8OO3

X-ray structure of the adduct formed upon reaction of cisplatin with human angiogenin after 5 days soaking

This is a non-PDB format compatible entry.

Summary for 8OO3

• Entry DOI: 10.2210/pdb8oo3/pdb
• Descriptor: Angiogenin, GLYCEROL, AMMONIA, ... (6 entities in total)
• Functional Keywords: angiogenin, cddp, ros production, prostate cancer, hydrolase
• Biological source: Homo sapiens
• Total number of polymer chains: 1
• Total formula weight: 14623.33

Authors

Ferraro, G.,Merlino, A. (deposition date: 2023-04-04, release date: 2023-07-12, Last modification date: 2024-01-24)

• Primary citation: Ferraro, G.,Sanfilippo, V.,Chiaverini, L.,Satriano, C.,Marzo, T.,Merlino, A.,La Mendola, D.; Cisplatin binding to angiogenin protein: new molecular pathways and targets for the drug's anticancer activity.; Dalton Trans, 52:9058-9067, 2023; PubMed: 37337706; DOI: 10.1039/d3dt01517c

Experimental method

X-RAY DIFFRACTION (1.76 Å)