8Q2Z
 
 | | HsNMT1 in complex with both MyrCoA and GNLLSKFR peptide | | 分子名称: | CHLORIDE ION, COENZYME A, GLYCEROL, ... | | 著者 | Dian, C, Giglione, C, Meinnel, T. | | 登録日 | 2023-08-03 | | 公開日 | 2024-08-14 | | 最終更新日 | 2025-02-26 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | Novel, tightly structurally related N-myristoyltransferase inhibitors display equally potent yet distinct inhibitory mechanisms.
Structure, 32, 2024
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8Q24
 | | HsNMT1 in complex with both MyrCoA and (DAB)SFSKPR inhibitor peptide | | 分子名称: | CHLORIDE ION, DAB-SER-PHE-SER-LYS-PRO-ARG, GLYCEROL, ... | | 著者 | Dian, C, Giglione, C, Meinnel, T. | | 登録日 | 2023-08-01 | | 公開日 | 2024-08-14 | | 最終更新日 | 2025-02-26 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Novel, tightly structurally related N-myristoyltransferase inhibitors display equally potent yet distinct inhibitory mechanisms.
Structure, 32, 2024
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2JLM
 | | Structure of a Putative Acetyltransferase (ACIAD1637) from Acinetobacter baylyi ADP1 | | 分子名称: | ACETATE ION, AZIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Davies, A.M, Tata, R, Snape, A, Sutton, B.J, Brown, P.R. | | 登録日 | 2008-09-10 | | 公開日 | 2009-01-20 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structure and Substrate Specificity of Acetyltransferase Aciad1637 from Acinetobacter Baylyi Adp1.
Biochimie, 91, 2009
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2JDD
 | | Glyphosate N-acetyltransferase bound to acetyl COA and 3-phosphoglycerate | | 分子名称: | 3-PHOSPHOGLYCERIC ACID, ACETYL COENZYME *A, GLYPHOSATE N-ACETYLTRANSFERASE, ... | | 著者 | Siehl, D.L, Castle, L.A, Gorton, R, Keenan, R.J. | | 登録日 | 2007-01-06 | | 公開日 | 2007-02-13 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The molecular basis of glyphosate resistance by an optimized microbial acetyltransferase.
J. Biol. Chem., 282, 2007
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2JDC
 | | Glyphosate N-acetyltransferase bound to oxidized COA and sulfate | | 分子名称: | GLYPHOSATE N-ACETYLTRANSFERASE, OXIDIZED COENZYME A, SULFATE ION | | 著者 | Siehl, D.L, Castle, L.A, Gorton, R, Keenan, R.J. | | 登録日 | 2007-01-05 | | 公開日 | 2007-02-13 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The Molecular Basis of Glyphosate Resistance by an Optimized Microbial Acetyltransferase.
J.Biol.Chem., 282, 2007
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7OWQ
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7OWN
 | | HsNMT1 in complex with both MyrCoA and peptide AKSFSKPR | | 分子名称: | ALA-LYS-SER-PHE-SER-LYS-PRO-ARG, GLYCEROL, Glycylpeptide N-tetradecanoyltransferase 1, ... | | 著者 | Dian, C, Giglione, C, Meinnel, T. | | 登録日 | 2021-06-18 | | 公開日 | 2022-12-21 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural and Large-scale Analysis Unveil the Intertwined Paths Promoting NMT-catalyzed Lysine and Glycine Myristoylation.
J.Mol.Biol., 434, 2022
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7OWU
 | | HsNMT1 in complex with both CoA and Myr-ANCFSKPR peptide | | 分子名称: | ALA-ASN-CYS-PHE-SER-LYS-PRO-ARG, COENZYME A, GLYCEROL, ... | | 著者 | Dian, C, Giglione, C, Meinnel, T. | | 登録日 | 2021-06-18 | | 公開日 | 2022-12-21 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | Structural and Large-scale Analysis Unveil the Intertwined Paths Promoting NMT-catalyzed Lysine and Glycine Myristoylation.
J.Mol.Biol., 434, 2022
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7OWO
 | | HsNMT1 in complex with both MyrCoA and N-acetylated KSFSKPR peptide | | 分子名称: | COENZYME A, GLYCEROL, Glycylpeptide N-tetradecanoyltransferase 1, ... | | 著者 | Dian, C, Giglione, C, Meinnel, T. | | 登録日 | 2021-06-18 | | 公開日 | 2022-12-21 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural and Large-scale Analysis Unveil the Intertwined Paths Promoting NMT-catalyzed Lysine and Glycine Myristoylation.
J.Mol.Biol., 434, 2022
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7OWM
 | | HsNMT1 in complex with both MyrCoA and HCPA substrate peptide GKQNSKLR | | 分子名称: | GLYCEROL, Glycylpeptide N-tetradecanoyltransferase 1, Neuron-specific calcium-binding protein hippocalcin, ... | | 著者 | Dian, C, Giglione, C, Meinnel, T. | | 登録日 | 2021-06-18 | | 公開日 | 2022-12-21 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural and Large-scale Analysis Unveil the Intertwined Paths Promoting NMT-catalyzed Lysine and Glycine Myristoylation.
J.Mol.Biol., 434, 2022
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7OWP
 | | HsNMT1 in complex with both MyrCoA and ACE-G-(L-ORN)SFSKPR | | 分子名称: | ACE-GLY-ORN-SER-PHE-SER-LYS-PRO-ARG, GLYCEROL, Glycylpeptide N-tetradecanoyltransferase 1, ... | | 著者 | Dian, C, Giglione, C, Meinnel, T. | | 登録日 | 2021-06-18 | | 公開日 | 2022-12-21 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Structural and Large-scale Analysis Unveil the Intertwined Paths Promoting NMT-catalyzed Lysine and Glycine Myristoylation.
J.Mol.Biol., 434, 2022
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7OWR
 | | HsNMT1 in complex with both MyrCoA and peptide GGKSFSKPR | | 分子名称: | GLY-GLY-LYS-SER-PHE-SER-LYS-PRO-ARG, GLYCEROL, Glycylpeptide N-tetradecanoyltransferase 1, ... | | 著者 | Dian, C, Giglione, C, Meinnel, T. | | 登録日 | 2021-06-18 | | 公開日 | 2022-12-21 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | Structural and Large-scale Analysis Unveil the Intertwined Paths Promoting NMT-catalyzed Lysine and Glycine Myristoylation.
J.Mol.Biol., 434, 2022
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2YGW
 | | Crystal structure of human MCD | | 分子名称: | 1,2-ETHANEDIOL, MALONYL-COA DECARBOXYLASE, MITOCHONDRIAL, ... | | 著者 | Vollmar, M, Puranik, S, Krojer, T, Savitsky, P, Allerston, C, Yue, W.W, Chaikuad, A, von Delft, F, Gileadi, O, Kavanagh, K, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, Oppermann, U. | | 登録日 | 2011-04-21 | | 公開日 | 2012-02-15 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal Structures of Malonyl-Coenzyme a Decarboxylase Provide Insights Into its Catalytic Mechanism and Disease-Causing Mutations.
Structure, 21, 2013
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2IL4
 | | Crystal structure of At1g77540-Coenzyme A Complex | | 分子名称: | COENZYME A, Protein At1g77540 | | 著者 | Bitto, E, Wesenberg, G.E, Phillips Jr, G.N, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG) | | 登録日 | 2006-10-02 | | 公開日 | 2006-10-17 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.054 Å) | | 主引用文献 | Structure of Arabidopsis thaliana At1g77540 Protein, a Minimal Acetyltransferase from the COG2388 Family.
Biochemistry, 45, 2006
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8WMB
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8WME
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3W91
 | | crystal structure of SeMet-labeled yeast N-acetyltransferase Mpr1 L87M mutant | | 分子名称: | MPR1 protein | | 著者 | Nasuno, R, Hirano, Y, Itoh, T, Hakoshima, T, Hibi, T, Takagi, H. | | 登録日 | 2013-03-23 | | 公開日 | 2013-07-17 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural and functional analysis of the yeast N-acetyltransferase Mpr1 involved in oxidative stress tolerance via proline metabolism
Proc.Natl.Acad.Sci.USA, 110, 2013
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2AE6
 | | Crystal Structure of Acetyltransferase of GNAT family from Enterococcus faecalis V583 | | 分子名称: | ETHANOL, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Kim, Y, Hatzos, C, Moy, S, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2005-07-21 | | 公開日 | 2005-09-06 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Crystal Structure of Acetyltransferase of GNAT family from Enterococcus faecalis V583
To be Published
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3W6X
 | | Yeast N-acetyltransferase Mpr1 in complex with CHOP | | 分子名称: | (4S)-4-hydroxy-L-proline, CHLORIDE ION, HEXAETHYLENE GLYCOL, ... | | 著者 | Nasuno, R, Hirano, Y, Itoh, T, Hakoshima, T, Hibi, T, Takagi, H. | | 登録日 | 2013-02-25 | | 公開日 | 2013-08-07 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.299 Å) | | 主引用文献 | Structural and functional analysis of the yeast N-acetyltransferase Mpr1 involved in oxidative stress tolerance via proline metabolism
Proc.Natl.Acad.Sci.USA, 110, 2013
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3W6S
 | | yeast N-acetyltransferase Mpr1 involved in oxidative stress tolerance via proline metabolism | | 分子名称: | HEXAETHYLENE GLYCOL, MAGNESIUM ION, MPR1 protein | | 著者 | Nasuno, R, Hirano, Y, Itoh, T, Hakoshima, T, Hibi, T, Takagi, H. | | 登録日 | 2013-02-21 | | 公開日 | 2013-07-17 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural and functional analysis of the yeast N-acetyltransferase Mpr1 involved in oxidative stress tolerance via proline metabolism
Proc.Natl.Acad.Sci.USA, 110, 2013
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2CXA
 | | Crystal structure of Leucyl/phenylalanyl-tRNA protein transferase from Escherichia coli | | 分子名称: | Leucyl/phenylalanyl-tRNA-protein transferase | | 著者 | Kato-Murayama, M, Bessho, Y, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-06-28 | | 公開日 | 2005-12-28 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The crystal structure of leucyl/phenylalanyl-tRNA-protein transferase from Escherichia coli
Protein Sci., 16, 2007
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4AVA
 | | Crystal structure of protein lysine acetyltransferase Rv0998 from Mycobacterium tuberculosis | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, ACETYL COENZYME *A, ... | | 著者 | Lee, H.J, Lang, P.T, Fortune, S.M, Sassetti, C.M, Alber, T. | | 登録日 | 2012-05-24 | | 公開日 | 2012-07-11 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.698 Å) | | 主引用文献 | Cyclic AMP Regulation of Protein Lysine Acetylation in Mycobacterium Tuberculosis.
Nat.Struct.Mol.Biol., 19, 2012
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4FD6
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4FD4
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4AVB
 | | Crystal structure of protein lysine acetyltransferase Rv0998 in complex with acetyl CoA and cAMP | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, ACETYL COENZYME *A, ... | | 著者 | Lee, H.J, Lang, P.T, Fortune, S.M, Sassetti, C.M, Alber, T. | | 登録日 | 2012-05-24 | | 公開日 | 2012-07-11 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Cyclic AMP Regulation of Protein Lysine Acetylation in Mycobacterium Tuberculosis.
Nat.Struct.Mol.Biol., 19, 2012
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