PDB: 46006 件ウェブページステータス検索Chemie searchBIRD

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7N8B	Cycloheximide bound vacant 80S structure isolated from cbf5-D95A 分子名称: 18S RIBOSOMAL RNA, 25S, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ... 著者 Rai, J, Zhao, Y, Li, H. 登録日 2021-06-14 公開日 2022-05-11 最終更新日 2022-07-20 実験手法 ELECTRON MICROSCOPY (3.05 Å) 主引用文献 CryoEM structures of pseudouridine-free ribosome suggest impacts of chemical modifications on ribosome conformations. Structure, 30, 2022
8KGF	Structure of AmCas12a with crRNA 分子名称: CRISPR-associated endonuclease Cas12a, MAGNESIUM ION, RNA (44-MER) 著者 Feng, Y, Zhang, X, Shi, J, Ma, P, Tang, J, Huang, X. 登録日 2023-08-18 公開日 2024-09-04 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 A novel CRISPR/Cas12a in complex with a crRNA. To Be Published
5HVS	Crystal Structure of Macrophage Migration Inhibitory Factor (MIF) with a Biaryltriazole Inhibitor (3i-305) 分子名称: 3-({2-[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]quinolin-5-yl}oxy)benzoic acid, GLYCEROL, Macrophage migration inhibitory factor, ... 著者 Robertson, M.J, Jorgensen, W.L. 登録日 2016-01-28 公開日 2016-06-29 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 A Fluorescence Polarization Assay for Binding to Macrophage Migration Inhibitory Factor and Crystal Structures for Complexes of Two Potent Inhibitors. J.Am.Chem.Soc., 138, 2016
8P83	Cryo-EM structure of full-length human UBR5 (homotetramer) 分子名称: E3 ubiquitin-protein ligase UBR5 著者 Aguirre, J.D, Kater, L, Kempf, G, Cavadini, S, Thoma, N.H. 登録日 2023-05-31 公開日 2023-06-14 最終更新日 2023-08-16 実験手法 ELECTRON MICROSCOPY (3.87 Å) 主引用文献 UBR5 forms ligand-dependent complexes on chromatin to regulate nuclear hormone receptor stability. Mol.Cell, 83, 2023
1ZU1	Solution Structure of the N-terminal Zinc Fingers of the Xenopus laevis double stranded RNA binding protein ZFa 分子名称: RNA binding protein ZFa, ZINC ION 著者 Moller, H.M, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E. 登録日 2005-05-29 公開日 2005-09-20 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure of the N-terminal zinc fingers of the Xenopus laevis double-stranded RNA-binding protein ZFa J.Mol.Biol., 351, 2005
3K6G	Crystal structure of Rap1 and TRF2 complex 分子名称: Telomeric repeat-binding factor 2, Telomeric repeat-binding factor 2-interacting protein 1 著者 Chen, Y, Rai, R, Yang, Y.T, Zheng, H, Chang, S, Lei, M. 登録日 2009-10-08 公開日 2010-10-13 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 A conserved motif within RAP1 has diversified roles in telomere protection and regulation in different organisms. Nat.Struct.Mol.Biol., 18, 2011
5HVT	Crystal Structure of Macrophage Migration Inhibitory Factor (MIF) with a Potent Inhibitor (NVS-2) 分子名称: 7-hydroxy-3-(4-methoxyphenyl)-3,4-dihydro-2H-1,3-benzoxazin-2-one, GLYCEROL, ISOPROPYL ALCOHOL, ... 著者 Robertson, M.J, Jorgensen, W.L. 登録日 2016-01-28 公開日 2016-06-29 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 A Fluorescence Polarization Assay for Binding to Macrophage Migration Inhibitory Factor and Crystal Structures for Complexes of Two Potent Inhibitors. J.Am.Chem.Soc., 138, 2016
3I5Z	Crystal structure of ERK2 bound to (S)-N-(2-hydroxy-1-phenylethyl)-4-(5-methyl-2-(phenylamino)pyrimidin-4-yl)-1H-pyrrole-2-carboxamide 分子名称: Mitogen-activated protein kinase 1, N-[(1S)-2-hydroxy-1-phenylethyl]-4-[5-methyl-2-(phenylamino)pyrimidin-4-yl]-1H-pyrrole-2-carboxamide, SULFATE ION 著者 Jacobs, M.D, Xie, X. 登録日 2009-07-06 公開日 2010-01-12 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure-guided design of potent and selective pyrimidylpyrrole inhibitors of extracellular signal-regulated kinase (ERK) using conformational control. J.Med.Chem., 52, 2009
7NAQ	Human PA200-20S proteasome complex 分子名称: INOSITOL HEXAKISPHOSPHATE, Proteasome activator complex subunit 4, Proteasome subunit alpha type-1, ... 著者 Zhao, J, Makhija, S, Huang, B, Cheng, Y. 登録日 2021-06-22 公開日 2022-11-02 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural insights into the human PA28-20S proteasome enabled by efficient tagging and purification of endogenous proteins. Proc.Natl.Acad.Sci.USA, 119, 2022
5D8B	Crystal structure of T. thermophilus ribosome containing a P-site wobble mismatch 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Svidritskiy, E, Korostelev, A.A. 登録日 2015-08-17 公開日 2015-10-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.63 Å) 主引用文献 Ribosome Structure Reveals Preservation of Active Sites in the Presence of a P-Site Wobble Mismatch. Structure, 23, 2015
7NAD	State E2 nucleolar 60S ribosomal biogenesis intermediate - Spb4 local refinement model 分子名称: 25S rRNA, 5.8S rRNA, 60S ribosomal protein L17-A, ... 著者 Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P. 登録日 2021-06-21 公開日 2022-11-09 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.04 Å) 主引用文献 Sequence-specific remodeling of a topologically complex RNP substrate by Spb4. Nat.Struct.Mol.Biol., 29, 2022
4EZ2	Crystal Structure of d(CCGGGACCGG)4 as a four-way junction at 1.6 angstrom resolution 分子名称: 5'-D(*CP*CP*GP*GP*GP*AP*CP*CP*GP*G)-3', SODIUM ION 著者 Chakraborty, A, Mandal, P.K, Gautham, N. 登録日 2012-05-02 公開日 2012-10-17 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure of d(CCGGGACCGG)(4) as a four-way junction at 1.6 A resolution: new insights into solvent interactions. Acta Crystallogr.,Sect.F, 68, 2012
8C3K	PaaR2 N-terminal domin in complex with nanobody 33 分子名称: Nanobody 33, Phage repressor protein CI 著者 Loris, R, Prolic-Kalinsek, M. 登録日 2022-12-26 公開日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.74972475 Å) 主引用文献 PaaR2, the CI equivalent in Escherichia coli O157:H7 cryptic prophage CP-933P To be published
8EWI	Structure of the human UBR5 HECT-type E3 ubiquitin ligase in a tetrameric form 分子名称: E3 ubiquitin-protein ligase UBR5, ZINC ION 著者 Wang, F, He, Q, Lin, G, Li, H. 登録日 2022-10-23 公開日 2023-04-19 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structure of the human UBR5 E3 ubiquitin ligase. Structure, 31, 2023
5DDJ	Crystal structure of recombinant foot-and-mouth-disease virus O1M-S2093Y empty capsid 分子名称: Foot and mouth disease virus, VP1, VP2, ... 著者 Kotecha, A, Seago, J, Scott, K, Burman, A, Loureiro, S, Ren, J, Porta, C, Ginn, H.M, Jackson, T, Perez-Martin, E, Siebert, C.A, Paul, G, Huiskonen, J.T, Jones, I.M, Esnouf, R.M, Fry, E.E, Maree, F.F, Charleston, B, Stuart, D.I. 登録日 2015-08-25 公開日 2015-09-23 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Structure-based energetics of protein interfaces guides foot-and-mouth disease virus vaccine design. Nat.Struct.Mol.Biol., 22, 2015
6VMT	Leishmania major Programmed Cell Death Protein 5 Homolog 分子名称: Programmed Cell Death Protein 5 Homolog 著者 Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP) 登録日 2020-01-28 公開日 2020-02-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.501 Å) 主引用文献 Leishmania major Programmed Cell Death Protein 5 Homolog To be published
7MPJ	Stm1 bound vacant 80S structure isolated from wild-type 分子名称: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... 著者 Rai, J, Zhao, Y, Li, H. 登録日 2021-05-04 公開日 2022-05-11 最終更新日 2023-12-13 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 CryoEM structures of pseudouridine-free ribosome suggest impacts of chemical modifications on ribosome conformations. Structure, 30, 2022
8B9I	Cryo-EM structure of MLE in complex with ADP:AlF4 and UUC RNA 分子名称: ADENOSINE-5'-DIPHOSPHATE, Dosage compensation regulator, MAGNESIUM ION, ... 著者 Jagtap, P.K.A, Hennig, J. 登録日 2022-10-06 公開日 2023-10-18 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.95 Å) 主引用文献 Structural basis of RNA-induced autoregulation of the DExH-type RNA helicase maleless. Mol.Cell, 83, 2023
8B9G	Cryo-EM structure of MLE in complex with ADP:AlF4 and U10 RNA 分子名称: ADENOSINE-5'-DIPHOSPHATE, Dosage compensation regulator, RNA (5'-R(P*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3'), ... 著者 Jagtap, P.K.A, Hennig, J. 登録日 2022-10-06 公開日 2023-10-18 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.86 Å) 主引用文献 Structural basis of RNA-induced autoregulation of the DExH-type RNA helicase maleless. Mol.Cell, 83, 2023
8CVS	Human PA200-20S proteasome with MG-132 分子名称: INOSITOL HEXAKISPHOSPHATE, N-[(benzyloxy)carbonyl]-L-leucyl-N-[(2S)-4-methyl-1-oxopentan-2-yl]-L-leucinamide, Proteasome activator complex subunit 4, ... 著者 Zhao, J. 登録日 2022-05-18 公開日 2022-11-02 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural insights into the human PA28-20S proteasome enabled by efficient tagging and purification of endogenous proteins. Proc.Natl.Acad.Sci.USA, 119, 2022
8B9L	Cryo-EM structure of MLE 分子名称: Dosage compensation regulator 著者 Jagtap, P.K.A, Hennig, J. 登録日 2022-10-06 公開日 2023-10-18 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.45 Å) 主引用文献 Structural basis of RNA-induced autoregulation of the DExH-type RNA helicase maleless. Mol.Cell, 83, 2023
8B9K	Cryo-EM structure of MLE in complex with ADP:AlF4 and SL7modUUC RNA 分子名称: ADENOSINE-5'-DIPHOSPHATE, Dosage compensation regulator, SL7modUUC, ... 著者 Jagtap, P.K.A, Hennig, J. 登録日 2022-10-06 公開日 2023-10-18 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (4.04 Å) 主引用文献 Structural basis of RNA-induced autoregulation of the DExH-type RNA helicase maleless. Mol.Cell, 83, 2023
8B9J	Cryo-EM structure of MLE in complex with ADP:AlF4 分子名称: ADENOSINE-5'-DIPHOSPHATE, Dosage compensation regulator, MAGNESIUM ION, ... 著者 Jagtap, P.K.A, Hennig, J. 登録日 2022-10-06 公開日 2023-10-18 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.45 Å) 主引用文献 Structural basis of RNA-induced autoregulation of the DExH-type RNA helicase maleless. Mol.Cell, 83, 2023
7NRC	Structure of the yeast Gcn1 bound to a leading stalled 80S ribosome with Rbg2, Gir2, A- and P-tRNA and eIF5A 分子名称: 18S rRNA (1771-MER), 25S rRNA (3184-MER), 40S ribosomal protein S0-A, ... 著者 Pochopien, A.A, Beckert, B, Wilson, D.N. 登録日 2021-03-03 公開日 2021-05-05 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structure of Gcn1 bound to stalled and colliding 80S ribosomes. Proc.Natl.Acad.Sci.USA, 118, 2021
6W6M	Single particle cryoEM structure of V. cholerae Type IV competence pilus secretin PilQ 分子名称: Type IV pilus secretin PilQ family protein 著者 Sazinsky, M.H, Weaver, S.J. 登録日 2020-03-17 公開日 2020-10-14 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 CryoEM structure of the type IVa pilus secretin required for natural competence in Vibrio cholerae. Nat Commun, 11, 2020

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