2A8W
Crystal Structure of Human N-acetylgalactosaminyltransferase (GTA) Complexed with Beta-Methyllactoside
Summary for 2A8W
Entry DOI | 10.2210/pdb2a8w/pdb |
Related | 1ZHJ 1ZI1 1ZI3 1ZI4 1ZI5 1ZJO |
Descriptor | Histo-blood group ABO system transferase (NAGAT) [Includes: Glycoprotein-fucosylgalactoside alpha-N- acetylgalactosaminyltransferase (EC 2.4.1.40) (Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase) (Histo-blood group A transferase) (A transferase); Glycoprotein-fucosylgalactoside alpha- galactosyltransferase (EC 2.4.1.37) (Fucosylglycoprotein 3-alpha- galactosyltransferase) (Histo-blood group B transferase) (B transferase)] [Contains: Fucosylglycoprotein alpha-N- acetylgalactosaminyltransferase, soluble form], MERCURY (II) ION, CHLORIDE ION, ... (6 entities in total) |
Functional Keywords | gta, abo(h), blood groups, glycosyltransferase, retaining, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein: P16442 |
Total number of polymer chains | 1 |
Total formula weight | 35692.00 |
Authors | Letts, J.A.,Rose, N.L.,Fang, Y.R.,Barry, C.H.,Borisova, S.N.,Seto, N.O.,Palcic, M.M.,Evans, S.V. (deposition date: 2005-07-09, release date: 2005-12-13, Last modification date: 2023-08-23) |
Primary citation | Letts, J.A.,Rose, N.L.,Fang, Y.R.,Barry, C.H.,Borisova, S.N.,Seto, N.O.,Palcic, M.M.,Evans, S.V. Differential Recognition of the Type I and II H Antigen Acceptors by the Human ABO(H) Blood Group A and B Glycosyltransferases. J.Biol.Chem., 281:3625-3632, 2006 Cited by PubMed: 16326711DOI: 10.1074/jbc.M507620200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.59 Å) |
Structure validation
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