2JJD
 
 | | Protein Tyrosine Phosphatase, Receptor Type, E isoform | | 分子名称: | CHLORIDE ION, RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE EPSILON | | 著者 | Elkins, J.M, Ugochukwu, E, Alfano, I, Barr, A.J, Bunkoczi, G, King, O.N.F, Filippakopoulos, P, Savitsky, P, Salah, E, Pike, A, Johansson, C, Das, S, Burgess-Brown, N.A, Gileadi, O, von Delft, F, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Knapp, S. | | 登録日 | 2008-03-31 | | 公開日 | 2008-04-08 | | 最終更新日 | 2012-06-06 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Large-Scale Structural Analysis of the Classical Human Protein Tyrosine Phosphatome.
Cell(Cambridge,Mass.), 136, 2009
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1P8M
 | | Structural and Functional Importance of First-Shell Metal Ligands in the Binuclear Manganese Cluster of Arginase I. | | 分子名称: | Arginase 1, MANGANESE (II) ION | | 著者 | Cama, E, Emig, F.A, Ash, E.-D, Christianson, D.W. | | 登録日 | 2003-05-07 | | 公開日 | 2003-06-17 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | | 主引用文献 | Structural and functional importance of first-shell metal ligands in the binuclear manganese cluster of arginase I.
Biochemistry, 42, 2003
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1F6I
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1F6J
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1F6D
 | | THE STRUCTURE OF UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE FROM E. COLI. | | 分子名称: | CHLORIDE ION, SODIUM ION, UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE, ... | | 著者 | Campbell, R.E, Mosimann, S.C, Tanner, M.E, Strynadka, N.C.J. | | 登録日 | 2000-06-21 | | 公開日 | 2000-12-13 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The structure of UDP-N-acetylglucosamine 2-epimerase reveals homology to phosphoglycosyl transferases.
Biochemistry, 39, 2000
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2PGQ
 | | Human thrombin mutant C191A-C220A in complex with the inhibitor PPACK | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, Thrombin heavy chain, ... | | 著者 | Bush-Pelc, L.A, Marino, F, Chen, Z, Pineda, A.O, Mathews, F.S, Di Cera, E. | | 登録日 | 2007-04-10 | | 公開日 | 2007-07-17 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Important role of the cys-191 cys-220 disulfide bond in thrombin function and allostery
J.Biol.Chem., 282, 2007
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1FSF
 | | GLUCOSAMINE-6-PHOSPHATE DEAMINASE FROM E.COLI, T CONFORMER, AT 1.9A RESOLUTION | | 分子名称: | GLUCOSAMINE-6-PHOSPHATE DEAMINASE | | 著者 | Rudino-Pinera, E, Morales-Arrieta, S, Rojas-Trejo, S.P, Horjales, E. | | 登録日 | 2000-09-08 | | 公開日 | 2002-01-04 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural flexibility, an essential component of the allosteric activation in Escherichia coli glucosamine-6-phosphate deaminase.
Acta Crystallogr.,Sect.D, 58, 2002
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1F76
 | | ESCHERICHIA COLI DIHYDROOROTATE DEHYDROGENASE | | 分子名称: | Dihydroorotate dehydrogenase (quinone), FLAVIN MONONUCLEOTIDE, FORMIC ACID, ... | | 著者 | Norager, S, Jensen, K.F, Bjornberg, O, Larsen, S. | | 登録日 | 2000-06-26 | | 公開日 | 2002-10-16 | | 最終更新日 | 2014-03-12 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | E. coli Dihydroorotate Dehydrogenase Reveals Structural and Functional Distinction between different classes of
dihydroorotate dehydrogenases
Structure, 10, 2002
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1UMP
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3J6E
 | | Energy minimized average structure of Microtubules stabilized by GmpCpp | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... | | 著者 | Alushin, G.M, Lander, G.C, Kellogg, E.H, Zhang, R, Baker, D, Nogales, E. | | 登録日 | 2014-02-18 | | 公開日 | 2014-06-04 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | | 主引用文献 | High-Resolution Microtubule Structures Reveal the Structural Transitions in alpha beta-Tubulin upon GTP Hydrolysis.
Cell(Cambridge,Mass.), 157, 2014
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3J6F
 | | Minimized average structure of GDP-bound dynamic microtubules | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Alushin, G.M, Lander, G.C, Kellogg, E.H, Zhang, R, Baker, D, Nogales, E. | | 登録日 | 2014-02-19 | | 公開日 | 2014-06-04 | | 最終更新日 | 2018-07-18 | | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | | 主引用文献 | High-Resolution Microtubule Structures Reveal the Structural Transitions in alpha beta-Tubulin upon GTP Hydrolysis.
Cell(Cambridge,Mass.), 157, 2014
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1USL
 | | Structure Of Mycobacterium tuberculosis Ribose-5-Phosphate Isomerase, RpiB, Rv2465c, Complexed With Phosphate. | | 分子名称: | PHOSPHATE ION, RIBOSE 5-PHOSPHATE ISOMERASE B | | 著者 | Roos, A.K, Andersson, C.E, Unge, T, Jones, T.A, Mowbray, S.L. | | 登録日 | 2003-11-25 | | 公開日 | 2004-01-02 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | Mycobacterium Tuberculosis Ribose-5-Phosphate Isomerase Has a Known Fold, But a Novel Active Site
J.Mol.Biol., 335, 2004
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1GES
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3J6G
 | | Minimized average structure of microtubules stabilized by taxol | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Alushin, G.M, Lander, G.C, Kellogg, E.H, Zhang, R, Baker, D, Nogales, E. | | 登録日 | 2014-02-19 | | 公開日 | 2014-06-04 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (5.5 Å) | | 主引用文献 | High-Resolution Microtubule Structures Reveal the Structural Transitions in alpha beta-Tubulin upon GTP Hydrolysis.
Cell(Cambridge,Mass.), 157, 2014
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2PG8
 | | Crystal structure of R254K mutanat of DpgC with bound substrate analog | | 分子名称: | DpgC, OXYGEN MOLECULE, [(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-4-HYDROXY-3-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL (3R)-4-({3-[(2-{[(3,5-DIHYDROXYPHENYL)ACETYL]AMINO}ETHYL)AMINO]-3-OXOPROPYL}AMINO)-3-HYDROXY-2,2-DIMETHYL-4-OXOBUTYL DIHYDROGEN DIPHOSPHATE | | 著者 | Fielding, E.N. | | 登録日 | 2007-04-09 | | 公開日 | 2008-01-22 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Substrate Recognition and Catalysis by the Cofactor-Independent Dioxygenase DpgC.
Biochemistry, 46, 2007
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1C3E
 | | NEW INSIGHTS INTO INHIBITOR DESIGN FROM THE CRYSTAL STRUCTURE AND NMR STUDIES OF E. COLI GAR TRANSFORMYLATE IN COMPLEX WITH BETA-GAR AND 10-FORMYL-5,8,10-TRIDEAZAFOLIC ACID. | | 分子名称: | 2-{4-[2-(2-AMINO-4-HYDROXY-QUINAZOLIN-6-YL)-1-CARBOXY-ETHYL]-BENZOYLAMINO}-PENTANEDIOIC ACID, GLYCINAMIDE RIBONUCLEOTIDE, GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE | | 著者 | Greasley, S.E, Yamashita, M.M, Cai, H, Benkovic, S.J, Boger, D.L, Wilson, I.A. | | 登録日 | 1999-07-27 | | 公開日 | 1999-12-29 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | New insights into inhibitor design from the crystal structure and NMR studies of Escherichia coli GAR transformylase in complex with beta-GAR and 10-formyl-5,8,10-trideazafolic acid.
Biochemistry, 38, 1999
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2PGB
 | | Inhibitor-free human thrombin mutant C191A-C220A | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Prothrombin, SULFATE ION | | 著者 | Bush-Pelc, L.A, Marino, F, Chen, Z, Pineda, A.O, Mathews, F.S, Di Cera, E. | | 登録日 | 2007-04-09 | | 公開日 | 2007-07-17 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | Important role of the cys-191 cys-220 disulfide bond in thrombin function and allostery
J.Biol.Chem., 282, 2007
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1GEU
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2AJH
 | | Crystal structure of the editing domain of E. coli leucyl-tRNA synthetase complexes with methionine | | 分子名称: | Leucyl-tRNA synthetase, METHIONINE | | 著者 | Liu, Y, Liao, J, Zhu, B, Wang, E.D, Ding, J. | | 登録日 | 2005-08-02 | | 公開日 | 2006-01-24 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structures of the editing domain of Escherichia coli leucyl-tRNA synthetase and its complexes with Met and Ile reveal a lock-and-key mechanism for amino acid discrimination
Biochem.J., 394, 2006
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2H88
 | | Avian Mitochondrial Respiratory Complex II at 1.8 Angstrom Resolution | | 分子名称: | AZIDE ION, FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, ... | | 著者 | Huang, L.S, Shen, J.T, Wang, A.C, Berry, E.A. | | 登録日 | 2006-06-06 | | 公開日 | 2006-06-20 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Crystallographic studies of the binding of ligands to the dicarboxylate site of Complex II, and the identity of the ligand in the
Biochim.Biophys.Acta, 1757
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3UAJ
 | | Crystal structure of the envelope glycoprotein ectodomain from dengue virus serotype 4 in complex with the fab fragment of the chimpanzee monoclonal antibody 5H2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain, monoclonal antibody 5H2, ... | | 著者 | Cockburn, J.J.B, Stura, E.A, Navarro-Sanchez, M.E, Rey, F.A. | | 登録日 | 2011-10-21 | | 公開日 | 2011-12-14 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.232 Å) | | 主引用文献 | Structural insights into the neutralization mechanism of a higher primate antibody against dengue virus.
Embo J., 31, 2012
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1SF2
 | | Structure of E. coli gamma-aminobutyrate aminotransferase | | 分子名称: | 1,2-ETHANEDIOL, 4-aminobutyrate aminotransferase, PYRIDOXAL-5'-PHOSPHATE, ... | | 著者 | Liu, W, Peterson, P.E, Carter, R.J, Zhou, X, Langston, J.A, Fisher, A.J, Toney, M.D. | | 登録日 | 2004-02-19 | | 公開日 | 2004-09-14 | | 最終更新日 | 2018-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structures of unbound and aminooxyacetate-bound Escherichia coli gamma-aminobutyrate aminotransferase.
Biochemistry, 43, 2004
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5C0U
 | | Crystal structure of the copper-bound form of MerB mutant D99S | | 分子名称: | Alkylmercury lyase, BROMIDE ION, COPPER (II) ION | | 著者 | Wahba, H.M, Lecoq, L, Stevenson, M, Mansour, A, Cappadocia, L, Lafrance-Vanasse, J, Wilkinson, K.J, Sygusch, J, Wilcox, D.E, Omichinski, J.G. | | 登録日 | 2015-06-12 | | 公開日 | 2016-02-03 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Structural and Biochemical Characterization of a Copper-Binding Mutant of the Organomercurial Lyase MerB: Insight into the Key Role of the Active Site Aspartic Acid in Hg-Carbon Bond Cleavage and Metal Binding Specificity.
Biochemistry, 55, 2016
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4IB4
 | | Crystal structure of the chimeric protein of 5-HT2B-BRIL in complex with ergotamine | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHOLESTEROL, ... | | 著者 | Wacker, D, Wang, C, Katritch, V, Han, G.W, Huang, X, Vardy, E, McCorvy, J.D, Jiang, Y, Chu, M, Siu, F.Y, Liu, W, Xu, H.E, Cherezov, V, Roth, B.L, Stevens, R.C, GPCR Network (GPCR) | | 登録日 | 2012-12-07 | | 公開日 | 2013-03-13 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural features for functional selectivity at serotonin receptors.
Science, 340, 2013
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7EQX
 | | Crystal structure of an Aedes aegypti procarboxypeptidase B1 | | 分子名称: | Carboxypeptidase B, ZINC ION | | 著者 | Choong, Y.K, Gavor, E, Jobichen, C, Sivaraman, J. | | 登録日 | 2021-05-05 | | 公開日 | 2021-11-10 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | Structure of Aedes aegypti procarboxypeptidase B1 and its binding with Dengue virus for controlling infection.
Life Sci Alliance, 5, 2022
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