PDB: 35756 件ウェブページステータス検索Chemie searchBIRD

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4M54	The structure of the staphyloferrin B precursor biosynthetic enzyme SbnB bound to N-(1-amino-1-carboxyl-2-ethyl)-glutamic acid and NADH 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, CHLORIDE ION, N-[(2S)-2-amino-2-carboxyethyl]-L-glutamic acid, ... 著者 Kobylarz, M.J, Murphy, M.E.P. 登録日 2013-08-07 公開日 2014-07-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 Synthesis of L-2,3-diaminopropionic acid, a siderophore and antibiotic precursor. Chem.Biol., 21, 2014
5Y8M	Mycobacterium tuberculosis 3-Hydroxyisobutyrate dehydrogenase (MtHIBADH) + NAD + (R)-3-hydroxyisobutyrate (R-HIBA) 分子名称: (2R)-3-HYDROXY-2-METHYLPROPANOIC ACID, (2~{S})-2-methylpentanedioic acid, ACRYLIC ACID, ... 著者 Srikalaivani, R, Singh, A, Surolia, A, Vijayan, M. 登録日 2017-08-21 公開日 2018-07-11 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Structure, interactions and action ofMycobacterium tuberculosis3-hydroxyisobutyric acid dehydrogenase. Biochem. J., 475, 2018
3EFV	Crystal Structure of a Putative Succinate-Semialdehyde Dehydrogenase from Salmonella typhimurium LT2 with bound NAD 分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Putative succinate-semialdehyde dehydrogenase 著者 Brunzelle, J.S, Evdokimova, E, Kudritska, M, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2008-09-10 公開日 2008-11-04 最終更新日 2013-06-12 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure and activity of the NAD(P)(+) -dependent succinate semialdehyde dehydrogenase YneI from Salmonella typhimurium. Proteins, 81, 2013
2J6I	Candida boidinii formate dehydrogenase (FDH) C-terminal mutant 分子名称: FORMATE DEHYDROGENASE, TETRAETHYLENE GLYCOL 著者 Schirwitz, K, Schmidt, A, Lamzin, V.S. 登録日 2006-09-29 公開日 2007-06-05 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 High-Resolution Structures of Formate Dehydrogenase from Candida Boidinii. Protein Sci., 16, 2007
6AA5	Crystal structure of MTH1 in complex with 3-isomangostin 分子名称: 5,9-dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methylbut-2-en-1-yl)-3,4-dihydro-2H,6H-pyrano[3,2-b]xanthen-6-one, 7,8-dihydro-8-oxoguanine triphosphatase, SULFATE ION, ... 著者 Yokoyama, T, Kitakami, R, Mizuguchi, M. 登録日 2018-07-17 公開日 2019-03-06 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.901 Å) 主引用文献 Discovery of a new class of MTH1 inhibitor by X-ray crystallographic screening. Eur J Med Chem, 167, 2019
4PZC	Crystal structure of (S)-3-hydroxybutyryl-CoA dehydrogenase PaaH1 from Ralstonia eutropha 分子名称: 3-Hydroxyacyl-CoA dehydrogenase 著者 Kim, J, Chang, J.H, Kim, K.J. 登録日 2014-03-29 公開日 2015-02-11 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure and biochemical properties of the (S)-3-hydroxybutyryl-CoA dehydrogenase PaaH1 from Ralstonia eutropha Biochem.Biophys.Res.Commun., 448, 2014
4LYM	CRYSTAL STRUCTURE OF LOW HUMIDITY TETRAGONAL LYSOZYME AT 2.1-ANGSTROMS RESOLUTION. VARIABILITY IN HYDRATION SHELL AND ITS STRUCTURAL CONSEQUENCES 分子名称: HEN EGG WHITE LYSOZYME 著者 Kodandapani, R, Suresh, C.G, Vijayan, M. 登録日 1990-07-30 公開日 1991-10-15 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of low humidity tetragonal lysozyme at 2.1-A resolution. Variability in hydration shell and its structural consequences. J.Biol.Chem., 265, 1990
6ACF	structure of leucine dehydrogenase from Geobacillus stearothermophilus by cryo-EM 分子名称: Leucine dehydrogenase 著者 Yamaguchi, H, Kamegawa, A, Nakata, K, Kashiwagi, T, Mizukoshi, T, Fujiyoshi, Y, Tani, K. 登録日 2018-07-26 公開日 2018-12-26 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structural insights into thermostabilization of leucine dehydrogenase from its atomic structure by cryo-electron microscopy J. Struct. Biol., 205, 2019
2J75	Beta-glucosidase from Thermotoga maritima in complex with noeuromycin 分子名称: (2R,3S,4R,5R)-5-(HYDROXYMETHYL)PIPERIDINE-2,3,4-TRIOL, ACETATE ION, BETA-GLUCOSIDASE A, ... 著者 Gloster, T.M, Meloncelli, P, Stick, R.V, Zechel, D, Davies, G.J. 登録日 2006-10-06 公開日 2006-12-11 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Glycosidase Inhibition: An Assessment of the Binding of 18 Putative Transition-State Mimics. J.Am.Chem.Soc., 129, 2007
4LYT	COMPARISON OF RADIATION-INDUCED DECAY AND STRUCTURE REFINEMENT FROM X-RAY DATA COLLECTED FROM LYSOZYME CRYSTALS AT LOW AND AMBIENT TEMPERATURES 分子名称: HEN EGG WHITE LYSOZYME 著者 Dewan, J.C, Young, A.C.M, Tilton, R.F. 登録日 1992-03-20 公開日 1993-10-31 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Comparison of Radiation-Induced Decay and Structure Refinement from X-Ray Data Collected from Lysozyme Crystals at Low and Ambient Temperatures J.Appl.Crystallogr., 26, 1993
2J8G	Crystal structure of the modular Cpl-1 endolysin complexed with a peptidoglycan analogue (E94Q mutant in complex with a tetrasaccharide- pentapeptide) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-N-acetyl-beta-muramic acid-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ALANINE, D-GLUTAMIC ACID, ... 著者 Perez-Dorado, I, Hermoso, J.A. 登録日 2006-10-25 公開日 2007-07-03 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Elucidation of the Molecular Recognition of Bacterial Cell Wall by Modular Pneumococcal Phage Endolysin Cpl-1. J.Biol.Chem., 282, 2007
6GPA	Beta-1,4-galactanase from Bacteroides thetaiotaomicron with galactose 分子名称: Arabinogalactan endo-beta-1,4-galactanase, beta-D-galactopyranose 著者 Hekelaar, J, Boger, M, Leeuwen van, S.S, Lammerts van Bueren, A, Dijkhuizen, L. 登録日 2018-06-05 公開日 2018-12-26 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Structural and functional characterization of a family GH53 beta-1,4-galactanase from Bacteroides thetaiotaomicron that facilitates degradation of prebiotic galactooligosaccharides. J. Struct. Biol., 205, 2019
4PZE	Crystal structure of (S)-3-hydroxybutyryl-CoA dehydrogenase PaaH1 in complex with acetoacetyl-CoA 分子名称: 3-Hydroxyacyl-CoA dehydrogenase, ACETOACETYL-COENZYME A 著者 Kim, J, Chang, J.H, Kim, K.J. 登録日 2014-03-29 公開日 2015-04-22 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure and biochemical properties of the (S)-3-hydroxybutyryl-CoA dehydrogenase PaaH1 from Ralstonia eutropha Biochem.Biophys.Res.Commun., 448, 2014
3IJ7	Directed 'in situ' Elongation as a Strategy to Characterize the Covalent Glycosyl-Enzyme Catalytic Intermediate of Human Pancreatic a-Amylase 分子名称: 4-O-methyl-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranosyl fluoride, 4-O-methyl-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-2)-5-fluoro-alpha-L-idopyranose, CALCIUM ION, ... 著者 Li, C, Zhang, R, Withers, S.G, Brayer, G.D. 登録日 2009-08-03 公開日 2009-10-27 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Directed "in situ" inhibitor elongation as a strategy to structurally characterize the covalent glycosyl-enzyme intermediate of human pancreatic alpha-amylase Biochemistry, 48, 2009
3IJP	Crystal structure of dihydrodipicolinate reductase from bartonella henselae at 2.0A resolution 分子名称: CHLORIDE ION, Dihydrodipicolinate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2009-08-04 公開日 2009-08-11 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The crystal structure of dihydrodipicolinate reductase from the human-pathogenic bacterium Bartonella henselae strain Houston-1 at 2.3 angstrom resolution. Acta Crystallogr F Struct Biol Commun, 72, 2016
3F98	Crystal structure of human plasma platelet activating factor acetylhydrolase covalently inhibited by tabun 分子名称: FORMIC ACID, Platelet-activating factor acetylhydrolase, R-ETHYL N,N-DIMETHYLPHOSPHONAMIDATE 著者 Samanta, U, Bahnson, B.J. 登録日 2008-11-13 公開日 2009-06-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structures of human group-VIIA phospholipase A2 inhibited by organophosphorus nerve agents exhibit non-aged complexes. Biochem Pharmacol, 78, 2009
5Y5H	SF-ROX structure of cytochrome P450nor (NO-bound state) determined at SACLA 分子名称: GLYCEROL, NADP nitrous oxide-forming nitric oxide reductase, NITRIC OXIDE, ... 著者 Tosha, T, Nomura, T, Nishida, T, Yamagiwa, R, Yamashita, K, Hirata, K, Ueno, G, Kimura, T, Hisano, T, Muramoto, K, Sawai, H, Takeda, H, Yamashita, A, Murakami, H, Owada, S, Tono, K, Yabashi, M, Yamamoto, M, Ago, H, Sugimoto, H, Shiro, Y, Kubo, M. 登録日 2017-08-09 公開日 2017-12-06 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Capturing an initial intermediate during the P450nor enzymatic reaction using time-resolved XFEL crystallography and caged-substrate. Nat Commun, 8, 2017
6EN4	SF3b core in complex with a splicing modulator 分子名称: PHD finger-like domain-containing protein 5A, Splicing factor 3B subunit 1, Splicing factor 3B subunit 3, ... 著者 Cretu, C, Pena, V. 登録日 2017-10-04 公開日 2018-06-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.08 Å) 主引用文献 Structural Basis of Splicing Modulation by Antitumor Macrolide Compounds. Mol. Cell, 70, 2018
7PJN	Crystal Structure of Ivosidenib-resistant IDH1 variant R132C S280F in complex with NADPH and inhibitor DS-1001B 分子名称: (E)-3-(1-(5-(2-fluoropropan-2-yl)-3-(2,4,6-trichlorophenyl)isoxazole-4-carbonyl)-3-methyl-1H-indol-4-yl)acrylic acid, CITRIC ACID, GLYCEROL, ... 著者 Reinbold, R, Rabe, P, Abboud, M.I, Schofield, C.J, Clifton, I.J. 登録日 2021-08-24 公開日 2022-07-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Resistance to the isocitrate dehydrogenase 1 mutant inhibitor ivosidenib can be overcome by alternative dimer-interface binding inhibitors. Nat Commun, 13, 2022
6AFH	DJ-1 with compound 10 分子名称: 1-(2-phenylethyl)indole-2,3-dione, CHLORIDE ION, Protein/nucleic acid deglycase DJ-1 著者 Caaveiro, J.M.M, Tashiro, S, Tsumoto, K. 登録日 2018-08-08 公開日 2018-08-29 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1. ACS Chem. Biol., 13, 2018
2J7H	Beta-glucosidase from Thermotoga maritima in complex with azafagomine 分子名称: ACETATE ION, AZAFAGOMINE, BETA-GLUCOSIDASE A, ... 著者 Gloster, T.M, Meloncelli, P, Stick, R.V, Zechel, D, Davies, G.J. 登録日 2006-10-08 公開日 2006-10-18 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Glycosidase Inhibition: An Assessment of the Binding of 18 Putative Transition-State Mimics. J.Am.Chem.Soc., 129, 2007
4Q3P	Crystal structure of Schistosoma mansoni arginase 分子名称: Arginase, GLYCEROL, MANGANESE (II) ION 著者 Hai, Y, Edwards, J.E, Van Zandt, M.C, Hoffmann, K.F, Christianson, D.W. 登録日 2014-04-12 公開日 2014-07-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.501 Å) 主引用文献 Crystal Structure of Schistosoma mansoni Arginase, a Potential Drug Target for the Treatment of Schistosomiasis. Biochemistry, 53, 2014
2IGK	Crystal structure of recombinant pyranose 2-oxidase 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, Pyranose oxidase 著者 Divne, C. 登録日 2006-09-22 公開日 2006-10-10 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural basis for substrate binding and regioselective oxidation of monosaccharides at c3 by pyranose 2-oxidase. J.Biol.Chem., 281, 2006
6GVS	Engineered glycolyl-CoA reductase comprising 8 mutations with bound NADP+ 分子名称: Aldehyde dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM ION 著者 Zarzycki, J, Trudeau, D, Scheffen, M, Erb, T.J, Tawfik, D.S. 登録日 2018-06-21 公開日 2018-11-28 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.579 Å) 主引用文献 Design and in vitro realization of carbon-conserving photorespiration. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6AJ5	Crystal structure of ligand-free type DHODH from Eimeria tenella 分子名称: Dihydroorotate dehydrogenase (quinone), mitochondrial, FLAVIN MONONUCLEOTIDE, ... 著者 Shiba, T, Inaoka, D.K, Sato, D, Hartuti, E.D, Amalia, E, Nagahama, M, Yoshioka, Y, Matsubayashi, M, Balogun, E.O, Tsuji, N, Kita, K, Harada, S. 登録日 2018-08-27 公開日 2019-08-28 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Structural and Biochemical Features of Eimeria tenella Dihydroorotate Dehydrogenase, a Potential Drug Target. Genes (Basel), 11, 2020

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