8VWS
 
 | | Nucleosome containing 8oxoG at SHL-6 | | 分子名称: | 601 I strand (non-damaged strand), 601 J strand (damaged strand), Histone H2A type 1, ... | | 著者 | Weaver, T.M, Ling, J.A, Freudenthal, B.D. | | 登録日 | 2024-02-02 | | 公開日 | 2024-10-30 | | 最終更新日 | 2025-05-28 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Contributing factors to the oxidation-induced mutational landscape in human cells.
Nat Commun, 15, 2024
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5CP6
 | | Nucleosome Core Particle with Adducts from the Anticancer Compound, [(eta6-5,8,9,10-tetrahydroanthracene)Ru(ethylenediamine)Cl][PF6] | | 分子名称: | (ethane6-5,8,9,10-tetrahydroanthracene)Ru(II)(ethylene-diamine)Cl, DNA (145-MER), Histone H2A, ... | | 著者 | Ma, Z, Adhireksan, Z, Murray, B.S, Dyson, P.J, Davey, C.A. | | 登録日 | 2015-07-21 | | 公開日 | 2016-06-01 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | An Organometallic Compound which Exhibits a DNA Topology-Dependent One-Stranded Intercalation Mode.
Angew.Chem.Int.Ed.Engl., 55, 2016
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6FQ8
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6FQ6
 | | Class 2 : distorted nucleosome | | 分子名称: | DNA (147-MER), Histone H2A, Histone H2B, ... | | 著者 | Bilokapic, S, Halic, M. | | 登録日 | 2018-02-13 | | 公開日 | 2018-04-18 | | 最終更新日 | 2025-07-02 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structural rearrangements of the histone octamer translocate DNA.
Nat Commun, 9, 2018
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6FQ5
 | | Class 1 : canonical nucleosome | | 分子名称: | DNA (147-MER), Histone H2A, Histone H2B, ... | | 著者 | Bilokapic, S, Halic, M. | | 登録日 | 2018-02-13 | | 公開日 | 2018-04-18 | | 最終更新日 | 2025-07-02 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structural rearrangements of the histone octamer translocate DNA.
Nat Commun, 9, 2018
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7UX9
 | | Arabidopsis DDM1 bound to nucleosome (H2A.W, H2B, H3.3, H4, with 147 bp DNA) | | 分子名称: | ATP-dependent DNA helicase DDM1, DNA (antisense strand), DNA (sense strand), ... | | 著者 | Ipsaro, J.J, Adams, D.W, Joshua-Tor, L. | | 登録日 | 2022-05-05 | | 公開日 | 2023-08-09 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Chromatin remodeling of histone H3 variants by DDM1 underlies epigenetic inheritance of DNA methylation.
Cell, 186, 2023
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6SLE
 | | Structure of Reductive Aminase from Neosartorya fumigata in complex with NADP+ | | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Oxidoreductase, putative | | 著者 | Sharma, M, Mangas-Sanchez, J, Turner, N.J, Grogan, G. | | 登録日 | 2019-08-19 | | 公開日 | 2020-06-24 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.77 Å) | | 主引用文献 | Asymmetric synthesis of primary amines catalyzed by thermotolerant fungal reductive aminases.
Chem Sci, 11, 2020
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6SKX
 | | Structure of Reductive Aminase from Neosartorya fumigata | | 分子名称: | Oxidoreductase, putative | | 著者 | Sharma, M, Mangas-Sanchez, J, Turner, N.J, Grogan, G. | | 登録日 | 2019-08-16 | | 公開日 | 2020-06-24 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Asymmetric synthesis of primary amines catalyzed by thermotolerant fungal reductive aminases.
Chem Sci, 11, 2020
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4FYI
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5DNM
 | | Nucleosome core particle containing adducts of ruthenium(II)-toluene PTA complex | | 分子名称: | DNA (145-MER), Histone H2A, Histone H2B 1.1, ... | | 著者 | Adhireksan, Z, Muhammad, R, Davey, C.A. | | 登録日 | 2015-09-10 | | 公開日 | 2016-09-14 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | Allosteric cross-talk in chromatin can mediate drug-drug synergy
Nat Commun, 8, 2017
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5DNN
 | | Nucleosome core particle containing adducts of gold(I)-triethylphosphane and ruthenium(II)-toluene PTA complexes | | 分子名称: | DNA (145-MER), Histone H2A, Histone H2B 1.1, ... | | 著者 | Adhireksan, Z, Ma, Z, Davey, C.A. | | 登録日 | 2015-09-10 | | 公開日 | 2016-09-14 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Allosteric cross-talk in chromatin can mediate drug-drug synergy
Nat Commun, 8, 2017
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8G8B
 | | Nucleosome with human nMatn1 sequence in complex with Human Oct4 | | 分子名称: | Histone H2A, Histone H2B, Histone H3, ... | | 著者 | Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M. | | 登録日 | 2023-02-17 | | 公開日 | 2023-03-22 | | 最終更新日 | 2025-05-14 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Histone modifications regulate pioneer transcription factor cooperativity.
Nature, 619, 2023
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4DO9
 | | Ternary complex of dna polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-monofluoromethylene triphosphate: stereoselective binding of r-isomer | | 分子名称: | 2'-DEOXY-5'-O-[(R)-{[(R)-[(R)-FLUORO(PHOSPHONO)METHYL](HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]GUANOSINE, C C G A C C G C G C A T C A G C, CHLORIDE ION, ... | | 著者 | Batra, V.K. | | 登録日 | 2012-02-09 | | 公開日 | 2012-06-13 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Beta,gamma-CHF- and beta,gamma-CHCl-dGTP Diastereomers: Synthesis, Discrete (31)P NMR Signatures, and Absolute Configurations of New Stereochemical Probes for DNA Polymerases
J.Am.Chem.Soc., 134, 2012
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4DOB
 | | Ternary complex of DNA polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-monochlororomethylene triphosphate: Stereoselective binding of R-isomer | | 分子名称: | 5'-O-[(R)-{[(R)-[(R)-chloro(phosphono)methyl](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]-2'-deoxyguanosine, C C G A C C G C G C A T C A G C, CHLORIDE ION, ... | | 著者 | Batra, V.K. | | 登録日 | 2012-02-09 | | 公開日 | 2012-06-13 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Beta,Gamma-CHF- and beta,gamma-CHCl-dGTP Diastereomers: Synthesis, Discrete (31)P NMR Signatures, and Absolute Configurations of New Stereochemical Probes for DNA Polymerases
J.Am.Chem.Soc., 134, 2012
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3AAR
 | | Crystal structure of Lp1NTPDase from Legionella pneumophila in complex with AMPPNP | | 分子名称: | Ectonucleoside triphosphate diphosphohydrolase I, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | 著者 | Ge, H, Vivian, J.P, Beddoe, T, Rossjohn, J. | | 登録日 | 2009-11-24 | | 公開日 | 2010-02-09 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Crystal Structure of a Legionella pneumophila Ecto -Triphosphate Diphosphohydrolase, A Structural and Functional Homolog of the Eukaryotic NTPDases
Structure, 18, 2010
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3AAP
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5FHI
 | | Crystallographic structure of PsoE without Co | | 分子名称: | GLUTATHIONE, Glutathione S-transferase, putative | | 著者 | Hara, K, Hashimoto, H, Yamamoto, T, Tsunematsu, Y, Watanabe, K. | | 登録日 | 2015-12-22 | | 公開日 | 2016-04-20 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | | 主引用文献 | Oxidative trans to cis Isomerization of Olefins in Polyketide Biosynthesis.
Angew. Chem. Int. Ed. Engl., 55, 2016
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5F8B
 | | Crystallographic Structure of PsoE with Co | | 分子名称: | (5~{S},8~{S},9~{R})-2-[(~{E})-hex-1-enyl]-8-methoxy-3-methyl-9-oxidanyl-8-(phenylcarbonyl)-1-oxa-7-azaspiro[4.4]non-2-ene-4,6-dione, COBALT (II) ION, GLUTATHIONE, ... | | 著者 | Hara, K, Hashimoto, H, Yamamoto, T, Tsunematsu, Y, Watanabe, K. | | 登録日 | 2015-12-09 | | 公開日 | 2016-04-20 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | | 主引用文献 | Oxidative trans to cis Isomerization of Olefins in Polyketide Biosynthesis.
Angew. Chem. Int. Ed. Engl., 55, 2016
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4O44
 | | Crystal Structure of HIV-1 Reverse Transcriptase in complex with 4-((4-(mesitylamino)-6-(3-morpholinopropoxy)-1,3,5-triazin-2-yl)amino)benzonitrile (JLJ529), a non-nucleoside inhibitor | | 分子名称: | 4-({4-[3-(morpholin-4-yl)propoxy]-6-[(2,4,6-trimethylphenyl)amino]-1,3,5-triazin-2-yl}amino)benzonitrile, HIV-1 reverse transcriptase, p51 subunit, ... | | 著者 | Mislak, A.C, Frey, K.M, Anderson, K.S. | | 登録日 | 2013-12-18 | | 公開日 | 2014-05-21 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.889 Å) | | 主引用文献 | A mechanistic and structural investigation of modified derivatives of the diaryltriazine class of NNRTIs targeting HIV-1 reverse transcriptase.
Biochim.Biophys.Acta, 1840, 2014
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4O4G
 | | Crystal Structure of HIV-1 Reverse Transcriptase in complex with 4-((4-(mesitylamino)-1,3,5-triazin-2-yl)amino)benzonitrile (JLJ527), a non-nucleoside inhibitor | | 分子名称: | 4-({4-[(2,4,6-trimethylphenyl)amino]-1,3,5-triazin-2-yl}amino)benzonitrile, HIV-1 reverse transcriptase, p51 subunit, ... | | 著者 | Mislak, A.C, Frey, K.M. | | 登録日 | 2013-12-18 | | 公開日 | 2014-11-05 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.712 Å) | | 主引用文献 | A mechanistic and structural investigation of modified derivatives of the diaryltriazine class of NNRTIs targeting HIV-1 reverse transcriptase.
Biochim.Biophys.Acta, 1840, 2014
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7KTQ
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1L1L
 | | CRYSTAL STRUCTURE OF B-12 DEPENDENT (CLASS II) RIBONUCLEOTIDE REDUCTASE | | 分子名称: | RIBONUCLEOSIDE TRIPHOSPHATE REDUCTASE | | 著者 | Sintchak, M.D, Arjara, G, Kellogg, B.A, Stubbe, J, Drennan, C.L. | | 登録日 | 2002-02-18 | | 公開日 | 2002-04-10 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | The crystal structure of class II ribonucleotide reductase reveals how an allosterically regulated monomer mimics a dimer.
Nat.Struct.Biol., 9, 2002
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4ENO
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1ZZD
 | | Structures of Yeast Ribonucleotide Reductase I | | 分子名称: | Ribonucleoside-diphosphate reductase large chain 1, Ribonucleoside-diphosphate reductase small chain 2 | | 著者 | Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C. | | 登録日 | 2005-06-13 | | 公開日 | 2006-03-07 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation
Proc.Natl.Acad.Sci.Usa, 103, 2006
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7YJ0
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