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6F2H
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BU of 6f2h by Molmil
Structure of Protease 1 from Pyrococcus horikoshii co-crystallized in presence of 10 mM Tb-Xo4 and potassium iodide.
分子名称: Deglycase PH1704, IODIDE ION, TERBIUM(III) ION, ...
著者Engilberge, S, Riobe, F, Di Pietro, S, Franzetti, B, Girard, E, Dumont, E, Maury, O.
登録日2017-11-24
公開日2018-10-03
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Unveiling the Binding Modes of the Crystallophore, a Terbium-based Nucleating and Phasing Molecular Agent for Protein Crystallography.
Chemistry, 24, 2018
6BHG
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BU of 6bhg by Molmil
Crystal structure of SETDB1 with a modified H3 peptide
分子名称: Histone H3.1, Histone-lysine N-methyltransferase SETDB1, UNKNOWN ATOM OR ION
著者Qin, S, Tempel, W, Dong, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2017-10-30
公開日2017-12-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1.
Nat Commun, 8, 2017
6POU
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BU of 6pou by Molmil
Structure of human endothelial nitric oxide synthase heme domain in complex with 7-(4-(2-Aminoethyl)phenyl)-4-methylquinolin-2-amine
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 7-[4-(2-aminoethyl)phenyl]-4-methylquinolin-2-amine, GADOLINIUM ATOM, ...
著者Li, H, Poulos, T.L.
登録日2019-07-05
公開日2020-04-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.194 Å)
主引用文献First Contact: 7-Phenyl-2-Aminoquinolines, Potent and Selective Neuronal Nitric Oxide Synthase Inhibitors That Target an Isoform-Specific Aspartate.
J.Med.Chem., 63, 2020
6F38
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BU of 6f38 by Molmil
Cryo-EM structure of two dynein tail domains bound to dynactin and HOOK3
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ARP1 actin related protein 1 homolog A, ...
著者Lau, C.K, Urnavicius, L, Elshenawy, M.M, Morales-Rios, E, Motz, C, Yildiz, A, Carter, A.P.
登録日2017-11-28
公開日2018-01-17
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (6.7 Å)
主引用文献Cryo-EM shows how dynactin recruits two dyneins for faster movement.
Nature, 554, 2018
6BGL
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BU of 6bgl by Molmil
Doubly PafE-capped 20S core particle in Mycobacterium tuberculosis
分子名称: Bacterial proteasome activator, Proteasome subunit alpha, Proteasome subunit beta
著者Li, H, Hu, K.
登録日2017-10-28
公開日2018-02-14
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Proteasome substrate capture and gate opening by the accessory factor PafE fromMycobacterium tuberculosis.
J. Biol. Chem., 293, 2018
8WFJ
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BU of 8wfj by Molmil
human glycine transporter 1 in complex with ALX-5407 in inward facing conformation
分子名称: ALX5407, Sodium- and chloride-dependent glycine transporter 1
著者Wei, Y, Zhao, Y.
登録日2023-09-19
公開日2024-04-03
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Transport mechanism and pharmacology of the human GlyT1.
Cell, 187, 2024
6F7U
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BU of 6f7u by Molmil
Molecular Mechanism of ATP versus GTP Selectivity of Adenylate Kinase
分子名称: Adenylate kinase, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER
著者Rogne, P, Rosselin, M, Grundstrom, C, Hedberg, C, Wolf-Watz, M, Sauer, U.H.
登録日2017-12-12
公開日2018-03-14
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Molecular mechanism of ATP versus GTP selectivity of adenylate kinase.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
8WLO
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BU of 8wlo by Molmil
Cryo-EM structure of SARS-CoV-2 prototype spike protein in complex with hippopotamus ACE2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, ...
著者Han, P, Yang, R.R, Li, S.H.
登録日2023-09-30
公開日2024-03-27
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.62 Å)
主引用文献Molecular basis of hippopotamus ACE2 binding to SARS-CoV-2.
J.Virol., 98, 2024
6YNX
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BU of 6ynx by Molmil
Cryo-EM structure of Tetrahymena thermophila mitochondrial ATP synthase - Fo-subcomplex
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Kock Flygaard, R, Muhleip, A, Amunts, A.
登録日2020-04-14
公開日2020-09-30
最終更新日2020-11-11
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Type III ATP synthase is a symmetry-deviated dimer that induces membrane curvature through tetramerization.
Nat Commun, 11, 2020
6YRC
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BU of 6yrc by Molmil
Spectroscopically-validated structure of DtpB from Streptomyces lividans in the ferric state
分子名称: 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, GLYCEROL, MAGNESIUM ION, ...
著者Lucic, M, Dworkowski, F.S.N, Worrall, J.A.R, Hough, M.A.
登録日2020-04-20
公開日2021-01-13
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Serial Femtosecond Zero Dose Crystallography Captures a Water-Free Distal Heme Site in a Dye-Decolorising Peroxidase to Reveal a Catalytic Role for an Arginine in Fe IV =O Formation.
Angew.Chem.Int.Ed.Engl., 59, 2020
8WFL
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BU of 8wfl by Molmil
human glycine transporter 1 in complex with PF-03463275 in outward facing conformation
分子名称: PF-3463275, Sodium- and chloride-dependent glycine transporter 1
著者Wei, Y, Zhao, Y.
登録日2023-09-19
公開日2024-04-03
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (3.03 Å)
主引用文献Transport mechanism and pharmacology of the human GlyT1.
Cell, 187, 2024
1S7E
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BU of 1s7e by Molmil
Solution structure of HNF-6
分子名称: Hepatocyte nuclear factor 6
著者Liao, X, Sheng, W.
登録日2004-01-29
公開日2004-12-28
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of the hepatocyte nuclear factor 6alpha and its interaction with DNA.
J.Biol.Chem., 279, 2004
2MJS
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BU of 2mjs by Molmil
Anoplin R5K T8W in DPC micelles
分子名称: Anoplin, UNKNOWN ATOM OR ION, dodecyl 2-(trimethylammonio)ethyl phosphate
著者Uggerhoej, L, Poulsen, T.J, Wimmer, R.
登録日2014-01-16
公開日2014-12-03
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Rational Design of Alpha-Helical Antimicrobial Peptides: Do's and Don'ts.
Chembiochem, 16, 2015
6Y69
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BU of 6y69 by Molmil
Cryo-EM structure of an Escherichia coli 70S ribosome in complex with antibiotic TetracenomycinX
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Wieland, M, Wilson, D.N.
登録日2020-02-26
公開日2020-07-01
最終更新日2023-11-08
実験手法ELECTRON MICROSCOPY (2.86 Å)
主引用文献Tetracenomycin X inhibits translation by binding within the ribosomal exit tunnel.
Nat.Chem.Biol., 16, 2020
6CD9
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BU of 6cd9 by Molmil
GID4 in complex with a peptide
分子名称: Glucose-induced degradation protein 4 homolog, Tetrapeptide PSRW, UNKNOWN ATOM OR ION
著者Dong, C, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2018-02-08
公開日2018-03-07
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Molecular basis of GID4-mediated recognition of degrons for the Pro/N-end rule pathway.
Nat. Chem. Biol., 14, 2018
6Y3D
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BU of 6y3d by Molmil
X-ray structure of thermophilic C-phycocyanin from Galdiera phlegrea
分子名称: ACETATE ION, C-phycocyanin alpha chain, C-phycocyanin beta chain, ...
著者Ferraro, G, Lucignano, R, Marseglia, A, Merlino, A.
登録日2020-02-18
公開日2020-12-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献X-ray structure of C-phycocyanin from Galdieria phlegrea: Determinants of thermostability and comparison with a C-phycocyanin in the entire phycobilisome.
Biochim Biophys Acta Bioenerg, 1861, 2020
5KLI
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BU of 5kli by Molmil
Rhodobacter sphaeroides bc1 with stigmatellin and antimycin
分子名称: (1R)-2-{[(R)-(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(DODECANOYLOXY)METHYL]ETHYL (9Z)-OCTADEC-9-ENOATE, (2R,3S,6S,7R,8R)-3-{[3-(FORMYLAMINO)-2-HYDROXYBENZOYL]AMINO}-8-HEXYL-2,6-DIMETHYL-4,9-DIOXO-1,5-DIOXONAN-7-YL (2S)-2-METHYLBUTANOATE, Cytochrome b, ...
著者Xia, D, Esser, L, Zhou, F, Tang, W.K, Yu, C.A.
登録日2016-06-24
公開日2016-10-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.996 Å)
主引用文献Hydrogen Bonding to the Substrate Is Not Required for Rieske Iron-Sulfur Protein Docking to the Quinol Oxidation Site of Complex III.
J.Biol.Chem., 291, 2016
6YBS
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BU of 6ybs by Molmil
Structure of a human 48S translational initiation complex - head
分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S12, ...
著者Brito Querido, J, Sokabe, M, Kraatz, S, Gordiyenko, Y, Skehel, M, Fraser, C, Ramakrishnan, V.
登録日2020-03-17
公開日2020-09-16
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structure of a human 48Stranslational initiation complex.
Science, 369, 2020
6CV6
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BU of 6cv6 by Molmil
Crystal structure of 3-dehydroquinate dehydratase, type II, from Burkholderia phymatum STM815
分子名称: 3-dehydroquinate dehydratase, CHLORIDE ION, D(-)-TARTARIC ACID, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2018-03-27
公開日2018-04-11
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of 3-dehydroquinate dehydratase, type II, from Burkholderia phymatum STM815
to be published
6PTS
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BU of 6pts by Molmil
NMR data-driven model of KRas-GMPPNP:RBD-CRD complex tethered to a nanodisc (state A)
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Apolipoprotein A-I, GTPase KRas, ...
著者Fang, Z, Lee, K, Gasmi-Seabrook, G, Ikura, M, Marshall, C.B.
登録日2019-07-16
公開日2020-05-13
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Multivalent assembly of KRAS with the RAS-binding and cysteine-rich domains of CRAF on the membrane.
Proc.Natl.Acad.Sci.USA, 117, 2020
8VRK
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BU of 8vrk by Molmil
Rigid body fitted model for refined density map of gamma tubulin ring complex capped microtubule
分子名称: Actin, cytoplasmic 1, Gamma-tubulin complex component 3, ...
著者Aher, A, Urnavicius, L, Kapoor, T.M.
登録日2024-01-22
公開日2024-03-27
最終更新日2024-07-31
実験手法ELECTRON MICROSCOPY (8.5 Å)
主引用文献Structure of the gamma-tubulin ring complex-capped microtubule.
Nat.Struct.Mol.Biol., 31, 2024
6YDP
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BU of 6ydp by Molmil
55S mammalian mitochondrial ribosome with mtEFG1 and P site fMet-tRNAMet (POST)
分子名称: 12S rRNA, 28S ribosomal protein S16, mitochondrial, ...
著者Kummer, E, Ban, N.
登録日2020-03-20
公開日2020-07-15
最終更新日2020-08-12
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural insights into mammalian mitochondrial translation elongation catalyzed by mtEFG1.
Embo J., 39, 2020
8VRJ
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BU of 8vrj by Molmil
Rigid body fitted model for gamma tubulin ring complex capped microtubule
分子名称: Actin, cytoplasmic 1, Gamma-tubulin complex component 3, ...
著者Aher, A, Urnavicius, L, Kapoor, T.M.
登録日2024-01-22
公開日2024-03-27
最終更新日2024-07-31
実験手法ELECTRON MICROSCOPY (7.7 Å)
主引用文献Structure of the gamma-tubulin ring complex-capped microtubule.
Nat.Struct.Mol.Biol., 31, 2024
6CI9
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BU of 6ci9 by Molmil
RMM microcompartment-associated aminopropanol dehydrogenase NADP + aminoacetone holo-structure
分子名称: 1-aminopropan-2-one, 3-oxoacyl-[acyl-carrier-protein] reductase, CHLORIDE ION, ...
著者Mallette, E, Kimber, M.S.
登録日2018-02-23
公開日2018-05-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure and Kinetics of the S-(+)-1-Amino-2-propanol Dehydrogenase from the RMM Microcompartment of Mycobacterium smegmatis.
Biochemistry, 57, 2018
5KPX
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BU of 5kpx by Molmil
Structure of RelA bound to ribosome in presence of A/R tRNA (Structure IV)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Loveland, A.B, Bah, E, Madireddy, R, Zhang, Y, Brilot, A.F, Grigorieff, N, Korostelev, A.A.
登録日2016-07-05
公開日2016-09-28
最終更新日2019-11-20
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Ribosome•RelA structures reveal the mechanism of stringent response activation.
Elife, 5, 2016

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