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8OSZ
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Structural and functional studies of geldanamycin amide synthase ShGdmF
分子名称: 3-aminophenol, ACETATE ION, DI(HYDROXYETHYL)ETHER, ...
著者Ewert, W, Zeilinger, C, Kirschning, A, Preller, M.
登録日2023-04-20
公開日2024-05-01
実験手法X-RAY DIFFRACTION (1.26 Å)
主引用文献Structural and functional studies of geldanamycin amide synthase ShGdmF
To Be Published
8OSV
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BU of 8osv by Molmil
Structural and functional studies of geldanamycin amide synthase ShGdmF
分子名称: 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ...
著者Ewert, W, Zeilinger, C, Kirschning, A, Preller, M.
登録日2023-04-20
公開日2024-05-01
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献Structural and functional studies of geldanamycin amide synthase ShGdmF
To Be Published
8OSL
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BU of 8osl by Molmil
Cryo-EM structure of CLOCK-BMAL1 bound to the native Por enhancer nucleosome (map 2, additional 3D classification and flexible refinement)
分子名称: Basic helix-loop-helix ARNT-like protein 1, Circadian locomoter output cycles protein kaput, DNA (147-MER), ...
著者Michael, A.K, Stoos, L, Kempf, G, Cavadini, S, Thoma, N.
登録日2023-04-19
公開日2023-05-24
最終更新日2023-07-26
実験手法ELECTRON MICROSCOPY (4.9 Å)
主引用文献Cooperation between bHLH transcription factors and histones for DNA access.
Nature, 619, 2023
8OSK
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BU of 8osk by Molmil
Cryo-EM structure of CLOCK-BMAL1 bound to a nucleosomal E-box at position SHL+5.8 (composite map)
分子名称: Basic helix-loop-helix ARNT-like protein 1, Circadian locomoter output cycles protein kaput, DNA (124-MER), ...
著者Stoos, L, Michael, A.K, Kempf, G, Cavadini, S, Thoma, N.H.
登録日2023-04-19
公開日2023-05-24
最終更新日2023-07-26
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cooperation between bHLH transcription factors and histones for DNA access.
Nature, 619, 2023
8OSJ
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BU of 8osj by Molmil
Cryo-EM structure of CLOCK-BMAL1 bound to a nucleosomal E-box at position SHL-6.2 (DNA conformation 1)
分子名称: Basic helix-loop-helix ARNT-like protein 1, Circadian locomoter output cycles protein kaput, DNA (124-MER), ...
著者Michael, A.K, Stoos, L, Kempf, G, Cavadini, S, Thoma, N.H.
登録日2023-04-19
公開日2023-05-24
最終更新日2023-07-26
実験手法ELECTRON MICROSCOPY (6.2 Å)
主引用文献Cooperation between bHLH transcription factors and histones for DNA access.
Nature, 619, 2023
8OQL
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BU of 8oql by Molmil
Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with Fragment-M-1
分子名称: 3-hydroxyacyl-CoA dehydrogenase, FORMAMIDE, GLYCEROL, ...
著者Dalwani, S, Wierenga, R.K, Venkatesan, R.
登録日2023-04-12
公開日2024-01-24
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystallographic fragment binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate channeling path between them
Biorxiv, 2024
8OPR
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BU of 8opr by Molmil
Structure of the EA1 surface layer of Bacillus anthracis
分子名称: ACETATE ION, CALCIUM ION, Nanobody 632, ...
著者Sogues, A, Remaut, H.
登録日2023-04-07
公開日2023-11-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.811 Å)
主引用文献Structure and function of the EA1 surface layer of Bacillus anthracis.
Nat Commun, 14, 2023
8OOT
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BU of 8oot by Molmil
CryoEM Structure INO80core Hexasome complex Arp5 Ies6 refinement state2
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 5, Chromatin-remodeling complex subunit IES6, ...
著者Zhang, M, Jungblut, A, Hoffmann, T, Eustermann, S.
登録日2023-04-05
公開日2023-07-26
最終更新日2023-08-02
実験手法ELECTRON MICROSCOPY (2.85 Å)
主引用文献Hexasome-INO80 complex reveals structural basis of noncanonical nucleosome remodeling.
Science, 381, 2023
8OOS
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BU of 8oos by Molmil
CryoEM Structure INO80core Hexasome complex ATPase-hexasome refinement state 2
分子名称: ADENOSINE-5'-DIPHOSPHATE, Chromatin-remodeling ATPase Ino80, DNA Strand 2, ...
著者Zhang, M, Jungblut, A, Hoffmann, T, Eustermann, S.
登録日2023-04-05
公開日2023-07-26
最終更新日2023-08-02
実験手法ELECTRON MICROSCOPY (3.29 Å)
主引用文献Hexasome-INO80 complex reveals structural basis of noncanonical nucleosome remodeling.
Science, 381, 2023
8OOR
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BU of 8oor by Molmil
CryoEM Structure INO80core Hexasome complex Rvb core refinement state2
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 5, ...
著者Zhang, M, Jungblut, A, Hoffmann, T, Eustermann, S.
登録日2023-04-05
公開日2023-07-26
最終更新日2023-08-02
実験手法ELECTRON MICROSCOPY (2.87 Å)
主引用文献Hexasome-INO80 complex reveals structural basis of noncanonical nucleosome remodeling.
Science, 381, 2023
8OOP
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BU of 8oop by Molmil
CryoEM Structure INO80core Hexasome complex composite model state2
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 5, ...
著者Zhang, M, Jungblut, A, Hoffmann, T, Eustermann, S.
登録日2023-04-05
公開日2023-07-26
最終更新日2023-08-02
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Hexasome-INO80 complex reveals structural basis of noncanonical nucleosome remodeling.
Science, 381, 2023
8OOM
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BU of 8oom by Molmil
Structural and functional studies of geldanamycin amide synthase ShGdmF
分子名称: (2R)-2,4-dihydroxy-3,3-dimethyl-N-{3-oxo-3-[(2-sulfanylethyl)amino]propyl}butanamide, ACETATE ION, GdmF
著者Ewert, W, Zeilinger, C, Kirschning, A, Preller, M.
登録日2023-04-05
公開日2024-04-17
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Structural and functional studies of geldanamycin amide synthase ShGdmF
To Be Published
8OOK
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BU of 8ook by Molmil
CryoEM Structure INO80core Hexasome complex Arp5 grappler refinement state1
分子名称: Actin-related protein 5
著者Zhang, M, Jungblut, A, Hoffmann, T, Eustermann, S.
登録日2023-04-05
公開日2023-07-26
最終更新日2023-08-02
実験手法ELECTRON MICROSCOPY (5.69 Å)
主引用文献Hexasome-INO80 complex reveals structural basis of noncanonical nucleosome remodeling.
Science, 381, 2023
8OOF
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BU of 8oof by Molmil
CryoEM Structure INO80core Hexasome complex Arp5 Ies6 refinement state1
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 5, Chromatin-remodeling complex subunit IES6, ...
著者Zhang, M, Jungblut, A, Hoffmann, T, Eustermann, S.
登録日2023-04-05
公開日2023-07-26
最終更新日2023-08-02
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Hexasome-INO80 complex reveals structural basis of noncanonical nucleosome remodeling.
Science, 381, 2023
8OOD
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BU of 8ood by Molmil
Crystal structure of human DCAF1 WD40 repeats (Q1250L) in complex with compound 15
分子名称: 1,2-ETHANEDIOL, ACETATE ION, DDB1- and CUL4-associated factor 1, ...
著者Schroeder, M, Renatus, M.
登録日2023-04-05
公開日2023-05-24
実験手法X-RAY DIFFRACTION (1.497 Å)
主引用文献Reinstating targeted protein degradation with DCAF1 PROTACs in CRBN PROTAC resistant settings
Biorxiv, 2023
8OOC
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BU of 8ooc by Molmil
CryoEM Structure INO80core Hexasome complex Rvb core refinement state1
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Chromatin-remodeling ATPase Ino80, ...
著者Zhang, M, Jungblut, A, Hoffmann, T, Eustermann, S.
登録日2023-04-05
公開日2023-08-02
実験手法ELECTRON MICROSCOPY (2.93 Å)
主引用文献Hexasome-INO80 complex reveals structural basis of noncanonical nucleosome remodeling.
Science, 381, 2023
8OOA
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BU of 8ooa by Molmil
CryoEM Structure INO80core Hexasome complex Hexasome refinement state1
分子名称: DNA Strand 2, DNA strand 1, Histone H2A, ...
著者Zhang, M, Jungblut, A, Hoffmann, T, Eustermann, S.
登録日2023-04-04
公開日2023-07-26
最終更新日2023-08-02
実験手法ELECTRON MICROSCOPY (3.18 Å)
主引用文献Hexasome-INO80 complex reveals structural basis of noncanonical nucleosome remodeling.
Science, 381, 2023
8OO9
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BU of 8oo9 by Molmil
CryoEM Structure INO80core Hexasome complex ATPase-DNA refinement state1
分子名称: ADENOSINE-5'-DIPHOSPHATE, Chromatin-remodeling ATPase INO80, DNA strand 1, ...
著者Zhang, M, Jungblut, A, Hoffmann, T, Eustermann, S.
登録日2023-04-04
公開日2023-07-26
最終更新日2023-08-02
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Hexasome-INO80 complex reveals structural basis of noncanonical nucleosome remodeling.
Science, 381, 2023
8OO7
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BU of 8oo7 by Molmil
CryoEM Structure INO80core Hexasome complex composite model state1
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 5, ...
著者Zhang, M, Jungblut, A, Hoffmann, T, Eustermann, S.
登録日2023-04-04
公開日2023-07-26
最終更新日2023-08-02
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Hexasome-INO80 complex reveals structural basis of noncanonical nucleosome remodeling.
Science, 381, 2023
8OO4
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BU of 8oo4 by Molmil
X-ray structure of the adduct formed upon reaction of cisplatin with human angiogenin after 1 month soaking
分子名称: AMMONIA, Angiogenin, PLATINUM (II) ION
著者Ferraro, G, Merlino, A.
登録日2023-04-04
公開日2023-07-12
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Cisplatin binding to angiogenin protein: new molecular pathways and targets for the drug's anticancer activity.
Dalton Trans, 52, 2023
8OO3
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BU of 8oo3 by Molmil
X-ray structure of the adduct formed upon reaction of cisplatin with human angiogenin after 5 days soaking
分子名称: AMMONIA, Angiogenin, D(-)-TARTARIC ACID, ...
著者Ferraro, G, Merlino, A.
登録日2023-04-04
公開日2023-07-12
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Cisplatin binding to angiogenin protein: new molecular pathways and targets for the drug's anticancer activity.
Dalton Trans, 52, 2023
8OMI
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BU of 8omi by Molmil
Crystal structure of the inositol hexakisphosphate kinase EhIP6KA M85 variant in complex with ATP and Mg2+
分子名称: 1,2-ETHANEDIOL, ACETATE ION, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Schuetz, A, Aguirre, T, Fiedler, D.
登録日2023-03-31
公開日2024-01-10
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献An unconventional gatekeeper mutation sensitizes inositol hexakisphosphate kinases to an allosteric inhibitor.
Elife, 12, 2023
8OM8
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BU of 8om8 by Molmil
X-ray structure of lysozyme obtained upon reaction with [VIVO(empp)2] (Structure A)
分子名称: 1-methyl-2-ethyl-3-hydroxy-4(1H)-pyridinone)V(IV)O4, ACETATE ION, CHLORIDE ION, ...
著者Paolillo, M, Ferraro, G, Merlino, A.
登録日2023-03-31
公開日2023-06-07
実験手法X-RAY DIFFRACTION (1.08 Å)
主引用文献Implications of Protein Interaction in the Speciation of Potential V IV O-Pyridinone Drugs.
Inorg.Chem., 62, 2023
8OL1
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BU of 8ol1 by Molmil
cGAS-Nucleosome in complex with SPSB3-ELOBC (composite structure)
分子名称: Cyclic GMP-AMP synthase, DNA (145-MER), Elongin-B, ...
著者Xu, P.B, Ablasser, A.
登録日2023-03-29
公開日2024-02-14
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献The CRL5-SPSB3 ubiquitin ligase targets nuclear cGAS for degradation.
Nature, 627, 2024
8OKK
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BU of 8okk by Molmil
Crystal structure of F2F-2020184-00X bound to the main protease (3CLpro/Mpro) of SARS-CoV-2.
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 3C-like proteinase nsp5, ...
著者Costanzi, E, Demitri, N, Storici, P.
登録日2023-03-28
公開日2023-05-03
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Broad-spectrum coronavirus 3C-like protease peptidomimetic inhibitors effectively block SARS-CoV-2 replication in cells: Design, synthesis, biological evaluation, and X-ray structure determination.
Eur.J.Med.Chem., 253, 2023

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件を2024-06-12に公開中

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