4BJ9

Crystal structure of human tankyrase 2 in complex with EB-47

Summary for 4BJ9

Entry DOI	10.2210/pdb4bj9/pdb
Related	4BJB 4BJC
Descriptor	TANKYRASE-2, ZINC ION, SULFATE ION, ... (6 entities in total)
Functional Keywords	transferase, diphtheria toxin like fold, adp-ribosylation, inhibitor
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Cytoplasm: Q9H2K2
Total number of polymer chains	2
Total formula weight	56373.84
Authors	Haikarainen, T.,Narwal, M.,Lehtio, L. (deposition date: 2013-04-17, release date: 2013-12-11, Last modification date: 2014-06-18)
Primary citation	Haikarainen, T.,Narwal, M.,Joensuu, P.,Lehtio, L. Evaluation and Structural Basis for the Inhibition of Tankyrases by Parp Inhibitors Acs Med.Chem.Lett., 5:18-, 2014 Cited by PubMed: 24900770 DOI: 10.1021/ML400292S PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation