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5D8I
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Engineering the Species-Specificity of an Inhibitory Antibody Targeting a Modulator of Tumor Stroma
分子名称: Sulfhydryl oxidase 1
著者Grossman, I, Fass, D.
登録日2015-08-17
公開日2016-02-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Overcoming a species-specificity barrier in development of an inhibitory antibody targeting a modulator of tumor stroma.
Protein Eng.Des.Sel., 29, 2016
3UEM
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BU of 3uem by Molmil
Crystal structure of human PDI bb'a' domains
分子名称: (4S,5S)-1,2-DITHIANE-4,5-DIOL, Protein disulfide-isomerase
著者Yu, J, Wang, C, Huo, L, Feng, W, Wang, C.-C.
登録日2011-10-30
公開日2011-11-23
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Human protein-disulfide isomerase is a redox-regulated chaperone activated by oxidation of domain a'
J.Biol.Chem., 287, 2012
8EKY
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BU of 8eky by Molmil
Cryo-EM structure of the human PRDX4-ErP46 complex
分子名称: Peroxiredoxin-4, Thioredoxin domain-containing protein 5
著者Su, C.C.
登録日2022-09-22
公開日2023-05-03
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献High-resolution structural-omics of human liver enzymes.
Cell Rep, 42, 2023
8EOJ
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BU of 8eoj by Molmil
Microsomal triglyceride transfer protein
分子名称: Microsomal triglyceride transfer protein large subunit, Protein disulfide-isomerase
著者Zhang, Z.
登録日2022-10-03
公開日2023-05-03
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献High-resolution structural-omics of human liver enzymes.
Cell Rep, 42, 2023
7P9D
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BU of 7p9d by Molmil
Crystal structure of Chlamydomonas reinhardtii NADPH Dependent Thioredoxin Reductase 1 domain
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Thioredoxin reductase
著者Singh, R.K, Marchetti, G.M, Hippler, M, Kuemmel, D.
登録日2021-07-27
公開日2022-01-12
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structural analysis revealed a novel conformation of the NTRC reductase domain from Chlamydomonas reinhardtii.
J.Struct.Biol., 214, 2021
7P9E
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BU of 7p9e by Molmil
Chlamydomonas reinhardtii NADPH Dependent Thioredoxin Reductase 1 domain CS mutant
分子名称: 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, FLAVIN-ADENINE DINUCLEOTIDE, Thioredoxin reductase
著者Fuesser, F, Kuemmel, D.
登録日2021-07-27
公開日2022-01-19
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Structural analysis revealed a novel conformation of the NTRC reductase domain from Chlamydomonas reinhardtii.
J.Struct.Biol., 214, 2021
4DSS
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BU of 4dss by Molmil
Crystal structure of peroxiredoxin Ahp1 from Saccharomyces cerevisiae in complex with thioredoxin Trx2
分子名称: Peroxiredoxin type-2, Thioredoxin-2
著者Lian, F.M, Yu, J, Ma, X.X, Yu, X.J, Chen, Y, Zhou, C.Z.
登録日2012-02-19
公開日2012-04-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Snapshots of Yeast Alkyl Hydroperoxide Reductase Ahp1 Peroxiredoxin Reveal a Novel Two-cysteine Mechanism of Electron Transfer to Eliminate Reactive Oxygen Species.
J.Biol.Chem., 287, 2012
3APQ
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BU of 3apq by Molmil
Crystal structure of J-Trx1 fragment of ERdj5
分子名称: DnaJ homolog subfamily C member 10
著者Inaba, K, Suzuki, M, Nagata, K.
登録日2010-10-20
公開日2011-04-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Structural basis of an ERAD pathway mediated by the ER-resident protein disulfide reductase ERdj5.
Mol.Cell, 41, 2011
7QNG
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BU of 7qng by Molmil
Structure of a MHC I-Tapasin-ERp57 complex
分子名称: Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ...
著者Mueller, I.K, Thomas, C, Trowitzsch, S, Tampe, R.
登録日2021-12-20
公開日2022-09-28
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of an MHC I-tapasin-ERp57 editing complex defines chaperone promiscuity.
Nat Commun, 13, 2022
7QPD
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BU of 7qpd by Molmil
Structure of the human MHC I peptide-loading complex editing module
分子名称: Beta-2-microglobulin, Calreticulin, HLA class I histocompatibility antigen, ...
著者Domnick, A, Susac, L, Trowitzsch, S, Thomas, C, Tampe, R.
登録日2022-01-03
公開日2022-07-20
最終更新日2022-08-24
実験手法ELECTRON MICROSCOPY (3.73 Å)
主引用文献Molecular basis of MHC I quality control in the peptide loading complex.
Nat Commun, 13, 2022
3P2A
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BU of 3p2a by Molmil
Crystal Structure of Thioredoxin 2 from Yersinia pestis
分子名称: FORMIC ACID, Putative thioredoxin-like protein, ZINC ION
著者Kim, Y, Zhou, M, Grimshaw, S, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2010-10-01
公開日2010-10-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.195 Å)
主引用文献Crystal Structure of Thioredoxin 2 from Yersinia pestis
TO BE PUBLISHED
3BOA
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BU of 3boa by Molmil
Crystal structure of yeast protein disulfide isomerase.
分子名称: Protein disulfide-isomerase
著者Tian, G, Lennarz, W.J, Schindelin, H.
登録日2007-12-17
公開日2008-09-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献The Catalytic Activity of Protein-disulfide Isomerase Requires a Conformationally Flexible Molecule.
J.Biol.Chem., 283, 2008
3APO
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BU of 3apo by Molmil
Crystal structure of full-length ERdj5
分子名称: DnaJ homolog subfamily C member 10
著者Inaba, K, Suzuki, M, Nagata, K.
登録日2010-10-20
公開日2011-04-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis of an ERAD pathway mediated by the ER-resident protein disulfide reductase ERdj5.
Mol.Cell, 41, 2011
4EL1
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BU of 4el1 by Molmil
Crystal structure of oxidized hPDI (abb'xa')
分子名称: Protein disulfide-isomerase
著者Wang, C, Li, W, Ren, J, Ke, H, Gong, W, Feng, W, Wang, C.-C.
登録日2012-04-10
公開日2013-04-10
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.883 Å)
主引用文献Structural insights into the redox-regulated dynamic conformations of human protein disulfide isomerase
Antioxid Redox Signal, 19, 2013
4EKZ
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BU of 4ekz by Molmil
Crystal structure of reduced hPDI (abb'xa')
分子名称: Protein disulfide-isomerase
著者Wang, C, Li, W, Ren, J, Ke, H, Gong, W, Feng, W, Wang, C.-C.
登録日2012-04-10
公開日2013-04-10
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Structural insights into the redox-regulated dynamic conformations of human protein disulfide isomerase
Antioxid Redox Signal, 19, 2013
5XF7
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BU of 5xf7 by Molmil
Crystal structure of human protein disulfide isomerase-like protein of the testis
分子名称: Protein disulfide-isomerase-like protein of the testis
著者Li, H, Li, J, Liu, Y, Liang, H.
登録日2017-04-08
公開日2017-12-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.381 Å)
主引用文献Crystal and solution structures of human protein-disulfide isomerase-like protein of the testis (PDILT) provide insight into its chaperone activity
J. Biol. Chem., 293, 2018
5HQP
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BU of 5hqp by Molmil
Crystal structure of the ERp44-peroxiredoxin 4 complex
分子名称: Endoplasmic reticulum resident protein 44, Peroxiredoxin-4
著者Yang, K, Li, D.F, Wang, X, Wang, C.C.
登録日2016-01-22
公開日2016-10-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of the ERp44-Peroxiredoxin 4 Complex Reveals the Molecular Mechanisms of Thiol-Mediated Protein Retention.
Structure, 24, 2016
5XWM
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BU of 5xwm by Molmil
human ERp44 zinc-bound form
分子名称: CHLORIDE ION, Endoplasmic reticulum resident protein 44, ZINC ION
著者Watanabe, S, Harayama, M, Inaba, K.
登録日2017-06-30
公開日2019-01-02
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Zinc regulates ERp44-dependent protein quality control in the early secretory pathway.
Nat Commun, 10, 2019
5IKN
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BU of 5ikn by Molmil
Crystal Structure of the T7 Replisome in the Absence of DNA
分子名称: DNA primase/helicase, DNA-directed DNA polymerase, Thioredoxin-1
著者Wallen, J.R, Ellenberger, T.
登録日2016-03-03
公開日2016-12-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (4.802 Å)
主引用文献Hybrid Methods Reveal Multiple Flexibly Linked DNA Polymerases within the Bacteriophage T7 Replisome.
Structure, 25, 2017
7BVV
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BU of 7bvv by Molmil
Crystal structure of sulfonic peroxiredoxin Ahp1 in complex with thioredoxin Trx2
分子名称: Peroxiredoxin AHP1, Thioredoxin-2
著者Lian, F.M, Jiang, Y.L, Yang, W, Yang, X.
登録日2020-04-11
公開日2020-07-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Crystal structure of sulfonic peroxiredoxin Ahp1 in complex with thioredoxin Trx2 mimics a conformational intermediate during the catalytic cycle.
Int.J.Biol.Macromol., 161, 2020
6ZYW
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BU of 6zyw by Molmil
Outer Dynein Arm-Shulin complex - overall structure (Tetrahymena thermophila)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Dynein heavy chain, ...
著者Mali, G.R, Abid Ali, F, Lau, C.K, Carter, A.P.
登録日2020-08-03
公開日2021-01-20
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (8.78 Å)
主引用文献Shulin packages axonemal outer dynein arms for ciliary targeting.
Science, 371, 2021
7BZK
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BU of 7bzk by Molmil
Crystal structure of ferredoxin: thioredoxin reductase and thioredoxin y1 complex
分子名称: Ferredoxin-thioredoxin reductase catalytic chain, chloroplastic, IRON/SULFUR CLUSTER, ...
著者Kurisu, G, Juniar, L, Tanaka, H.
登録日2020-04-28
公開日2020-10-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.5935 Å)
主引用文献Structural basis for thioredoxin isoform-based fine-tuning of ferredoxin-thioredoxin reductase activity.
Protein Sci., 29, 2020
5XOC
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BU of 5xoc by Molmil
Crystal structure of human Smad3-FoxH1 complex
分子名称: Mothers against decapentaplegic homolog 3, Thioredoxin 1,Forkhead box protein H1
著者Miyazono, K, Ito, T, Tanokura, M.
登録日2017-05-27
公開日2018-03-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Hydrophobic patches on SMAD2 and SMAD3 determine selective binding to cofactors
Sci Signal, 11, 2018
6N7W
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BU of 6n7w by Molmil
Structure of bacteriophage T7 leading-strand DNA polymerase (D5A/E7A)/Trx in complex with a DNA fork and incoming dTTP (from multiple lead complexes)
分子名称: DNA (25-MER), DNA (77-MER), DNA-directed DNA polymerase, ...
著者Gao, Y, Fox, T, Val, N, Yang, W.
登録日2018-11-28
公開日2019-03-06
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structures and operating principles of the replisome.
Science, 363, 2019
5E4W
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BU of 5e4w by Molmil
Crystal structure of cpSRP43 chromodomains 2 and 3 in complex with the Alb3 tail
分子名称: CALCIUM ION, GLYCEROL, Inner membrane protein ALBINO3, ...
著者Horn, A, Ahmed, Y.L, Wild, K, Sinning, I.
登録日2015-10-07
公開日2015-12-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for cpSRP43 chromodomain selectivity and dynamics in Alb3 insertase interaction.
Nat Commun, 6, 2015

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