8JLY
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8JLI
| Cryo-EM structure of SV2A dimer in complex levetiracetam | 分子名称: | (2S)-2-(2-oxidanylidenepyrrolidin-1-yl)butanamide, Synaptic vesicle glycoprotein 2A | 著者 | Yamagata, A. | 登録日 | 2023-06-02 | 公開日 | 2024-05-01 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.38 Å) | 主引用文献 | Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A. Nat Commun, 15, 2024
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8JLH
| Cryo-EM structure of SV2A dimer in complex with BoNT/A2 Hc and levetiracetam | 分子名称: | (2S)-2-(2-oxidanylidenepyrrolidin-1-yl)butanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Yamagata, A. | 登録日 | 2023-06-02 | 公開日 | 2024-05-01 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A. Nat Commun, 15, 2024
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8JLG
| Cryo-EM structure of SV2A in complex with BoNT/A2 Hc | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Botulinum neurotoxin, ... | 著者 | Yamagata, A. | 登録日 | 2023-06-02 | 公開日 | 2024-05-01 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (2.87 Å) | 主引用文献 | Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A. Nat Commun, 15, 2024
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8JLF
| Cryo-EM structure of SV2A in complex with BoNT/A2 Hc | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Botulinum neurotoxin, ... | 著者 | Yamagata, A. | 登録日 | 2023-06-02 | 公開日 | 2024-05-01 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | 主引用文献 | Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A. Nat Commun, 15, 2024
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8JLE
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8JLD
| Cryo-EM structure of the 145 bp human nucleosome containing acetylated H3 tail | 分子名称: | DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | 著者 | Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H. | 登録日 | 2023-06-02 | 公開日 | 2023-10-04 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (2.48 Å) | 主引用文献 | Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II. Nucleic Acids Res., 51, 2023
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8JLC
| Cryo-EM structure of SV2A in complex with BoNT/A2 Hc and levetiracetam | 分子名称: | (2S)-2-(2-oxidanylidenepyrrolidin-1-yl)butanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Yamagata, A. | 登録日 | 2023-06-02 | 公開日 | 2024-05-01 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (2.88 Å) | 主引用文献 | Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A. Nat Commun, 15, 2024
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8JLB
| Cryo-EM structure of the 145 bp human nucleosome containing H3.2 C110A mutant | 分子名称: | DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | 著者 | Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H. | 登録日 | 2023-06-02 | 公開日 | 2023-10-04 | 最終更新日 | 2023-11-08 | 実験手法 | ELECTRON MICROSCOPY (2.36 Å) | 主引用文献 | Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II. Nucleic Acids Res., 51, 2023
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8JLA
| Cryo-EM structure of the human nucleosome lacking N-terminal region of H2A, H2B, H3, and H4 | 分子名称: | DNA (193-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | 著者 | Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H. | 登録日 | 2023-06-02 | 公開日 | 2023-10-04 | 最終更新日 | 2023-11-08 | 実験手法 | ELECTRON MICROSCOPY (3.44 Å) | 主引用文献 | Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II. Nucleic Acids Res., 51, 2023
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8JL9
| Cryo-EM structure of the human nucleosome with scFv | 分子名称: | DNA (193-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | 著者 | Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H. | 登録日 | 2023-06-02 | 公開日 | 2023-10-04 | 最終更新日 | 2023-11-08 | 実験手法 | ELECTRON MICROSCOPY (2.65 Å) | 主引用文献 | Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II. Nucleic Acids Res., 51, 2023
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8JL8
| Crystal structure of the collagen binding domain of Cnm from Streptococcus mutans | 分子名称: | Collagen-binding adhesin, GLYCEROL, SULFATE ION | 著者 | Tanaka, S.-i, Hirata, A, Takano, K. | 登録日 | 2023-06-02 | 公開日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | Structure, Stability and Binding Properties of Collagen-Binding Domains from Streptococcus mutans. Chemistry, 5, 2023
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8JKR
| SP1746 in complex with UMP | 分子名称: | 1,2-ETHANEDIOL, FE (III) ION, GLYCEROL, ... | 著者 | Jin, Y, Niu, L, Ke, J. | 登録日 | 2023-06-01 | 公開日 | 2024-05-08 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural and biochemical characterization of a nucleotide hydrolase from Streptococcus pneumonia. Structure, 2024
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8JKP
| SP1746 in complex with dTMP | 分子名称: | FE (III) ION, GLYCEROL, SULFATE ION, ... | 著者 | Jin, Y, Ke, J, Niu, L. | 登録日 | 2023-06-01 | 公開日 | 2024-05-08 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural and biochemical characterization of a nucleotide hydrolase from Streptococcus pneumonia. Structure, 2024
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8JK9
| SP1746 in complex with GDP | 分子名称: | FE (III) ION, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Jin, Y, Ke, J, Niu, L. | 登録日 | 2023-06-01 | 公開日 | 2024-05-08 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural and biochemical characterization of a nucleotide hydrolase from Streptococcus pneumonia. Structure, 2024
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8JK8
| SP1746 in complex with UDP | 分子名称: | 1,2-ETHANEDIOL, FE (III) ION, GLYCEROL, ... | 著者 | Jin, Y, Niu, L, Ke, J. | 登録日 | 2023-06-01 | 公開日 | 2024-05-08 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural and biochemical characterization of a nucleotide hydrolase from Streptococcus pneumonia. Structure, 2024
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8JK5
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8JK3
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8JJV
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8JJS
| Human K-Ras G12D (GDP-bound) in complex with cyclic peptide inhibitor AP10343 | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, MAA-ILE-SAR-SAR-7T2-SAR-IAE-LEU-MEA-MLE-7TK, ... | 著者 | Irie, M, Fukami, T.A, Tanada, M, Ohta, A, Torizawa, T. | 登録日 | 2023-05-31 | 公開日 | 2023-07-26 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.534 Å) | 主引用文献 | Development of Orally Bioavailable Peptides Targeting an Intracellular Protein: From a Hit to a Clinical KRAS Inhibitor. J.Am.Chem.Soc., 145, 2023
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8JJR
| Cryo-EM structure of Symbiodinium photosystem I | 分子名称: | (3S,3'R,5R,6S,7cis)-7',8'-didehydro-5,6-dihydro-5,6-epoxy-beta,beta-carotene-3,3'-diol, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ... | 著者 | Zhao, L.S, Wang, N, Li, K, Zhang, Y.Z, Liu, L.N. | 登録日 | 2023-05-31 | 公開日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Architecture of symbiotic dinoflagellate photosystem I-light-harvesting supercomplex in Symbiodinium. Nat Commun, 15, 2024
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8JJO
| Cryo-EM structure of the beta2AR-mBRIL/1b3 Fab/Glue complex with an antagonist | 分子名称: | (2S)-1-[(1-methylethyl)amino]-3-(2-prop-2-en-1-ylphenoxy)propan-2-ol, Beta-2 adrenergic receptor,Beta-2 adrenergic receptor,Soluble cytochrome b562 | 著者 | He, B.B, Zhong, Y.X, Guo, Q, Tao, Y.Y. | 登録日 | 2023-05-31 | 公開日 | 2023-09-06 | 最終更新日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | A method for structure determination of GPCRs in various states. Nat.Chem.Biol., 20, 2024
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8JJN
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8JJM
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8JJK
| SP1746 in complex with ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, FE (III) ION, GLYCEROL, ... | 著者 | Jin, Y, Niu, L, Ke, J. | 登録日 | 2023-05-30 | 公開日 | 2024-05-08 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural and biochemical characterization of a nucleotide hydrolase from Streptococcus pneumonia. Structure, 2024
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