PDB: 30867 件ウェブページステータス検索Chemie searchBIRD

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5TEF	Crystal structure of Gemin5 WD40 repeats in complex with m7GpppG 分子名称: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, GLYCEROL, Gem-associated protein 5, ... 著者 Chao, X, Tempel, W, Bian, C, He, H, Cerovina, T, Seitova, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) 登録日 2016-09-21 公開日 2016-10-19 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural insights into Gemin5-guided selection of pre-snRNAs for snRNP assembly. Genes Dev., 30, 2016
5TFR	Crystal structure of Zika Virus NS5 protein 分子名称: Genome polyprotein, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION 著者 Longenecker, K.L, Upadhyay, A.K. 登録日 2016-09-26 公開日 2016-10-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Crystal structure of full-length Zika virus NS5 protein reveals a conformation similar to Japanese encephalitis virus NS5. Acta Crystallogr F Struct Biol Commun, 73, 2017
5TIL	Murine class I major histocompatibility complex H-2 Db in complex with LCMV-derived GP33 altered peptide V3P and T-cell receptor P14 分子名称: Alpha chain of murine P14 T cell receptor, Beta chain of murine T cell receptor P14, Beta-2-microglobulin, ... 著者 Achour, A, Sandalova, T, Allerbring, E.B. 登録日 2016-10-03 公開日 2017-11-01 実験手法 X-RAY DIFFRACTION (2.83 Å) 主引用文献 Ternary complexes of TCR P14 give insights into the mechanisms behind reestablishment of CTL responses against a viral escape mutant To be published
5TJ2	Gasdermin-B C-terminal domain containing the polymorphism residues Gly299:Ser306 fused to maltose binding protein 分子名称: Sugar ABC transporter substrate-binding protein,Gasdermin-B fusion protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose 著者 Chao, L.K, Herzberg, O. 登録日 2016-10-03 公開日 2017-02-01 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Human Gasdermin-B and disease: Sulfatide Binding, Caspase cleavage, and Structural impact of Asthma- and IBS-Associated Polymorphism Proc.Natl.Acad.Sci.Usa, 2017
5TJR	X-ray Crystal structure of a methylmalonate semialdehyde dehydrogenase from Pseudomonas sp. AAC 分子名称: ADENOSINE-5'-DIPHOSPHATE, Methylmalonate-semialdehyde dehydrogenase 著者 Peat, T.S, Newman, J. 登録日 2016-10-05 公開日 2017-01-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Structural Analysis Provides Mechanistic Insight into Nicotine Oxidoreductase from Pseudomonas putida. Biochemistry, 55, 2016
5T6E	Crystal structure of Aspergillus fumigatus N-myristoyl transferase in complex with myristoyl CoA and a dichloro-dimethylpyridyl-methoxy-phenyl-pyridyl-piperazine ligand 分子名称: 1-(4-{3,5-dichloro-4-[(2,4-dimethylpyridin-3-yl)methoxy]phenyl}pyridin-2-yl)piperazine, Glycylpeptide N-tetradecanoyltransferase, TETRADECANOYL-COA 著者 Robinson, D.A, Wyatt, P.G. 登録日 2016-09-01 公開日 2017-09-13 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Design and Synthesis of Brain Penetrant Trypanocidal N-Myristoyltransferase Inhibitors. J. Med. Chem., 60, 2017
5T6M	Structure of the tryptophan synthase b-subunit from Pyroccus furiosus with b-methyltryptophan non-covalently bound 分子名称: (betaS)-beta-methyl-L-tryptophan, PHOSPHATE ION, SODIUM ION, ... 著者 Buller, A.R, van Roye, P, Arnold, F.H. 登録日 2016-09-01 公開日 2016-12-21 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Tryptophan Synthase Uses an Atypical Mechanism To Achieve Substrate Specificity. Biochemistry, 55, 2016
5TBX	hnRNP A18 RNA Recognition Motif 分子名称: ACETATE ION, Cold-inducible RNA-binding protein, NICKEL (II) ION 著者 Coburn, K.M, Melville, Z, Aligholizadeh, E, Roth, B.M, Varney, K.M, Weber, D.J. 登録日 2016-09-13 公開日 2017-04-12 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.767 Å) 主引用文献 Crystal structure of the human heterogeneous ribonucleoprotein A18 RNA-recognition motif. Acta Crystallogr F Struct Biol Commun, 73, 2017
5TDN	Crystal structure of the Fab fragment of anti-HER2 antibody 4D5 with redesigned heavy and light chain interfaces 分子名称: GLYCEROL, anti-HER2 Fab Heavy Chain, anti-HER2 Fab Light Chain 著者 Yin, Y, Carter, P.J. 登録日 2016-09-19 公開日 2016-12-07 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Crystal structure of the Fab fragment of anti-HER2 antibody 4D5 with redesigned heavy and light chain interfaces To Be Published
5TFU	Structure of cytochrome P450 2D6 (CYP2D6) BACE1 inhibitor complex 分子名称: (4S,6R)-4-[2,4-difluoro-5-({[1-(trifluoromethyl)cyclopropyl]amino}methyl)phenyl]-4,6-dimethyl-5,6-dihydro-4H-1,3-thiazin-2-amine, Cytochrome P450 2D6, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Hsu, M.H, Johnson, E.F. 登録日 2016-09-26 公開日 2017-01-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Aminomethyl-Derived Beta Secretase (BACE1) Inhibitors: Engaging Gly230 without an Anilide Functionality. J. Med. Chem., 60, 2017
5THP	Rhodocetin in complex with the integrin alpha2-A domain 分子名称: CHLORIDE ION, GLYCEROL, Integrin alpha-2, ... 著者 McDougall, M, Orriss, G.L, Stetefeld, J. 登録日 2016-09-30 公開日 2017-08-02 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.006 Å) 主引用文献 Dramatic and concerted conformational changes enable rhodocetin to block alpha 2 beta 1 integrin selectively. PLoS Biol., 15, 2017
5T63	The HhoA protease from Synechocystis sp. PCC 6803 分子名称: ALA-ALA-ALA-ALA, MAGNESIUM ION, Putative serine protease HhoA 著者 Persson, K, Hall, M, Funk, C. 登録日 2016-09-01 公開日 2017-01-25 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The HhoA protease from Synechocystis sp. PCC 6803 - Novel insights into structure and activity regulation. J. Struct. Biol., 198, 2017
5T69	The HhoA protease from Synechocystis sp. PCC 6803, active site mutant 分子名称: ACETATE ION, MAGNESIUM ION, Putative serine protease HhoA 著者 Persson, K, Hall, M, Funk, C. 登録日 2016-09-01 公開日 2017-01-25 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The HhoA protease from Synechocystis sp. PCC 6803 - Novel insights into structure and activity regulation. J. Struct. Biol., 198, 2017
5T6D	2.10 A resolution structure of Norovirus 3CL protease in complex with the dipeptidyl inhibitor 7l (hexagonal form) 分子名称: 3-cyclohexyl-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-N~2~-{[3-(4-methoxyphenoxy)propyl]sulfonyl}-L- alaninamide, Genome polyprotein 著者 Lovell, S, Battaile, K.P, Mehzabeen, N, Kankanamalage, A.C.G, Kim, Y, Rathnayake, A.D, Damalanka, V.C, Weerawarna, P.M, Doyle, S.T, Alsoudi, A.F, Dissanayake, D.M.P, Chang, K.-O, Groutas, W.C. 登録日 2016-09-01 公開日 2016-11-23 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure-based exploration and exploitation of the S4 subsite of norovirus 3CL protease in the design of potent and permeable inhibitors. Eur J Med Chem, 126, 2016
5T6J	Structure of the MIND Complex Shows a Regulatory Focus of Yeast Kinetochore Assembly 分子名称: Kinetochore protein SPC24, Kinetochore protein SPC25, Kinetochore-associated protein DSN1 著者 Valverde, R, Jenni, S, Dimitrova, Y, Khin, Y, Harrison, S.C. 登録日 2016-09-01 公開日 2016-11-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.752 Å) 主引用文献 Structure of the MIND Complex Defines a Regulatory Focus for Yeast Kinetochore Assembly. Cell, 167, 2016
5T5U	Crystal structure of Aspergillus fumigatus N-myristoyl transferase in complex with myristoyl CoA and a methylpyridyl-dipihenyl-pyridine ligand 分子名称: 2-methyl-3-({[3'-(piperidin-4-yl)[1,1'-biphenyl]-4-yl]oxy}methyl)pyridine, Glycylpeptide N-tetradecanoyltransferase, TETRADECANOYL-COA 著者 Robinson, D.A, Wyatt, P.G. 登録日 2016-08-31 公開日 2017-09-13 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Design and Synthesis of Brain Penetrant Trypanocidal N-Myristoyltransferase Inhibitors. J. Med. Chem., 60, 2017
5T6F	1.90 A resolution structure of Norovirus 3CL protease in complex with the dipeptidyl inhibitor 7l (orthorhombic P form) 分子名称: 3-cyclohexyl-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-N~2~-{[3-(4-methoxyphenoxy)propyl]sulfonyl}-L- alaninamide, Genome polyprotein 著者 Lovell, S, Battaile, K.P, Mehzabeen, N, Kankanamalage, A.C.G, Kim, Y, Rathnayake, A.D, Damalanka, V.C, Weerawarna, P.M, Doyle, S.T, Alsoudi, A.F, Dissanayake, D.M.P, Chang, K.-O, Groutas, W.C. 登録日 2016-09-01 公開日 2016-11-23 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure-based exploration and exploitation of the S4 subsite of norovirus 3CL protease in the design of potent and permeable inhibitors. Eur J Med Chem, 126, 2016

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