7QKM
 
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2MBK
 | | The Clip-segment of the von Willebrand domain 1 of the BMP modulator protein Crossveinless 2 is preformed | | 分子名称: | Crossveinless 2 | | 著者 | Mueller, T.D, Fiebig, J.E, Weidauer, S.E, Qiu, L, Bauer, M, Schmieder, P, Beerbaum, M, Zhang, J, Oschkinat, H, Sebald, W. | | 登録日 | 2013-08-02 | | 公開日 | 2013-10-16 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The Clip-Segment of the von Willebrand Domain 1 of the BMP Modulator Protein Crossveinless 2 Is Preformed.
Molecules, 18, 2013
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2XPB
 | | DISCOVERY OF CELL-ACTIVE PHENYL-IMIDAZOLE PIN1 INHIBITORS BY STRUCTURE-GUIDED FRAGMENT EVOLUTION | | 分子名称: | 5-[BENZYL(METHYL)CARBAMOYL]-2-(3-CHLOROPHENYL)-1H-IMIDAZOLE-4-CARBOXYLIC ACID, DODECAETHYLENE GLYCOL, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NIMA-INTERACTING 1 | | 著者 | Potter, A, Oldfield, V, Nunns, C, Fromont, C, Ray, S, Northfield, C.J, Bryant, C.J, Scrace, S.F, Robinson, D, Matossova, N, Baker, L, Dokurno, P, Surgenor, A.E, Davis, B.E, Richardson, C.M, Murray, J.B, Moore, J.D. | | 登録日 | 2010-08-25 | | 公開日 | 2011-01-12 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Discovery of Cell-Active Phenyl-Imidazole Pin1 Inhibitors by Structure-Guided Fragment Evolution.
Bioorg.Med.Chem.Lett., 20, 2010
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7SOL
 | | Crystal Structures of the bispecific ubiquitin/FAT10 activating enzyme, Uba6 | | 分子名称: | ADENOSINE MONOPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, Ubiquitin, ... | | 著者 | Olsen, S.K, Gao, F, Lv, Z. | | 登録日 | 2021-10-31 | | 公開日 | 2022-11-02 | | 最終更新日 | 2024-04-17 | | 実験手法 | X-RAY DIFFRACTION (2.25000644 Å) | | 主引用文献 | Crystal structures reveal catalytic and regulatory mechanisms of the dual-specificity ubiquitin/FAT10 E1 enzyme Uba6.
Nat Commun, 13, 2022
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7QKI
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7ALO
 | | Structure of B*27:09/photoRL9 | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Loll, B, Lan, H, Freund, C. | | 登録日 | 2020-10-07 | | 公開日 | 2021-06-16 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Exchange catalysis by tapasin exploits conserved and allele-specific features of MHC-I molecules.
Nat Commun, 12, 2021
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2MBB
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7QL4
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7ET2
 | | Human Cytomegalovirus, C12 portal | | 分子名称: | Portal protein | | 著者 | Li, Z, Yu, X. | | 登録日 | 2021-05-12 | | 公開日 | 2021-07-14 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structural basis for genome packaging, retention, and ejection in human cytomegalovirus.
Nat Commun, 12, 2021
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2M55
 | | NMR structure of the complex of an N-terminally acetylated alpha-synuclein peptide with calmodulin | | 分子名称: | Alpha-synuclein, CALCIUM ION, Calmodulin | | 著者 | Gruschus, J.M, Yap, T, Pistolesi, S, Maltsev, A.S, Lee, J.C. | | 登録日 | 2013-02-13 | | 公開日 | 2013-05-08 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR Structure of Calmodulin Complexed to an N-Terminally Acetylated alpha-Synuclein Peptide.
Biochemistry, 52, 2013
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7ETM
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2GBC
 | | Native DPP-IV (CD26) from Rat | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Dipeptidyl peptidase 4 | | 著者 | Longenecker, K.L, Jakob, C.G, Fry, E.H, Wilk, S. | | 登録日 | 2006-03-10 | | 公開日 | 2006-07-04 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal Structures of DPP-IV (CD26) from Rat Kidney Exhibit Flexible Accommodation of Peptidase-Selective Inhibitors.
Biochemistry, 45, 2006
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3IJ0
 | | Crystal structure of Eed in complex with a trimethylated histone H3K9 peptide | | 分子名称: | Histone H3K9 peptide, Polycomb protein EED | | 著者 | Justin, N, Sharpe, M.L, Martin, S, Taylor, W.R, De Marco, V, Gamblin, S.J. | | 登録日 | 2009-08-03 | | 公開日 | 2009-09-15 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Role of the polycomb protein EED in the propagation of repressive histone marks.
Nature, 461, 2009
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7QKU
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7EP0
 | | Crystal structure of ZYG11B bound to GSTE degron | | 分子名称: | Protein zyg-11 homolog B, sodium 3,3'-(1E,1'E)-biphenyl-4,4'-diylbis(diazene-2,1-diyl)bis(4-aminonaphthalene-1-sulfonate) | | 著者 | Yan, X, Li, Y. | | 登録日 | 2021-04-26 | | 公開日 | 2021-07-14 | | 最終更新日 | 2021-09-01 | | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | | 主引用文献 | Molecular basis for recognition of Gly/N-degrons by CRL2 ZYG11B and CRL2 ZER1 .
Mol.Cell, 81, 2021
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7QKW
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2MDR
 | | Solution structure of the third double-stranded RNA-binding domain (dsRBD3) of human adenosine-deaminase ADAR1 | | 分子名称: | Double-stranded RNA-specific adenosine deaminase | | 著者 | Barraud, P, Banerjee, S, Mohamed, W.I, Jantsch, M.F, Allain, F.H. | | 登録日 | 2013-09-17 | | 公開日 | 2014-04-30 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A bimodular nuclear localization signal assembled via an extended double-stranded RNA-binding domain acts as an RNA-sensing signal for transportin 1.
Proc.Natl.Acad.Sci.USA, 111, 2014
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7AZW
 | | Crystal structure of the MIZ1-BTB-domain | | 分子名称: | GLYCEROL, Zinc finger and BTB domain-containing protein 17 isoform X1 | | 著者 | Orth, B, Sander, B, Diederichs, K, Lorenz, S. | | 登録日 | 2020-11-17 | | 公開日 | 2021-06-23 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Identification of an atypical interaction site in the BTB domain of the MYC-interacting zinc-finger protein 1.
Structure, 29, 2021
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7KV0
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7QKV
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7QGO
 | | Human CD73 (ecto 5'-nucleotidase) in complex with MRS4602 (a 3-methyl-CMPCP derivative, compound 21 in paper) in the closed state (crystal form III) | | 分子名称: | 5'-nucleotidase, ZINC ION, [[(2~{R},3~{S},4~{R},5~{R})-5-[(4~{E})-4-[(4-methoxycarbonylphenyl)methoxyimino]-3-methyl-2-oxidanylidene-pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]methylphosphonic acid | | 著者 | Strater, N. | | 登録日 | 2021-12-09 | | 公開日 | 2022-02-16 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.206 Å) | | 主引用文献 | Structure-Activity Relationship of 3-Methylcytidine-5'-alpha , beta-methylenediphosphates as CD73 Inhibitors.
J.Med.Chem., 65, 2022
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8PN8
 | | Engineered glycolyl-CoA carboxylase (L100N variant) with bound CoA | | 分子名称: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, COENZYME A, Propionyl-CoA carboxylase alpha subunit, ... | | 著者 | Zarzycki, J, Marchal, D.G, Schulz, L, Prinz, S, Erb, T.J. | | 登録日 | 2023-06-30 | | 公開日 | 2023-11-29 | | 最終更新日 | 2023-12-27 | | 実験手法 | ELECTRON MICROSCOPY (2.31 Å) | | 主引用文献 | Machine Learning-Supported Enzyme Engineering toward Improved CO 2 -Fixation of Glycolyl-CoA Carboxylase.
Acs Synth Biol, 12, 2023
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7QK2
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7STS
 | | Crystal Structure of Human Fab S24-1379 in the Complex with the N-teminal Domain of Nucleocapsid Protein from SARS CoV-2 | | 分子名称: | Fab S24-1379, heavy chain, light chain, ... | | 著者 | Kim, Y, Maltseva, N, Tesar, C, Jedrzejczak, R, Dugan, H, Stamper, C, Wilson, P, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2021-11-15 | | 公開日 | 2022-08-10 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | | 主引用文献 | Epitopes recognition of SARS-CoV-2 nucleocapsid RNA binding domain by human monoclonal antibodies.
Iscience, 27, 2024
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2G6N
 | | Strcture of rat nNOS heme domain (BH2 bound) complexed with CO | | 分子名称: | 7,8-DIHYDROBIOPTERIN, ACETATE ION, ARGININE, ... | | 著者 | Li, H, Igarashi, J, Jamal, J, Yang, W, Poulos, T.L. | | 登録日 | 2006-02-24 | | 公開日 | 2006-08-08 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural studies of constitutive nitric oxide synthases with diatomic ligands bound.
J.Biol.Inorg.Chem., 11, 2006
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