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7VYQ

Short chain dehydrogenase (SCR) cryoEM structure with NADP and ethyl 4-chloroacetoacetate

Summary for 7VYQ
Entry DOI10.2210/pdb7vyq/pdb
EMDB information32211
DescriptorCarbonyl Reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ethyl 4-chloranyl-3-oxidanylidene-butanoate (3 entities in total)
Functional Keywordsrossman fold, tetramer, tag-free, wild type with nadph, oxidoreductase
Biological sourceCandida parapsilosis (Yeast)
Total number of polymer chains4
Total formula weight124451.46
Authors
Li, Y.H.,Zhang, R.Z.,Wang, C.,Forouhar, F.,Clarke, O.,Vorobiev, S.,Singh, S.,Montelione, G.T.,Szyperski, T.,Xu, Y.,Hunt, J.F. (deposition date: 2021-11-15, release date: 2022-04-06, Last modification date: 2022-09-14)
Primary citationLi, Y.,Zhang, R.,Wang, C.,Forouhar, F.,Clarke, O.B.,Vorobiev, S.,Singh, S.,Montelione, G.T.,Szyperski, T.,Xu, Y.,Hunt, J.F.
Oligomeric interactions maintain active-site structure in a noncooperative enzyme family.
Embo J., 41:e108368-e108368, 2022
Cited by
PubMed: 35801308
DOI: 10.15252/embj.2021108368
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.13 Å)
Structure validation

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