PDB: 494 件ウェブページステータス検索Chemie searchBIRD

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1EFX	STRUCTURE OF A COMPLEX BETWEEN THE HUMAN NATURAL KILLER CELL RECEPTOR KIR2DL2 AND A CLASS I MHC LIGAND HLA-CW3 分子名称: BETA-2-MICROGLOBULIN, HLA-CW3 (HEAVY CHAIN), NATURAL KILLER CELL RECEPTOR KIR2DL2, ... 著者 Boyington, J.C, Motyka, S.A, Schuck, P, Brooks, A.G, Sun, P.D. 登録日 2000-02-10 公開日 2000-06-14 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structure of an NK cell immunoglobulin-like receptor in complex with its class I MHC ligand. Nature, 405, 2000
2QMR	Karyopherin beta2/transportin 分子名称: Transportin-1 著者 Cansizoglu, A.E, Chook, Y.M. 登録日 2007-07-16 公開日 2007-10-30 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Conformational heterogeneity of karyopherin beta2 is segmental Structure, 15, 2007
2VY7	The 627-domain from influenza A virus polymerase PB2 subunit 分子名称: POLYMERASE BASIC PROTEIN 2 著者 Tarendeau, F, Crepin, T, Guilligay, D, Ruigrok, R, Cusack, S, Hart, D. 登録日 2008-07-18 公開日 2008-09-09 最終更新日 2012-06-06 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Host Determinant Residue Lysine 627 Lies on the Surface of a Discrete, Folded Domain of Influenza Virus Polymerase Pb2 Subunit Plos Pathog., 4, 2008
2VY6	Two domains from the C-terminal region of influenza A virus polymerase PB2 subunit 分子名称: POLYMERASE BASIC PROTEIN 2 著者 Tarendeau, F, Crepin, T, Guilligay, D, Ruigrok, R, Cusack, S, Hart, D. 登録日 2008-07-18 公開日 2008-09-09 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Host Determinant Residue Lysine 627 Lies on the Surface of a Discrete, Folded Domain of Influenza Virus Polymerase Pb2 Subunit Plos Pathog., 4, 2008
2VY8	The 627-domain from influenza A virus polymerase PB2 subunit with Glu- 627 分子名称: POLYMERASE BASIC PROTEIN 2 著者 Tarendeau, F, Crepin, T, Guilligay, D, Ruigrok, R, Cusack, S, Hart, D. 登録日 2008-07-19 公開日 2008-09-09 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Host Determinant Residue Lysine 627 Lies on the Surface of a Discrete, Folded Domain of Influenza Virus Polymerase Pb2 Subunit Plos Pathog., 4, 2008
6BJC	TPX2_mini decorated GMPCPP-microtubule 分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... 著者 Zhang, R, Nogales, E. 登録日 2017-11-05 公開日 2017-11-22 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structural insight into TPX2-stimulated microtubule assembly. Elife, 6, 2017
4FGV	Crystal structure of free CRM1 (crystal form 1) 分子名称: Chromosome region maintenance 1 (CRM1) or Exportin 1 (Xpo1) 著者 Monecke, T, Neumann, P, Dickmanns, A, Ficner, R. 登録日 2012-06-05 公開日 2013-01-23 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.941 Å) 主引用文献 Structural basis for cooperativity of CRM1 export complex formation. Proc.Natl.Acad.Sci.USA, 110, 2013
6I3H	Crystal structure of influenza A virus M1 N-terminal domain (G18A mutation) 分子名称: Matrix protein 1, PHOSPHATE ION 著者 Miyake, Y, Keusch, J.J, Decamps, L, Ho-Xuan, H, Iketani, S, Gut, H, Kutay, U, Helenius, A, Yamauchi, Y. 登録日 2018-11-06 公開日 2019-09-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Influenza virus uses transportin 1 for vRNP debundling during cell entry. Nat Microbiol, 4, 2019
3TPQ	Crystal structure of wild-type MAL RPEL domain in complex with five G-actins 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... 著者 Hirano, H, Matsuura, Y. 登録日 2011-09-08 公開日 2011-10-12 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.45 Å) 主引用文献 Sensing actin dynamics: structural basis for G-actin-sensitive nuclear import of MAL Biochem.Biophys.Res.Commun., 414, 2011
5J3V	Crystal structure of human Karyopherin-beta2 bound to the histone H3 tail 分子名称: Histone H3, Transportin-1,Transportin-1 著者 Soniat, M, Chook, Y.M. 登録日 2016-03-31 公開日 2016-09-21 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Karyopherin-beta 2 Recognition of a PY-NLS Variant that Lacks the Proline-Tyrosine Motif. Structure, 24, 2016
8G5V	Empty capsid of Hepatitis B virus 分子名称: Core protein Cp183 著者 Yang, R, Cingolani, G. 登録日 2023-02-14 公開日 2024-01-24 最終更新日 2024-08-21 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structural basis for nuclear import of hepatitis B virus (HBV) nucleocapsid core. Sci Adv, 10, 2024
4C0Q	Transportin 3 in complex with Ran(Q69L)GTP 分子名称: GTP-BINDING NUCLEAR PROTEIN RAN, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Maertens, G, Hare, S, Cherepanov, P. 登録日 2013-08-06 公開日 2014-01-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.42 Å) 主引用文献 Structural Basis for Nuclear Import of Splicing Factors by Human Transportin 3. Proc.Natl.Acad.Sci.USA, 111, 2014
4OO6	Crystal structure of human KAP-beta2 bound to the NLS of HCC1 (Hepato Cellular Carcinoma protein 1) 分子名称: RNA-binding protein 39, Transportin-1 著者 Sampathkumar, P, Brower, A, Soniat, M, Bonanno, J, Hillerich, B, Seidel, R.D, Rout, M.P, Chook, Y.M, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Nucleocytoplasmic Transport: a Target for Cellular Control (NPCXstals) 登録日 2014-01-30 公開日 2014-02-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of human KAP-beta2 bound to the NLS of HCC1 (Hepato Cellular Carcinoma protein 1) to be published
2Z5K	Complex of Transportin 1 with TAP NLS 分子名称: Nuclear RNA export factor 1, PHOSPHATE ION, Transportin-1 著者 Imasaki, T, Shimizu, T, Hashimoto, H, Hidaka, Y, Yamada, M, Kose, S, Imamoto, N, Sato, M. 登録日 2007-07-14 公開日 2007-10-23 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis for substrate recognition and dissociation by human transportin 1 Mol.Cell, 28, 2007
2Z5M	Complex of Transportin 1 with TAP NLS, crystal form 2 分子名称: Nuclear RNA export factor 1, Transportin-1 著者 Imasaki, T, Shimizu, T, Hashimoto, H, Hidaka, Y, Kose, S, Imamoto, N, Yamada, M, Sato, M. 登録日 2007-07-14 公開日 2007-10-23 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis for substrate recognition and dissociation by human transportin 1 Mol.Cell, 28, 2007
2Z5N	Complex of Transportin 1 with hnRNP D NLS 分子名称: Heterogeneous nuclear ribonucleoprotein D0, Transportin-1 著者 Imasaki, T, Shimizu, T, Hashimoto, H, Hidaka, Y, Kose, S, Imamoto, N, Yamada, M, Sato, M. 登録日 2007-07-14 公開日 2007-10-23 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural basis for substrate recognition and dissociation by human transportin 1 Mol.Cell, 28, 2007
2Z5J	Free Transportin 1 分子名称: Transportin-1 著者 Imasaki, T, Shimizu, T, Hashimoto, H, Hidaka, Y, Yamada, M, Sato, M. 登録日 2007-07-13 公開日 2007-10-23 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Structural basis for substrate recognition and dissociation by human transportin 1 Mol.Cell, 28, 2007
2Z5O	Complex of Transportin 1 with JKTBP NLS 分子名称: Heterogeneous nuclear ribonucleoprotein D-like, Transportin-1 著者 Imasaki, T, Shimizu, T, Hashimoto, H, Hidaka, Y, Kose, S, Imamoto, N, Yamada, M, Sato, M. 登録日 2007-07-14 公開日 2007-10-23 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural basis for substrate recognition and dissociation by human transportin 1 Mol.Cell, 28, 2007
7YPZ	Zafirlukast in complex with CRM1-Ran-RanBP1 分子名称: 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, CHLORIDE ION, ... 著者 Sun, Q, Lei, Y. 登録日 2022-08-05 公開日 2023-08-16 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Searching for Novel Noncovalent Nuclear Export Inhibitors through a Drug Repurposing Approach. J.Med.Chem., 66, 2023
2BKA	CC3(TIP30)Crystal Structure 分子名称: 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, GLYCEROL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 El Omari, K, Bird, L.E, Nichols, C.E, Ren, J, Stammers, D.K. 登録日 2005-02-14 公開日 2005-02-21 最終更新日 2016-12-21 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal Structure of Cc3 (Tip30): Implications for its Role as a Tumor Suppressor J.Biol.Chem., 280, 2005
1QG4	CANINE GDP-RAN F72Y MUTANT 分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PROTEIN (RAN) 著者 Kent, H.M, Moore, M.S, Quimby, B.B, Baker, A.M.E, McCoy, A.J, Murphy, G.A, Corbett, A.H, Stewart, M. 登録日 1999-04-20 公開日 1999-06-11 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Engineered mutants in the switch II loop of Ran define the contribution made by key residues to the interaction with nuclear transport factor 2 (NTF2) and the role of this interaction in nuclear protein import. J.Mol.Biol., 289, 1999
3R63	Structure of ERK2 (SPE) mutant (S246E) 分子名称: Mitogen-activated protein kinase 1 著者 Livnah, O, Karamansha, Y. 登録日 2011-03-21 公開日 2011-08-17 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Nuclear ERK translocation is mediated by protein kinase CK2 and accelerated by autophosphorylation. Mol.Cell.Biol., 31, 2011
4WVF	Crystal structure of KPT276 in complex with CRM1-Ran-RanBP1 分子名称: (2E)-3-{3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl}-1-(3,3-difluoroazetidin-1-yl)prop-2-en-1-one, 1,2-ETHANEDIOL, CHLORIDE ION, ... 著者 Sun, Q, Chook, Y. 登録日 2014-11-05 公開日 2015-07-15 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Nuclear export inhibitors avert progression in preclinical models of inflammatory demyelination. Nat.Neurosci., 18, 2015
4FDD	Crystal structure of KAP beta2-PY-NLS 分子名称: RNA-binding protein FUS, Transportin-1 著者 Zhang, Z.C, Chook, Y.M. 登録日 2012-05-28 公開日 2012-07-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural and energetic basis of ALS-causing mutations in the atypical proline-tyrosine nuclear localization signal of the Fused in Sarcoma protein (FUS). Proc.Natl.Acad.Sci.USA, 109, 2012
1GY5	D92N,D94N double point mutant of human Nuclear Transport Factor 2 (NTF2) 分子名称: NUCLEAR TRANSPORT FACTOR 2 著者 Bayliss, R, Stewart, M. 登録日 2002-04-21 公開日 2002-06-20 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural Basis for the Interaction between Ntf2 and Nucleoporin Fxfg Repeats Embo J., 21, 2002

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