PDB: 37819 件ウェブページステータス検索Chemie searchBIRD

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1KRM	Crystal structure of bovine adenosine deaminase complexed with 6-hydroxyl-1,6-dihydropurine riboside 分子名称: 6-HYDROXY-1,6-DIHYDRO PURINE NUCLEOSIDE, ZINC ION, adenosine deaminase 著者 Kinoshita, T. 登録日 2002-01-10 公開日 2003-01-14 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of bovine adenosine deaminase complexed with 6-hydroxy-1,6-dihydropurine riboside. Acta Crystallogr.,Sect.D, 59, 2003
5GPK	Crystal structure of Ccp1 mutant 分子名称: Putative nucleosome assembly protein C36B7.08c 著者 Yin, F, Gao, F, Chen, Y. 登録日 2016-08-03 公開日 2016-11-30 実験手法 X-RAY DIFFRACTION (2.103 Å) 主引用文献 Ccp1 Homodimer Mediates Chromatin Integrity by Antagonizing CENP-A Loading Mol.Cell, 64, 2016
6KXV	Crystal structure of a nucleosome containing Leishmania histone H3 分子名称: DNA (146-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... 著者 Dacher, M, Taguchi, H, Kujirai, T, Kurumizaka, H. 登録日 2019-09-13 公開日 2020-07-22 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.63 Å) 主引用文献 Incorporation and influence of Leishmania histone H3 in chromatin. Nucleic Acids Res., 47, 2019
5GPL	Crystal structure of Ccp1 分子名称: Putative nucleosome assembly protein C36B7.08c 著者 Yin, F, Gao, F, Chen, Y. 登録日 2016-08-03 公開日 2016-11-30 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Ccp1 Homodimer Mediates Chromatin Integrity by Antagonizing CENP-A Loading Mol.Cell, 64, 2016
8OSL	Cryo-EM structure of CLOCK-BMAL1 bound to the native Por enhancer nucleosome (map 2, additional 3D classification and flexible refinement) 分子名称: Basic helix-loop-helix ARNT-like protein 1, Circadian locomoter output cycles protein kaput, DNA (147-MER), ... 著者 Michael, A.K, Stoos, L, Kempf, G, Cavadini, S, Thoma, N. 登録日 2023-04-19 公開日 2023-05-24 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (4.9 Å) 主引用文献 Cooperation between bHLH transcription factors and histones for DNA access. Nature, 619, 2023
1R6A	Structure of the dengue virus 2'O methyltransferase in complex with s-adenosyl homocysteine and ribavirin 5' triphosphate 分子名称: Genome polyprotein, RIBAVIRIN MONOPHOSPHATE, S-ADENOSYL-L-HOMOCYSTEINE, ... 著者 Benarroch, D, Egloff, M.P, Mulard, L, Romette, J.L, Canard, B. 登録日 2003-10-15 公開日 2004-09-21 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 A structural basis for the inhibition of the NS5 dengue virus mRNA 2'-O-methyltransferase domain by ribavirin 5'-triphosphate. J.Biol.Chem., 279, 2004
8WH5	Structure of DDM1-nucleosome complex in the apo state 分子名称: ATP-dependent DNA helicase DDM1, DNA (antisense strand), DNA (sense strand), ... 著者 Liu, Y, Zhang, Z, Du, J. 登録日 2023-09-22 公開日 2024-04-17 実験手法 ELECTRON MICROSCOPY (3.58 Å) 主引用文献 Molecular basis of chromatin remodelling by DDM1 involved in plant DNA methylation. Nat.Plants, 10, 2024
8WHA	Structure of DDM1-nucleosome complex in the ADP-BeFx state with DDM1 bound to SHL2 and SHL-2 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase DDM1, BERYLLIUM TRIFLUORIDE ION, ... 著者 Liu, Y, Zhang, Z, Du, J. 登録日 2023-09-22 公開日 2024-04-17 実験手法 ELECTRON MICROSCOPY (4.05 Å) 主引用文献 Molecular basis of chromatin remodelling by DDM1 involved in plant DNA methylation. Nat.Plants, 10, 2024
8WH9	Structure of DDM1-nucleosome complex in ADP-BeFx state 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase DDM1, BERYLLIUM TRIFLUORIDE ION, ... 著者 Liu, Y, Zhang, Z, Du, J. 登録日 2023-09-22 公開日 2024-04-17 実験手法 ELECTRON MICROSCOPY (3.31 Å) 主引用文献 Molecular basis of chromatin remodelling by DDM1 involved in plant DNA methylation. Nat.Plants, 10, 2024
4DC3	Adenosine kinase from Schistosoma mansoni in complex with 2-fluoroadenosine 分子名称: 2-(6-AMINO-2-FLUORO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL, ADENOSINE, Adenosine kinase, ... 著者 Romanello, L, Bachega, F.R, Garatt, R.C, DeMarco, R, Brandao-neto, J, Pereira, H.M. 登録日 2012-01-17 公開日 2012-11-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Adenosine kinase from Schistosoma mansoni: structural basis for the differential incorporation of nucleoside analogues. Acta Crystallogr.,Sect.D, 69, 2013
1ZOS	Structure of 5'-methylthionadenosine/S-Adenosylhomocysteine nucleosidase from S. pneumoniae with a transition-state inhibitor MT-ImmA 分子名称: (3S,4R)-2-(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-5-[(METHYLSULFANYL)METHYL]PYRROLIDINE-3,4-DIOL, 5'-methylthioadenosine / S-adenosylhomocysteine nucleosidase 著者 Shi, W, Singh, V, Zhen, R, Tyler, P.C, Furneaux, R.H, Almo, S.C, Schramm, V.L. 登録日 2005-05-13 公開日 2006-04-25 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure and inhibition of a quorum sensing target from Streptococcus pneumoniae. Biochemistry, 45, 2006
4MK7	Hepatitis C Virus polymerase NS5B genotype 1b (BK) in complex with inhibitor 2 (3-(3-tert-butyl-4-methoxyphenyl)pyridin-2(1H)-one) 分子名称: 3-(3-tert-butyl-4-methoxyphenyl)pyridin-2(1H)-one, DIMETHYL SULFOXIDE, MAGNESIUM ION, ... 著者 Harris, S.F, Wong, A. 登録日 2013-09-04 公開日 2013-10-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Discovery of a Novel Series of Potent Non-Nucleoside Inhibitors of Hepatitis C Virus NS5B. J.Med.Chem., 56, 2013
4MK8	Hepatitis C Virus polymerase NS5B genotype 1b (BK) in complex with inhibitor 4 (N-(4-{2-[3-tert-butyl-2-methoxy-5-(2-oxo-1,2-dihydropyridin-3-yl)phenyl]ethyl}phenyl)methanesulfonamide) 分子名称: DIMETHYL SULFOXIDE, GLYCEROL, N-(4-{2-[3-tert-butyl-2-methoxy-5-(2-oxo-1,2-dihydropyridin-3-yl)phenyl]ethyl}phenyl)methanesulfonamide, ... 著者 Harris, S.F, Wong, A. 登録日 2013-09-04 公開日 2013-10-09 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Discovery of a Novel Series of Potent Non-Nucleoside Inhibitors of Hepatitis C Virus NS5B. J.Med.Chem., 56, 2013
1TSN	THYMIDYLATE SYNTHASE TERNARY COMPLEX WITH FDUMP AND METHYLENETETRAHYDROFOLATE 分子名称: 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID, PHOSPHATE ION, ... 著者 Hyatt, D.C, Maley, F, Montfort, W.R. 登録日 1996-12-02 公開日 1997-07-07 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Use of strain in a stereospecific catalytic mechanism: crystal structures of Escherichia coli thymidylate synthase bound to FdUMP and methylenetetrahydrofolate. Biochemistry, 36, 1997
1TZ3	crystal structure of aminoimidazole riboside kinase complexed with aminoimidazole riboside 分子名称: 5-AMINOIMIDAZOLE RIBONUCLEOSIDE, POTASSIUM ION, putative sugar kinase 著者 Zhang, Y, Dougherty, M, Downs, D.M, Ealick, S.E. 登録日 2004-07-09 公開日 2004-10-12 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal Structure of an Aminoimidazole Riboside Kinase from Salmonella enterica; Implications for the Evolution of the Ribokinase Superfamily STRUCTURE, 12, 2004
1TZ6	Crystal structure of aminoimidazole riboside kinase from Salmonella enterica complexed with aminoimidazole riboside and ATP analog 分子名称: 5-AMINOIMIDAZOLE RIBONUCLEOSIDE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... 著者 Zhang, Y, Dougherty, M, Downs, D.M, Ealick, S.E. 登録日 2004-07-09 公開日 2004-10-12 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal Structure of an Aminoimidazole Riboside Kinase from Salmonella enterica; Implications for the Evolution of the Ribokinase Superfamily STRUCTURE, 12, 2004
4OQN	Crystal structure of thymidine kinase from herpes simplex virus type 1 in complex with EdU 分子名称: 2'-deoxy-5-ethynyluridine, SULFATE ION, Thymidine kinase 著者 Pernot, L, Neef, A.B, Westermaier, Y, Perozzo, R, Luedtke, N.W, Scapozza, L. 登録日 2014-02-10 公開日 2014-08-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of thymidine kinase from herpes simplex virus type 1 in complex with EdU To be Published
4OQX	Crystal structure of thymidine kinase from herpes simplex virus type 1 in complex with Me-ARA-EdU 分子名称: 1-(2-deoxy-2-methyl-beta-D-arabinofuranosyl)-5-ethynylpyrimidine-2,4(1H,3H)-dione, SULFATE ION, Thymidine kinase 著者 Pernot, L, Neef, A.B, Westermaier, Y, Perozzo, R, Luedtke, N, Scapozza, L. 登録日 2014-02-10 公開日 2014-08-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of HSV1-TK complexed with Me-ARA-EdU To be Published
8OTT	MYC-MAX bound to a nucleosome at SHL+5.8 分子名称: DNA (144-MER), Histone H2A type 1-B/E, Histone H2A type 1-K, ... 著者 Stoos, L, Michael, A.K, Kempf, G, Kater, L, Cavadini, S, Thoma, N. 登録日 2023-04-21 公開日 2023-05-24 最終更新日 2024-11-06 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Cooperation between bHLH transcription factors and histones for DNA access. Nature, 619, 2023
3SEA	Structure of Rheb-Y35A mutant in GDP- and GMPPNP-bound forms 分子名称: ACETATE ION, GTP-binding protein Rheb, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Mazhab-Jafari, M.T, Marshall, C.B, Ishiyama, N, Vuk, S, Ikura, M. 登録日 2011-06-10 公開日 2012-06-20 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 An Autoinhibited Noncanonical Mechanism of GTP Hydrolysis by Rheb Maintains mTORC1 Homeostasis. Structure, 20, 2012
4IQT	Tdt core in complex with inhibitor 6-[4-(3-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid 分子名称: 6-[4-(3-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid, DNA nucleotidylexotransferase 著者 Gouge, J, Delarue, M. 登録日 2013-01-13 公開日 2013-09-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 New nucleotide-competitive non-nucleoside inhibitors of terminal deoxynucleotidyl transferase: discovery, characterization, and crystal structure in complex with the target. J.Med.Chem., 56, 2013
8PP7	human RYBP-PRC1 bound to mononucleosome 分子名称: DNA (215-mer), E3 ubiquitin-protein ligase RING2, Histone H2A, ... 著者 Ciapponi, M, Benda, C, Mueller, J. 登録日 2023-07-06 公開日 2024-03-27 最終更新日 2024-07-31 実験手法 ELECTRON MICROSCOPY (2.91 Å) 主引用文献 Structural basis of the histone ubiquitination read-write mechanism of RYBP-PRC1. Nat.Struct.Mol.Biol., 31, 2024
8PP6	human RYBP-PRC1 bound to H2AK118ub1 nucleosome 分子名称: DNA (215-MER), Histone H2A, Histone H2B, ... 著者 Ciapponi, M, Benda, C, Mueller, J. 登録日 2023-07-06 公開日 2024-04-03 最終更新日 2024-07-31 実験手法 ELECTRON MICROSCOPY (3.18 Å) 主引用文献 Structural basis of the histone ubiquitination read-write mechanism of RYBP-PRC1. Nat.Struct.Mol.Biol., 31, 2024
4IQU	Tdt core in complex with inhibitor (2Z,5E)-6-[4-(4-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid 分子名称: (2Z,5E)-6-[4-(4-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid, DNA nucleotidylexotransferase, SODIUM ION 著者 Gouge, J, Delarue, M. 登録日 2013-01-13 公開日 2013-09-04 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 New nucleotide-competitive non-nucleoside inhibitors of terminal deoxynucleotidyl transferase: discovery, characterization, and crystal structure in complex with the target. J.Med.Chem., 56, 2013
4IQV	Tdt core in complex with inhibitor 6-[4-(3-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid and ssDNA 分子名称: 5'-D(*GP*CP*CP*G)-3', 6-[4-(3-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid, DNA nucleotidylexotransferase, ... 著者 Gouge, J, Delarue, M. 登録日 2013-01-13 公開日 2013-09-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 New nucleotide-competitive non-nucleoside inhibitors of terminal deoxynucleotidyl transferase: discovery, characterization, and crystal structure in complex with the target. J.Med.Chem., 56, 2013

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