7VYQ
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![BU of 7vyq by Molmil](/molmil-images/mine/7vyq) | Short chain dehydrogenase (SCR) cryoEM structure with NADP and ethyl 4-chloroacetoacetate | 分子名称: | Carbonyl Reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ethyl 4-chloranyl-3-oxidanylidene-butanoate | 著者 | Li, Y.H, Zhang, R.Z, Wang, C, Forouhar, F, Clarke, O, Vorobiev, S, Singh, S, Montelione, G.T, Szyperski, T, Xu, Y, Hunt, J.F. | 登録日 | 2021-11-15 | 公開日 | 2022-04-06 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | 主引用文献 | Oligomeric interactions maintain active-site structure in a noncooperative enzyme family. Embo J., 41, 2022
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3FWJ
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![BU of 3fwj by Molmil](/molmil-images/mine/3fwj) | Ferric camphor bound Cytochrome P450cam containing a selenocysteine as the 5th heme ligand, orthorombic crystal form | 分子名称: | CAMPHOR, Camphor 5-monooxygenase, POTASSIUM ION, ... | 著者 | Schlichting, I, von Koenig, K, Aldag, C, Hilvert, D. | 登録日 | 2009-01-18 | 公開日 | 2009-03-03 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Probing the role of the proximal heme ligand in cytochrome P450cam by recombinant incorporation of selenocysteine. Proc.Natl.Acad.Sci.USA, 106, 2009
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6G0L
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![BU of 6g0l by Molmil](/molmil-images/mine/6g0l) | Structure of two molecules of the chromatin remodelling enzyme Chd1 bound to a nucleosome | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromo domain-containing protein 1, ... | 著者 | Sundaramoorthy, R, Owen-hughes, T, Norman, D.G, Hughes, A. | 登録日 | 2018-03-19 | 公開日 | 2018-08-22 | 最終更新日 | 2018-11-21 | 実験手法 | ELECTRON MICROSCOPY (10 Å) | 主引用文献 | Structure of the chromatin remodelling enzyme Chd1 bound to a ubiquitinylated nucleosome. Elife, 7, 2018
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5ZNT
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![BU of 5znt by Molmil](/molmil-images/mine/5znt) | Insect chitin deacetylase | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ZINC ION, ... | 著者 | Liu, L, Zhou, Y, Yang, Q. | 登録日 | 2018-04-10 | 公開日 | 2019-02-20 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.979 Å) | 主引用文献 | Structural and biochemical insights into the catalytic mechanisms of two insect chitin deacetylases of the carbohydrate esterase 4 family. J. Biol. Chem., 294, 2019
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6GBL
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![BU of 6gbl by Molmil](/molmil-images/mine/6gbl) | Repertoires of functionally diverse enzymes through computational design at epistatic active-site positions | 分子名称: | 1,2-ETHANEDIOL, CACODYLATE ION, FORMIC ACID, ... | 著者 | Khersonsky, O, Lipsh, R, Avizemer, Z, Goldsmith, M, Ashani, Y, Leader, H, Dym, O, Rogotner, S, Trudeau, D, Tawfik, D.S, Fleishman, S.J. | 登録日 | 2018-04-15 | 公開日 | 2018-10-24 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Automated Design of Efficient and Functionally Diverse Enzyme Repertoires. Mol. Cell, 72, 2018
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7VBL
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![BU of 7vbl by Molmil](/molmil-images/mine/7vbl) | Membrane arm of active state CI from DQ-NADH dataset | 分子名称: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Gu, J.K, Yang, M.J. | 登録日 | 2021-08-31 | 公開日 | 2022-04-06 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | The coupling mechanism of mammalian mitochondrial complex I. Nat.Struct.Mol.Biol., 29, 2022
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4TPN
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![BU of 4tpn by Molmil](/molmil-images/mine/4tpn) | High-resolution structure of TxtE in the absence of substrate | 分子名称: | GLYCEROL, LITHIUM ION, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Cahn, J.K.B, Dodani, S.C, Brinkmann-Chen, S, Heinsich, T, McIntosh, J.A, Arnold, F.H. | 登録日 | 2014-06-08 | 公開日 | 2014-09-10 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.18 Å) | 主引用文献 | Structural, Functional, and Spectroscopic Characterization of the Substrate Scope of the Novel Nitrating Cytochrome P450 TxtE. Chembiochem, 15, 2014
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2TAA
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![BU of 2taa by Molmil](/molmil-images/mine/2taa) | STRUCTURE AND POSSIBLE CATALYTIC RESIDUES OF TAKA-AMYLASE A | 分子名称: | CALCIUM ION, TAKA-AMYLASE A | 著者 | Kusunoki, M, Matsuura, Y, Tanaka, N, Kakudo, M. | 登録日 | 1982-10-18 | 公開日 | 1982-10-21 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure and possible catalytic residues of Taka-amylase A J.Biochem.(Tokyo), 95, 1984
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6K9D
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![BU of 6k9d by Molmil](/molmil-images/mine/6k9d) | glycoside hydrolase family 12 (GH12) englucanase | 分子名称: | GH12 beta-1, 4-endoglucanase | 著者 | Hong, Y, Tao, T, Pengjun, S, Jiaming, C, Xiaoyu, W, Chen, H, Yingguo, B, Bin, Y. | 登録日 | 2019-06-14 | 公開日 | 2020-06-17 | 実験手法 | X-RAY DIFFRACTION (1.505 Å) | 主引用文献 | Substrates promiscuity of xyloglucanases and endoglucanases of glycoside hydrolase 12 family To Be Published
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6B0D
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![BU of 6b0d by Molmil](/molmil-images/mine/6b0d) | An E. coli DPS protein from ferritin superfamily | 分子名称: | DNA protection during starvation protein, FORMIC ACID, SODIUM ION | 著者 | Rui, W, Ruslan, S, Ronan, K, Adam, J.S. | 登録日 | 2017-09-14 | 公開日 | 2018-09-19 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | SIMBAD: a sequence-independent molecular-replacement pipeline. Acta Crystallogr D Struct Biol, 74, 2018
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4TQT
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3GED
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![BU of 3ged by Molmil](/molmil-images/mine/3ged) | Fingerprint and Structural Analysis of a Apo SCOR enzyme from Clostridium thermocellum | 分子名称: | GLYCEROL, SODIUM ION, Short-chain dehydrogenase/reductase SDR, ... | 著者 | Huether, R, Liu, Z.J, Xu, H, Wang, B.C, Pletnev, V, Mao, Q, Umland, T, Duax, W. | 登録日 | 2009-02-25 | 公開日 | 2009-03-17 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.698 Å) | 主引用文献 | Sequence fingerprint and structural analysis of the SCOR enzyme A3DFK9 from Clostridium thermocellum. Proteins, 78, 2010
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6B0Z
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![BU of 6b0z by Molmil](/molmil-images/mine/6b0z) | IDH1 R132H mutant in complex with IDH305 | 分子名称: | (4R)-4-[(1S)-1-fluoroethyl]-3-[2-({(1S)-1-[4-methyl-2'-(trifluoromethyl)[3,4'-bipyridin]-6-yl]ethyl}amino)pyrimidin-4-yl]-1,3-oxazolidin-2-one, CITRATE ANION, Isocitrate dehydrogenase [NADP] cytoplasmic, ... | 著者 | Xie, X, Kulathila, R. | 登録日 | 2017-09-15 | 公開日 | 2017-11-08 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.334 Å) | 主引用文献 | Discovery and Evaluation of Clinical Candidate IDH305, a Brain Penetrant Mutant IDH1 Inhibitor. ACS Med Chem Lett, 8, 2017
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3HH6
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![BU of 3hh6 by Molmil](/molmil-images/mine/3hh6) | New azaborine compounds bind to the T4 lysozyme L99A cavity -ethylbenzene as control | 分子名称: | 2-HYDROXYETHYL DISULFIDE, Lysozyme, PHENYLETHANE, ... | 著者 | Liu, L, Matthews, B.W. | 登録日 | 2009-05-14 | 公開日 | 2009-10-13 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Boron mimetics: 1,2-dihydro-1,2-azaborines bind inside a nonpolar cavity of T4 lysozyme. Angew.Chem.Int.Ed.Engl., 48, 2009
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5YUQ
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![BU of 5yuq by Molmil](/molmil-images/mine/5yuq) | The high resolution structure of chitinase (RmChi1) from the thermophilic fungus Rhizomucor miehei (sp P1) | 分子名称: | Chintase | 著者 | Jiang, Z.Q, Hu, S.Q, Liu, Y.C, Qin, Z, Yan, Q.J, Yang, S.Q. | 登録日 | 2017-11-23 | 公開日 | 2018-11-28 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | 主引用文献 | Crystal structure of a chitinase (RmChiA) from the thermophilic fungus Rhizomucor miehei with a real active site tunnel. Biochim Biophys Acta Proteins Proteom, 2021
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7VBP
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![BU of 7vbp by Molmil](/molmil-images/mine/7vbp) | Membrane arm of deactive state CI from DQ-NADH dataset | 分子名称: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Gu, J.K, Yang, M.J. | 登録日 | 2021-09-01 | 公開日 | 2022-04-06 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | The coupling mechanism of mammalian mitochondrial complex I. Nat.Struct.Mol.Biol., 29, 2022
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5Z18
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![BU of 5z18 by Molmil](/molmil-images/mine/5z18) | |
3HHG
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![BU of 3hhg by Molmil](/molmil-images/mine/3hhg) | Structure of CrgA, a LysR-type transcriptional regulator from Neisseria meningitidis. | 分子名称: | Transcriptional regulator, LysR family | 著者 | Sainsbury, S, Ren, J, Owens, R.J, Stuart, D.I, Oxford Protein Production Facility (OPPF) | 登録日 | 2009-05-15 | 公開日 | 2009-07-07 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | The structure of CrgA from Neisseria meningitidis reveals a new octameric assembly state for LysR transcriptional regulators Nucleic Acids Res., 37, 2009
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7VWJ
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![BU of 7vwj by Molmil](/molmil-images/mine/7vwj) | Matrix arm of deactive state CI from rotenone-NADH dataset | 分子名称: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... | 著者 | Gu, J.K, Yang, M.J. | 登録日 | 2021-11-10 | 公開日 | 2022-04-06 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | The coupling mechanism of mammalian mitochondrial complex I. Nat.Struct.Mol.Biol., 29, 2022
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6KME
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![BU of 6kme by Molmil](/molmil-images/mine/6kme) | Crystal structure of phytochromobilin synthase from tomato in complex with biliverdin | 分子名称: | BILIVERDINE IX ALPHA, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Sugishima, M, Wada, K, Fukuyama, K. | 登録日 | 2019-07-31 | 公開日 | 2019-12-18 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal structure of phytochromobilin synthase in complex with biliverdin IX alpha , a key enzyme in the biosynthesis of phytochrome. J.Biol.Chem., 295, 2020
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3HKP
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![BU of 3hkp by Molmil](/molmil-images/mine/3hkp) | Crystal structure determination of Catechol 1,2-Dioxygenase from Rhodococcus opacus 1CP in complex with protocatechuate | 分子名称: | (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 3,4-DIHYDROXYBENZOIC ACID, Catechol 1,2-dioxygenase, ... | 著者 | Matera, I, Ferraroni, M, Kolomytseva, M, Briganti, F, Scozzafava, A. | 登録日 | 2009-05-25 | 公開日 | 2010-01-12 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Catechol 1,2-dioxygenase from the Gram-positive Rhodococcus opacus 1CP: Quantitative structure/activity relationship and the crystal structures of native enzyme and catechols adducts. J.Struct.Biol., 170, 2010
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7VBN
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![BU of 7vbn by Molmil](/molmil-images/mine/7vbn) | Matrix arm of deactive state CI from DQ-NADH dataset | 分子名称: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... | 著者 | Gu, J.K, Yang, M.J. | 登録日 | 2021-08-31 | 公開日 | 2022-04-06 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | The coupling mechanism of mammalian mitochondrial complex I. Nat.Struct.Mol.Biol., 29, 2022
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7VWL
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![BU of 7vwl by Molmil](/molmil-images/mine/7vwl) | Membrane arm of deactive state CI from rotenone-NADH dataset | 分子名称: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Gu, J.K, Yang, M.J. | 登録日 | 2021-11-11 | 公開日 | 2022-04-06 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | The coupling mechanism of mammalian mitochondrial complex I. Nat.Struct.Mol.Biol., 29, 2022
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4S2D
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![BU of 4s2d by Molmil](/molmil-images/mine/4s2d) | Joint X-ray/neutron structure of Trichoderma reesei xylanase II in complex with MES at pH 5.7 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Endo-1,4-beta-xylanase 2, IODIDE ION | 著者 | Kovalevsky, A.Y, Wan, Q, Langan, P. | 登録日 | 2015-01-20 | 公開日 | 2015-09-23 | 最終更新日 | 2019-12-25 | 実験手法 | NEUTRON DIFFRACTION (1.6 Å), X-RAY DIFFRACTION | 主引用文献 | Direct determination of protonation states and visualization of hydrogen bonding in a glycoside hydrolase with neutron crystallography. Proc.Natl.Acad.Sci.USA, 112, 2015
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4S2F
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![BU of 4s2f by Molmil](/molmil-images/mine/4s2f) | Joint X-ray/neutron structure of Trichoderma reesei xylanase II at pH 4.4 | 分子名称: | Endo-1,4-beta-xylanase 2, IODIDE ION | 著者 | Kovalevsky, A, Wan, Q, Langan, P. | 登録日 | 2015-01-20 | 公開日 | 2015-09-23 | 最終更新日 | 2019-12-25 | 実験手法 | NEUTRON DIFFRACTION (1.7 Å), X-RAY DIFFRACTION | 主引用文献 | Direct determination of protonation states and visualization of hydrogen bonding in a glycoside hydrolase with neutron crystallography. Proc.Natl.Acad.Sci.USA, 112, 2015
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