023-02-08 実験手法 ELECTRON MICROSCOPY (2.4 Å) 主引用文献 Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
7R48	Bovine complex I in the presence of IM1761092, deactive class iv (Composite map) 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... 著者 Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. 登録日 2022-02-08 公開日 2023-02-08 実験手法 ELECTRON MICROSCOPY (2.3 Å) 主引用文献 Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
7R47	Bovine complex I in the presence of IM1761092, deactive class iii (Composite map) 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... 著者 Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. 登録日 2022-02-08 公開日 2023-02-08 実験手法 ELECTRON MICROSCOPY (2.3 Å) 主引用文献 Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
4YFR	Crystal structure of the R111K:Y134F:T54V:R132Q:P39Y:R59Y mutant of human Cellular Retinoic Acid Binding Protein II with Retinal at 1.95 Angstrom Resolution - UV irradiated crystal for 30 minutes - 1st Cycle 分子名称: Cellular retinoic acid-binding protein 2, RETINAL 著者 Nosrati, M, Geiger, J.H. 登録日 2015-02-25 公開日 2016-03-02 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.952 Å) 主引用文献 A Photoisomerizing Rhodopsin Mimic Observed at Atomic Resolution. J.Am.Chem.Soc., 138, 2016
5KJ2	The novel p300/CBP inhibitor A-485 uncovers a unique mechanism of action to target AR in castrate resistant prostate cancer 分子名称: Histone acetyltransferase p300, N-[(4-fluorophenyl)methyl]-2-{(1R)-5-[(methylcarbamoyl)amino]-2',4'-dioxo-2,3-dihydro-3'H-spiro[indene-1,5'-[1,3]oxazolidin]-3'-yl}-N-[(2S)-1,1,1-trifluoropropan-2-yl]acetamide, SODIUM ION 著者 Jakob, C.G, Qiu, W, Edalji, R.P, Sun, C. 登録日 2016-06-17 公開日 2017-09-27 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours. Nature, 550, 2017
7R4C	Bovine complex I in the presence of IM1761092, deactive class v (Composite map) 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... 著者 Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. 登録日 2022-02-08 公開日 2023-02-08 実験手法 ELECTRON MICROSCOPY (2.3 Å) 主引用文献 Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
7R4F	Bovine complex I in the presence of IM1761092, slack class i (Composite map) 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... 著者 Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. 登録日 2022-02-08 公開日 2023-02-08 実験手法 ELECTRON MICROSCOPY (2.4 Å) 主引用文献 Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
7R4G	Bovine complex I in the presence of IM1761092, slack class ii (Composite map) 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... 著者 Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. 登録日 2022-02-08 公開日 2023-02-08 実験手法 ELECTRON MICROSCOPY (2.5 Å) 主引用文献 Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
4YKM	Crystal structure of the R111K:Y134F:T54V:R132Q:P39Q:R59Y:A32W:F3Q mutant of human Cellular Retinoic Acid Binding Protein II with Retinal at 1.58 angstrom resolution 分子名称: Cellular retinoic acid-binding protein 2, RETINAL 著者 Nosrati, M, Geiger, J.H. 登録日 2015-03-04 公開日 2016-03-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 A Photoisomerizing Rhodopsin Mimic Observed at Atomic Resolution. J.Am.Chem.Soc., 138, 2016
4YTL	Structure of the KOW2-KOW3 Domain of Transcription Elongation Factor Spt5. 分子名称: GLYCEROL, SULFATE ION, Transcription elongation factor SPT5 著者 Meyer, P.A, Li, S, ZHang, M, Yamada, K, Takagi, Y, Hartzog, G.A, Fu, J. 登録日 2015-03-17 公開日 2015-08-12 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (1.601 Å) 主引用文献 Structures and Functions of the Multiple KOW Domains of Transcription Elongation Factor Spt5. Mol.Cell.Biol., 35, 2015
5KMC	Human Histidine Triad Nucleotide Binding Protein 1 (hHint1) non-nucleotidic covalent intermediate complex 分子名称: Histidine triad nucleotide-binding protein 1, [2-(1~{H}-indol-3-yl)ethylamino]phosphonic acid 著者 Maize, K.M, Finzel, B.C. 登録日 2016-06-26 公開日 2017-06-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Structural Biology for Drug Design: Applications in Two Systems THESIS, University of Minnesota Digital Conservancy, 2016
5KM4	Human Histidine Triad Nucleotide Binding Protein 1 (hHint1)-5-Iodo-UMP complex 分子名称: 5-IODOURIDINE-5'-MONOPHOSPHATE, Histidine triad nucleotide-binding protein 1 著者 Maize, K.M, Finzel, B.C. 登録日 2016-06-26 公開日 2017-06-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 A Crystal Structure Based Guide to the Design of Human Histidine Triad Nucleotide Binding Protein 1 (hHint1) Activated ProTides. Mol. Pharm., 14, 2017
5KLZ	Human Histidine Triad Nucleotide Binding Protein 1 (hHint1) AMP catalytic product complex 分子名称: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, Histidine triad nucleotide-binding protein 1 著者 Maize, K.M, Finzel, B.C. 登録日 2016-06-26 公開日 2017-06-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 A Crystal Structure Based Guide to the Design of Human Histidine Triad Nucleotide Binding Protein 1 (hHint1) Activated ProTides. Mol. Pharm., 14, 2017
4YBP	Crystal structure of the R111K:Y134F:T54V:R132Q:P39Q:R59Y mutant of human cellular retinoic acid binding proteinii with retinal after 24 hour incubation at 1.83 angstrom resolution - thermodynamic product - 1st cycle 分子名称: Cellular retinoic acid-binding protein 2, RETINAL 著者 Nosrati, M, Geiger, J.H. 登録日 2015-02-19 公開日 2016-02-24 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.831 Å) 主引用文献 A Photoisomerizing Rhodopsin Mimic Observed at Atomic Resolution. J.Am.Chem.Soc., 138, 2016
4YKO	Crystal structure of the R111K:Y134F:T54V:R132Q:P39Q:R59Y:A32Y:F3Q mutant of human Cellular Retinoic Acid Binding Protein II with Retinal at 1.58 angstrom resolution 分子名称: Cellular retinoic acid-binding protein 2, RETINAL 著者 Nosrati, M, Geiger, J. 登録日 2015-03-04 公開日 2016-03-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 A Photoisomerizing Rhodopsin Mimic Observed at Atomic Resolution. J.Am.Chem.Soc., 138, 2016
4YGZ	CRYSTAL STRUCTURE OF THE R111K:Y134F:T54V:R132Q:P39Y:R59Y MUTANT OF HUMAN CELLULAR RETINOIC ACID BINDING PROTEIN II WITH RETINAL AT 2.06 ANGSTROM RESOLUTION - VISIBLE LIGHT IRRADIATED CRYSTAL -3RD CYCLE 分子名称: Cellular retinoic acid-binding protein 2, RETINAL 著者 Nosrati, M, Geiger, J.H. 登録日 2015-02-26 公開日 2016-03-02 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 A Photoisomerizing Rhodopsin Mimic Observed at Atomic Resolution. J.Am.Chem.Soc., 138, 2016
5J9K	Crystal structure of the rice Topless related protein 2 (TPR2) N-terminal topless domain (1-209) in complex with rice D53 repressor EAR peptide motif 分子名称: Protein TPR1, ZINC ION, rice D53 peptide 794-808 著者 Ke, J, Ma, H, Gu, X, Brunzelle, J.S, Xu, H.E, Melcher, K. 登録日 2016-04-10 公開日 2017-07-05 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 A D53 repression motif induces oligomerization of TOPLESS corepressors and promotes assembly of a corepressor-nucleosome complex. Sci Adv, 3, 2017
4YK0	Crystal structure of the CBP bromodomain in complex with CPI098 分子名称: (4R)-4-methyl-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one, 1,2-ETHANEDIOL, CREB-binding protein 著者 Bellon, S.F, Jayaram, H. 登録日 2015-03-03 公開日 2016-04-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Regulatory T Cell Modulation by CBP/EP300 Bromodomain Inhibition. J.Biol.Chem., 291, 2016
4Y3I	PAS-GAF fragment from Deinococcus radiodurans BphP assembled with BV - Y307S, low dose 分子名称: 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium-2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, Bacteriophytochrome 著者 Li, F, Burgie, E.S, Yu, T, Heroux, A, Schatz, G.C, Vierstra, R.D, Orville, A.M. 登録日 2015-02-10 公開日 2015-05-20 最終更新日 2019-11-27 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 X-ray radiation induces deprotonation of the bilin chromophore in crystalline D. radiodurans phytochrome. J.Am.Chem.Soc., 137, 2015

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