2A8W
Crystal Structure of Human N-acetylgalactosaminyltransferase (GTA) Complexed with Beta-Methyllactoside
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Histo-blood group ABO system transferase (NAGAT) [Includes: Glycoprotein-fucosylgalactoside alpha-N- acetylgalactosaminyltransferase (EC 2.4.1.40) (Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase) (Histo-blood group A transferase) (A transferase); Glycoprotein-fucosylgalactoside alpha- galactosyltransferase (EC 2.4.1.37) (Fucosylglycoprotein 3-alpha- galactosyltransferase) (Histo-blood group B transferase) (B transferase)] [Contains: Fucosylglycoprotein alpha-N- acetylgalactosaminyltransferase, soluble form] | polymer | 293 | 34194.5 | 1 | UniProt (P16442) Pfam (PF03414) In PDB | Homo sapiens (human) | |
| 2 | A | MERCURY (II) ION | non-polymer | 200.6 | 5 | Chemie (HG) | |||
| 3 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | A | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) | |||
| 5 | A | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 1 | Chemie (UDP) | |||
| 6 | water | water | 18.0 | 226 | Chemie (HOH) |
Sequence modifications
A: 64 - 354 (UniProt: P16442)
| PDB | External Database | Details |
|---|---|---|
| Phe 62 | - | cloning artifact |
| Met 63 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34194.5 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1497.5 | |
| All* | Total formula weight | 35692.0 |
