4BJ9
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![BU of 4bj9 by Molmil](/molmil-images/mine/4bj9) | Crystal structure of human tankyrase 2 in complex with EB-47 | 分子名称: | 2-[4-[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]carbonylpiperazin-1-yl]-N-(1-oxidanylidene-2,3-dihydroisoindol-4-yl)ethanamide, GLYCEROL, SULFATE ION, ... | 著者 | Haikarainen, T, Narwal, M, Lehtio, L. | 登録日 | 2013-04-17 | 公開日 | 2013-12-11 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Evaluation and Structural Basis for the Inhibition of Tankyrases by Parp Inhibitors Acs Med.Chem.Lett., 5, 2014
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4BGK
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![BU of 4bgk by Molmil](/molmil-images/mine/4bgk) | Three dimensional structure of human gamma-butyrobetaine hydroxylase in complex with (3-(Trimethylammonio)propyl)phosphinate | 分子名称: | GAMMA-BUTYROBETAINE DIOXYGENASE, HEXANE-1,6-DIAMINE, N-OXALYLGLYCINE, ... | 著者 | Tars, K, Leitans, J, Kazaks, A. | 登録日 | 2013-03-27 | 公開日 | 2014-03-12 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Targeting Carnitine Biosynthesis: Discovery of New Inhibitors Against Gamma-Butyrobetaine Hydroxylase. J.Med.Chem., 57, 2014
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2A8W
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![BU of 2a8w by Molmil](/molmil-images/mine/2a8w) | Crystal Structure of Human N-acetylgalactosaminyltransferase (GTA) Complexed with Beta-Methyllactoside | 分子名称: | CHLORIDE ION, Histo-blood group ABO system transferase (NAGAT) [Includes: Glycoprotein-fucosylgalactoside alpha-N- acetylgalactosaminyltransferase (EC 2.4.1.40) (Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase) (Histo-blood group A transferase) (A transferase); Glycoprotein-fucosylgalactoside alpha- galactosyltransferase (EC 2.4.1.37) (Fucosylglycoprotein 3-alpha- galactosyltransferase) (Histo-blood group B transferase) (B transferase)] [Contains: Fucosylglycoprotein alpha-N- acetylgalactosaminyltransferase, soluble form], ... | 著者 | Letts, J.A, Rose, N.L, Fang, Y.R, Barry, C.H, Borisova, S.N, Seto, N.O, Palcic, M.M, Evans, S.V. | 登録日 | 2005-07-09 | 公開日 | 2005-12-13 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | Differential Recognition of the Type I and II H Antigen Acceptors by the Human ABO(H) Blood Group A and B Glycosyltransferases. J.Biol.Chem., 281, 2006
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2DBV
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![BU of 2dbv by Molmil](/molmil-images/mine/2dbv) | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE MUTANT WITH ASP 32 REPLACED BY GLY, LEU 187 REPLACED BY ALA, AND PRO 188 REPLACED BY SER COMPLEXED WITH NADP+ | 分子名称: | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION | 著者 | Didierjean, C, Rahuel-Clermont, S, Vitoux, B, Dideberg, O, Branlant, G, Aubry, A. | 登録日 | 1996-12-19 | 公開日 | 1997-07-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | A crystallographic comparison between mutated glyceraldehyde-3-phosphate dehydrogenases from Bacillus stearothermophilus complexed with either NAD+ or NADP+. J.Mol.Biol., 268, 1997
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2DAP
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![BU of 2dap by Molmil](/molmil-images/mine/2dap) | C. GLUTAMICUM DAP DEHYDROGENASE IN COMPLEX WITH DAP | 分子名称: | 2,6-DIAMINOPIMELIC ACID, DIAMINOPIMELIC ACID DEHYDROGENASE | 著者 | Scapin, G, Cirilli, M, Reddy, S.G, Gao, Y, Vederas, J.C, Blanchard, J.S. | 登録日 | 1997-12-23 | 公開日 | 1998-04-08 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Substrate and inhibitor binding sites in Corynebacterium glutamicum diaminopimelate dehydrogenase. Biochemistry, 37, 1998
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2E00
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![BU of 2e00 by Molmil](/molmil-images/mine/2e00) | |
2E2K
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![BU of 2e2k by Molmil](/molmil-images/mine/2e2k) | |
2E0C
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![BU of 2e0c by Molmil](/molmil-images/mine/2e0c) | |
2A1T
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![BU of 2a1t by Molmil](/molmil-images/mine/2a1t) | Structure of the human MCAD:ETF E165betaA complex | 分子名称: | ADENOSINE MONOPHOSPHATE, Acyl-CoA dehydrogenase, medium-chain specific, ... | 著者 | Toogood, H.S, Van Thiel, A, Scrutton, N.S, Leys, D. | 登録日 | 2005-06-21 | 公開日 | 2005-07-05 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Stabilization of Non-productive Conformations Underpins Rapid Electron Transfer to Electron-transferring Flavoprotein J.Biol.Chem., 280, 2005
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2A3D
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![BU of 2a3d by Molmil](/molmil-images/mine/2a3d) | SOLUTION STRUCTURE OF A DE NOVO DESIGNED SINGLE CHAIN THREE-HELIX BUNDLE (A3D) | 分子名称: | PROTEIN (DE NOVO THREE-HELIX BUNDLE) | 著者 | Walsh, S.T.R, Cheng, H, Bryson, J.W, Roder, H, Degrado, W.F. | 登録日 | 1999-04-01 | 公開日 | 1999-05-05 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure and dynamics of a de novo designed three-helix bundle protein. Proc.Natl.Acad.Sci.USA, 96, 1999
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2E1Q
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![BU of 2e1q by Molmil](/molmil-images/mine/2e1q) | Crystal Structure of Human Xanthine Oxidoreductase mutant, Glu803Val | 分子名称: | 2-HYDROXYBENZOIC ACID, BICARBONATE ION, CALCIUM ION, ... | 著者 | Yamaguchi, Y, Matsumura, T, Ichida, K, Okamoto, K, Nishino, T. | 登録日 | 2006-10-27 | 公開日 | 2007-09-18 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Human xanthine oxidase changes its substrate specificity to aldehyde oxidase type upon mutation of amino acid residues in the active site: roles of active site residues in binding and activation of purine substrate J.Biochem.(Tokyo), 141, 2007
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2E4T
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![BU of 2e4t by Molmil](/molmil-images/mine/2e4t) | Crystal structure of Cel44A, GH family 44 endoglucanase from Clostridium thermocellum | 分子名称: | CALCIUM ION, CHLORIDE ION, Endoglucanase, ... | 著者 | Kitago, Y, Karita, S, Watanabe, N, Sakka, K, Tanaka, I. | 登録日 | 2006-12-16 | 公開日 | 2007-09-18 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (0.96 Å) | 主引用文献 | Crystal structure of Cel44A, a glycoside hydrolase family 44 endoglucanase from Clostridium thermocellum. J.Biol.Chem., 282, 2007
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2E4M
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![BU of 2e4m by Molmil](/molmil-images/mine/2e4m) | Crystal structure of hemagglutinin subcomponent complex (HA-33/HA-17) from Clostridium botulinum serotype D strain 4947 | 分子名称: | HA-17, Main hemagglutinin component | 著者 | Hasegawa, K, Watanabe, T, Suzuki, T, Yamano, A, Niwa, K, Ohyama, T. | 登録日 | 2006-12-13 | 公開日 | 2007-06-19 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | A Novel Subunit Structure of Clostridium botulinum Serotype D Toxin Complex with Three Extended Arms J.Biol.Chem., 282, 2007
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2A72
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![BU of 2a72 by Molmil](/molmil-images/mine/2a72) | Structure of the regulator of G-protein signaling domain of RGS7 | 分子名称: | CHLORIDE ION, Regulator of G-protein signalling 7 | 著者 | Schoch, G.A, Johansson, C, Phillips, C, Debreczeni, J, Smee, C, Elkins, J.M, Sundstrom, M, Edwards, A, Arrowsmith, C, von Delft, F, Gileadi, O, Doyle, D.A, Structural Genomics Consortium (SGC) | 登録日 | 2005-07-04 | 公開日 | 2005-07-12 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits. Proc.Natl.Acad.Sci.Usa, 105, 2008
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1ZZ6
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![BU of 1zz6 by Molmil](/molmil-images/mine/1zz6) | Crystal Structure of Apo-HppE | 分子名称: | Hydroxypropylphosphonic Acid Epoxidase | 著者 | Higgins, L.J, Yan, F, Liu, P, Liu, H.W, Drennan, C.L. | 登録日 | 2005-06-13 | 公開日 | 2005-07-26 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural insight into antibiotic fosfomycin biosynthesis by a mononuclear iron enzyme Nature, 437, 2005
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1ZZQ
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![BU of 1zzq by Molmil](/molmil-images/mine/1zzq) | Rat nNOS D597N mutant with L-N(omega)-Nitroarginine-(4R)-amino-L-proline amide bound | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, D-MANNITOL, ... | 著者 | Li, H, Flinspach, M.L, Igarashi, J, Jamal, J, Yang, W, Gomez-Vidal, J.A, Litzinger, E.A, Silverman, R.B, Poulos, T.L. | 登録日 | 2005-06-14 | 公開日 | 2005-12-06 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Exploring the Binding Conformations of Bulkier Dipeptide Amide Inhibitors in Constitutive Nitric Oxide Synthases. Biochemistry, 44, 2005
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1ZZ9
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![BU of 1zz9 by Molmil](/molmil-images/mine/1zz9) | Crystal Structure of FeII HppE | 分子名称: | FE (II) ION, Hydroxypropylphosphonic Acid Epoxidase, SULFATE ION | 著者 | Higgins, L.J, Yan, F, Liu, P, Liu, H.W, Drennan, C.L. | 登録日 | 2005-06-13 | 公開日 | 2005-07-26 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural insight into antibiotic fosfomycin biosynthesis by a mononuclear iron enzyme Nature, 437, 2005
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1ZZ7
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![BU of 1zz7 by Molmil](/molmil-images/mine/1zz7) | Crystal Structure of FeII HppE in Complex with Substrate form 1 | 分子名称: | (S)-2-HYDROXYPROPYLPHOSPHONIC ACID, FE (II) ION, Hydroxyprophylphosphonic Acid Epoxidase | 著者 | Higgins, L.J, Yan, F, Liu, P, Liu, H.W, Drennan, C.L. | 登録日 | 2005-06-13 | 公開日 | 2005-07-26 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural insight into antibiotic fosfomycin biosynthesis by a mononuclear iron enzyme Nature, 437, 2005
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1X9P
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![BU of 1x9p by Molmil](/molmil-images/mine/1x9p) | The crystal structure of human adenovirus 2 penton base | 分子名称: | N-DODECYL-N,N-DIMETHYL-3-AMMONIO-1-PROPANESULFONATE, Penton protein, SULFATE ION | 著者 | Zubieta, C, Schoehn, G, Chroboczek, J, Cusack, S. | 登録日 | 2004-08-24 | 公開日 | 2005-01-18 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | The structure of the human adenovirus 2 penton Mol.Cell, 17, 2005
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2EL9
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![BU of 2el9 by Molmil](/molmil-images/mine/2el9) | Crystal structure of E.coli Histidyl-tRNA synthetase complexed with a histidyl-adenylate analogue | 分子名称: | 5'-O-[(L-HISTIDYLAMINO)SULFONYL]ADENOSINE, Histidyl-tRNA synthetase | 著者 | Yanagisawa, T, Si, S.Y, Matsuno, M, Ishii, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-03-27 | 公開日 | 2008-03-18 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structure of E.coli Histidyl-tRNA synthetase complexed with a histidyl-adenylate analogue To be published
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2DXB
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![BU of 2dxb by Molmil](/molmil-images/mine/2dxb) | Recombinant thiocyanate hydrolase comprising partially-modified cobalt centers | 分子名称: | COBALT (III) ION, PHOSPHATE ION, Thiocyanate hydrolase subunit alpha, ... | 著者 | Arakawa, T, Kawano, Y, Katayama, Y, Yohda, M, Odaka, M. | 登録日 | 2006-08-25 | 公開日 | 2007-08-28 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structural Basis for Catalytic Activation of Thiocyanate Hydrolase Involving Metal-Ligated Cysteine Modification J.Am.Chem.Soc., 131, 2009
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1XFX
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![BU of 1xfx by Molmil](/molmil-images/mine/1xfx) | Crystal structure of anthrax edema factor (EF) in complex with calmodulin in the presence of 10 millimolar exogenously added calcium chloride | 分子名称: | CALCIUM ION, Calmodulin 2, Calmodulin-sensitive adenylate cyclase, ... | 著者 | Shen, Y, Zhukovskaya, N.L, Guo, Q, Florian, J, Tang, W.J. | 登録日 | 2004-09-15 | 公開日 | 2005-05-03 | 最終更新日 | 2017-12-20 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Calcium-independent calmodulin binding and two-metal-ion catalytic mechanism of anthrax edema factor. EMBO J., 24, 2005
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2E5B
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1X8I
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![BU of 1x8i by Molmil](/molmil-images/mine/1x8i) | Crystal Structure of the Zinc Carbapenemase CphA in Complex with the Antibiotic Biapenem | 分子名称: | 5H-PYRAZOLO(1,2-A)(1,2,4)TRIAZOL-4-IUM, 6-((2-CARBOXY-6-(1-HYDROXYETHYL)-4-METHYL-7-OXO-1-AZABICYCLO(3.2.0)HEPT-2-EN-3-YL)THIO)-6,7-DIHYDRO-, HYDROXIDE, ... | 著者 | Garau, G, Dideberg, O. | 登録日 | 2004-08-18 | 公開日 | 2004-12-28 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | A Metallo-beta-lactamase Enzyme in Action: Crystal Structures of the Monozinc Carbapenemase CphA and its Complex with Biapenem J.Mol.Biol., 345, 2005
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1XCR
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![BU of 1xcr by Molmil](/molmil-images/mine/1xcr) | Crystal Structure of Longer Splice Variant of PTD012 from Homo sapiens reveals a novel Zinc-containing fold | 分子名称: | ACETIC ACID, ZINC ION, hypothetical protein PTD012 | 著者 | Manjasetty, B.A, Fieber-Erdmann, M, Roske, Y, Goetz, F, Buessow, K, Heinemann, U. | 登録日 | 2004-09-03 | 公開日 | 2005-09-27 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure of Homo sapiens PTD012 reveals a zinc-containing hydrolase fold Protein Sci., 15, 2006
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