6OEN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6oen by Molmil](/molmil-images/mine/6oen) | Cryo-EM structure of mouse RAG1/2 PRC complex (DNA1) | 分子名称: | CALCIUM ION, DNA (46-MER), DNA (57-MER), ... | 著者 | Chen, X, Cui, Y, Zhou, Z.H, Yang, W, Gellert, M. | 登録日 | 2019-03-27 | 公開日 | 2020-01-29 | 最終更新日 | 2020-02-26 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Cutting antiparallel DNA strands in a single active site. Nat.Struct.Mol.Biol., 27, 2020
|
|
3ZVK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3zvk by Molmil](/molmil-images/mine/3zvk) | Crystal structure of VapBC2 from Rickettsia felis bound to a DNA fragment from their promoter | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ANTITOXIN OF TOXIN-ANTITOXIN SYSTEM VAPB, DNA, ... | 著者 | Mate, M.J, Ortiz-Lombardia, M, Cambillau, C. | 登録日 | 2011-07-25 | 公開日 | 2011-12-14 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal Structure of the DNA-Bound Vapbc2 Antitoxin/Toxin Pair from Rickettsia Felis. Nucleic Acids Res., 40, 2012
|
|
3ZDC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3zdc by Molmil](/molmil-images/mine/3zdc) | Structure of E. coli ExoIX in complex with the palindromic 5ov4 DNA oligonucleotide, potassium and calcium | 分子名称: | 5OV4 DNA, 5'-D(*AP*AP*AP*AP*GP*CP*GP*TP*AP*CP*GP*CP)-3', ACETATE ION, ... | 著者 | Hemsworth, G.R, Anstey-Gilbert, C.S, Flemming, C.S, Hodskinson, M.R.G, Zhang, J, Sedelnikova, S.E, Stillman, T.J, Sayers, J.R, Artymiuk, P.J. | 登録日 | 2012-11-26 | 公開日 | 2013-07-10 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | The Structure of E. Coli Exoix - Implications for DNA Binding and Catalysis in Flap Endonucleases Nucleic Acids Res., 41, 2013
|
|
5BK4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5bk4 by Molmil](/molmil-images/mine/5bk4) | Cryo-EM structure of Mcm2-7 double hexamer on dsDNA | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA (60-mer), strand 1, ... | 著者 | Li, H, Yuan, Z, Bai, L. | 登録日 | 2017-09-12 | 公開日 | 2017-10-25 | 最終更新日 | 2020-01-08 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Cryo-EM structure of Mcm2-7 double hexamer on DNA suggests a lagging-strand DNA extrusion model. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
1KO9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ko9 by Molmil](/molmil-images/mine/1ko9) | Native Structure of the Human 8-oxoguanine DNA Glycosylase hOGG1 | 分子名称: | 8-oxoguanine DNA glycosylase, SULFATE ION | 著者 | Bjoras, M, Seeberg, E, Luna, L, Pearl, L.H, Barrett, T.E. | 登録日 | 2001-12-20 | 公開日 | 2002-01-09 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Reciprocal "flipping" underlies substrate recognition and catalytic activation by the human 8-oxo-guanine DNA glycosylase. J.Mol.Biol., 317, 2002
|
|
6EDC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6edc by Molmil](/molmil-images/mine/6edc) | hcGAS-16bp dsDNA complex | 分子名称: | Cyclic GMP-AMP synthase, DNA (5'-D(*AP*AP*AP*TP*TP*GP*CP*CP*GP*AP*AP*GP*AP*CP*GP*AP*A)-3'), DNA (5'-D(*TP*TP*CP*GP*TP*CP*TP*TP*CP*GP*GP*CP*AP*AP*T)-3'), ... | 著者 | Xie, W, Lama, L, Adura, C, Glickman, J.F, Tuschl, T, Patel, D.J. | 登録日 | 2018-08-09 | 公開日 | 2019-05-29 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.712 Å) | 主引用文献 | Human cGAS catalytic domain has an additional DNA-binding interface that enhances enzymatic activity and liquid-phase condensation. Proc.Natl.Acad.Sci.USA, 116, 2019
|
|
5XGT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5xgt by Molmil](/molmil-images/mine/5xgt) | |
2OZM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ozm by Molmil](/molmil-images/mine/2ozm) | Crystal structure of RB69 gp43 in complex with DNA with 5-NITP opposite an abasic site analog | 分子名称: | 1-{2-DEOXY-5-O-[(R)-HYDROXY{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}PHOSPHORYL]-BETA-D-ERYTHRO-PENTOFURANOSYL}-5-NITRO -1H-INDOLE, DNA polymerase, MAGNESIUM ION, ... | 著者 | Zahn, K.E, Belrhali, H, Wallace, S.S, Doublie, S. | 登録日 | 2007-02-26 | 公開日 | 2007-10-23 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | 主引用文献 | Caught Bending the A-Rule: crystal structures of translesion DNA synthesis with a non-natural nucleotide Biochemistry, 46, 2007
|
|
2OZS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ozs by Molmil](/molmil-images/mine/2ozs) | Crystal structure of RB69 gp43 in complex with DNA with dATP opposite dTMP | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA polymerase, MAGNESIUM ION, ... | 著者 | Zahn, K.E, Belrhali, H, Wallace, S.S, Doublie, S. | 登録日 | 2007-02-27 | 公開日 | 2007-10-23 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Caught bending the a-rule: crystal structures of translesion DNA synthesis with a non-natural nucleotide. Biochemistry, 46, 2007
|
|
6OEP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6oep by Molmil](/molmil-images/mine/6oep) | Cryo-EM structure of mouse RAG1/2 12RSS-NFC/23RSS-PRC complex (DNA1) | 分子名称: | CALCIUM ION, DNA (46-MER), DNA (57-MER), ... | 著者 | Chen, X, Cui, Y, Zhou, Z.H, Yang, W, Gellert, M. | 登録日 | 2019-03-27 | 公開日 | 2020-01-29 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Cutting antiparallel DNA strands in a single active site. Nat.Struct.Mol.Biol., 27, 2020
|
|
1UA0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ua0 by Molmil](/molmil-images/mine/1ua0) | Aminofluorene DNA adduct at the pre-insertion site of a DNA polymerase | 分子名称: | 2-AMINOFLUORENE, DNA polymerase I, DNA primer strand, ... | 著者 | Hsu, G.W, Kiefer, J.R, Becherel, O.J, Fuchs, R.P.P, Beese, L.S. | 登録日 | 2004-08-11 | 公開日 | 2004-09-28 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Observing translesion synthesis of an aromatic amine DNA adduct by a high-fidelity DNA polymerase J.Biol.Chem., 279, 2004
|
|
2P2R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2p2r by Molmil](/molmil-images/mine/2p2r) | Crystal structure of the third KH domain of human Poly(C)-Binding Protein-2 in complex with C-rich strand of human telomeric DNA | 分子名称: | 6-AMINOPYRIMIDIN-2(1H)-ONE, C-rich strand of human telomeric DNA, Poly(rC)-binding protein 2 | 著者 | James, T.L, Stroud, R.M, Du, Z, Fenn, S, Tjhen, R, Lee, J.K. | 登録日 | 2007-03-07 | 公開日 | 2007-06-12 | 最終更新日 | 2019-07-24 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structure of the third KH domain of human poly(C)-binding protein-2 in complex with a C-rich strand of human telomeric DNA at 1.6 A resolution. Nucleic Acids Res., 35, 2007
|
|
4MKY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4mky by Molmil](/molmil-images/mine/4mky) | |
1UDH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1udh by Molmil](/molmil-images/mine/1udh) | |
1UDG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1udg by Molmil](/molmil-images/mine/1udg) | |
9ENP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 9enp by Molmil](/molmil-images/mine/9enp) | HSV-1 DNA polymerase-processivity factor complex in exonuclease state with 1-bp DNA mismatch | 分子名称: | CALCIUM ION, DNA (46-MER), DNA (67-MER), ... | 著者 | Gustavsson, E, Grunewald, K, Elias, P, Hallberg, B.M. | 登録日 | 2024-03-13 | 公開日 | 2024-05-29 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.12 Å) | 主引用文献 | Dynamics of the Herpes simplex virus DNA polymerase holoenzyme during DNA synthesis and proof-reading revealed by Cryo-EM. Nucleic Acids Res., 52, 2024
|
|
9ENQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 9enq by Molmil](/molmil-images/mine/9enq) | HSV-1 DNA polymerase-processivity factor complex in exonuclease state active site with 1-bp DNA mismatch | 分子名称: | CALCIUM ION, DNA (46-MER), DNA (67-MER), ... | 著者 | Gustavsson, E, Grunewald, K, Elias, P, Hallberg, B.M. | 登録日 | 2024-03-13 | 公開日 | 2024-05-29 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.12 Å) | 主引用文献 | Dynamics of the Herpes simplex virus DNA polymerase holoenzyme during DNA synthesis and proof-reading revealed by Cryo-EM. Nucleic Acids Res., 52, 2024
|
|
5B43
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5b43 by Molmil](/molmil-images/mine/5b43) | Crystal structure of Acidaminococcus sp. Cpf1 in complex with crRNA and target DNA | 分子名称: | 1,2-ETHANEDIOL, CRISPR-associated endonuclease Cpf1, DNA (34-MER), ... | 著者 | Yamano, T, Nishimasu, H, Hirano, H, Nakane, T, Ishitani, R, Nureki, O. | 登録日 | 2016-03-30 | 公開日 | 2016-05-04 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal Structure of Cpf1 in Complex with Guide RNA and Target DNA Cell, 165, 2016
|
|
6L84
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6l84 by Molmil](/molmil-images/mine/6l84) | Complex of DNA polymerase IV and D-DNA duplex | 分子名称: | CALCIUM ION, DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*CP*C)-3'), DNA (5'-D(P*CP*GP*GP*AP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3'), ... | 著者 | Chung, H.S, An, J, Hwang, D. | 登録日 | 2019-11-04 | 公開日 | 2020-07-08 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.602 Å) | 主引用文献 | The crystal structure of a natural DNA polymerase complexed with mirror DNA. Chem.Commun.(Camb.), 56, 2020
|
|
3ZM7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3zm7 by Molmil](/molmil-images/mine/3zm7) | CRYSTAL STRUCTURE OF THE ATPASE REGION OF Mycobacterium tuberculosis GyrB WITH AMPPCP | 分子名称: | DNA GYRASE SUBUNIT B, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | 著者 | Agrawal, A, Roue, M, Spitzfaden, C, Petrella, S, Aubry, A, Volker, C, Mossakowska, D, Hann, M, Bax, B, Mayer, C. | 登録日 | 2013-02-05 | 公開日 | 2013-09-18 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Mycobacterium Tuberculosis DNA Gyrase ATPase Domain Structures Suggest a Dissociative Mechanism that Explains How ATP Hydrolysis is Coupled to Domain Motion. Biochem.J., 456, 2013
|
|
3ZKD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3zkd by Molmil](/molmil-images/mine/3zkd) | CRYSTAL STRUCTURE OF THE ATPASE REGION OF Mycobacterium tuberculosis GyrB WITH AMPPNP | 分子名称: | DNA GYRASE SUBUNIT B, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | 著者 | Agrawal, A, Roue, M, Spitzfaden, C, Petrella, S, Aubry, A, Volker, C, Mossakowska, D, Hann, M, Bax, B, Mayer, C. | 登録日 | 2013-01-22 | 公開日 | 2013-09-18 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Mycobacterium Tuberculosis DNA Gyrase ATPase Domain Structures Suggest a Dissociative Mechanism that Explains How ATP Hydrolysis is Coupled to Domain Motion. Biochem.J., 456, 2013
|
|
5OS9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5os9 by Molmil](/molmil-images/mine/5os9) | |
8I6K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8i6k by Molmil](/molmil-images/mine/8i6k) | Structure of hMNDA HIN with dsDNA | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, DNA (5'-D(*GP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*C)-3'), ... | 著者 | Li, Y.L, Jin, T.C. | 登録日 | 2023-01-28 | 公開日 | 2023-07-19 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural mechanism of dsDNA recognition by the hMNDA HIN domain: New insights into the DNA-binding model of a PYHIN protein. Int.J.Biol.Macromol., 245, 2023
|
|
2DTU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2dtu by Molmil](/molmil-images/mine/2dtu) | Crystal structure of the beta hairpin loop deletion variant of RB69 gp43 in complex with DNA containing an abasic site analog | 分子名称: | 5'-D(*CP*GP*(3DR)P*CP*TP*TP*AP*TP*GP*AP*CP*AP*GP*CP*CP*GP*CP*G)-3', 5'-D(*GP*CP*GP*GP*CP*TP*GP*TP*CP*AP*TP*AP*AP*GP*A)-3', DNA polymerase | 著者 | Aller, P, Hogg, M, Konigsberg, W, Wallace, S.S, Doublie, S. | 登録日 | 2006-07-15 | 公開日 | 2006-12-05 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | 主引用文献 | Structural and biochemical investigation of the role in proofreading of a beta hairpin loop found in the exonuclease domain of a replicative DNA polymerase of the B family. J.Biol.Chem., 282, 2007
|
|
6OGK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ogk by Molmil](/molmil-images/mine/6ogk) | MeCP2 MBD in complex with DNA | 分子名称: | CALCIUM ION, DNA (5'-D(*CP*GP*GP*AP*GP*TP*GP*TP*AP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*TP*AP*(5CM)P*AP*CP*TP*CP*CP*G)-3'), ... | 著者 | Lei, M, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium, Structural Genomics Consortium (SGC) | 登録日 | 2019-04-02 | 公開日 | 2019-05-01 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Plasticity at the DNA recognition site of the MeCP2 mCG-binding domain. Biochim Biophys Acta Gene Regul Mech, 1862, 2019
|
|